Published in Cancer Res on November 01, 2007
Doxorubicin cardiomyopathy. Cardiology (2009) 1.99
ERKs/p53 signal transduction pathway is involved in doxorubicin-induced apoptosis in H9c2 cells and cardiomyocytes. Am J Physiol Heart Circ Physiol (2008) 1.54
Potent anti-inflammatory and antinociceptive activity of the endothelin receptor antagonist bosentan in monoarthritic mice. Arthritis Res Ther (2011) 1.42
Cancer therapy-induced cardiac toxicity in early breast cancer: addressing the unresolved issues. Circulation (2012) 1.14
An engineered bivalent neuregulin protects against doxorubicin-induced cardiotoxicity with reduced proneoplastic potential. Circulation (2013) 1.06
Endothelin B receptor, a new target in cancer immune therapy. Clin Cancer Res (2009) 1.05
Cell signaling pathways for the regulation of GATA4 transcription factor: Implications for cell growth and apoptosis. Cell Signal (2011) 0.96
Schisandrin B prevents doxorubicin induced cardiac dysfunction by modulation of DNA damage, oxidative stress and inflammation through inhibition of MAPK/p53 signaling. PLoS One (2015) 0.88
Efficacy and mechanism of angiotensin II receptor blocker treatment in experimental abdominal aortic aneurysms. PLoS One (2012) 0.87
Mechanisms of anthracycline cardiotoxicity and strategies to decrease cardiac damage. Curr Hypertens Rep (2010) 0.83
Prognostic role of troponin and natriuretic peptides as biomarkers for deterioration of left ventricular ejection fraction after chemotherapy. Arch Med Sci (2013) 0.81
The tell-tale heart: molecular and cellular responses to childhood anthracycline exposure. Am J Physiol Heart Circ Physiol (2014) 0.79
Anti-Fas gene therapy prevents doxorubicin-induced acute cardiotoxicity through mechanisms independent of apoptosis. Am J Pathol (2009) 0.79
Interleukin-6 and tumor necrosis factor-α are associated with quality of life-related symptoms in pulmonary arterial hypertension. Ann Am Thorac Soc (2015) 0.79
Signaling Pathways in Cardiac Myocyte Apoptosis. Biomed Res Int (2016) 0.76
Bosentan: a rapidly expanding role in the management of cardio-thoracic diseases. Rheumatol Int (2008) 0.75
Scientific validation of cardioprotective attribute by standardized extract of Bombyx mori against doxorubicin-induced cardiotoxicity in murine model. EXCLI J (2014) 0.75
Doxorubicin induced heart failure: Phenotype and molecular mechanisms. Int J Cardiol Heart Vasc (2016) 0.75
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Scleroderma. N Engl J Med (2009) 6.50
A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat Genet (2009) 6.31
Clinical Features and Outcomes of Takotsubo (Stress) Cardiomyopathy. N Engl J Med (2015) 6.00
New loci associated with kidney function and chronic kidney disease. Nat Genet (2010) 5.58
Inflammation in wound repair: molecular and cellular mechanisms. J Invest Dermatol (2007) 5.16
Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas. Proc Natl Acad Sci U S A (2003) 5.08
A novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation. J Am Coll Cardiol (2013) 5.04
Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. PLoS Genet (2009) 4.97
Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases. J Clin Invest (2002) 4.64
Detection of viruses in myocardial tissues by polymerase chain reaction. evidence of adenovirus as a common cause of myocarditis in children and adults. J Am Coll Cardiol (2003) 4.51
Condition-dependent transcriptome reveals high-level regulatory architecture in Bacillus subtilis. Science (2012) 4.41
Cohort profile: the study of health in Pomerania. Int J Epidemiol (2010) 4.38
Herceptin-induced inhibition of phosphatidylinositol-3 kinase and Akt Is required for antibody-mediated effects on p27, cyclin D1, and antitumor action. Cancer Res (2002) 4.36
Anticoagulation and survival in pulmonary arterial hypertension: results from the Comparative, Prospective Registry of Newly Initiated Therapies for Pulmonary Hypertension (COMPERA). Circulation (2013) 3.90
Utility of Doppler echocardiography and tissue Doppler imaging in the estimation of diastolic function in heart failure with normal ejection fraction: a comparative Doppler-conductance catheterization study. Circulation (2007) 3.76
Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nat Genet (2012) 3.71
Role of left ventricular stiffness in heart failure with normal ejection fraction. Circulation (2008) 3.56
Differential roles of macrophages in diverse phases of skin repair. J Immunol (2010) 3.56
Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nat Genet (2010) 3.55
Keratinocyte-fibroblast interactions in wound healing. J Invest Dermatol (2007) 3.51
Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. Eur Heart J (2013) 3.50
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
Loss of PTEN/MMAC1/TEP in EGF receptor-expressing tumor cells counteracts the antitumor action of EGFR tyrosine kinase inhibitors. Oncogene (2003) 3.32
TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2. Nature (2002) 3.21
Identification of genetic loci associated with Helicobacter pylori serologic status. JAMA (2013) 3.15
New gene functions in megakaryopoiesis and platelet formation. Nature (2011) 3.14
Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I. Nat Med (2013) 3.10
High prevalence of viral genomes and multiple viral infections in the myocardium of adults with "idiopathic" left ventricular dysfunction. Circulation (2005) 3.06
Multiple, brief coronary occlusions during early reperfusion protect rabbit hearts by targeting cell signaling pathways. J Am Coll Cardiol (2004) 2.94
Seventy-five genetic loci influencing the human red blood cell. Nature (2012) 2.77
SigB-dependent general stress response in Bacillus subtilis and related gram-positive bacteria. Annu Rev Microbiol (2007) 2.73
E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions. EMBO J (2005) 2.72
CUBN is a gene locus for albuminuria. J Am Soc Nephrol (2011) 2.70
Muscle wasting in patients with chronic heart failure: results from the studies investigating co-morbidities aggravating heart failure (SICA-HF). Eur Heart J (2012) 2.60
T cell-specific inactivation of the interleukin 10 gene in mice results in enhanced T cell responses but normal innate responses to lipopolysaccharide or skin irritation. J Exp Med (2004) 2.58
Protective role of angiopoietin-1 in endotoxic shock. Circulation (2004) 2.53
CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair. Blood (2012) 2.43
Mast cells are key promoters of contact allergy that mediate the adjuvant effects of haptens. Immunity (2011) 2.39
Cytomegalovirus (CMV) phosphoprotein 65 makes a large contribution to shaping the T cell repertoire in CMV-exposed individuals. J Infect Dis (2002) 2.33
Interferon-beta treatment eliminates cardiotropic viruses and improves left ventricular function in patients with myocardial persistence of viral genomes and left ventricular dysfunction. Circulation (2003) 2.33
Cardiac inflammation contributes to changes in the extracellular matrix in patients with heart failure and normal ejection fraction. Circ Heart Fail (2010) 2.30
Viral persistence in the myocardium is associated with progressive cardiac dysfunction. Circulation (2005) 2.15
Impact of atrial fibrillation on the accuracy of oscillometric blood pressure monitoring. Hypertension (2013) 2.10
Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. JAMA (2009) 2.10
Procoagulant soluble tissue factor is released from endothelial cells in response to inflammatory cytokines. Circ Res (2005) 2.09
Novel activities of glycolytic enzymes in Bacillus subtilis: interactions with essential proteins involved in mRNA processing. Mol Cell Proteomics (2009) 2.08
Parvovirus B19 infection mimicking acute myocardial infarction. Circulation (2003) 2.03
Glyburide and glimepiride pharmacokinetics in subjects with different CYP2C9 genotypes. Clin Pharmacol Ther (2002) 2.01
Hepatitis B and C virus infection and the risk of atherosclerosis in a general population. Atherosclerosis (2004) 2.01
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis. Microbiology (2005) 1.99
CYP2D6 genotype and induction of intestinal drug transporters by rifampin predict presystemic clearance of carvedilol in healthy subjects. Clin Pharmacol Ther (2004) 1.99
Riociguat for patients with pulmonary hypertension caused by systolic left ventricular dysfunction: a phase IIb double-blind, randomized, placebo-controlled, dose-ranging hemodynamic study. Circulation (2013) 1.94
De novo acute heart failure and acutely decompensated chronic heart failure. Dtsch Arztebl Int (2015) 1.93
Comment on "A common genetic variant is associated with adult and childhood obesity". Science (2007) 1.93
Low serum testosterone levels are associated with increased risk of mortality in a population-based cohort of men aged 20-79. Eur Heart J (2010) 1.88
Myocarditis: early biopsy allows for tailored regenerative treatment. Dtsch Arztebl Int (2012) 1.88
Suspected chronic myocarditis at cardiac MR: diagnostic accuracy and association with immunohistologically detected inflammation and viral persistence. Radiology (2008) 1.87
A genome-wide association study of metabolic traits in human urine. Nat Genet (2011) 1.84
Cardiac deletion of the Coxsackievirus-adenovirus receptor abolishes Coxsackievirus B3 infection and prevents myocarditis in vivo. J Am Coll Cardiol (2009) 1.81
Renin inhibition improves cardiac function and remodeling after myocardial infarction independent of blood pressure. Hypertension (2008) 1.78
A comprehensive proteome map of growing Bacillus subtilis cells. Proteomics (2004) 1.78
Complications of right heart catheterization procedures in patients with pulmonary hypertension in experienced centers. J Am Coll Cardiol (2006) 1.76
Deposition of Alzheimer's beta-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans. Pharmacogenetics (2002) 1.75
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet (2013) 1.72
Outcome after cardiopulmonary resuscitation in patients with pulmonary arterial hypertension. Am J Respir Crit Care Med (2002) 1.72