Under-reporting of adverse effects of tesofensine.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 23849924)

Published in Lancet on July 13, 2013

Authors

Arne Astrup, Sten Madsbad, Leif Breum, Thomas J Jensen, Jens P Kroustrup, Thomas M Larsen

Articles citing this

New targets to treat obesity and the metabolic syndrome. Eur J Pharmacol (2015) 0.77

Articles by these authors

A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management. N Engl J Med (2015) 11.05

Angiotensin-receptor blockade versus converting-enzyme inhibition in type 2 diabetes and nephropathy. N Engl J Med (2004) 6.21

Diets with high or low protein content and glycemic index for weight-loss maintenance. N Engl J Med (2010) 5.86

Efficacy and safety of the weight-loss drug rimonabant: a meta-analysis of randomised trials. Lancet (2007) 5.49

Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants. Nat Genet (2010) 5.44

Myths, presumptions, and facts about obesity. N Engl J Med (2013) 5.39

Concern Effect of tesofensine on bodyweight loss, body composition, and quality of life in obese patients: a randomised, double-blind, placebo-controlled trial. Lancet (2008) 4.41

Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: a parallel-group study. Lancet (2002) 4.29

Effect of weight reduction in obese patients diagnosed with knee osteoarthritis: a systematic review and meta-analysis. Ann Rheum Dis (2007) 3.70

Sucrose compared with artificial sweeteners: different effects on ad libitum food intake and body weight after 10 wk of supplementation in overweight subjects. Am J Clin Nutr (2002) 3.25

No difference in body weight decrease between a low-glycemic-index and a high-glycemic-index diet but reduced LDL cholesterol after 10-wk ad libitum intake of the low-glycemic-index diet. Am J Clin Nutr (2004) 3.08

Liraglutide, a long-acting human glucagon-like peptide-1 analog, given as monotherapy significantly improves glycemic control and lowers body weight without risk of hypoglycemia in patients with type 2 diabetes. Diabetes Care (2007) 2.92

Regulation of adiponectin by adipose tissue-derived cytokines: in vivo and in vitro investigations in humans. Am J Physiol Endocrinol Metab (2003) 2.71

Sucrose-sweetened beverages increase fat storage in the liver, muscle, and visceral fat depot: a 6-mo randomized intervention study. Am J Clin Nutr (2011) 2.47

Sleep restriction is not associated with a positive energy balance in adolescent boys. Am J Clin Nutr (2012) 2.38

Protein, weight management, and satiety. Am J Clin Nutr (2008) 2.34

Reduced incretin effect in type 2 diabetes: cause or consequence of the diabetic state? Diabetes (2007) 2.24

Effect of weight loss on the severity of psoriasis: a randomized clinical study. JAMA Dermatol (2013) 2.18

The influence of GLP-1 on glucose-stimulated insulin secretion: effects on beta-cell sensitivity in type 2 and nondiabetic subjects. Diabetes (2003) 2.16

Comparison of 3 ad libitum diets for weight-loss maintenance, risk of cardiovascular disease, and diabetes: a 6-mo randomized, controlled trial. Am J Clin Nutr (2008) 1.97

Video game playing increases food intake in adolescents: a randomized crossover study. Am J Clin Nutr (2011) 1.92

Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects. Regul Pept (2003) 1.91

Effects of weight loss and long-term weight maintenance with diets varying in protein and glycemic index on cardiovascular risk factors: the diet, obesity, and genes (DiOGenes) study: a randomized, controlled trial. Circulation (2011) 1.88

The use of glycaemic index tables to predict glycaemic index of composite breakfast meals. Br J Nutr (2004) 1.74

High levels of industrially produced trans fat in popular fast foods. N Engl J Med (2006) 1.74

Insulin resistance, the metabolic syndrome, and risk of incident cardiovascular disease: a population-based study. J Am Coll Cardiol (2007) 1.73

Obesity and the metabolic syndrome: role of different dietary macronutrient distribution patterns and specific nutritional components on weight loss and maintenance. Nutr Rev (2010) 1.71

Exaggerated glucagon-like peptide 1 response is important for improved β-cell function and glucose tolerance after Roux-en-Y gastric bypass in patients with type 2 diabetes. Diabetes (2013) 1.66

Effect of protein intake on bone mineralization during weight loss: a 6-month trial. Obes Res (2002) 1.64

A trans world journey. Atheroscler Suppl (2006) 1.61

Effects of everyday life events on glucose, insulin, and glucagon dynamics in continuous subcutaneous insulin infusion-treated type 1 diabetes: collection of clinical data for glucose modeling. Diabetes Technol Ther (2011) 1.55

Impact of short-term high-fat feeding on glucose and insulin metabolism in young healthy men. J Physiol (2009) 1.52

Sleep duration as a risk factor for the development of type 2 diabetes or impaired glucose tolerance: analyses of the Quebec Family Study. Sleep Med (2009) 1.49

FTO gene associated fatness in relation to body fat distribution and metabolic traits throughout a broad range of fatness. PLoS One (2008) 1.49

Effects of PYY1-36 and PYY3-36 on appetite, energy intake, energy expenditure, glucose and fat metabolism in obese and lean subjects. Am J Physiol Endocrinol Metab (2006) 1.49

Effect of sucrose on inflammatory markers in overweight humans. Am J Clin Nutr (2005) 1.48

Effect of trans-fatty acid intake on insulin sensitivity and intramuscular lipids--a randomized trial in overweight postmenopausal women. Metabolism (2011) 1.47

Glucagon-like peptide-1, glucose homeostasis and diabetes. Trends Mol Med (2008) 1.46

The use of glycaemic index tables to predict glycaemic index of breakfast meals. Br J Nutr (2005) 1.45

Measuring the glycemic index of foods: interlaboratory study. Am J Clin Nutr (2008) 1.44

Meals with similar energy densities but rich in protein, fat, carbohydrate, or alcohol have different effects on energy expenditure and substrate metabolism but not on appetite and energy intake. Am J Clin Nutr (2003) 1.44

[The CARMEN trial: increased intake of carbohydrates--simple or complex--and unchanged blood lipids in overweight subjects]. Ugeskr Laeger (2002) 1.40

[The place of Glitazones in the treatment of diabetes: after the PROactive study]. Ugeskr Laeger (2006) 1.38

Long-term effects on haemostatic variables of three ad libitum diets differing in type and amount of fat and carbohydrate: a 6-month randomised study in obese individuals. Br J Nutr (2010) 1.38

Deoxyribonucleic acid methylation and gene expression of PPARGC1A in human muscle is influenced by high-fat overfeeding in a birth-weight-dependent manner. J Clin Endocrinol Metab (2010) 1.35

Plasma dipeptidyl peptidase-IV activity in patients with type-2 diabetes mellitus correlates positively with HbAlc levels, but is not acutely affected by food intake. Eur J Endocrinol (2006) 1.34

G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans. Diabetes (2009) 1.27

Total and regional fat distribution is strongly influenced by genetic factors in young and elderly twins. Obes Res (2005) 1.26

Association between measures of insulin sensitivity and circulating levels of interleukin-8, interleukin-6 and tumor necrosis factor-alpha. Effect of weight loss in obese men. Eur J Endocrinol (2003) 1.26

Postprandial diabetic glucose tolerance is normalized by gastric bypass feeding as opposed to gastric feeding and is associated with exaggerated GLP-1 secretion: a case report. Diabetes Care (2009) 1.25

The effect of liraglutide, a long-acting glucagon-like peptide 1 derivative, on glycemic control, body composition, and 24-h energy expenditure in patients with type 2 diabetes. Diabetes Care (2004) 1.24

Diet composition and obesity. Lancet (2012) 1.23

Starches, sugars and obesity. Nutrients (2011) 1.23

Associations between postprandial insulin and blood glucose responses, appetite sensations and energy intake in normal weight and overweight individuals: a meta-analysis of test meal studies. Br J Nutr (2007) 1.23

Early enhancements of hepatic and later of peripheral insulin sensitivity combined with increased postprandial insulin secretion contribute to improved glycemic control after Roux-en-Y gastric bypass. Diabetes (2013) 1.22

GLP-1: physiological effects and potential therapeutic applications. Diabetes Obes Metab (2008) 1.22

Incretin-based therapies: viewpoints on the way to consensus. Diabetes Care (2009) 1.22

Four weeks of treatment with liraglutide reduces insulin dose without loss of glycemic control in type 1 diabetic patients with and without residual beta-cell function. Diabetes Care (2011) 1.22

Fat oxidation before and after a high fat load in the obese insulin-resistant state. J Clin Endocrinol Metab (2006) 1.21

Genotype-phenotype associations in obesity dependent on definition of the obesity phenotype. Obes Facts (2008) 1.17

Loss of incretin effect is a specific, important, and early characteristic of type 2 diabetes. Diabetes Care (2011) 1.17

Effect of a 28-d treatment with L-796568, a novel beta(3)-adrenergic receptor agonist, on energy expenditure and body composition in obese men. Am J Clin Nutr (2002) 1.17

Glucose-dependent insulinotropic polypeptide may enhance fatty acid re-esterification in subcutaneous abdominal adipose tissue in lean humans. Diabetes (2010) 1.16

Altered skeletal muscle fiber composition and size precede whole-body insulin resistance in young men with low birth weight. J Clin Endocrinol Metab (2007) 1.16

Major increase in prevalence of overweight and obesity between 1987 and 2001 among Danish adults. Obes Res (2004) 1.14

Antidiabetic actions of endogenous and exogenous GLP-1 in type 1 diabetic patients with and without residual β-cell function. Diabetes (2011) 1.12

Differential effects of protein quality on postprandial lipemia in response to a fat-rich meal in type 2 diabetes: comparison of whey, casein, gluten, and cod protein. Am J Clin Nutr (2009) 1.12

Effect of dairy calcium or supplementary calcium intake on postprandial fat metabolism, appetite, and subsequent energy intake. Am J Clin Nutr (2007) 1.11

Increased expression of TNF-alpha, IL-6, and IL-8 in HALS: implications for reduced adiponectin expression and plasma levels. Am J Physiol Endocrinol Metab (2003) 1.11

Food intake is inhibited by oral oleoylethanolamide. J Lipid Res (2004) 1.11

Early differential defects of insulin secretion and action in 19-year-old caucasian men who had low birth weight. Diabetes (2002) 1.10

IRS-1 serine phosphorylation and insulin resistance in skeletal muscle from pancreas transplant recipients. Diabetes (2006) 1.10

Seasonal variation in objectively measured physical activity, sedentary time, cardio-respiratory fitness and sleep duration among 8-11 year-old Danish children: a repeated-measures study. BMC Public Health (2013) 1.10

Increased recovery rates of phosphocreatine and inorganic phosphate after isometric contraction in oxidative muscle fibers and elevated hepatic insulin resistance in homozygous carriers of the A-allele of FTO rs9939609. J Clin Endocrinol Metab (2008) 1.09

Effect on 24-h energy expenditure of a moderate-fat diet high in monounsaturated fatty acids compared with that of a low-fat, carbohydrate-rich diet: a 6-mo controlled dietary intervention trial. Am J Clin Nutr (2007) 1.09

[N-3 polyunsaturated acids and cardiovascular disease. Cochrane analysis with unclear conclusions]. Ugeskr Laeger (2005) 1.09

Reduced skeletal muscle mitochondrial respiration and improved glucose metabolism in nondiabetic obese women during a very low calorie dietary intervention leading to rapid weight loss. Metabolism (2009) 1.09

Contribution of gastroenteropancreatic appetite hormones to protein-induced satiety. Am J Clin Nutr (2013) 1.09

Dissociation between fat-induced in vivo insulin resistance and proximal insulin signaling in skeletal muscle in men at risk for type 2 diabetes. J Clin Endocrinol Metab (2004) 1.08

Pleiotropic effects of GIP on islet function involve osteopontin. Diabetes (2011) 1.08

The satiating power of protein--a key to obesity prevention? Am J Clin Nutr (2005) 1.08

Altered PI3-kinase/Akt signalling in skeletal muscle of young men with low birth weight. PLoS One (2008) 1.08

Guidelines for the New Nordic Diet. Public Health Nutr (2012) 1.08

Improved postprandial glycemic control with biphasic insulin aspart relative to biphasic insulin lispro and biphasic human insulin in patients with type 2 diabetes. Diabetes Care (2002) 1.07

Weight loss as treatment for knee osteoarthritis symptoms in obese patients: 1-year results from a randomised controlled trial. Ann Rheum Dis (2011) 1.07

Design of the OPUS School Meal Study: a randomised controlled trial assessing the impact of serving school meals based on the New Nordic Diet. Scand J Public Health (2012) 1.07

On the role of glucose-dependent insulintropic polypeptide in postprandial metabolism in humans. Am J Physiol Endocrinol Metab (2009) 1.06

Preserved inhibitory potency of GLP-1 on glucagon secretion in type 2 diabetes mellitus. J Clin Endocrinol Metab (2009) 1.06

Comparison of two physical activity questionnaires in obese subjects: the NUGENOB study. Med Sci Sports Exerc (2005) 1.06

C-reactive protein, insulin resistance and risk of cardiovascular disease: a population-based study. Eur J Cardiovasc Prev Rehabil (2008) 1.05

Ruminant and industrially produced trans fatty acids: health aspects. Food Nutr Res (2008) 1.05

The effect of protein and glycemic index on children's body composition: the DiOGenes randomized study. Pediatrics (2010) 1.05

Effect of dairy proteins on appetite, energy expenditure, body weight, and composition: a review of the evidence from controlled clinical trials. Adv Nutr (2013) 1.05