pncA gene expression and prediction factors on pyrazinamide resistance in Mycobacterium tuberculosis.

PubWeight™: 0.90‹?›

🔗 View Article (PMC 3755357)

Published in Tuberculosis (Edinb) on July 16, 2013

Authors

Patricia Sheen1, Katherine Lozano, Robert H Gilman, Hugo J Valencia, Sebastian Loli, Patricia Fuentes, Louis Grandjean, Mirko Zimic

Author Affiliations

1: Unidad de Bioinformática y Biología Molecular, Laboratorios de Investigación y Desarrollo, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Av. Honorio Delgado 430, SMP, Lima, Peru.

Articles cited by this

The growing burden of tuberculosis: global trends and interactions with the HIV epidemic. Arch Intern Med (2003) 24.99

Tuberculosis: commentary on a reemergent killer. Science (1992) 14.51

Simple pyrazinamidase and urease tests for routine identification of mycobacteria. Am Rev Respir Dis (1974) 7.40

Human catechol-O-methyltransferase haplotypes modulate protein expression by altering mRNA secondary structure. Science (2006) 6.71

Pyrazinamide susceptibility and amidase activity of tubercle bacilli. Am Rev Respir Dis (1967) 5.45

The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors. Nucleic Acids Res (1999) 4.74

The curious characteristics of pyrazinamide: a review. Int J Tuberc Lung Dis (2003) 4.48

Pyrazinamide inhibits trans-translation in Mycobacterium tuberculosis. Science (2011) 4.13

Characterization of pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis. Antimicrob Agents Chemother (1997) 3.75

The action of antituberculosis drugs in short-course chemotherapy. Tubercle (1985) 3.69

Mutations associated with pyrazinamide resistance in pncA of Mycobacterium tuberculosis complex organisms. Antimicrob Agents Chemother (1997) 3.46

Nicotinamide adenine dinucleotide biosynthesis and pyridine nucleotide cycle metabolism in microbial systems. Microbiol Rev (1980) 3.11

Role of acid pH and deficient efflux of pyrazinoic acid in unique susceptibility of Mycobacterium tuberculosis to pyrazinamide. J Bacteriol (1999) 2.47

Mode of action of pyrazinamide: disruption of Mycobacterium tuberculosis membrane transport and energetics by pyrazinoic acid. J Antimicrob Chemother (2003) 2.44

Mutation in pncA is a major mechanism of pyrazinamide resistance in Mycobacterium tuberculosis. Tuber Lung Dis (1997) 2.34

pncA mutations as a major mechanism of pyrazinamide resistance in Mycobacterium tuberculosis: spread of a monoresistant strain in Quebec, Canada. Antimicrob Agents Chemother (2000) 2.10

Expression of human telomerase subunits and correlation with telomerase activity in cervical cancer. Cancer Res (1998) 2.08

Pyrazinamidase activity of Mycobacterium tuberculosis--a test of sensitivity to pyrazinamide. Tubercle (1987) 1.75

Relationship between pyrazinamide resistance, loss of pyrazinamidase activity, and mutations in the pncA locus in multidrug-resistant clinical isolates of Mycobacterium tuberculosis. Antimicrob Agents Chemother (1999) 1.69

De novo biosynthesis of nicotinamide adenine dinucleotide in Escherichia coli: excretion of quinolinic acid by mutants lacking quinolinate phosphoribosyl transferase. J Bacteriol (1972) 1.51

The role of pyrazinamide in tuberculosis chemotherapy. Chest (1988) 1.48

Mechanisms of drug resistance in Mycobacterium tuberculosis. Front Biosci (2004) 1.39

Molecular characterization of pncA gene mutations in Mycobacterium tuberculosis clinical isolates from China. Epidemiol Infect (2000) 1.32

Effect of pyrazinamidase activity on pyrazinamide resistance in Mycobacterium tuberculosis. Tuberculosis (Edinb) (2009) 1.29

Reduced pyrazinamidase activity and the natural resistance of Mycobacterium kansasii to the antituberculosis drug pyrazinamide. Antimicrob Agents Chemother (1999) 1.16

Mitochondrial proliferation in the permanent vs. temporary cold: enzyme activities and mRNA levels in Antarctic and temperate zoarcid fish. Am J Physiol Regul Integr Comp Physiol (2003) 1.13

Drug resistance trends among previously treated tuberculosis patients in a national registry in Peru, 1994-2001. Int J Tuberc Lung Dis (2004) 1.09

pncA mutations in clinical Mycobacterium tuberculosis isolates from Korea. BMC Infect Dis (2001) 1.06

Pyrazinoic acid efflux rate in Mycobacterium tuberculosis is a better proxy of pyrazinamide resistance. Tuberculosis (Edinb) (2011) 1.05

Inhibition of nicotinamidase by nicotinamide adenine dinucleotide. J Biol Chem (1971) 0.99

Reduced messenger RNA expression level of p21 CIP1 in human colorectal carcinoma tissues and its association with p53 gene mutation. Int J Cancer (1996) 0.87

Molecular characterization of the Borrelia burgdorferi in vivo-essential protein PncA. Microbiology (2011) 0.85

A new approach for pyrazinamide susceptibility testing in Mycobacterium tuberculosis. Microb Drug Resist (2012) 0.84

Neural control of gene expression in skeletal muscle. Effects of chronic stimulation on lactate dehydrogenase isoenzymes and citrate synthase. Biochem J (1986) 0.79

Articles by these authors

Leptospirosis: a zoonotic disease of global importance. Lancet Infect Dis (2003) 15.02

Microscopic-observation drug-susceptibility assay for the diagnosis of TB. N Engl J Med (2006) 8.39

Taenia solium cysticercosis. Lancet (2003) 5.89

A trial of antiparasitic treatment to reduce the rate of seizures due to cerebral cysticercosis. N Engl J Med (2004) 5.75

Evaluation and treatment of chagas disease in the United States: a systematic review. JAMA (2007) 5.22

Human brucellosis. Lancet Infect Dis (2007) 4.92

Effects of stunting, diarrhoeal disease, and parasitic infection during infancy on cognition in late childhood: a follow-up study. Lancet (2002) 4.90

Multi-country analysis of the effects of diarrhoea on childhood stunting. Int J Epidemiol (2008) 4.46

Effect of water and sanitation on childhood health in a poor Peruvian peri-urban community. Lancet (2004) 4.36

Natural ventilation for the prevention of airborne contagion. PLoS Med (2007) 3.73

The effect of deforestation on the human-biting rate of Anopheles darlingi, the primary vector of Falciparum malaria in the Peruvian Amazon. Am J Trop Med Hyg (2006) 3.72

Prevention and control of cystic echinococcosis. Lancet Infect Dis (2007) 3.64

Current consensus guidelines for treatment of neurocysticercosis. Clin Microbiol Rev (2002) 3.37

Microscopic observation drug susceptibility assay, a rapid, reliable diagnostic test for multidrug-resistant tuberculosis suitable for use in resource-poor settings. J Clin Microbiol (2004) 3.27

Functional adaptation of BabA, the H. pylori ABO blood group antigen binding adhesin. Science (2004) 3.06

Perilesional brain oedema and seizure activity in patients with calcified neurocysticercosis: a prospective cohort and nested case-control study. Lancet Neurol (2008) 3.04

Clinical spectrum of pulmonary involvement in leptospirosis in a region of endemicity, with quantification of leptospiral burden. Clin Infect Dis (2005) 2.75

Diagnostic approaches for paediatric tuberculosis by use of different specimen types, culture methods, and PCR: a prospective case-control study. Lancet Infect Dis (2010) 2.69

Linking deforestation to malaria in the Amazon: characterization of the breeding habitat of the principal malaria vector, Anopheles darlingi. Am J Trop Med Hyg (2009) 2.64

Triosephosphate isomerase gene characterization and potential zoonotic transmission of Giardia duodenalis. Emerg Infect Dis (2003) 2.46

Endemic malaria in the Peruvian Amazon region of Iquitos. Am J Trop Med Hyg (2003) 2.43

Species identification after treatment for human taeniasis. Lancet (2004) 2.43

Multiple norovirus infections in a birth cohort in a Peruvian Periurban community. Clin Infect Dis (2013) 2.37

Influence of Leishmania (Viannia) species on the response to antimonial treatment in patients with American tegumentary leishmaniasis. J Infect Dis (2007) 2.33

The detection of airborne transmission of tuberculosis from HIV-infected patients, using an in vivo air sampling model. Clin Infect Dis (2007) 2.28

Prolonged infectiousness of tuberculosis patients in a directly observed therapy short-course program with standardized therapy. Clin Infect Dis (2010) 2.11

Neurocysticercosis: A natural human model of epileptogenesis. Epilepsia (2014) 2.11

New concepts in the diagnosis and management of neurocysticercosis (Taenia solium). Am J Trop Med Hyg (2005) 2.10

The infectiousness of tuberculosis patients coinfected with HIV. PLoS Med (2008) 2.08

Detection of Taenia solium antigens and anti-T. solium antibodies in paired serum and cerebrospinal fluid samples from patients with intraparenchymal or extraparenchymal neurocysticercosis. J Infect Dis (2009) 2.06

Tuberculosis mortality, drug resistance, and infectiousness in patients with and without HIV infection in Peru. Am J Trop Med Hyg (2006) 2.05

Can the power of mobile phones be used to improve tuberculosis diagnosis in developing countries? Trans R Soc Trop Med Hyg (2008) 2.01

Cryptosporidium species and subtypes and clinical manifestations in children, Peru. Emerg Infect Dis (2008) 1.96

Environmental exposure and leptospirosis, Peru. Emerg Infect Dis (2004) 1.96

Helicobacter pylori CagA phosphorylation-independent function in epithelial proliferation and inflammation. Cell Host Microbe (2009) 1.96

Determining risk for severe leptospirosis by molecular analysis of environmental surface waters for pathogenic Leptospira. PLoS Med (2006) 1.92

Effects of acute diarrhea on linear growth in Peruvian children. Am J Epidemiol (2003) 1.90

Human leptospirosis caused by a new, antigenically unique Leptospira associated with a Rattus species reservoir in the Peruvian Amazon. PLoS Negl Trop Dis (2008) 1.87

Periurban Trypanosoma cruzi-infected Triatoma infestans, Arequipa, Peru. Emerg Infect Dis (2006) 1.85

Congenital Trypanosoma cruzi transmission in Santa Cruz, Bolivia. Clin Infect Dis (2009) 1.81

Improved recovery of Mycobacterium tuberculosis from children using the microscopic observation drug susceptibility method. Pediatrics (2006) 1.74

Fecal contamination of drinking water within peri-urban households, Lima, Peru. Am J Trop Med Hyg (2007) 1.72

Epilepsy and neurocysticercosis in Atahualpa: a door-to-door survey in rural coastal Ecuador. Epilepsia (2005) 1.65

Upper-room ultraviolet light and negative air ionization to prevent tuberculosis transmission. PLoS Med (2009) 1.64

Transposable element ISHp608 of Helicobacter pylori: nonrandom geographic distribution, functional organization, and insertion specificity. J Bacteriol (2002) 1.60

Association between vitamin D receptor gene polymorphisms and response to treatment of pulmonary tuberculosis. J Infect Dis (2004) 1.60

Differences in cardiovascular risk factors in rural, urban and rural-to-urban migrants in Peru. Heart (2011) 1.60

Microscopic observation drug susceptibility assay for tuberculosis screening before isoniazid preventive therapy in HIV-infected persons. Clin Infect Dis (2010) 1.60

Diagnosis of sputum-scarce HIV-associated pulmonary tuberculosis in Lima, Peru. Lancet (2005) 1.57

Hyperendemic human and porcine Taenia solium infection in Perú. Am J Trop Med Hyg (2003) 1.56

Improved detection of Mycobacterium tuberculosis in Peruvian children by use of a heminested IS6110 polymerase chain reaction assay. Clin Infect Dis (2002) 1.56

Thyroid hormone levels improve the prediction of mortality among patients admitted to the intensive care unit. Intensive Care Med (2005) 1.55

Taenia solium cysticercosis hotspots surrounding tapeworm carriers: clustering on human seroprevalence but not on seizures. PLoS Negl Trop Dis (2009) 1.55

Swine cysticercosis hotspots surrounding Taenia solium tapeworm carriers. Am J Trop Med Hyg (2007) 1.54

Differences in clinical manifestations among Cryptosporidium species and subtypes in HIV-infected persons. J Infect Dis (2007) 1.53

Utility of a protein fraction with cathepsin L-Like activity purified from cysticercus fluid of Taenia solium in the diagnosis of human cysticercosis. Am J Trop Med Hyg (2009) 1.53

Addressing geographical variation in the progression of non-communicable diseases in Peru: the CRONICAS cohort study protocol. BMJ Open (2012) 1.52

Helicobacter Pylori's plasticity zones are novel transposable elements. PLoS One (2009) 1.48

Helicobacter pylori from Peruvian amerindians: traces of human migrations in strains from remote Amazon, and genome sequence of an Amerind strain. PLoS One (2010) 1.48

The effect on cardiovascular risk factors of migration from rural to urban areas in Peru: PERU MIGRANT Study. BMC Cardiovasc Disord (2009) 1.46

Lung ultrasound for the diagnosis of pneumonia in adults: a systematic review and meta-analysis. Respir Res (2014) 1.44

Epidemiologic differences between cyclosporiasis and cryptosporidiosis in Peruvian children. Emerg Infect Dis (2002) 1.43

Tetrazolium microplate assay as a rapid and inexpensive colorimetric method for determination of antibiotic susceptibility of Mycobacterium tuberculosis. J Clin Microbiol (2002) 1.43

Socio-demographics and the development of malaria elimination strategies in the low transmission setting. Acta Trop (2011) 1.43

Chagas disease transmission in periurban communities of Arequipa, Peru. Clin Infect Dis (2008) 1.40

Effects of nutritional status on diarrhea in Peruvian children. J Pediatr (2002) 1.39

Geographic variation in the sensitivity of recombinant antigen-based rapid tests for chronic Trypanosoma cruzi infection. Am J Trop Med Hyg (2009) 1.38

Human caliciviruses as a cause of severe gastroenteritis in Peruvian children. J Infect Dis (2004) 1.37

Identification of the cryptosporidium pig genotype in a human patient. J Infect Dis (2002) 1.36

Cryptosporidium species and genotypes in HIV-positive patients in Lima, Peru. J Eukaryot Microbiol (2003) 1.34

The epidemiology of intestinal microsporidiosis in patients with HIV/AIDS in Lima, Peru. J Infect Dis (2005) 1.33

Diversity of bat-associated Leptospira in the Peruvian Amazon inferred by bayesian phylogenetic analysis of 16S ribosomal DNA sequences. Am J Trop Med Hyg (2005) 1.33

Wasting is associated with stunting in early childhood. J Nutr (2012) 1.33

Vaccination of pigs to control human neurocysticercosis. Am J Trop Med Hyg (2005) 1.32

Unopposed matrix metalloproteinase-9 expression in human tuberculous granuloma and the role of TNF-alpha-dependent monocyte networks. J Immunol (2003) 1.30

Impregnated netting slows infestation by Triatoma infestans. Am J Trop Med Hyg (2008) 1.29

Multiantigen print immunoassay for comparison of diagnostic antigens for Taenia solium cysticercosis and taeniasis. Clin Vaccine Immunol (2009) 1.29

Effect of pyrazinamidase activity on pyrazinamide resistance in Mycobacterium tuberculosis. Tuberculosis (Edinb) (2009) 1.29

Seroepidemiology of strongyloidiasis in the Peruvian Amazon. Am J Trop Med Hyg (2006) 1.28

Characterization and cloning of T24, a Taenia solium antigen diagnostic for cysticercosis. Mol Biochem Parasitol (2006) 1.28

Cluster of type IV secretion genes in Helicobacter pylori's plasticity zone. J Bacteriol (2003) 1.26

Targeted screening strategies to detect Trypanosoma cruzi infection in children. PLoS Negl Trop Dis (2007) 1.26

Infrequent MODS TB culture cross-contamination in a high-burden resource-poor setting. Diagn Microbiol Infect Dis (2006) 1.26

Lack of an adverse effect of Giardia intestinalis infection on the health of Peruvian children. Am J Epidemiol (2008) 1.24

Systems biology approach predicts antibody signature associated with Brucella melitensis infection in humans. J Proteome Res (2011) 1.24

Diagnosis of cystic echinococcosis, central Peruvian Highlands. Emerg Infect Dis (2008) 1.23

Diarrhea in early childhood: short-term association with weight and long-term association with length. Am J Epidemiol (2013) 1.22

Evaluation of brucellosis by PCR and persistence after treatment in patients returning to the hospital for follow-up. Am J Trop Med Hyg (2007) 1.22

Helicobacter pylori reinfection is common in Peruvian adults after antibiotic eradication therapy. J Infect Dis (2003) 1.21

A worldwide analysis of beta-defensin copy number variation suggests recent selection of a high-expressing DEFB103 gene copy in East Asia. Hum Mutat (2011) 1.21

Effect of urbanisation on asthma, allergy and airways inflammation in a developing country setting. Thorax (2011) 1.20

Genetic diversity and transmission characteristics of Beijing family strains of Mycobacterium tuberculosis in Peru. PLoS One (2012) 1.20

Polymerase chain reaction and molecular genotyping to monitor parasitological response to anti-malarial chemotherapy in the Peruvian Amazon. Am J Trop Med Hyg (2006) 1.20

Polymerase chain reaction detection of Plasmodium vivax and Plasmodium falciparum DNA from stored serum samples: implications for retrospective diagnosis of malaria. Am J Trop Med Hyg (2007) 1.18

Comparative effects of vivax malaria, fever and diarrhoea on child growth. Int J Epidemiol (2012) 1.17

Outbreak of cyclosporiasis at a naval base in Lima, Peru. Am J Trop Med Hyg (2006) 1.17