Published in Infect Immun on July 22, 2013
B. anthracis associated cardiovascular dysfunction and shock: the potential contribution of both non-toxin and toxin components. BMC Med (2013) 0.85
Reverse-Phase Microarray Analysis Reveals Novel Targets in Lymph Nodes of Bacillus anthracis Spore-Challenged Mice. PLoS One (2015) 0.79
Exposure to Bacillus anthracis capsule results in suppression of human monocyte-derived dendritic cells. Infect Immun (2014) 0.77
Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells. Proc Natl Acad Sci U S A (1982) 10.36
Identification of the cellular receptor for anthrax toxin. Nature (2001) 8.78
Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor. Proc Natl Acad Sci U S A (2003) 5.95
Observations on experimental anthrax; demonstration of a specific lethal factor produced in vivo by Bacillus anthracis. Nature (1954) 4.56
Impairment of dendritic cells and adaptive immunity by anthrax lethal toxin. Nature (2003) 2.83
Construction and characterization of a protective antigen-deficient Bacillus anthracis strain. Mol Microbiol (1990) 2.67
Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition. EMBO Rep (2004) 2.64
Fatal inhalational anthrax with unknown source of exposure in a 61-year-old woman in New York City. JAMA (2002) 2.46
Pathology and pathogenesis of bioterrorism-related inhalational anthrax. Am J Pathol (2003) 2.11
Murine macrophages kill the vegetative form of Bacillus anthracis. Infect Immun (2005) 1.91
Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome. PLoS Pathog (2012) 1.90
Anthrax toxins suppress T lymphocyte activation by disrupting antigen receptor signaling. J Exp Med (2005) 1.90
Macrophage-derived cell lines do not express proinflammatory cytokines after exposure to Bacillus anthracis lethal toxin. Infect Immun (2001) 1.60
Detection of anthrax toxin in the serum of animals infected with Bacillus anthracis by using engineered immunoassays. Clin Vaccine Immunol (2006) 1.50
Human neutrophils kill Bacillus anthracis. PLoS Pathog (2005) 1.38
Anthrax lethal toxin paralyzes neutrophil actin-based motility. J Infect Dis (2005) 1.32
Receptors of anthrax toxin and cell entry. Mol Aspects Med (2009) 1.18
Anthrax toxins inhibit immune cell chemotaxis by perturbing chemokine receptor signalling. Cell Microbiol (2006) 1.15
Anthrax lethal toxin blocks MAPK kinase-dependent IL-2 production in CD4+ T cells. J Immunol (2005) 1.11
Observations on the cause of death in experimental anthrax. Lancet (1954) 1.10
Inhibition of mitogen-activated protein kinase signalling by Bacillus anthracis lethal toxin causes destabilization of interleukin-8 mRNA. Cell Microbiol (2006) 1.07
Bacillus anthracis peptidoglycan stimulates an inflammatory response in monocytes through the p38 mitogen-activated protein kinase pathway. PLoS One (2008) 1.07
Anthrax lethal toxin impairs IL-8 expression in epithelial cells through inhibition of histone H3 modification. PLoS Pathog (2009) 1.04
Interferon-inducible CXC chemokines directly contribute to host defense against inhalational anthrax in a murine model of infection. PLoS Pathog (2010) 1.03
Bacillus anthracis lethal toxin disrupts TCR signaling in CD1d-restricted NKT cells leading to functional anergy. PLoS Pathog (2009) 1.02
Anthrax lethal factor and edema factor act on conserved targets in Drosophila. Proc Natl Acad Sci U S A (2006) 1.00
Inflammatory cytokine response to Bacillus anthracis peptidoglycan requires phagocytosis and lysosomal trafficking. Infect Immun (2010) 0.99
Antimicrobial effects of interferon-inducible CXC chemokines against Bacillus anthracis spores and bacilli. Infect Immun (2009) 0.98
Identification of the bacterial protein FtsX as a unique target of chemokine-mediated antimicrobial activity against Bacillus anthracis. Proc Natl Acad Sci U S A (2011) 0.95
Human transferrin confers serum resistance against Bacillus anthracis. J Biol Chem (2010) 0.90
Cutting edge: primary innate immune cells respond efficiently to polymeric peptidoglycan, but not to peptidoglycan monomers. J Immunol (2011) 0.89
Antimicrobial activities of chemokines: not just a side-effect? Front Immunol (2012) 0.86
Anthrax lethal toxin suppresses chemokine production in human neutrophil NB-4 cells. Biochem Biophys Res Commun (2008) 0.84
Both lethal and edema toxins of Bacillus anthracis disrupt the human dendritic cell chemokine network. PLoS One (2012) 0.79
Clostridium difficile toxins: mechanism of action and role in disease. Clin Microbiol Rev (2005) 5.69
A fully integrated microfluidic genetic analysis system with sample-in-answer-out capability. Proc Natl Acad Sci U S A (2006) 3.03
E-selectin engages PSGL-1 and CD44 through a common signaling pathway to induce integrin alphaLbeta2-mediated slow leukocyte rolling. Blood (2010) 2.24
The role of circulating mesenchymal progenitor cells (fibrocytes) in the pathogenesis of pulmonary fibrosis. J Leukoc Biol (2009) 1.76
TREM2- and DAP12-dependent activation of PI3K requires DAP10 and is inhibited by SHIP1. Sci Signal (2010) 1.61
Mapping dominant-negative mutations of anthrax protective antigen by scanning mutagenesis. Proc Natl Acad Sci U S A (2003) 1.59
CD95 rapidly clusters in cells of diverse origins. Cancer Biol Ther (2003) 1.50
Identification of Clostridium difficile toxin B cardiotoxicity using a zebrafish embryo model of intoxication. Proc Natl Acad Sci U S A (2006) 1.35
Activation of nuclear factor of activated T cells by human T-lymphotropic virus type 1 accessory protein p12(I). J Virol (2002) 1.27
Variations in TcdB activity and the hypervirulence of emerging strains of Clostridium difficile. PLoS Pathog (2010) 1.26
Clostridium difficile toxin B activates dual caspase-dependent and caspase-independent apoptosis in intoxicated cells. Cell Microbiol (2002) 1.25
Bacillus anthracis oedema toxin as a cause of tissue necrosis and cell type-specific cytotoxicity. Cell Microbiol (2005) 1.25
Early NK cell-derived IFN-{gamma} is essential to host defense in neutropenic invasive aspergillosis. J Immunol (2009) 1.22
Innate immune response to H3N2 and H1N1 influenza virus infection in a human lung organ culture model. Virology (2009) 1.19
Clostridium difficile infection. Am J Med Sci (2010) 1.17
Interleukin-6 aborts lymphopoiesis and elevates production of myeloid cells in systemic lupus erythematosus-prone B6.Sle1.Yaa animals. Blood (2009) 1.17
IL-6 blocks a discrete early step in lymphopoiesis. Blood (2005) 1.14
Biomarker identification in human pancreatic cancer sera. Pancreas (2008) 1.13
A method adapting microarray technology for signature-tagged mutagenesis of Desulfovibrio desulfuricans G20 and Shewanella oneidensis MR-1 in anaerobic sediment survival experiments. Appl Environ Microbiol (2005) 1.12
Dynamics of the STAT3 transcription factor: nuclear import dependent on Ran and importin-β1. PLoS One (2011) 1.11
Effects of endogenous D-alanine synthesis and autoinhibition of Bacillus anthracis germination on in vitro and in vivo infections. Infect Immun (2007) 1.11
Vav activation and function as a rac guanine nucleotide exchange factor in macrophage colony-stimulating factor-induced macrophage chemotaxis. Mol Cell Biol (2005) 1.10
Bacillus anthracis spores stimulate cytokine and chemokine innate immune responses in human alveolar macrophages through multiple mitogen-activated protein kinase pathways. Infect Immun (2006) 1.08
Clostridium difficile 027/BI/NAP1 encodes a hypertoxic and antigenically variable form of TcdB. PLoS Pathog (2013) 1.08
Inhibition of Bacillus anthracis spore outgrowth by nisin. Antimicrob Agents Chemother (2008) 1.08
Human lung innate immune response to Bacillus anthracis spore infection. Infect Immun (2007) 1.08
Bacillus anthracis peptidoglycan stimulates an inflammatory response in monocytes through the p38 mitogen-activated protein kinase pathway. PLoS One (2008) 1.07
Src homology 2-containing 5-inositol phosphatase (SHIP) suppresses an early stage of lymphoid cell development through elevated interleukin-6 production by myeloid cells in bone marrow. J Exp Med (2004) 1.06
B cell antigen receptor endocytosis and antigen presentation to T cells require Vav and dynamin. J Biol Chem (2009) 1.06
Interferon-inducible CXC chemokines directly contribute to host defense against inhalational anthrax in a murine model of infection. PLoS Pathog (2010) 1.03
Bacillus anthracis lethal toxin disrupts TCR signaling in CD1d-restricted NKT cells leading to functional anergy. PLoS Pathog (2009) 1.02
Sequential B-cell epitopes of Bacillus anthracis lethal factor bind lethal toxin-neutralizing antibodies. Infect Immun (2008) 1.01
Select human anthrax protective antigen epitope-specific antibodies provide protection from lethal toxin challenge. J Infect Dis (2010) 1.01
Toxin-induced resistance in Bacillus anthracis lethal toxin-treated macrophages. Proc Natl Acad Sci U S A (2003) 1.00
CD1d-dependent B-cell help by NK-like T cells leads to enhanced and sustained production of Bacillus anthracis lethal toxin-neutralizing antibodies. Infect Immun (2010) 1.00
Cytotoxic activity of Bacillus anthracis protective antigen observed in a macrophage cell line overexpressing ANTXR1. Cell Microbiol (2006) 0.99
The major neutralizing antibody responses to recombinant anthrax lethal and edema factors are directed to non-cross-reactive epitopes. Infect Immun (2009) 0.99
Anthrax vaccination induced anti-lethal factor IgG: fine specificity and neutralizing capacity. Vaccine (2011) 0.99
Variations in virulence and molecular biology among emerging strains of Clostridium difficile. Microbiol Mol Biol Rev (2013) 0.99
Inflammatory cytokine response to Bacillus anthracis peptidoglycan requires phagocytosis and lysosomal trafficking. Infect Immun (2010) 0.99
Antimicrobial effects of interferon-inducible CXC chemokines against Bacillus anthracis spores and bacilli. Infect Immun (2009) 0.98
Variations in lethal toxin and cholesterol-dependent cytolysin production correspond to differences in cytotoxicity among strains of Clostridium sordellii. FEMS Microbiol Lett (2006) 0.98
C-reactive protein induces signaling through Fc gamma RIIa on HL-60 granulocytes. J Immunol (2002) 0.98
Convergence of signaling pathways on the activation of ERK in B cells. J Biol Chem (2002) 0.98
Desulfovibrio sp. genes involved in the respiration of sulfate during metabolism of hydrogen and lactate. Appl Environ Microbiol (2002) 0.96
Clostridium sordellii toxic shock syndrome. Lancet Infect Dis (2009) 0.96
Medical microbiology: A toxin contest. Nature (2010) 0.95
IL-6 increases B-cell IgG production in a feed-forward proinflammatory mechanism to skew hematopoiesis and elevate myeloid production. Blood (2010) 0.95
Identification of the bacterial protein FtsX as a unique target of chemokine-mediated antimicrobial activity against Bacillus anthracis. Proc Natl Acad Sci U S A (2011) 0.95
Nod1/Nod2-mediated recognition plays a critical role in induction of adaptive immunity to anthrax after aerosol exposure. Infect Immun (2009) 0.95
Regulatory interactions of a virulence-associated serine/threonine phosphatase-kinase pair in Bacillus anthracis. J Bacteriol (2009) 0.95
TcdB from hypervirulent Clostridium difficile exhibits increased efficiency of autoprocessing. Mol Microbiol (2012) 0.93
Loss of SHIP and CIS recruitment to the granulocyte colony-stimulating factor receptor contribute to hyperproliferative responses in severe congenital neutropenia/acute myelogenous leukemia. J Immunol (2004) 0.93
Gene expression profiling of human alveolar macrophages infected by B. anthracis spores demonstrates TNF-alpha and NF-kappab are key components of the innate immune response to the pathogen. BMC Infect Dis (2009) 0.93
Functional comparison of the two Bacillus anthracis glutamate racemases. J Bacteriol (2007) 0.92
Decreased glycogen synthase kinase 3-beta levels and related physiological changes in Bacillus anthracis lethal toxin-treated macrophages. Cell Microbiol (2003) 0.92
Anti-peptidoglycan antibodies and Fcγ receptors are the key mediators of inflammation in Gram-positive sepsis. J Immunol (2012) 0.92
Regulation of anthrax toxin-specific antibody titers by natural killer T cell-derived IL-4 and IFNγ. PLoS One (2011) 0.91
Glycogen synthase kinase 3 activation is important for anthrax edema toxin-induced dendritic cell maturation and anthrax toxin receptor 2 expression in macrophages. Infect Immun (2011) 0.90
Vav and Rac activation in B cell antigen receptor endocytosis involves Vav recruitment to the adapter protein LAB. J Biol Chem (2009) 0.90
Resistance of human alveolar macrophages to Bacillus anthracis lethal toxin. J Immunol (2009) 0.90
Cutting edge: primary innate immune cells respond efficiently to polymeric peptidoglycan, but not to peptidoglycan monomers. J Immunol (2011) 0.89
Increased cAMP in monocytes augments Notch signaling mechanisms by elevating RBP-J and transducin-like enhancer of Split (TLE). J Biol Chem (2013) 0.89
Retromer guides STxB and CD8-M6PR from early to recycling endosomes, EHD1 guides STxB from recycling endosome to Golgi. Traffic (2012) 0.88
Human lung innate immune cytokine response to adenovirus type 7. J Gen Virol (2010) 0.88
High-throughput, single-cell analysis of macrophage interactions with fluorescently labeled Bacillus anthracis spores. Appl Environ Microbiol (2008) 0.87
Genes that enhance the ecological fitness of Shewanella oneidensis MR-1 in sediments reveal the value of antibiotic resistance. Appl Environ Microbiol (2006) 0.87
Mutational analysis of the enzymatic domain of Clostridium difficile toxin B reveals novel inhibitors of the wild-type toxin. Infect Immun (2003) 0.86
Identification of genes that confer sediment fitness to Desulfovibrio desulfuricans G20. Appl Environ Microbiol (2007) 0.85
Bacillus anthracis edema toxin activates nuclear glycogen synthase kinase 3beta. Infect Immun (2008) 0.85
Adaptor protein SLAT modulates Fcgamma receptor-mediated phagocytosis in murine macrophages. J Biol Chem (2009) 0.84
Calcium-dependent viral internalization is required for adenovirus type 7 induction of IL-8 protein. Virology (2006) 0.83
The mechanism of Bacillus anthracis intracellular germination requires multiple and highly diverse genetic loci. Infect Immun (2008) 0.83
Ca2+ chemotaxis in Dictyostelium discoideum. J Cell Sci (2010) 0.83
Bacillus anthracis peptidoglycan activates human platelets through FcγRII and complement. Blood (2013) 0.82
Interleukin-6 deficiency corrects nephritis, lymphocyte abnormalities, and secondary Sjögren's syndrome features in lupus-prone Sle1.Yaa mice. Arthritis Rheumatol (2014) 0.82
Clostridium sordellii lethal toxin is maintained in a multimeric protein complex. Infect Immun (2004) 0.82
Evidence for chimeric sequences formed during random arbitrarily primed PCR. J Microbiol Methods (2003) 0.80
MAP kinases have different functions in Dictyostelium G protein-mediated signaling. Cell Signal (2010) 0.79
Elucidating the in vivo targets of bacterial toxins. Future Microbiol (2007) 0.79
Adenomatous polyposis coli protein associates with C/EBP beta and increases Bacillus anthracis edema toxin-stimulated gene expression in macrophages. J Biol Chem (2011) 0.79
Human SAP is a novel peptidoglycan recognition protein that induces complement-independent phagocytosis of Staphylococcus aureus. J Immunol (2013) 0.78
Differential expression of Desulfovibrio vulgaris genes in response to Cu(II) and Hg(II) toxicity. Appl Environ Microbiol (2004) 0.78
A unique CD72 epitope suggests a potential interaction with Fc gamma RII/CD32 on B lineage lymphocytes. Hybridoma (Larchmt) (2006) 0.77
Autoregulatory characteristics of a Bacillus anthracis serine/threonine kinase. J Bacteriol (2011) 0.77
Critical intermediate steps in Clostridium sordellii lethal toxin-induced apoptosis. Biochem Biophys Res Commun (2007) 0.76
Systemic molecular and cellular changes induced in rats upon inhalation of JP-8 petroleum fuel vapor. Toxicol Mech Methods (2010) 0.76
Barriers to Implementation of Optimal Laboratory Biosafety Practices in Pakistan. Health Secur (2016) 0.75
Determination of serum antibodies to Clostridium difficile toxin B in patients with inflammatory bowel disease. Gastroenterol Hepatol (N Y) (2012) 0.75
Serum amyloid A protects murine macrophages from lethal toxin-mediated death. Cell Immunol (2011) 0.75
Differential inflammatory responses triggered by toxic small molecules. Environ Sci Pollut Res Int (2011) 0.75