Clostridium difficile toxins: mechanism of action and role in disease.

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Published in Clin Microbiol Rev on April 01, 2005

Authors

Daniel E Voth1, Jimmy D Ballard

Author Affiliations

1: Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.

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Mutational analysis of the enzymatic domain of Clostridium difficile toxin B reveals novel inhibitors of the wild-type toxin. Infect Immun (2003) 0.86

Identification of genes that confer sediment fitness to Desulfovibrio desulfuricans G20. Appl Environ Microbiol (2007) 0.85

Bacillus anthracis edema toxin activates nuclear glycogen synthase kinase 3beta. Infect Immun (2008) 0.85

The mechanism of Bacillus anthracis intracellular germination requires multiple and highly diverse genetic loci. Infect Immun (2008) 0.83

Clostridium sordellii lethal toxin is maintained in a multimeric protein complex. Infect Immun (2004) 0.82

Evidence for chimeric sequences formed during random arbitrarily primed PCR. J Microbiol Methods (2003) 0.80

Elucidating the in vivo targets of bacterial toxins. Future Microbiol (2007) 0.79

Adenomatous polyposis coli protein associates with C/EBP beta and increases Bacillus anthracis edema toxin-stimulated gene expression in macrophages. J Biol Chem (2011) 0.79

Toxin inhibition of antimicrobial factors induced by Bacillus anthracis peptidoglycan in human blood. Infect Immun (2013) 0.78

Differential expression of Desulfovibrio vulgaris genes in response to Cu(II) and Hg(II) toxicity. Appl Environ Microbiol (2004) 0.78

Autoregulatory characteristics of a Bacillus anthracis serine/threonine kinase. J Bacteriol (2011) 0.77

Critical intermediate steps in Clostridium sordellii lethal toxin-induced apoptosis. Biochem Biophys Res Commun (2007) 0.76

Determination of serum antibodies to Clostridium difficile toxin B in patients with inflammatory bowel disease. Gastroenterol Hepatol (N Y) (2012) 0.75

Serum amyloid A protects murine macrophages from lethal toxin-mediated death. Cell Immunol (2011) 0.75

Differential inflammatory responses triggered by toxic small molecules. Environ Sci Pollut Res Int (2011) 0.75