Published in AIDS on June 19, 2013
HIV treatments reduce malaria liver stage burden in a non-human primate model of malaria infection at clinically relevant concentrations in vivo. PLoS One (2014) 0.84
Neither the HIV protease inhibitor lopinavir-ritonavir nor the antimicrobial trimethoprim-sulfamethoxazole prevent malaria relapse in plasmodium cynomolgi-infected non-human primates. PLoS One (2014) 0.75
Effect of antiretroviral therapy on malaria incidence in HIV-infected Ugandan adults. AIDS (2017) 0.75
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Inhibition of Plasmodium Hepatic Infection by Antiretroviral Compounds. Front Cell Infect Microbiol (2017) 0.75
Antiretrovirals as antimalarial agents. J Infect Dis (2004) 3.60
Demonstration of heat-shock protein 70 in the sporozoite stage of malaria parasites. Parasitol Res (1994) 2.65
Establishment of a human hepatocyte line that supports in vitro development of the exo-erythrocytic stages of the malaria parasites Plasmodium falciparum and P. vivax. Am J Trop Med Hyg (2006) 2.39
Consequences of HIV infection on malaria and therapeutic implications: a systematic review. Lancet Infect Dis (2011) 2.01
Antimalarial activity of human immunodeficiency virus type 1 protease inhibitors. Antimicrob Agents Chemother (2005) 2.00
Preerythrocytic, live-attenuated Plasmodium falciparum vaccine candidates by design. Proc Natl Acad Sci U S A (2009) 1.72
Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria. Antimicrob Agents Chemother (2006) 1.72
Simple centrifugation method for rapid separation of sporozoites from mosquitoes. J Parasitol (1984) 1.62
Antiretroviral agents and prevention of malaria in HIV-infected Ugandan children. N Engl J Med (2012) 1.58
HIV protease inhibitors inhibit the development of preerythrocytic-stage plasmodium parasites. J Infect Dis (2009) 1.24
A long and winding road: the Plasmodium sporozoite's journey in the mammalian host. Parasitol Int (2007) 1.18
In vitro activity of antiretroviral drugs against Plasmodium falciparum. Antimicrob Agents Chemother (2011) 1.16
Antimalarial effects of human immunodeficiency virus type 1 protease inhibitors differ from those of the aspartic protease inhibitor pepstatin. Antimicrob Agents Chemother (2006) 1.06
Antimalarial asexual stage-specific and gametocytocidal activities of HIV protease inhibitors. Antimicrob Agents Chemother (2009) 1.01
HIV treatments have malaria gametocyte killing and transmission blocking activity. J Infect Dis (2013) 0.99
HIV nonnucleoside reverse transcriptase inhibitors and trimethoprim-sulfamethoxazole inhibit plasmodium liver stages. J Infect Dis (2012) 0.96
Molecular and functional characterization of drug-metabolizing enzymes and transporter expression in the novel spontaneously immortalized human hepatocyte line HC-04. Toxicol In Vitro (2007) 0.94
The activity and inhibition of the food vacuole plasmepsin from the rodent malaria parasite Plasmodium chabaudi. Acta Trop (2005) 0.93
Prevalence of asymptomatic parasitemia and gametocytemia among HIV-infected Ugandan children randomized to receive different antiretroviral therapies. Am J Trop Med Hyg (2013) 0.91
Discovery of gene function by expression profiling of the malaria parasite life cycle. Science (2003) 10.57
Randomized, double-blind, phase 2a trial of falciparum malaria vaccines RTS,S/AS01B and RTS,S/AS02A in malaria-naive adults: safety, efficacy, and immunologic associates of protection. J Infect Dis (2009) 6.90
Malaria: progress, perils, and prospects for eradication. J Clin Invest (2008) 6.54
Neonatal-onset multisystem inflammatory disease responsive to interleukin-1beta inhibition. N Engl J Med (2006) 6.17
Malaria in pregnancy: pathogenesis and immunity. Lancet Infect Dis (2007) 3.88
Iron deficiency protects against severe Plasmodium falciparum malaria and death in young children. Clin Infect Dis (2012) 3.69
The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites. Cell Host Microbe (2008) 2.98
Cutaneous anthrax associated with microangiopathic hemolytic anemia and coagulopathy in a 7-month-old infant. JAMA (2002) 2.93
Decreased susceptibility to Plasmodium falciparum infection in pregnant women with iron deficiency. J Infect Dis (2008) 2.82
Maternal malaria and gravidity interact to modify infant susceptibility to malaria. PLoS Med (2005) 2.72
Protective immunity induced with malaria vaccine, RTS,S, is linked to Plasmodium falciparum circumsporozoite protein-specific CD4+ and CD8+ T cells producing IFN-gamma. J Immunol (2003) 2.71
Heparan sulfate proteoglycans provide a signal to Plasmodium sporozoites to stop migrating and productively invade host cells. Cell Host Microbe (2007) 2.64
Intermittent treatment to prevent pregnancy malaria does not confer benefit in an area of widespread drug resistance. Clin Infect Dis (2011) 2.56
Phase 1/2a study of the malaria vaccine candidate apical membrane antigen-1 (AMA-1) administered in adjuvant system AS01B or AS02A. PLoS One (2009) 2.49
The hospital water supply as a source of nosocomial infections: a plea for action. Arch Intern Med (2002) 2.48
Quantitative dynamics of Plasmodium yoelii sporozoite transmission by infected anopheline mosquitoes. Infect Immun (2005) 2.29
Towards an RTS,S-based, multi-stage, multi-antigen vaccine against falciparum malaria: progress at the Walter Reed Army Institute of Research. Vaccine (2005) 2.18
Parasite burden and severity of malaria in Tanzanian children. N Engl J Med (2014) 2.07
Long-term effects of protease-inhibitor-based combination therapy on CD4 T-cell recovery in HIV-1-infected children and adolescents. Lancet (2003) 2.04
Plasmodium sporozoites trickle out of the injection site. Cell Microbiol (2007) 1.98
Immunogenicity, immunologic memory, and safety following measles revaccination in HIV-infected children receiving highly active antiretroviral therapy. J Infect Dis (2012) 1.98
The Plasmodium circumsporozoite protein is proteolytically processed during cell invasion. J Exp Med (2005) 1.85
Pirfenidone slows renal function decline in patients with focal segmental glomerulosclerosis. Clin J Am Soc Nephrol (2007) 1.80
A novel histological grading scheme for placental malaria applied in areas of high and low malaria transmission. J Infect Dis (2010) 1.79
Genetically attenuated Plasmodium berghei liver stages induce sterile protracted protection that is mediated by major histocompatibility complex Class I-dependent interferon-gamma-producing CD8+ T cells. J Infect Dis (2007) 1.79
Pharmacokinetics and safety of oral posaconazole in neutropenic stem cell transplant recipients. Antimicrob Agents Chemother (2006) 1.75
Preerythrocytic, live-attenuated Plasmodium falciparum vaccine candidates by design. Proc Natl Acad Sci U S A (2009) 1.72
Phase 2a trial of 0, 1, and 3 month and 0, 7, and 28 day immunization schedules of malaria vaccine RTS,S/AS02 in malaria-naïve adults at the Walter Reed Army Institute of Research. Vaccine (2008) 1.71
Phase I safety and immunogenicity trial of FMP1/AS02A, a Plasmodium falciparum MSP-1 asexual blood stage vaccine. Vaccine (2005) 1.68
The CXCR4 antagonist plerixafor corrects panleukopenia in patients with WHIM syndrome. Blood (2011) 1.65
Attenuated Plasmodium yoelii lacking purine nucleoside phosphorylase confer protective immunity. Nat Med (2008) 1.65
The malaria circumsporozoite protein has two functional domains, each with distinct roles as sporozoites journey from mosquito to mammalian host. J Exp Med (2011) 1.62
Protracted protection to Plasmodium berghei malaria is linked to functionally and phenotypically heterogeneous liver memory CD8+ T cells. J Immunol (2003) 1.60
Immunological memory after exposure to variola virus, monkeypox virus, and vaccinia virus. J Infect Dis (2007) 1.59
Hypertension and maternal-fetal conflict during placental malaria. PLoS Med (2006) 1.56
Real-time quantitative reverse transcription PCR for monitoring of blood-stage Plasmodium falciparum infections in malaria human challenge trials. Am J Trop Med Hyg (2012) 1.55
Vaccination with live Plasmodium yoelii blood stage parasites under chloroquine cover induces cross-stage immunity against malaria liver stage. J Immunol (2008) 1.53
Susceptibility of human Th17 cells to human immunodeficiency virus and their perturbation during infection. J Infect Dis (2010) 1.52
Implementation of HIV testing at 2 New York City bathhouses: from pilot to clinical service. Clin Infect Dis (2009) 1.46
Plasmodium falciparum: chondroitin sulfate A is the major receptor for adhesion of parasitized erythrocytes in the placenta. Exp Parasitol (2006) 1.44
Malaria in India: the center for the study of complex malaria in India. Acta Trop (2011) 1.42
Sterile protection against malaria is independent of immune responses to the circumsporozoite protein. PLoS One (2007) 1.41
Reduced cord blood immune effector-cell responsiveness mediated by CD4+ cells induced in utero as a consequence of placental Plasmodium falciparum infection. J Infect Dis (2005) 1.40
Maternal peripheral blood level of IL-10 as a marker for inflammatory placental malaria. Malar J (2008) 1.37
Ritonavir-based highly active antiretroviral therapy in human immunodeficiency virus type 1-infected infants younger than 24 months of age. Pediatr Infect Dis J (2005) 1.34
Immunogenicity, safety, and predictors of response after a pneumococcal conjugate and pneumococcal polysaccharide vaccine series in human immunodeficiency virus-infected children receiving highly active antiretroviral therapy. Pediatr Infect Dis J (2006) 1.32
Markers of endothelial dysfunction, coagulation and tissue fibrosis independently predict venous thromboembolism in HIV. AIDS (2011) 1.30
Evidence for globally shared, cross-reacting polymorphic epitopes in the pregnancy-associated malaria vaccine candidate VAR2CSA. Infect Immun (2008) 1.29
Noninvasive real-time monitoring of liver-stage development of bioluminescent Plasmodium parasites. J Infect Dis (2009) 1.28
Opsonization by antigen-specific antibodies as a mechanism of protective immunity induced by Plasmodium falciparum circumsporozoite protein-based vaccine. Parasite Immunol (2003) 1.28
Dendritic cells and hepatocytes use distinct pathways to process protective antigen from plasmodium in vivo. PLoS Pathog (2011) 1.27
Immunization with pre-erythrocytic antigen CelTOS from Plasmodium falciparum elicits cross-species protection against heterologous challenge with Plasmodium berghei. PLoS One (2010) 1.24
HIV protease inhibitors inhibit the development of preerythrocytic-stage plasmodium parasites. J Infect Dis (2009) 1.24
Factors associated with insulin resistance among children and adolescents perinatally infected with HIV-1 in the pediatric HIV/AIDS cohort study. Horm Res Paediatr (2011) 1.23
VAR2CSA domains expressed in Escherichia coli induce cross-reactive antibodies to native protein. J Infect Dis (2008) 1.20
The distinct proteome of placental malaria parasites. Mol Biochem Parasitol (2007) 1.19
Hierarchical, domain type-specific acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 in Tanzanian children. Infect Immun (2010) 1.19
Total and putative surface proteomics of malaria parasite salivary gland sporozoites. Mol Cell Proteomics (2013) 1.19
Genome-wide expression analysis of placental malaria reveals features of lymphoid neogenesis during chronic infection. J Immunol (2007) 1.18
Two DBLgamma subtypes are commonly expressed by placental isolates of Plasmodium falciparum. Mol Biochem Parasitol (2002) 1.18
Effects of sex, parity, and sequence variation on seroreactivity to candidate pregnancy malaria vaccine antigens. J Infect Dis (2007) 1.18
Immunization with VAR2CSA-DBL5 recombinant protein elicits broadly cross-reactive antibodies to placental Plasmodium falciparum-infected erythrocytes. Infect Immun (2010) 1.18
The Plasmodium TRAP/MIC2 family member, TRAP-Like Protein (TLP), is involved in tissue traversal by sporozoites. Cell Microbiol (2008) 1.17
Shedding of TRAP by a rhomboid protease from the malaria sporozoite surface is essential for gliding motility and sporozoite infectivity. PLoS Pathog (2012) 1.16
Platelet factor 4 activity against P. falciparum and its translation to nonpeptidic mimics as antimalarials. Cell Host Microbe (2012) 1.16
First-in-human evaluation of genetically attenuated Plasmodium falciparum sporozoites administered by bite of Anopheles mosquitoes to adult volunteers. Vaccine (2013) 1.16
Protective immunity induced with the RTS,S/AS vaccine is associated with IL-2 and TNF-α producing effector and central memory CD4 T cells. PLoS One (2011) 1.15
Antimalarial activity of allicin, a biologically active compound from garlic cloves. Antimicrob Agents Chemother (2006) 1.14
IFN-gamma and IL-10 mediate parasite-specific immune responses of cord blood cells induced by pregnancy-associated Plasmodium falciparum malaria. J Immunol (2005) 1.14
Bone mineral density in children and adolescents with perinatal HIV infection. AIDS (2013) 1.13
Six genes are preferentially transcribed by the circulating and sequestered forms of Plasmodium falciparum parasites that infect pregnant women. Infect Immun (2007) 1.13
Mycobacterium tuberculosis-induced CXCR4 and chemokine expression leads to preferential X4 HIV-1 replication in human macrophages. J Immunol (2004) 1.11
The Plasmodium circumsporozoite protein is involved in mosquito salivary gland invasion by sporozoites. Mol Biochem Parasitol (2004) 1.10
Plasmodium sporozoite-host interactions from the dermis to the hepatocyte. Curr Opin Microbiol (2009) 1.10
Evidence that mutant PfCRT facilitates the transmission to mosquitoes of chloroquine-treated Plasmodium gametocytes. J Infect Dis (2011) 1.10
Natural selection of FLT1 alleles and their association with malaria resistance in utero. Proc Natl Acad Sci U S A (2008) 1.09
Body fat distribution in perinatally HIV-infected and HIV-exposed but uninfected children in the era of highly active antiretroviral therapy: outcomes from the Pediatric HIV/AIDS Cohort Study. Am J Clin Nutr (2011) 1.08
Chondroitin sulfate A-adhering Plasmodium falciparum-infected erythrocytes express functionally important antibody epitopes shared by multiple variants. J Immunol (2010) 1.08
Implications of malaria on iron deficiency control strategies. Adv Nutr (2012) 1.07
Adverse interactions between antifungal azoles and vincristine: review and analysis of cases. Mycoses (2011) 1.06
Role of molecular mimicry of hepatitis C virus protein with platelet GPIIIa in hepatitis C-related immunologic thrombocytopenia. Blood (2008) 1.06
NSR-seq transcriptional profiling enables identification of a gene signature of Plasmodium falciparum parasites infecting children. J Clin Invest (2011) 1.04
Immunization with radiation-attenuated Plasmodium berghei sporozoites induces liver cCD8alpha+DC that activate CD8+T cells against liver-stage malaria. PLoS One (2009) 1.04
Severe varicella caused by varicella-vaccine strain in a child with significant T-cell dysfunction. Pediatrics (2007) 1.02
Induction of T helper type 1 and 2 responses to 19-kilodalton merozoite surface protein 1 in vaccinated healthy volunteers and adults naturally exposed to malaria. Infect Immun (2002) 1.02
Effect of Ginkgo biloba extract on lopinavir, midazolam and fexofenadine pharmacokinetics in healthy subjects. Curr Med Res Opin (2008) 1.02
Diagnosing malaria in pregnancy: an update. Expert Rev Anti Infect Ther (2012) 1.01
Intermittent preventive treatment in pregnant women is associated with increased risk of severe malaria in their offspring. PLoS One (2013) 1.01
A plasma survey using 38 PfEMP1 domains reveals frequent recognition of the Plasmodium falciparum antigen VAR2CSA among young Tanzanian children. PLoS One (2012) 1.01
Pertussis booster vaccination in HIV-infected children receiving highly active antiretroviral therapy. Pediatrics (2007) 1.00
Pharmacokinetics and tolerability of oseltamivir combined with probenecid. Antimicrob Agents Chemother (2008) 1.00
Fetal responses during placental malaria modify the risk of low birth weight. Infect Immun (2008) 1.00
Efavirenz induces CYP2B6-mediated hydroxylation of bupropion in healthy subjects. J Acquir Immune Defic Syndr (2008) 1.00
HIV treatments have malaria gametocyte killing and transmission blocking activity. J Infect Dis (2013) 0.99