Published in J Clin Endocrinol Metab on March 01, 2005
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet (2007) 12.62
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A genome-wide association study identifies two new risk loci for Graves' disease. Nat Genet (2011) 1.92
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Genetic profiling in Graves' disease: further evidence for lack of a distinct genetic contribution to Graves' ophthalmopathy. Thyroid (2012) 0.89
A refined study of FCRL genes from a genome-wide association study for Graves' disease. PLoS One (2013) 0.89
Association between polymorphisms in the TSHR gene and Graves' orbitopathy. PLoS One (2014) 0.87
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Exon 33 T/T genotype of the thyroglobulin gene is a susceptibility gene for Graves' disease in Taiwanese and exon 12 C/C genotype protects against it. Clin Exp Med (2008) 0.79
Replication of association of nine susceptibility loci with Graves' disease in the Chinese Han population. Int J Clin Exp Med (2014) 0.78
Multiple SNPs in intron 41 of thyroglobulin gene are associated with autoimmune thyroid disease in the Japanese population. PLoS One (2012) 0.77
Epitope recognition in HLA-DR3 transgenic mice immunized to TSH-R protein or peptides. Endocrinology (2013) 0.77
An epistatic interaction between the PAX8 and STK17B genes in papillary thyroid cancer susceptibility. PLoS One (2013) 0.77
Association between TSHR gene polymorphism and the risk of Graves' disease: a meta-analysis. J Biomed Res (2015) 0.76
Genetic heterogeneity of susceptibility gene in different ethnic populations: refining association study of PTPN22 for Graves' disease in a Chinese Han population. PLoS One (2013) 0.76
The new perspectives on genetic studies of type 2 diabetes and thyroid diseases. Curr Genomics (2013) 0.75
Genetics of Thyroid-Stimulating Hormone Receptor-Relevance for Autoimmune Thyroid Disease. Front Endocrinol (Lausanne) (2017) 0.75
Thyrotropin Receptor Epitope and Human Leukocyte Antigen in Graves' Disease. Front Endocrinol (Lausanne) (2016) 0.75
Inherited polymorphisms in hyaluronan synthase 1 predict risk of systemic B-cell malignancies but not of breast cancer. PLoS One (2014) 0.75
Association of trypanolytic ApoL1 variants with kidney disease in African Americans. Science (2010) 16.00
MYH9 is a major-effect risk gene for focal segmental glomerulosclerosis. Nat Genet (2008) 9.00
4E-BP1 is a key effector of the oncogenic activation of the AKT and ERK signaling pathways that integrates their function in tumors. Cancer Cell (2010) 4.48
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13
Polymorphisms in the non-muscle myosin heavy chain 9 gene (MYH9) are strongly associated with end-stage renal disease historically attributed to hypertension in African Americans. Kidney Int (2009) 3.58
Heart transplantation in baboons using alpha1,3-galactosyltransferase gene-knockout pigs as donors: initial experience. Nat Med (2004) 3.58
Apolipoprotein L1 gene variants associate with hypertension-attributed nephropathy and the rate of kidney function decline in African Americans. Kidney Int (2012) 3.46
Tlx3 and Tlx1 are post-mitotic selector genes determining glutamatergic over GABAergic cell fates. Nat Neurosci (2004) 3.26
Hepatic steatosis and subclinical cardiovascular disease in a cohort enriched for type 2 diabetes: the Diabetes Heart Study. Am J Gastroenterol (2008) 3.16
A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities. Nat Genet (2005) 3.15
The apolipoprotein L1 (APOL1) gene and nondiabetic nephropathy in African Americans. J Am Soc Nephrol (2010) 3.15
Deregulation of the PI3K and KRAS signaling pathways in human cancer cells determines their response to everolimus. J Clin Invest (2010) 3.11
JC polyoma virus interacts with APOL1 in African Americans with nondiabetic nephropathy. Kidney Int (2013) 3.09
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. PLoS Genet (2011) 3.07
Reconstitution of a functional human immune system in immunodeficient mice through combined human fetal thymus/liver and CD34+ cell transplantation. Blood (2006) 2.94
Lymph node fibroblastic reticular cells construct the stromal reticulum via contact with lymphocytes. J Exp Med (2004) 2.91
Non-muscle myosin heavy chain 9 gene MYH9 associations in African Americans with clinically diagnosed type 2 diabetes mellitus-associated ESRD. Nephrol Dial Transplant (2009) 2.88
Genetic and environmental determinants of 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D levels in Hispanic and African Americans. J Clin Endocrinol Metab (2008) 2.87
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. Am J Hum Genet (2012) 2.53
Genetic epidemiology of insulin resistance and visceral adiposity. The IRAS Family Study design and methods. Ann Epidemiol (2003) 2.51
Dense mapping of MYH9 localizes the strongest kidney disease associations to the region of introns 13 to 15. Hum Mol Genet (2010) 2.51
Transcription-coupled events associating with immunoglobulin switch region chromatin. Science (2003) 2.50
Thyroid hormone action is disrupted by bisphenol A as an antagonist. J Clin Endocrinol Metab (2002) 2.49
Association analysis in african americans of European-derived type 2 diabetes single nucleotide polymorphisms from whole-genome association studies. Diabetes (2008) 2.41
Oncogenic events regulate tissue factor expression in colorectal cancer cells: implications for tumor progression and angiogenesis. Blood (2004) 2.41
Polymorphisms in MYH9 are associated with diabetic nephropathy in European Americans. Nephrol Dial Transplant (2011) 2.26
A link between FTO, ghrelin, and impaired brain food-cue responsivity. J Clin Invest (2013) 2.23
Proliferative glomerulonephritis with monoclonal immunoglobulin G3κ deposits in association with parvovirus B19 infection. Hum Pathol (2012) 2.16
Genetic factors in diabetic nephropathy. Clin J Am Soc Nephrol (2007) 2.03
A novel reticular stromal structure in lymph node cortex: an immuno-platform for interactions among dendritic cells, T cells and B cells. Int Immunol (2004) 2.02
A genome-wide association study for diabetic nephropathy genes in African Americans. Kidney Int (2010) 1.98
Pericardial and visceral adipose tissues measured volumetrically with computed tomography are highly associated in type 2 diabetic families. Invest Radiol (2005) 1.98
The balance between Pax5 and Id2 activities is the key to AID gene expression. J Exp Med (2003) 1.96
Renal disease in the elderly and the very elderly Japanese: analysis of the Japan Renal Biopsy Registry (J-RBR). Clin Exp Nephrol (2012) 1.95
Heritability of body composition measured by DXA in the diabetes heart study. Obes Res (2005) 1.94
Organizer-like reticular stromal cell layer common to adult secondary lymphoid organs. J Immunol (2008) 1.92
Variants of the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in an African-American population enriched for nephropathy. Diabetes (2007) 1.86
Roles of p-ERM and Rho-ROCK signaling in lymphocyte polarity and uropod formation. J Cell Biol (2004) 1.85
Relationship between albuminuria and cardiovascular disease in Type 2 diabetes. J Am Soc Nephrol (2005) 1.82
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nat Genet (2013) 1.82
UGT1A1*6 polymorphism is most predictive of severe neutropenia induced by irinotecan in Japanese cancer patients. Int J Clin Oncol (2009) 1.82
Genome-wide scans for diabetic nephropathy and albuminuria in multiethnic populations: the family investigation of nephropathy and diabetes (FIND). Diabetes (2007) 1.79
Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study. Diabetes (2008) 1.78
Heritability of carotid artery intima-medial thickness in type 2 diabetes. Stroke (2002) 1.78
Lbx1 and Tlx3 are opposing switches in determining GABAergic versus glutamatergic transmitter phenotypes. Nat Neurosci (2005) 1.73
A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One (2012) 1.72
Essential role of Id2 in negative regulation of IgE class switching. Nat Immunol (2002) 1.71
ANG II receptor blockade enhances anti-inflammatory macrophages in anti-glomerular basement membrane glomerulonephritis. Am J Physiol Renal Physiol (2010) 1.69
Chromogranin A polymorphisms are associated with hypertensive renal disease. J Am Soc Nephrol (2008) 1.68
APOL1 Genotype and Kidney Transplantation Outcomes From Deceased African American Donors. Transplantation (2016) 1.68
Vitamin d, adiposity, and calcified atherosclerotic plaque in african-americans. J Clin Endocrinol Metab (2010) 1.64
Genome-wide scan for estimated glomerular filtration rate in multi-ethnic diabetic populations: the Family Investigation of Nephropathy and Diabetes (FIND). Diabetes (2007) 1.61
Association of 25-hydroxyvitamin D with blood pressure in predominantly 25-hydroxyvitamin D deficient Hispanic and African Americans. Am J Hypertens (2009) 1.60
Antigen-specific human T-cell responses and T cell-dependent production of human antibodies in a humanized mouse model. Blood (2008) 1.60
Association of APOL1 variants with mild kidney disease in the first-degree relatives of African American patients with non-diabetic end-stage renal disease. Kidney Int (2012) 1.59
Informed conditioning on clinical covariates increases power in case-control association studies. PLoS Genet (2012) 1.57
Cytotoxic T-lymphocyte associated antigen 4 gene polymorphisms and autoimmune thyroid disease: a meta-analysis. J Clin Endocrinol Metab (2007) 1.57
Differential effects of MYH9 and APOL1 risk variants on FRMD3 Association with Diabetic ESRD in African Americans. PLoS Genet (2011) 1.57
alpha1,3-Galactosyltransferase gene-knockout pig heart transplantation in baboons with survival approaching 6 months. Transplantation (2005) 1.56
Association of NOS1AP genetic variants with QT interval duration in families from the Diabetes Heart Study. Diabetes (2008) 1.53
Race-specific relationships between coronary and carotid artery calcification and carotid intimal medial thickness. Stroke (2004) 1.53
Isolation and species distribution of staphylococci from animal and human skin. J Vet Med Sci (2002) 1.52
Plasma Dickkopf1 (DKK1) concentrations negatively associate with atherosclerotic calcified plaque in African-Americans with type 2 diabetes. J Clin Endocrinol Metab (2012) 1.52
Genome-wide association scan for survival on dialysis in African-Americans with type 2 diabetes. Am J Nephrol (2011) 1.52
Renoprotective effect of erythropoietin against ischaemia-reperfusion injury in a non-human primate model. Nephrol Dial Transplant (2010) 1.52
Sensitization to the lysosomal cell death pathway by oncogene-induced down-regulation of lysosome-associated membrane proteins 1 and 2. Cancer Res (2008) 1.50
TGF-beta receptor inactivation and mutant Kras induce intestinal neoplasms in mice via a beta-catenin-independent pathway. Gastroenterology (2009) 1.50
Quantitation of hepatitis B surface antigen by an automated chemiluminescent microparticle immunoassay. J Virol Methods (2004) 1.49
Heritability of GFR and albuminuria in Caucasians with type 2 diabetes mellitus. Am J Kidney Dis (2004) 1.47
BRAF and RAS oncogenes regulate Rho GTPase pathways to mediate migration and invasion properties in human colon cancer cells: a comparative study. Mol Cancer (2011) 1.47
Xenogeneic thymus transplantation in a pig-to-baboon model. Transplantation (2003) 1.47
Polycomb group suppressor of zeste 12 links heterochromatin protein 1alpha and enhancer of zeste 2. J Biol Chem (2003) 1.45
Chronic and recurrent otitis media: a genome scan for susceptibility loci. Am J Hum Genet (2004) 1.44
Plasma FGF23 and Calcified Atherosclerotic Plaque in African Americans with Type 2 Diabetes Mellitus. Am J Nephrol (2015) 1.42
Oncogenic K-RAS is required to maintain changes in cytoskeletal organization, adhesion, and motility in colon cancer cells. Cancer Res (2005) 1.41
Coronary calcium score and prediction of all-cause mortality in diabetes: the diabetes heart study. Diabetes Care (2011) 1.41
Acquired activated protein C resistance is associated with the co-existence of anti-prothrombin antibodies and lupus anticoagulant activity in patients with systemic lupus erythematosus. Br J Haematol (2002) 1.40
Increases of the Th1/Th2 cell ratio in severe Hashimoto's disease and in the proportion of Th17 cells in intractable Graves' disease. Thyroid (2009) 1.39
A single nucleotide polymorphism within the acetyl-coenzyme A carboxylase beta gene is associated with proteinuria in patients with type 2 diabetes. PLoS Genet (2010) 1.38
Activated forms of H-RAS and K-RAS differentially regulate membrane association of PI3K, PDK-1, and AKT and the effect of therapeutic kinase inhibitors on cell survival. Mol Cancer Ther (2005) 1.37
Analysis of FTO gene variants with measures of obesity and glucose homeostasis in the IRAS Family Study. Hum Genet (2009) 1.36
Exploration of the utility of ancestry informative markers for genetic association studies of African Americans with type 2 diabetes and end stage renal disease. Hum Genet (2008) 1.36
Peritubular capillary regression during the progression of experimental obstructive nephropathy. J Am Soc Nephrol (2002) 1.35
The impact of FADS genetic variants on ω6 polyunsaturated fatty acid metabolism in African Americans. BMC Genet (2011) 1.35
Inhibition of CCR2 ameliorates insulin resistance and hepatic steatosis in db/db mice. Arterioscler Thromb Vasc Biol (2008) 1.34
Variability of serum soluble intercellular adhesion molecule-1 measurements attributable to a common polymorphism. Clin Chem (2004) 1.33
A leucine repeat in the carnosinase gene CNDP1 is associated with diabetic end-stage renal disease in European Americans. Nephrol Dial Transplant (2007) 1.33
SNPs in the promoter of a B cell-specific antisense transcript, SAS-ZFAT, determine susceptibility to autoimmune thyroid disease. Hum Mol Genet (2004) 1.32
Proper development of relay somatic sensory neurons and D2/D4 interneurons requires homeobox genes Rnx/Tlx-3 and Tlx-1. Genes Dev (2002) 1.32
Survivin depletion preferentially reduces the survival of activated K-Ras-transformed cells. Mol Cancer Ther (2007) 1.31
A genome scan for ESRD in black families enriched for nondiabetic nephropathy. J Am Soc Nephrol (2004) 1.30
Resequencing and analysis of variation in the TCF7L2 gene in African Americans suggests that SNP rs7903146 is the causal diabetes susceptibility variant. Diabetes (2010) 1.30
Genomic structure and characterization of the 5'-flanking region of the human ghrelin gene. Endocrinology (2004) 1.30
Sleep duration and five-year abdominal fat accumulation in a minority cohort: the IRAS family study. Sleep (2010) 1.29
Heritability of the severity of diabetic retinopathy: the FIND-Eye study. Invest Ophthalmol Vis Sci (2008) 1.29
Pharmacokinetics, safety, and endocrine and appetite effects of ghrelin administration in young healthy subjects. Eur J Endocrinol (2004) 1.29
Association of PNPLA3 with non-alcoholic fatty liver disease in a minority cohort: the Insulin Resistance Atherosclerosis Family Study. Liver Int (2011) 1.27
A genome-wide scan for type 2 diabetes in African-American families reveals evidence for a locus on chromosome 6q. Diabetes (2004) 1.26
Knock-down of 25 kDa subunit of cleavage factor Im in Hela cells alters alternative polyadenylation within 3'-UTRs. Nucleic Acids Res (2006) 1.26