Published in N Engl J Med on August 21, 1975
Effect of cimetidine on 24-hour intragastric acidity in normal subjects. Gut (1976) 3.75
Inhibition of food-stimulated gastric acid secretion by cimetidine. Gut (1976) 1.82
The absorption of cimetidine before and during maintenance treatment with cimetidine and the influence of a meal on the absorption of cimetidine--studies in patients with peptic ulcer disease. Br J Clin Pharmacol (1979) 1.59
Relationship between asthma and gastro-oesophageal reflux. Thorax (1981) 1.45
Nocturnal metiamide treatment in the management of healed duodenal ulceration. Gut (1977) 1.24
Inhibition of gastric acid secretion in the dog by the H2-receptor antagonists, ranitidine, cimetidine, and metiamide. Gut (1980) 1.23
Randomized prospective evaluation of cimetidine and antacid control of gastric pH in the critically ill. Ann Surg (1980) 0.99
Inhibition of food stimulated acid secretion by fenoctimine, a new anti-secretory agent. Br J Clin Pharmacol (1983) 0.92
Effect of prolonged cimetidine therapy on gastric acid secretion in man. Gut (1978) 0.91
Cimetidine absorption in humans during sucralfate coadministration. Br J Clin Pharmacol (1986) 0.87
Is the measurement of blood cimetidine levels useful? Br J Clin Pharmacol (1981) 0.86
Pharmacokinetics of mifentidine after single and multiple oral administration to healthy volunteers. Br J Clin Pharmacol (1988) 0.80
Effect of metiamide on basal and stimulated serum cholecystokinin levels in duodenal ulcer patients. Gut (1976) 0.80
Cimetidine enhancement of cyclophosphamide antitumour activity. Br J Cancer (1982) 0.80
Inhibitory effect of cimetidine on gastric acid secretion vagally activated by physiological means in duodenal ulcer patients. Gut (1978) 0.77
Editorial: Histamine antagonists and peptic ulcer. Br Med J (1976) 0.75
Acid suppression therapy and allergic reactions. Allergo J Int (2015) 0.75
Population pharmacokinetic analysis of rebamipide in healthy Korean subjects with the characterization of atypical complex absorption kinetics. J Pharmacokinet Pharmacodyn (2017) 0.75
Healing of duodenal ulcer with an antacid regimen. N Engl J Med (1977) 3.32
Metiamide, an H2-receptor blocker, as inhibitor of basal and meal-stimulated gastric acid secretion in patients with duodenal ulcer. N Engl J Med (1974) 2.22
Increased sensitivity to stimulation of acid secretion by pentagastrin in duodenal ulcer. J Clin Invest (1975) 2.08
Increased prevalence of cholelithiasis in men ingesting a serum-cholesterol-lowering diet. N Engl J Med (1973) 2.05
Gastric acid secretion is abnormally sensitive to endogenous gastrin released after peptone test meals in duodenal ulcer patients. J Clin Invest (1980) 2.03
National Cooperative Crohn's Disease Study: adverse reactions to study drugs. Gastroenterology (1979) 1.94
Zollinger-Ellison syndrome. Gastroenterology (1973) 1.79
Azathioprine-related pancreatitis in patients with Crohn's disease. Gastroenterology (1979) 1.68
Intravenous infusion of amino acids stimulates gastric acid secretion in man. N Engl J Med (1978) 1.63
Clearance and acid-stimulating action of human big and little gastrins in duodenal ulcer subjects. J Clin Invest (1976) 1.57
Unusual effect of secretin on serum gastrin, serum calcium, and gastric acid secretion in a patient with suspected Zollinger-Ellison syndrome. Gastroenterology (1972) 1.50
Cimetidine versus intensive antacid therapy for duodenal ulcer: a multicenter trial. Gastroenterology (1978) 1.47
Bicarbonate transport by rabbit duodenum in vitro: effect of vasoactive intestinal polypeptide, prostaglandin E2, and cyclic adenosine monophosphate. Gastroenterology (1993) 1.45
Pulmonary vasculitis--an uncommon complication of ulcerative colitis. Report of a case. N Engl J Med (1968) 1.44
Identification of transport abnormalities in duodenal mucosa and duodenal enterocytes from patients with cystic fibrosis. Gastroenterology (2000) 1.43
Impaired proximal duodenal mucosal bicarbonate secretion in patients with duodenal ulcer. N Engl J Med (1987) 1.43
Stimulation of gastric secretion and gastrin release by single oral doses of calcium carbonate in man. N Engl J Med (1973) 1.40
Cholecystokinin receptor antagonist MK-329 blocks intestinal fat-induced inhibition of meal-stimulated gastric acid secretion. Gastroenterology (1992) 1.40
The effect of 16,16-dimethyl prostaglandin E2 on meal-stimulated gastric acid secretion and serum gastrin in duodenal ulcer patients. Gastroenterology (1976) 1.37
Human duodenal mucosal bicarbonate secretion. Evidence for basal secretion and stimulation by hydrochloric acid and a synthetic prostaglandin E1 analogue. Gastroenterology (1986) 1.31
Gastroduodenal mucosal alkaline secretion and mucosal protection. News Physiol Sci (2001) 1.30
Antacid and placebo produced similar pain relief in duodenal ulcer patients. Gastroenterology (1977) 1.27
The training and role of the physician assistant in oncologic practice. PA J (1976) 1.25
Duodenal bicarbonate secretion: eradication of Helicobacter pylori and duodenal structure and function in humans. Gastroenterology (1996) 1.22
Similar acid stimulatory potencies of synthetic human big and little gastrins in man. J Clin Invest (1984) 1.18
Metoclopramide stimulates prolactin secretion in man. J Clin Endocrinol Metab (1976) 1.18
CFTR mediates cAMP- and Ca2+-activated duodenal epithelial HCO3- secretion. Am J Physiol (1997) 1.17
Rapid gastric emptying in duodenal ulcer patients. Dig Dis Sci (1982) 1.17
Effect of octapeptide of cholecystokinin on canine pyloric pressure. Am J Physiol (1972) 1.11
Healing of benign gastric ulcer with low-dose antacid or cimetidine. A double-blind, randomized, placebo-controlled trial. N Engl J Med (1983) 1.10
Acid-stimulated duodenal bicarbonate secretion involves a CFTR-mediated transport pathway in mice. Gastroenterology (1997) 1.10
Effect of fat on meal-stimulated duodenal acid load, duodenal pepsin load, and serum gastrin in duodenal ulcer and normal subjects. Gastroenterology (1978) 1.07
Use of C-terminal octapeptide of cholecystokinin in cholecystography. Am J Roentgenol Radium Ther Nucl Med (1974) 1.06
The effect of various forms of milk on gastric-acid secretion. Studies in patients with duodenal ulcer and normal subjects. Ann Intern Med (1976) 1.06
Esophageal disease in patients with angina-like chest pain. Am J Gastroenterol (1981) 1.04
Effect of gastrin and SC 15396 on gastric motility in dogs. Gastroenterology (1969) 1.03
Comparison of synthetic and natural porcine secretins on human pancreatic secretion. Gastroenterology (1974) 1.02
Midazolam, a new more potent benzodiazepine, compared with diazepam: a randomized, double-blind study of preendoscopic sedatives. Gastrointest Endosc (1983) 1.02
HLA-B5 associated with duodenal ulcer. Gastroenterology (1977) 1.01
Gastrin is a major mediator of the gastric phase of acid secretion in dogs: proof by monoclonal antibody neutralization. Gastroenterology (1989) 1.01
Intravenous infusion of L-isomers of phenylalanine and tryptophan stimulate gastric acid secretion at physiologic plasma concentrations in normal subjects and after parietal cell vagotomy. J Clin Invest (1983) 1.01
Relative stimulatory effects of commonly ingested beverages on gastric acid secretion in humans. Gastroenterology (1982) 0.99
A new method for quantitation of ion fluxes across in vivo human gastric mucosa: effect of aspirin, acetaminophen, ethanol, and hyperosmolar solutions. Gastroenterology (1984) 0.98
Peptic ulcer: epidemiology, nutritional aspects, drugs, smoking, alcohol, and diet. Curr Concepts Nutr (1980) 0.98
Nasogastric suction in the treatment of alcoholic pancreatitis. A controlled study. JAMA (1974) 0.98
Relation of gastric secretory response in man to dose of insulin. Gastroenterology (1969) 0.98
Epidemiology of peptic ulcer: report of a conference. Am J Epidemiol (1976) 0.98
Effect of graded doses of intraluminal H+, prostaglandin E2, and inhibition of endogenous prostaglandin synthesis on proximal duodenal bicarbonate secretion in unanesthetized rat. Gastroenterology (1985) 0.98
Review article: gastroduodenal bicarbonate secretion. Aliment Pharmacol Ther (1994) 0.98
Effect of graded amounts of acid instilled into the duodenum on pancreatic bicarbonate secretion and plasma secretin in duodenal ulcer patients and normal subjects. Gastroenterology (1977) 0.97
Effect of oral and intravenous 16,16-dimethyl prostaglandin E2 in duodenal ulcer and Zollinger-Ellison syndrome patients. Gastroenterology (1981) 0.97
Cholecystokinin both stimulates and inhibits human food intake. Nature (1976) 0.96
An apparent exception to Schwarz's dictum, "no acid--no ulcer". N Engl J Med (1971) 0.96
Insulin-induced acid secretion after partial vagotomy in dogs and cats. Am J Physiol (1969) 0.96
Patient acceptance and effectiveness of a balanced lavage solution (Golytely) versus the standard preparation for colonoscopy. Gastroenterology (1982) 0.95
Effect of the C-terminal octapeptide of cholecystokinin on lower esophageal sphincter pressure in man. Gastroenterology (1973) 0.95
Prevention by glucagon of experimental stress induced hemorrhagic gastritis. Gastroenterology (1975) 0.95
Effect of cholestyramine on the symptoms of reflux gastritis. A randomized, double blind, crossover study. Gastroenterology (1977) 0.95
Effect of gastric inhibitory polypeptide on pentagastrin-stimulated acid secretion in man. Dig Dis Sci (1980) 0.93
Effect of metoclopramide in chronic gastric retention after gastric surgery. Gastroenterology (1976) 0.93
Comparative effects of metoclopramide and bethanechol on lower esophageal sphincter pressure in reflux patients. Gastroenterology (1975) 0.92
Protective effect of acetaminophen against aspirin- and ethanol-induced damage to the human gastric mucosa. Gastroenterology (1984) 0.92
Treatment of hemorrhagic gastritis with 15(R)-15 methyl prostaglandin E2: report of a case. Gastroenterology (1982) 0.91
Wine and five percent ethanol are potent stimulants of gastric acid secretion in humans. Gastroenterology (1983) 0.91
Metabolic profiles of montelukast sodium (Singulair), a potent cysteinyl leukotriene1 receptor antagonist, in human plasma and bile. Drug Metab Dispos (1997) 0.90
The natural antibody response to E. coli includes antibodies of the IgD class. Clin Exp Immunol (1978) 0.89
Most patients with active symptomatic duodenal ulcers fail to develop ulcer-type pain in response to gastroduodenal acidification. J Clin Gastroenterol (1982) 0.89
Glucose perfusion intragastric titration. Dig Dis Sci (1984) 0.88
Bombesin stimulates human gastric function by gastrin-dependent and independent mechanisms. Peptides (1981) 0.87
Effects of the octapeptide of cholecystokinin on insulin and glucagon secretion in the dog. Endocrinology (1975) 0.87
Human duodenal mucosal brush border Na(+)/H(+) exchangers NHE2 and NHE3 alter net bicarbonate movement. Am J Physiol Gastrointest Liver Physiol (2001) 0.87
Bolus or intravenous infusion of ranitidine: effects on gastric pH and acid secretion. A comparison of relative efficacy and cost. Ann Intern Med (1990) 0.86
Cigarette smoking inhibits acid-stimulated duodenal mucosal bicarbonate secretion. Ann Intern Med (1993) 0.86
Indomethacin inhibits duodenal mucosal bicarbonate secretion and endogenous prostaglandin E2 output in human subjects. Ann Intern Med (1987) 0.86
Measurement of gastric bicarbonate secretion in the human stomach: different methods produce discordant results. Scand J Gastroenterol (1992) 0.86
Duodenal bicarbonate secretion in humans. Role of prostaglandins. Dig Dis Sci (1986) 0.85
Comparison of metoclopramide with other dynamic tests of prolactin secretion. J Clin Endocrinol Metab (1976) 0.85
H2-receptor antagonists in the treatment of peptic ulcer. Ann Intern Med (1976) 0.85
The effects of graded doses of C-terminal octapeptide of cholecystokinin on small intestinal transit time in man. Am J Dig Dis (1974) 0.85
Effect of intravenous lipid on gastric acid secretion stimulated by intravenous amino acids. Gastroenterology (1980) 0.84
Cimetidine decreases aspirin-induced gastric mucosal damage in humans. Aliment Pharmacol Ther (1987) 0.84
Proximal duodenal prostaglandin E2 release and mucosal bicarbonate secretion are altered in patients with duodenal ulcer. Gastroenterology (1990) 0.84
Diuretic action of secretin in dog. Proc Soc Exp Biol Med (1972) 0.84
Ascites with peritoneal involvement in Whipple's disease. Report of a case. Gastroenterology (1971) 0.84
Editorial: Is gastrin the major regulator of lower esophageal sphincter pressure? Gastroenterology (1974) 0.84
A controlled trial of metoclopramide in symptomatic gastroesophageal reflux. N Engl J Med (1977) 0.83