Published in Mol Immunol on July 01, 1990
The MACPF/CDC family of pore-forming toxins. Cell Microbiol (2008) 2.15
Essential role of membrane-attack protein in malarial transmission to mosquito host. Proc Natl Acad Sci U S A (2004) 1.65
A null mutation in the perforin gene impairs cytolytic T lymphocyte- and natural killer cell-mediated cytotoxicity. Proc Natl Acad Sci U S A (1994) 1.30
Cytolytic and antibacterial activity of synthetic peptides derived from amoebapore, the pore-forming peptide of Entamoeba histolytica. Proc Natl Acad Sci U S A (1994) 1.12
Presence of plasma complement regulatory proteins clusterin (Apo J) and vitronectin (S40) on circulating immune complexes (CIC). Clin Exp Immunol (2006) 1.06
Primary and secondary structure of the pore-forming peptide of pathogenic Entamoeba histolytica. EMBO J (1992) 1.04
Primary structure of an apical protein from Xenopus laevis that participates in amiloride-sensitive sodium channel activity. J Cell Biol (1992) 0.99
Mutation of recombinant complement component C9 reveals the significance of the N-terminal region for polymerization. Immunology (1997) 0.92
Biological characterization of Chlamydia trachomatis plasticity zone MACPF domain family protein CT153. Infect Immun (2010) 0.87
Solution structure of factor I-like modules from complement C7 reveals a pair of follistatin domains in compact pseudosymmetric arrangement. J Biol Chem (2009) 0.81
Topology of the membrane-bound form of complement protein C9 probed by glycosylation mapping, anti-peptide antibody binding, and disulfide modification. Mol Immunol (2010) 0.81
The mystery behind membrane insertion: a review of the complement membrane attack complex. Philos Trans R Soc Lond B Biol Sci (2017) 0.78
Molecular characterization of the alpha subunit of complement component C8 (GcC8alpha) in the nurse shark (Ginglymostoma cirratum). Fish Shellfish Immunol (2009) 0.77
Membrane pore formation by human complement: functional importance of the transmembrane β-hairpin (TMH) segments of C8α and C9. Mol Immunol (2013) 0.75
A novel pathogenic variant in PRF1 associated with hemophagocytic lymphohistiocytosis. J Clin Immunol (2015) 0.75
Enhanced graphic matrix analysis of nucleic acid and protein sequences. Proc Natl Acad Sci U S A (1981) 46.11
Molecular weight estimation of polypeptide chains by electrophoresis in SDS-polyacrylamide gels. Biochem Biophys Res Commun (1967) 32.60
The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA. Nature (1989) 13.92
Evidence for virus-specific noncapsid proteins in poliovirus-infected HeLa cells. Proc Natl Acad Sci U S A (1965) 11.84
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009. Cell Death Differ (2008) 10.45
Acrylamide-gel electrophorograms by mechanical fractionation: radioactive adenovirus proteins. Science (1966) 9.59
Inhibition of death receptor signals by cellular FLIP. Nature (1997) 9.58
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death Differ (2007) 8.85
Cloned human and mouse kappa immunoglobulin constant and J region genes conserve homology in functional segments. Cell (1980) 8.77
Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule. Nat Immunol (2000) 8.49
Evidence for large precursor proteins in poliovirus synthesis. Proc Natl Acad Sci U S A (1968) 8.24
The evolution and sequence comparison of two recently diverged mouse chromosomal beta--globin genes. Cell (1979) 8.11
The polypeptides of adenovirus. I. Evidence for multiple protein components in the virion and a comparison of types 2, 7A, and 12. Virology (1968) 7.42
Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations. J Exp Med (1999) 7.41
The nucleotide sequence of a 5.5-kilobase DNA segment containing the mouse kappa immunoglobulin J and C region genes. J Biol Chem (1981) 7.26
BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth. J Exp Med (1999) 6.27
Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors. Nature (1997) 6.23
Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape. Science (1996) 6.02
Increased neurovirulence associated with a single nucleotide change in a noncoding region of the Sabin type 3 poliovaccine genome. Nature (1985) 6.01
Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways. Nature (1994) 5.58
Properties of a normal mouse cell DNA sequence (sarc) homologous to the src sequence of Moloney sarcoma virus. Science (1980) 5.30
BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF. Science (2001) 4.79
NF-kappaB signals induce the expression of c-FLIP. Mol Cell Biol (2001) 4.55
The polypeptides of adenovirus. II. Soluble proteins, cores, top components and the structure of the virion. Virology (1968) 4.19
Inflammatory caspases and inflammasomes: master switches of inflammation. Cell Death Differ (2006) 4.16
Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes. J Exp Med (1991) 4.15
Intervening sequence of DNA identified in the structural portion of a mouse beta-globin gene. Proc Natl Acad Sci U S A (1978) 4.02
Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity. J Exp Med (1998) 3.72
Polyribosomal synthesis and assembly of the H and L chains of gamma globulin. Proc Natl Acad Sci U S A (1966) 3.53
Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death Differ (2009) 3.44
BAFF mediates survival of peripheral immature B lymphocytes. J Exp Med (2000) 3.43
Evolution of human immunoglobulin kappa J region genes. J Biol Chem (1982) 3.41
The decrease in size and synthetic activity of poliovirus polysomes late in the infectious cycle. Virology (1967) 3.41
T7-directed protein synthesis. Virology (1969) 3.32
Comparative sequence analysis of the 5' noncoding region of the enteroviruses and rhinoviruses. Virology (1988) 3.30
Synthesis and structure of Caulobacter crescentus flagella. J Bacteriol (1973) 3.28
APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth. J Exp Med (1998) 3.17
The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways. Curr Biol (2000) 3.12
MyD88, an adapter protein involved in interleukin-1 signaling. J Biol Chem (1998) 3.09
Comparative analysis of the HTLV-I Rex and HIV-1 Rev trans-regulatory proteins and their RNA response elements. Genes Dev (1989) 3.09
Structural proteins of adenovirus-associated viruses. J Virol (1971) 3.03
Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis. Immunity (1998) 3.03
Hidden from view: violent deaths among pregnant women in the District of Columbia, 1988-1996. J Midwifery Womens Health (2001) 2.95
Bcl-2 decreases the free Ca2+ concentration within the endoplasmic reticulum. Proc Natl Acad Sci U S A (2000) 2.87
Inhibition of toxic epidermal necrolysis by blockade of CD95 with human intravenous immunoglobulin. Science (1998) 2.84
Determination of the gene sequence of poliovirus with pactamycin. Proc Natl Acad Sci U S A (1971) 2.80
TRAIL receptor-2 signals apoptosis through FADD and caspase-8. Nat Cell Biol (2000) 2.80
Isolation of a viral polypeptide associated with poliovirus RNA polymerase. Proc Natl Acad Sci U S A (1974) 2.79
Caspase activation is required for T cell proliferation. J Exp Med (1999) 2.74
YidC, the Escherichia coli homologue of mitochondrial Oxa1p, is a component of the Sec translocase. EMBO J (2000) 2.70
BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population. J Exp Med (2000) 2.69
Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor. Nat Cell Biol (2000) 2.66
Isolation of a lytic, pore-forming protein (perforin) from cytolytic T-lymphocytes. J Biol Chem (1985) 2.62
TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB. Immunity (1997) 2.60
Molecular substructure of a viral receptor-recognition protein. The gp17 tail-fiber of bacteriophage T7. J Mol Biol (1988) 2.59
A family of serine esterases in lytic granules of cytolytic T lymphocytes. Cell (1987) 2.58
Evidence for high-energy extraterrestrial neutrinos at the IceCube detector. Science (2013) 2.56
Studies of the mechanism of enhancement of human adenovirus infection in monkey cells by simian virus 40. J Virol (1972) 2.55
In vitro assembly of poliovirus-related particles. Virology (1968) 2.55
Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death). EMBO J (1993) 2.50
The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing. Cell Death Differ (2007) 2.49
The Sec61p complex mediates the integration of a membrane protein by allowing lipid partitioning of the transmembrane domain. Cell (2000) 2.46
The pyrin domain: a possible member of the death domain-fold family implicated in apoptosis and inflammation. Curr Biol (2001) 2.43
Clusterin: the intriguing guises of a widely expressed glycoprotein. Trends Biochem Sci (1992) 2.40
Formation of transmembrane tubules by spontaneous polymerization of the hydrophilic complement protein C9. Nature (1982) 2.35
Single bilayer vesicles prepared without sonication. Physico-chemical properties. Biochim Biophys Acta (1976) 2.32
The protein-conducting channel in the membrane of the endoplasmic reticulum is open laterally toward the lipid bilayer. Cell (1995) 2.27
Synthesis and assembly of adenovirus 2. I. Polypeptide synthesis, assembly of capsomeres, and morphogenesis of the virion. Virology (1969) 2.27
Soluble RNA polymerase complex from poliovirus-infected HeLa cells. Virology (1970) 2.26
Evidence for differences in size and composition of the poliovirus-specific polypeptides in infected HeLa cells. Virology (1968) 2.23
The protein bcl-2 alpha does not require membrane attachment, but two conserved domains to suppress apoptosis. J Cell Biol (1994) 2.20
A 42K outer-membrane protein is a component of the yeast mitochondrial protein import site. Nature (1989) 2.18
The sequence and topology of human complement component C9. EMBO J (1985) 2.18
Signals from within: the DNA-damage-induced NF-kappaB response. Cell Death Differ (2006) 2.16
The polypeptides of adenovirus. V. Young virions, structural intermediate between top components and aged virions. Virology (1974) 2.15
Fas and Fas ligand in embryos and adult mice: ligand expression in several immune-privileged tissues and coexpression in adult tissues characterized by apoptotic cell turnover. J Cell Biol (1996) 2.14
Inhibition of cleavage of large poliovirus-specific precursor proteins in infected HeLa cells by inhibitors of proteolytic enzymes. J Virol (1972) 2.06
A common RNA structural motif involved in the internal initiation of translation of cellular mRNAs. Nucleic Acids Res (1997) 2.05
Regulation of lymphocyte proliferation and death by FLIP. Nat Rev Immunol (2001) 2.04
The CARD domain: a new apoptotic signalling motif. Trends Biochem Sci (1997) 2.02
Correlation between splicing sites within an intron and their sequence complementarity with U1 RNA. Cell (1980) 2.02
First observation of PeV-energy neutrinos with IceCube. Phys Rev Lett (2013) 2.00
Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x(L). Proc Natl Acad Sci U S A (1999) 1.99
The polypeptides of adenovirus. VI. Early and late glycopolypeptides. Virology (1974) 1.98
Identification of CARDIAK, a RIP-like kinase that associates with caspase-1. Curr Biol (1998) 1.97
Identification of a putative membrane receptor for the bioactive phospholipid, lysophosphatidic acid. EMBO J (1992) 1.97
Polymerization of the ninth component of complement (C9): formation of poly(C9) with a tubular ultrastructure resembling the membrane attack complex of complement. Proc Natl Acad Sci U S A (1982) 1.96
Hydrophobic binding of the ectodomain of influenza hemagglutinin to membranes occurs through the "fusion peptide". J Biol Chem (1989) 1.96
Sequence of reovirus haemagglutinin predicts a coiled-coil structure. Nature (1985) 1.95
Evidence for ambiguity in the posttranslational cleavage of poliovirus proteins. Virology (1970) 1.93
Molecular weight estimation of polypeptides by SDS-polyacrylamide gel electrophoresis: further data concerning resolving power and general considerations. Anal Biochem (1969) 1.92
A highly conserved RNA folding region coincident with the Rev response element of primate immunodeficiency viruses. Nucleic Acids Res (1990) 1.90
Ceramide enables fas to cap and kill. J Biol Chem (2001) 1.88
Functional comparison of the Rev trans-activators encoded by different primate immunodeficiency virus species. Proc Natl Acad Sci U S A (1989) 1.87
A program for predicting significant RNA secondary structures. Comput Appl Biosci (1988) 1.87
Molecular structure and functional characterization of a human complement cytolysis inhibitor found in blood and seminal plasma: identity to sulfated glycoprotein 2, a constituent of rat testis fluid. Proc Natl Acad Sci U S A (1989) 1.85
In vitro protein synthetic activity of membrane-bound poliovirus polyribosomes. Virology (1971) 1.84
A soluble form of B cell maturation antigen, a receptor for the tumor necrosis factor family member APRIL, inhibits tumor cell growth. J Exp Med (2000) 1.83
Characterization of two receptors for TRAIL. FEBS Lett (1997) 1.82