Published in Appl Environ Microbiol on August 16, 2013
Improved catalytic efficiency, thermophilicity, anti-salt and detergent tolerance of keratinase KerSMD by partially truncation of PPC domain. Sci Rep (2016) 0.75
Significantly enhancing recombinant alkaline amylase production in Bacillus subtilis by integration of a novel mutagenesis-screening strategy with systems-level fermentation optimization. J Biol Eng (2016) 0.75
SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling. Electrophoresis (1997) 57.27
Toward the estimation of the absolute quality of individual protein structure models. Bioinformatics (2010) 5.08
X-ray structures along the reaction pathway of cyclodextrin glycosyltransferase elucidate catalysis in the alpha-amylase family. Nat Struct Biol (1999) 2.58
Directed evolution of biocatalysts. Curr Opin Chem Biol (1999) 2.12
The effect of high-frequency random mutagenesis on in vitro protein evolution: a study on TEM-1 beta-lactamase. J Mol Biol (1999) 2.00
Misuse of graphical analysis in nonlinear sugar transport kinetics by Eadie-Hofstee plots. Biochim Biophys Acta (1993) 1.21
New type of starch-binding domain: the direct repeat motif in the C-terminal region of Bacillus sp. no. 195 alpha-amylase contributes to starch binding and raw starch degrading. Biochem J (2000) 1.05
From protein engineering to immobilization: promising strategies for the upgrade of industrial enzymes. Int J Mol Sci (2013) 1.00
Engineering by homologous recombination: exploring sequence and function within a conserved fold. Curr Opin Struct Biol (2007) 1.00
Protein engineering of microbial enzymes. Curr Opin Microbiol (2010) 0.98
A truncated Fibrobacter succinogenes 1,3-1,4-beta-d-glucanase with improved enzymatic activity and thermotolerance. Biochemistry (2005) 0.96
High-level expression of a truncated 1,3-1,4-beta-D-glucanase from Fibrobacter succinogenes in Pichia pastoris by optimization of codons and fermentation. Appl Microbiol Biotechnol (2007) 0.96
Truncation of N- and C-terminal regions of Streptococcus mutans dextranase enhances catalytic activity. Appl Microbiol Biotechnol (2011) 0.95
Enhanced catalytic efficiency of aminoglycoside phosphotransferase (3')-IIa achieved through protein fragmentation and reassembly. J Mol Biol (2005) 0.95
Engineering of the alpha-amylase from Geobacillus stearothermophilus US100 for detergent incorporation. Biotechnol Bioeng (2009) 0.94
Gene cloning and characterization of a novel alpha-amylase from alkaliphilic Alkalimonas amylolytica. Biotechnol J (2006) 0.90
Deduced amino-acid sequence of a calcium-free alpha-amylase from a strain of Bacillus: implications from molecular modeling of high oxidation stability and chelator resistance of the enzyme. Eur J Biochem (2001) 0.89
A bioconjugate of Pseudomonas cepacia lipase with alginate with enhanced catalytic efficiency. Biochim Biophys Acta (2006) 0.89
A novel approach for enhancing the catalytic efficiency of a protease at low temperature: reduction in substrate inhibition by chemical modification. Biotechnol Bioeng (2009) 0.87
Fusion of an oligopeptide to the N terminus of an alkaline α-amylase from Alkalimonas amylolytica simultaneously improves the enzyme's catalytic efficiency, thermal stability, and resistance to oxidation. Appl Environ Microbiol (2013) 0.86
Construction of a fully active truncated alternansucrase partially deleted of its carboxy-terminal domain. FEBS Lett (2006) 0.86
Site-specific saturation mutagenesis on residues 132 and 450 of Candida rugosa LIP2 enhances catalytic efficiency and alters substrate specificity in various chain lengths of triglycerides and esters. J Agric Food Chem (2010) 0.83
Ca2+-surfactant interactions affect enzyme stability in detergent solutions. Biotechnol Prog (2005) 0.81
Structure-based redesign of GST A2-2 for enhanced catalytic efficiency with azathioprine. Chem Biol (2012) 0.78
Engineering Klebsiella sp. 601 multicopper oxidase enhances the catalytic efficiency towards phenolic substrates. BMC Biochem (2011) 0.77
Human infection with a novel avian-origin influenza A (H7N9) virus. N Engl J Med (2013) 24.88
Approaches to catheter ablation for persistent atrial fibrillation. N Engl J Med (2015) 6.68
Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice. Nat Immunol (2007) 6.67
Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model. Cancer Cell (2009) 4.82
TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment. Neuron (2008) 4.00
Pten haploinsufficiency accelerates formation of high-grade astrocytomas. Cancer Res (2008) 3.99
The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor. Cell (2003) 3.36
High-performance thin-film transistors using semiconductor nanowires and nanoribbons. Nature (2003) 3.01
Amplicon melting analysis with labeled primers: a closed-tube method for differentiating homozygotes and heterozygotes. Clin Chem (2003) 2.91
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. Genome Res (2003) 2.91
Essential and overlapping functions for mammalian Argonautes in microRNA silencing. Genes Dev (2009) 2.73
Why mothers stop breastfeeding: mothers' self-reported reasons for stopping during the first year. Pediatrics (2008) 2.68
Novel reassortant highly pathogenic H5N2 avian influenza viruses in poultry in China. PLoS One (2012) 2.43
Cerebral white matter lesions, gait, and the risk of incident falls: a prospective population-based study. Stroke (2008) 2.32
High operative risk of cool-tip radiofrequency ablation for unresectable pancreatic head cancer. J Surg Oncol (2006) 2.19
The insulin-regulated CREB coactivator TORC promotes stress resistance in Drosophila. Cell Metab (2008) 2.09
Upregulation of a T-type Ca2+ channel causes a long-lasting modification of neuronal firing mode after status epilepticus. J Neurosci (2002) 2.09
Infant Feeding Practices Study II: study methods. Pediatrics (2008) 2.05
A genome-wide association study in Han Chinese identifies multiple susceptibility loci for IgA nephropathy. Nat Genet (2011) 1.77
A novel software platform for medical image processing and analyzing. IEEE Trans Inf Technol Biomed (2008) 1.72
Brain atrophy in type 2 diabetes: regional distribution and influence on cognition. Diabetes Care (2013) 1.71
EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer. BMC Cancer (2012) 1.70
Aurora B kinase phosphorylates and instigates degradation of p53. Proc Natl Acad Sci U S A (2012) 1.66
PTEN regulates collagen-induced platelet activation. Blood (2010) 1.60
Enhancing collaborative filtering by user interest expansion via personalized ranking. IEEE Trans Syst Man Cybern B Cybern (2011) 1.58
Identification of acyl coenzyme A:monoacylglycerol acyltransferase 3, an intestinal specific enzyme implicated in dietary fat absorption. J Biol Chem (2003) 1.57
MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity. Brain Res (2010) 1.56
Subunit 6 of the COP9 signalosome promotes tumorigenesis in mice through stabilization of MDM2 and is upregulated in human cancers. J Clin Invest (2011) 1.54
CXCR4/CXCL12 mediate autocrine cell- cycle progression in NF1-associated malignant peripheral nerve sheath tumors. Cell (2013) 1.53
Hypoxia induces adhesion molecules on cancer cells: A missing link between Warburg effect and induction of selectin-ligand carbohydrates. Proc Natl Acad Sci U S A (2004) 1.50
The Th17/Treg functional imbalance during atherogenesis in ApoE(-/-) mice. Cytokine (2009) 1.48
Left-behind children in rural China experience higher levels of anxiety and poorer living conditions. Acta Paediatr (2014) 1.47
Changes of soil organic carbon in an intensively cultivated agricultural region: a denitrification-decomposition (DNDC) modelling approach. Sci Total Environ (2006) 1.45
Expression cloning of functional receptor used by SARS coronavirus. Biochem Biophys Res Commun (2004) 1.44
Incidence and significance of early recurrences associated with different ablation strategies for AF: a STAR-AF substudy. J Cardiovasc Electrophysiol (2012) 1.44
Controlled assembly of carbon nanotubes by designed amphiphilic Peptide helices. J Am Chem Soc (2003) 1.40
gamma-Cyclodextrin: a review on enzymatic production and applications. Appl Microbiol Biotechnol (2007) 1.39
Flexible solid-state supercapacitors based on carbon nanoparticles/MnO2 nanorods hybrid structure. ACS Nano (2011) 1.39
Therapeutic potential of mesenchymal stem cells producing interferon-alpha in a mouse melanoma lung metastasis model. Stem Cells (2008) 1.38
Inositol hexakisphosphate mobilizes an endomembrane store of calcium in guard cells. Proc Natl Acad Sci U S A (2003) 1.37
Expression and characterization of human transient receptor potential melastatin 3 (hTRPM3). J Biol Chem (2003) 1.37
Application of minimally invasive treatment for early gastric cancer. J Surg Oncol (2004) 1.37
Immune-deficient Drosophila melanogaster: a model for the innate immune response to human fungal pathogens. J Immunol (2004) 1.33
New advances in plant growth-promoting rhizobacteria for bioremediation. Environ Int (2007) 1.31
Overexpression of activation-induced cytidine deaminase in B cells is associated with production of highly pathogenic autoantibodies. J Immunol (2007) 1.30
Expression of an Arabidopsis vacuolar H+-pyrophosphatase gene (AVP1) in cotton improves drought- and salt tolerance and increases fibre yield in the field conditions. Plant Biotechnol J (2011) 1.30
Survival benefit of metastasectomy for Krukenberg tumors from gastric cancer. Gynecol Oncol (2004) 1.29
Temporally specified genetic ablation of neurogenesis impairs cognitive recovery after traumatic brain injury. J Neurosci (2011) 1.29
Analysis of 3 algorithms for syphilis serodiagnosis and implications for clinical management. Clin Infect Dis (2014) 1.29
Isthmus characteristics of reentrant ventricular tachycardia after myocardial infarction. Circulation (2002) 1.27
Exploring off-targets and off-systems for adverse drug reactions via chemical-protein interactome--clozapine-induced agranulocytosis as a case study. PLoS Comput Biol (2011) 1.26
Substrate and Trigger Ablation for Reduction of Atrial Fibrillation (STAR AF): a randomized, multicentre, international trial. Eur Heart J (2010) 1.25
High performance, waveguide integrated Ge photodetectors. Opt Express (2007) 1.25
Quantifying the complexity of bat wing kinematics. J Theor Biol (2008) 1.24
DRAR-CPI: a server for identifying drug repositioning potential and adverse drug reactions via the chemical-protein interactome. Nucleic Acids Res (2011) 1.23
Glutathione: a review on biotechnological production. Appl Microbiol Biotechnol (2004) 1.22
An ultra-high density bin-map for rapid QTL mapping for tassel and ear architecture in a large F₂ maize population. BMC Genomics (2014) 1.22
Highly infectious SARS-CoV pseudotyped virus reveals the cell tropism and its correlation with receptor expression. Biochem Biophys Res Commun (2004) 1.20
Qiliqiangxin regulates the balance between tumor necrosis factor-alpha and interleukin-10 and improves cardiac function in rats with myocardial infarction. Cell Immunol (2009) 1.19
CSF-1 receptor structure/function in MacCsf1r-/- macrophages: regulation of proliferation, differentiation, and morphology. J Leukoc Biol (2008) 1.19
Extensive, clustered parental imprinting of protein-coding and noncoding RNAs in developing maize endosperm. Proc Natl Acad Sci U S A (2011) 1.19
Menetrier's disease in korea: report of two cases and review of cases in a gastric cancer prevalent region. Yonsei Med J (2004) 1.18
High DcR3 expression predicts stage pN2 in gastric cancer. Hepatogastroenterology (2008) 1.18
Harvesting candidate genes responsible for serious adverse drug reactions from a chemical-protein interactome. PLoS Comput Biol (2009) 1.18
Manganese exposure among smelting workers: relationship between blood manganese-iron ratio and early onset neurobehavioral alterations. Neurotoxicology (2009) 1.17
Differential expression of Rab27A/B correlates with clinical outcome in hepatocellular carcinoma. World J Gastroenterol (2012) 1.16
Targeting TGF-β signaling in cancer. Expert Opin Ther Targets (2013) 1.16
In vivo measurement of brain GABA concentrations by magnetic resonance spectroscopy in smelters occupationally exposed to manganese. Environ Health Perspect (2010) 1.16
Continuous flow microfluidic device for cell separation, cell lysis and DNA purification. Anal Chim Acta (2006) 1.16
Antineoplastic effects of an Aurora B kinase inhibitor in breast cancer. Mol Cancer (2010) 1.15
Hydrodynamic tweezers: 1. Noncontact trapping of single cells using steady streaming microeddies. Anal Chem (2006) 1.15
A monoclonal antibody to visualize PtdIns(3,4,5)P(3) in cells. J Histochem Cytochem (2002) 1.14
Identification and characteristics of microRNAs from Bombyx mori. BMC Genomics (2008) 1.14
Identification and characterization of bacterial cutinase. J Biol Chem (2008) 1.13
Meta-analysis of factors which influence delirium following cardiac surgery. J Card Surg (2012) 1.13
The impact of type 2 diabetes and antidiabetic drugs on cancer cell growth. J Cell Mol Med (2011) 1.12
Genome sequence of a natural reassortant H5N2 avian influenza virus from domestic mallard ducks in eastern China. J Virol (2012) 1.12
Production of a novel polygalacturonic acid bioflocculant REA-11 by Corynebacterium glutamicum. Bioresour Technol (2004) 1.12
Effects of extraction solvent mixtures on antioxidant activity evaluation and their extraction capacity and selectivity for free phenolic compounds in barley (Hordeum vulgare L.). J Agric Food Chem (2006) 1.11
Glial scar expression of CHL1, the close homolog of the adhesion molecule L1, limits recovery after spinal cord injury. J Neurosci (2007) 1.11
Biotransformation and volatilization of arsenic by three photosynthetic cyanobacteria. Plant Physiol (2011) 1.11
Manganese exposure among smelting workers: blood manganese-iron ratio as a novel tool for manganese exposure assessment. Biomarkers (2009) 1.11
HER2-Akt signaling in regulating COP9 signalsome subunit 6 and p53. Cell Cycle (2012) 1.11
Grafts of Schwann cells engineered to express PSA-NCAM promote functional recovery after spinal cord injury. Brain (2007) 1.11
14-3-3sigma exerts tumor-suppressor activity mediated by regulation of COP1 stability. Cancer Res (2010) 1.11
Development of a new tool to correlate stroke outcome with infarct topography: a proof-of-concept study. Neuroimage (2009) 1.10
Roles for CSN5 in control of p53/MDM2 activities. J Cell Biochem (2008) 1.10
WO3–x@Au@MnO2 core–shell nanowires on carbon fabric for high-performance flexible supercapacitors. Adv Mater (2012) 1.10
SePreSA: a server for the prediction of populations susceptible to serious adverse drug reactions implementing the methodology of a chemical-protein interactome. Nucleic Acids Res (2009) 1.10
Does night work increase the risk of breast cancer? A systematic review and meta-analysis of epidemiological studies. Cancer Epidemiol (2013) 1.10
Human alphaA- and alphaB-crystallins prevent UVA-induced apoptosis through regulation of PKCalpha, RAF/MEK/ERK and AKT signaling pathways. Exp Eye Res (2004) 1.10
Mitochondrial genome analysis of Ochotona curzoniae and implication of cytochrome c oxidase in hypoxic adaptation. Mitochondrion (2008) 1.09
Microbial production of hyaluronic acid: current state, challenges, and perspectives. Microb Cell Fact (2011) 1.09
Adrenomedullin antagonist suppresses in vivo growth of human pancreatic cancer cells in SCID mice by suppressing angiogenesis. Oncogene (2003) 1.08
Correlated stage- and subfield-associated hippocampal gene expression patterns in experimental and human temporal lobe epilepsy. Eur J Neurosci (2003) 1.08
Cutinase-like proteins of Mycobacterium tuberculosis: characterization of their variable enzymatic functions and active site identification. FASEB J (2009) 1.07