Published in Curr Genomics on March 01, 2013
Synthetic biology for pharmaceutical drug discovery. Drug Des Devel Ther (2015) 0.75
In vivo evolution of metabolic pathways: Assembling old parts to build novel and functional structures. Bioengineered (2014) 0.75
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci U S A (1992) 35.45
Characterization of the reconstructed 1918 Spanish influenza pandemic virus. Science (2005) 17.19
Land clearing and the biofuel carbon debt. Science (2008) 15.51
Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets. Nature (2012) 14.17
Production of the antimalarial drug precursor artemisinic acid in engineered yeast. Nature (2006) 13.86
Use of U.S. croplands for biofuels increases greenhouse gases through emissions from land-use change. Science (2008) 13.74
Airborne transmission of influenza A/H5N1 virus between ferrets. Science (2012) 13.48
Creation of a bacterial cell controlled by a chemically synthesized genome. Science (2010) 13.45
Biodiesel from microalgae. Biotechnol Adv (2007) 9.61
Grand challenges in chronic non-communicable diseases. Nature (2007) 7.86
Synthetic biology: applications come of age. Nat Rev Genet (2010) 6.96
Carbon-negative biofuels from low-input high-diversity grassland biomass. Science (2006) 6.86
Engineering a mevalonate pathway in Escherichia coli for production of terpenoids. Nat Biotechnol (2003) 6.74
Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels. Nature (2008) 6.68
Microbial production of fatty-acid-derived fuels and chemicals from plant biomass. Nature (2010) 5.84
Computational design of receptor and sensor proteins with novel functions. Nature (2003) 5.48
Isoprenoid pathway optimization for Taxol precursor overproduction in Escherichia coli. Science (2010) 4.96
Reprogramming cellular behavior with RNA controllers responsive to endogenous proteins. Science (2010) 4.78
Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans. Nature (2011) 4.61
Environmentally controlled invasion of cancer cells by engineered bacteria. J Mol Biol (2005) 4.25
An outlook on microalgal biofuels. Science (2010) 4.20
Feedstocks for lignocellulosic biofuels. Science (2010) 3.81
Multi-input RNAi-based logic circuit for identification of specific cancer cells. Science (2011) 3.76
Direct photosynthetic recycling of carbon dioxide to isobutyraldehyde. Nat Biotechnol (2009) 3.63
Synthetic genetic polymers capable of heredity and evolution. Science (2012) 3.59
Metabolic engineering of Escherichia coli for direct production of 1,4-butanediol. Nat Chem Biol (2011) 3.55
Synthetic genomics | options for governance. Biosecur Bioterror (2007) 3.26
Field performance of engineered male mosquitoes. Nat Biotechnol (2011) 3.25
Targeted and armed oncolytic poxviruses: a novel multi-mechanistic therapeutic class for cancer. Nat Rev Cancer (2009) 3.06
Potent and nontoxic antisense oligonucleotides containing locked nucleic acids. Proc Natl Acad Sci U S A (2000) 3.04
Reprogrammed viruses as cancer therapeutics: targeted, armed and shielded. Nat Rev Microbiol (2008) 3.01
Female-specific flightless phenotype for mosquito control. Proc Natl Acad Sci U S A (2010) 2.92
Metabolic engineering of microorganisms for biofuels production: from bugs to synthetic biology to fuels. Curr Opin Biotechnol (2008) 2.80
Sustainability metrics: life cycle assessment and green design in polymers. Environ Sci Technol (2010) 2.77
A synthetic optogenetic transcription device enhances blood-glucose homeostasis in mice. Science (2011) 2.77
Fatty acid production in genetically modified cyanobacteria. Proc Natl Acad Sci U S A (2011) 2.77
Indirect emissions from biofuels: how important? Science (2009) 2.71
Engineering the perfect (bacterial) cancer therapy. Nat Rev Cancer (2010) 2.70
Assemblage of ortho cleavage route for simultaneous degradation of chloro- and methylaromatics. Science (1987) 2.62
Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids. Nat Biotechnol (2012) 2.55
Production of cyclic peptides and proteins in vivo. Proc Natl Acad Sci U S A (1999) 2.42
Retracted Reprogramming bacteria to seek and destroy an herbicide. Nat Chem Biol (2010) 2.39
Indirect land-use changes can overcome carbon savings from biofuels in Brazil. Proc Natl Acad Sci U S A (2010) 2.32
A synthetic homing endonuclease-based gene drive system in the human malaria mosquito. Nature (2011) 2.20
Driving forces enable high-titer anaerobic 1-butanol synthesis in Escherichia coli. Appl Environ Microbiol (2011) 2.19
A sensing array of radically coupled genetic 'biopixels'. Nature (2011) 2.18
Genetic elimination of dengue vector mosquitoes. Proc Natl Acad Sci U S A (2011) 2.08
Green fluorescent protein as a vital marker and reporter of gene expression in Drosophila. Proc Natl Acad Sci U S A (1995) 2.04
Live attenuated influenza virus vaccines by computer-aided rational design. Nat Biotechnol (2010) 1.98
Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice. Proc Natl Acad Sci U S A (2008) 1.97
Engineering a mouse metallothionein on the cell surface of Ralstonia eutropha CH34 for immobilization of heavy metals in soil. Nat Biotechnol (2000) 1.82
Enzyme mechanism as a kinetic control element for designing synthetic biofuel pathways. Nat Chem Biol (2011) 1.81
Synthesis of three advanced biofuels from ionic liquid-pretreated switchgrass using engineered Escherichia coli. Proc Natl Acad Sci U S A (2011) 1.75
Synthetic biology: Four steps to avoid a synthetic-biology disaster. Nature (2012) 1.74
A synthetic mammalian gene circuit reveals antituberculosis compounds. Proc Natl Acad Sci U S A (2008) 1.68
Where microbiology meets microengineering: design and applications of reporter bacteria. Nat Rev Microbiol (2010) 1.66
Self-sufficient control of urate homeostasis in mice by a synthetic circuit. Nat Biotechnol (2010) 1.64
Metabolic engineering of cyanobacteria for 1-butanol production from carbon dioxide. Metab Eng (2011) 1.62
Newtons of the leaves of grass. Nat Biotechnol (2008) 1.61
Short hairpin RNA-expressing bacteria elicit RNA interference in mammals. Nat Biotechnol (2006) 1.61
Retracted Selective cell death mediated by small conditional RNAs. Proc Natl Acad Sci U S A (2010) 1.51
Synthetic viruses: a new opportunity to understand and prevent viral disease. Nat Biotechnol (2009) 1.47
An economic and technical evaluation of microalgal biofuels. Nat Biotechnol (2010) 1.44
Integrated electromicrobial conversion of CO2 to higher alcohols. Science (2012) 1.42
Novel antisense and peptide nucleic acid strategies for controlling gene expression. Biochemistry (2002) 1.40
Synthetic biology: discovering new worlds and new words. EMBO Rep (2008) 1.35
Benefits and risks of influenza research: lessons learned. Science (2012) 1.33
Transgenic mosquitoes and the fight against malaria: managing technology push in a turbulent GMO world. Am J Trop Med Hyg (2007) 1.32
Bioremediation approaches for organic pollutants: a critical perspective. Environ Int (2011) 1.31
Renewable fuels from algae: an answer to debatable land based fuels. Bioresour Technol (2010) 1.30
Rapid, simple, quantitative, and highly sensitive antibody detection for lyme disease. Clin Vaccine Immunol (2010) 1.25
Drug delivery trends in clinical trials and translational medicine: challenges and opportunities in the delivery of nucleic acid-based therapeutics. J Pharm Sci (2011) 1.24
Improvement of light to biomass conversion by de-regulation of light-harvesting protein translation in Chlamydomonas reinhardtii. J Biotechnol (2009) 1.24
Scientific standards and the regulation of genetically modified insects. PLoS Negl Trop Dis (2012) 1.23
Inhibition of HIV budding by a genetically selected cyclic peptide targeting the Gag-TSG101 interaction. ACS Chem Biol (2008) 1.23
Metabolic engineering of Clostridium cellulolyticum for production of isobutanol from cellulose. Appl Environ Microbiol (2011) 1.22
Genetically engineered bacteria: an emerging tool for environmental remediation and future research perspectives. Gene (2011) 1.19
Engineering photosynthetic light capture: impacts on improved solar energy to biomass conversion. Plant Biotechnol J (2007) 1.19
Selectively replicating adenoviruses targeting deregulated E2F activity are potent, systemic antitumor agents. Cancer Cell (2002) 1.18
Tracing explosives in soil with transcriptional regulators of Pseudomonas putida evolved for responding to nitrotoluenes. Microb Biotechnol (2008) 1.17
Locked nucleic acids: promising nucleic acid analogs for therapeutic applications. Chem Biodivers (2010) 1.12
Synthetic constructs in/for the environment: managing the interplay between natural and engineered Biology. FEBS Lett (2012) 1.09
Production of polyhydroxybutyrate in switchgrass, a value-added co-product in an important lignocellulosic biomass crop. Plant Biotechnol J (2008) 1.07
Rewiring hydrogenase-dependent redox circuits in cyanobacteria. Proc Natl Acad Sci U S A (2011) 1.06
Synergies between synthetic biology and metabolic engineering. Nat Biotechnol (2011) 1.06
Microalgal hydrogen production. Curr Opin Biotechnol (2010) 1.04
Metabolic and practical considerations on microbial electrosynthesis. Curr Opin Biotechnol (2011) 1.03
Synthetic biology and patents. A European perspective. EMBO Rep (2009) 1.02
Engineering. Cellulosic biofuels--got gasoline? Science (2009) 1.01
Xenobiology: a new form of life as the ultimate biosafety tool. Bioessays (2010) 1.00
Bacterial bioassay for rapid and accurate analysis of arsenic in highly variable groundwater samples. Environ Sci Technol (2005) 1.00
Demand for malaria drug soars. Nature (2010) 0.98
Metabolic engineering of bacteria for environmental applications: construction of Pseudomonas strains for biodegradation of 2-chlorotoluene. J Biotechnol (2001) 0.97
Synthetic biology confronts publics and policy makers: challenges for communication, regulation and commercialization. Trends Biotechnol (2011) 0.97
Analysis of novel soluble chromate and uranyl reductases and generation of an improved enzyme by directed evolution. Appl Environ Microbiol (2006) 0.97
Dual-use research and technological diffusion: reconsidering the bioterrorism threat spectrum. PLoS Pathog (2011) 0.96
Fermentation of 10% (w/v) sugar to D: (-)-lactate by engineered Escherichia coli B. Biotechnol Lett (2005) 0.96
The farther, the safer: a manifesto for securely navigating synthetic species away from the old living world. Syst Synth Biol (2009) 0.94
Ethics. Ethical framework for biofuels. Science (2011) 0.91
Use of genetically engineered microorganisms (GEMs) for the bioremediation of contaminants. Crit Rev Biotechnol (2006) 0.91
Similarities and differences between selective and nonselective BAFF blockade in murine SLE. J Clin Invest (2006) 2.05
Assessing the outcome of compulsory treatment orders on management of psychiatric patients at 2 McGill University-associated hospitals. Can J Psychiatry (2012) 0.97
Molecular cloning and DNA binding characterization of DAF-16 orthologs from Ancylostoma hookworms. Int J Parasitol (2008) 0.96
A phase II study of capecitabine and lapatinib in advanced refractory colorectal adenocarcinoma: A Wisconsin Oncology Network study. J Gastrointest Oncol (2012) 0.95
Structural and conformational properties and intramolecular hydrogen bonding of (methylenecyclopropyl)methanol, as studied by microwave spectroscopy and quantum chemical calculations. J Phys Chem A (2006) 0.88
The microvascular anatomy of the metatarsal bones: a plastination study. Surg Radiol Anat (2008) 0.87
Surgical treatment of AVN of the fibular (lateral) sesamoid. Foot Ankle Int (2008) 0.83
Arterial anatomy of the hallucal sesamoids. Clin Anat (2009) 0.82
Primary 1-arylcyclopropylamines from aryl cyanides with diethylzinc and titanium alkoxides. Org Lett (2003) 0.79
Treatment of isolated peroneus longus tears and a review of the literature. Foot Ankle Spec (2013) 0.76
Octacyclopropylcubane and some of its isomers. Angew Chem Int Ed Engl (2007) 0.75
Re: in debate: does psychoanalysis have a future? Can J Psychiatry (2006) 0.75
Domino 6pi-electrocyclization/Diels-Alder reactions on 1,6-disubstituted (E,Z,E)-1,3,5-hexatrienes: versatile access to highly substituted tri- and tetracyclic systems. Chemistry (2005) 0.75
[DKOU 2010]. Z Orthop Unfall (2010) 0.75
Syntheses and properties of enantiomerically pure higher (n > or = 7) [n-2]triangulanedimethanols and sigma-[n]helicenes. Chemistry (2006) 0.75
Stereoselective preparation of six diastereomeric quatercyclopropanes from bicyclopropylidene and some derivatives. Chemistry (2007) 0.75
Synthetic biology's self-fulfilling prophecy--dangers of confinement from within and outside. Biotechnol J (2014) 0.75
Radical cation of a trimethylenemethane with a nondegenerate ground state. J Am Chem Soc (2005) 0.75
[In Process Citation]. Chirurg (2007) 0.75
A convergent route to enantiomerically pure higher [n-2]triangulanedimethanol derivatives and [n]triangulanes (n>/=7). Angew Chem Int Ed Engl (2004) 0.75
Diels-Alder reactions of novel (1'-arylallylidene)cyclopropanes with heterodienophiles. Chem Asian J (2007) 0.75
[Cheilectomy and Kessel-Bonney procedure for treatment of initial hallux rigidus]. Oper Orthop Traumatol (2008) 0.75