Published in EMBO Rep on September 10, 2013
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Checkpoint kinases and the INO80 nucleosome remodeling complex enhance global chromatin mobility in response to DNA damage. Genes Dev (2013) 1.12
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Functional targeting of DNA damage to a nuclear pore-associated SUMO-dependent ubiquitin ligase. Science (2008) 3.09
The Smc5-Smc6 complex and SUMO modification of Rad52 regulates recombinational repair at the ribosomal gene locus. Nat Cell Biol (2007) 2.56
Double-strand breaks in heterochromatin move outside of a dynamic HP1a domain to complete recombinational repair. Cell (2011) 2.50
DNA damage and mutagenesis by radiomimetic DNA-cleaving agents: bleomycin, neocarzinostatin and other enediynes. Mutat Res (1996) 2.46
Identification of protein complexes required for efficient sister chromatid cohesion. Mol Biol Cell (2004) 2.34
Mechanisms of programmed DNA lesions and genomic instability in the immune system. Cell (2013) 2.32
DNA breaks promote genomic instability by impeding proper chromosome segregation. Curr Biol (2004) 2.14
Mechanisms that regulate localization of a DNA double-strand break to the nuclear periphery. Genes Dev (2009) 2.13
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The positioning and dynamics of origins of replication in the budding yeast nucleus. J Cell Biol (2001) 2.05
Increased chromosome mobility facilitates homology search during recombination. Nat Cell Biol (2012) 1.88
Increased mobility of double-strand breaks requires Mec1, Rad9 and the homologous recombination machinery. Nat Cell Biol (2012) 1.86
DNA double-strand breaks in heterochromatin elicit fast repair protein recruitment, histone H2AX phosphorylation and relocation to euchromatin. Nucleic Acids Res (2011) 1.72
Smc5-Smc6 mediate DNA double-strand-break repair by promoting sister-chromatid recombination. Nat Cell Biol (2006) 1.71
Chromatin movement in the maintenance of genome stability. Cell (2013) 1.59
Double-strand breaks arising by replication through a nick are repaired by cohesin-dependent sister-chromatid exchange. EMBO Rep (2006) 1.51
Effect of nuclear architecture on the efficiency of double-strand break repair. Nat Cell Biol (2013) 1.45
Targeted INO80 enhances subnuclear chromatin movement and ectopic homologous recombination. Genes Dev (2012) 1.36
Budding yeast Wapl controls sister chromatid cohesion maintenance and chromosome condensation. Curr Biol (2012) 1.24
The cis element and factors required for condensin recruitment to chromosomes. Mol Cell (2009) 1.22
Regulation of nuclear positioning and dynamics of the silent mating type loci by the yeast Ku70/Ku80 complex. Mol Cell Biol (2008) 1.19
Visualizing yeast chromosomes and nuclear architecture. Methods Enzymol (2010) 1.18
Eukaryotic DNA damage checkpoint activation in response to double-strand breaks. Cell Mol Life Sci (2011) 1.11
Cohesin association to replication sites depends on rad50 and promotes fork restart. Mol Cell (2012) 1.10
Suppression of the double-strand-break-repair defect of the Saccharomyces cerevisiae rad57 mutant. Genetics (2009) 1.01
Histone H3 lysine 56 acetylation and the response to DNA replication fork damage. Mol Cell Biol (2011) 0.97
Rad51 replication fork recruitment is required for DNA damage tolerance. EMBO J (2013) 0.91
A Flp-nick system to study repair of a single protein-bound nick in vivo. Nat Methods (2009) 0.89
Histone H3K56 acetylation, Rad52, and non-DNA repair factors control double-strand break repair choice with the sister chromatid. PLoS Genet (2013) 0.88
Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair. Cell (2004) 4.76
Crosstalk between histone modifications during the DNA damage response. Trends Cell Biol (2009) 4.31
The nuclear envelope and transcriptional control. Nat Rev Genet (2007) 3.81
Automatic tracking of individual fluorescence particles: application to the study of chromosome dynamics. IEEE Trans Image Process (2005) 3.64
Gene regulation through nuclear organization. Nat Struct Mol Biol (2007) 3.44
Nuclear pore association confers optimal expression levels for an inducible yeast gene. Nature (2006) 3.39
DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1. EMBO J (2003) 3.15
Functional targeting of DNA damage to a nuclear pore-associated SUMO-dependent ubiquitin ligase. Science (2008) 3.09
Long-range compaction and flexibility of interphase chromatin in budding yeast analyzed by high-resolution imaging techniques. Proc Natl Acad Sci U S A (2004) 2.99
The histone code at DNA breaks: a guide to repair? Nat Rev Mol Cell Biol (2005) 2.97
Live imaging of telomeres: yKu and Sir proteins define redundant telomere-anchoring pathways in yeast. Curr Biol (2002) 2.92
Step-wise methylation of histone H3K9 positions heterochromatin at the nuclear periphery. Cell (2012) 2.67
Separation of silencing from perinuclear anchoring functions in yeast Ku80, Sir4 and Esc1 proteins. EMBO J (2004) 2.47
ORC and the intra-S-phase checkpoint: a threshold regulates Rad53p activation in S phase. Genes Dev (2002) 2.40
Distinct roles for SWR1 and INO80 chromatin remodeling complexes at chromosomal double-strand breaks. EMBO J (2007) 2.23
Heterochromatin protein 1: don't judge the book by its cover! Curr Opin Genet Dev (2006) 2.20
Replisome instability, fork collapse, and gross chromosomal rearrangements arise synergistically from Mec1 kinase and RecQ helicase mutations. Genes Dev (2005) 2.17
Chromosome looping in yeast: telomere pairing and coordinated movement reflect anchoring efficiency and territorial organization. J Cell Biol (2005) 2.16
The function of nuclear architecture: a genetic approach. Annu Rev Genet (2004) 2.06
Sir-mediated repression can occur independently of chromosomal and subnuclear contexts. Cell (2004) 2.04
The spatial dynamics of tissue-specific promoters during C. elegans development. Genes Dev (2010) 2.00
Cdk2 suppresses cellular senescence induced by the c-myc oncogene. Nat Cell Biol (2009) 1.99
Mechanistically distinct roles for Sgs1p in checkpoint activation and replication fork maintenance. EMBO J (2004) 1.94
RecQ helicases: multiple roles in genome maintenance. Trends Cell Biol (2003) 1.91
Ino80 chromatin remodeling complex promotes recovery of stalled replication forks. Curr Biol (2008) 1.89
Increased mobility of double-strand breaks requires Mec1, Rad9 and the homologous recombination machinery. Nat Cell Biol (2012) 1.86
Pathogen-induced systemic plant signal triggers DNA rearrangements. Nature (2003) 1.77
The nuclear envelope--a scaffold for silencing? Curr Opin Genet Dev (2009) 1.65
ATR/Mec1: coordinating fork stability and repair. Curr Opin Cell Biol (2009) 1.64
Reconstitution of yeast silent chromatin: multiple contact sites and O-AADPR binding load SIR complexes onto nucleosomes in vitro. Mol Cell (2009) 1.61
Yeast telomerase and the SUN domain protein Mps3 anchor telomeres and repress subtelomeric recombination. Genes Dev (2009) 1.59
Chromatin movement in the maintenance of genome stability. Cell (2013) 1.59
The functional importance of telomere clustering: global changes in gene expression result from SIR factor dispersion. Genome Res (2009) 1.56
An N-terminal domain of Dbf4p mediates interaction with both origin recognition complex (ORC) and Rad53p and can deregulate late origin firing. Proc Natl Acad Sci U S A (2002) 1.55
Temporal separation of replication and recombination requires the intra-S checkpoint. J Cell Biol (2005) 1.54
Controlled exchange of chromosomal arms reveals principles driving telomere interactions in yeast. Genome Res (2007) 1.48
The origin recognition complex functions in sister-chromatid cohesion in Saccharomyces cerevisiae. Cell (2007) 1.47
An EDMD mutation in C. elegans lamin blocks muscle-specific gene relocation and compromises muscle integrity. Curr Biol (2011) 1.43
The budding yeast nucleus. Cold Spring Harb Perspect Biol (2010) 1.43
Structure and function in the budding yeast nucleus. Genetics (2012) 1.37
Silent chromatin at the middle and ends: lessons from yeasts. EMBO J (2009) 1.36
Targeted INO80 enhances subnuclear chromatin movement and ectopic homologous recombination. Genes Dev (2012) 1.36
Myosin-like proteins 1 and 2 are not required for silencing or telomere anchoring, but act in the Tel1 pathway of telomere length control. J Struct Biol (2002) 1.34
Intracellular trafficking of yeast telomerase components. EMBO Rep (2002) 1.34
Replication foci dynamics: replication patterns are modulated by S-phase checkpoint kinases in fission yeast. EMBO J (2007) 1.30
The processing of double-strand breaks and binding of single-strand-binding proteins RPA and Rad51 modulate the formation of ATR-kinase foci in yeast. J Cell Sci (2007) 1.28
ATP-dependent chromatin remodeling and DNA double-strand break repair. Cell Cycle (2005) 1.27
Locking the genome: nuclear organization and cell fate. Curr Opin Genet Dev (2011) 1.22
Methods for visualizing chromatin dynamics in living yeast. Methods Enzymol (2004) 1.20
Nucleosome remodelers in double-strand break repair. Curr Opin Genet Dev (2013) 1.20
Regulation of nuclear positioning and dynamics of the silent mating type loci by the yeast Ku70/Ku80 complex. Mol Cell Biol (2008) 1.19
Actin-related proteins in the nucleus: life beyond chromatin remodelers. Curr Opin Cell Biol (2010) 1.18
Visualizing yeast chromosomes and nuclear architecture. Methods Enzymol (2010) 1.18
RecQ helicases: at the heart of genetic stability. FEBS Lett (2002) 1.17
The PIAS homologue Siz2 regulates perinuclear telomere position and telomerase activity in budding yeast. Nat Cell Biol (2011) 1.17
Nuclear organization and silencing: putting things in their place. Nat Cell Biol (2002) 1.14
Nuclear geometry and rapid mitosis ensure asymmetric episome segregation in yeast. Curr Biol (2010) 1.13
Promoter- and RNA polymerase II-dependent hsp-16 gene association with nuclear pores in Caenorhabditis elegans. J Cell Biol (2013) 1.13
Nuclear organization in genome stability: SUMO connections. Cell Res (2011) 1.13
Mechanisms of heterochromatin subnuclear localization. Trends Biochem Sci (2013) 1.12
Checkpoint kinases and the INO80 nucleosome remodeling complex enhance global chromatin mobility in response to DNA damage. Genes Dev (2013) 1.12
Modules for cloning-free chromatin tagging in Saccharomyces cerevisae. Yeast (2008) 1.12
TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks. Mol Cell (2013) 1.07
Multiple pathways tether telomeres and silent chromatin at the nuclear periphery: functional implications for sir-mediated repression. Novartis Found Symp (2005) 1.06
Multiple pathways for telomere tethering: functional implications of subnuclear position for heterochromatin formation. Biochim Biophys Acta (2004) 1.05
In and out of the replication factory. Cell (2006) 1.03
A homotrimer-heterotrimer switch in Sir2 structure differentiates rDNA and telomeric silencing. Mol Cell (2006) 1.03
SIR proteins and the assembly of silent chromatin in budding yeast. Annu Rev Genet (2013) 1.00
A dual role of H4K16 acetylation in the establishment of yeast silent chromatin. EMBO J (2011) 1.00
Subtelomeric factors antagonize telomere anchoring and Tel1-independent telomere length regulation. EMBO J (2006) 1.00
Ribosome biogenesis factors bind a nuclear envelope SUN domain protein to cluster yeast telomeres. EMBO J (2011) 0.99
An N-terminal acidic region of Sgs1 interacts with Rpa70 and recruits Rad53 kinase to stalled forks. EMBO J (2012) 0.99
Structural basis for the role of the Sir3 AAA+ domain in silencing: interaction with Sir4 and unmethylated histone H3K79. Genes Dev (2011) 0.98
Redundancy, insult-specific sensors and thresholds: unlocking the S-phase checkpoint response. Curr Opin Genet Dev (2004) 0.96
Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry. ACS Chem Biol (2012) 0.95
CENTRIN2 interacts with the Arabidopsis homolog of the human XPC protein (AtRAD4) and contributes to efficient synthesis-dependent repair of bulky DNA lesions. Plant Mol Biol (2006) 0.94
Actin-related protein Arp6 influences H2A.Z-dependent and -independent gene expression and links ribosomal protein genes to nuclear pores. PLoS Genet (2010) 0.94
Dot1 binding induces chromatin rearrangements by histone methylation-dependent and -independent mechanisms. Epigenetics Chromatin (2011) 0.91
Cell cycle-dependent phosphorylation of Rad53 kinase by Cdc5 and Cdc28 modulates checkpoint adaptation. Cell Cycle (2010) 0.90
Epigenetics in Saccharomyces cerevisiae. Cold Spring Harb Perspect Biol (2013) 0.90
Early initiation of a replication origin tethered at the nuclear periphery. J Cell Sci (2010) 0.89
Agrobacterium proteins VirD2 and VirE2 mediate precise integration of synthetic T-DNA complexes in mammalian cells. EMBO Rep (2004) 0.87
RecQ helicases and genome stability: lessons from model organisms and human disease. Swiss Med Wkly (2002) 0.87
Posttranslational modifications of repair factors and histones in the cellular response to stalled replication forks. DNA Repair (Amst) (2009) 0.86
SIR-nucleosome interactions: structure-function relationships in yeast silent chromatin. Gene (2013) 0.85
Caenorhabditis elegans Heterochromatin protein 1 (HPL-2) links developmental plasticity, longevity and lipid metabolism. Genome Biol (2011) 0.85
γH2A is a component of yeast heterochromatin required for telomere elongation. Cell Cycle (2011) 0.85
Lte1, Cdc14 and MEN-controlled Cdk inactivation in yeast coordinate rDNA decompaction with late telophase progression. EMBO J (2009) 0.84
Roles for nuclear organization in the maintenance of genome stability. Epigenomics (2010) 0.82