Epigenetics in Saccharomyces cerevisiae.

Erasers of histone acetylation: the histone deacetylase enzymes. Cold Spring Harb Perspect Biol (2014) 1.18

Histone variants and epigenetics. Cold Spring Harb Perspect Biol (2015) 1.01

Dosage compensation in Drosophila. Cold Spring Harb Perspect Biol (2015) 1.01

Structural and functional coordination of DNA and histone methylation. Cold Spring Harb Perspect Biol (2014) 0.98

Neurospora crassa, a model system for epigenetics research. Cold Spring Harb Perspect Biol (2013) 0.96

Heritable capture of heterochromatin dynamics in Saccharomyces cerevisiae. Elife (2015) 0.92

The molecular topography of silenced chromatin in Saccharomyces cerevisiae. Genes Dev (2014) 0.89

The use of mouse models to study epigenetics. Cold Spring Harb Perspect Biol (2013) 0.80

The expanding epigenetic landscape of non-model organisms. J Exp Biol (2015) 0.79

Riches of phenotype computationally extracted from microbial colonies. Proc Natl Acad Sci U S A (2016) 0.78

Regulatory mechanisms that prevent re-initiation of DNA replication can be locally modulated at origins by nearby sequence elements. PLoS Genet (2014) 0.77

Direct interactions promote eviction of the Sir3 heterochromatin protein by the SWI/SNF chromatin remodeling enzyme. Proc Natl Acad Sci U S A (2014) 0.76

Modulations of SIR-nucleosome interactions of reconstructed yeast silent pre-heterochromatin by O-acetyl-ADP-ribose and magnesium. Mol Biol Cell (2016) 0.75

Evolution and Functional Trajectory of Sir1 in Gene Silencing. Mol Cell Biol (2016) 0.75

Different Toxicity Mechanisms for Citrinin and Ochratoxin A Revealed by Transcriptomic Analysis in Yeast. Toxins (Basel) (2016) 0.75

Cooperative stabilization of the SIR complex provides robust epigenetic memory in a model of SIR silencing in Saccharomyces cerevisiae. Epigenetics (2015) 0.75

A Matter of Scale and Dimensions: Chromatin of Chromosome Landmarks in the Fungi. Microbiol Spectr (2017) 0.75

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature (2000) 20.54

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev (1999) 14.43

Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription. Cell (1990) 12.50

Histone H4-K16 acetylation controls chromatin structure and protein interactions. Science (2006) 11.20

Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. Biochem Biophys Res Commun (2000) 9.09

Extrachromosomal rDNA circles--a cause of aging in yeast. Cell (1997) 8.68

SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast. Genes Dev (1997) 7.81

The establishment, inheritance, and function of silenced chromatin in Saccharomyces cerevisiae. Annu Rev Biochem (2003) 7.22

Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast. Cell (1995) 7.20

Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae. Cell (1991) 7.17

Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae. Genetics (1987) 7.05

Conserved histone variant H2A.Z protects euchromatin from the ectopic spread of silent heterochromatin. Cell (2003) 6.83

Dot1p modulates silencing in yeast by methylation of the nucleosome core. Cell (2002) 6.29

Characterization of a "silencer" in yeast: a DNA sequence with properties opposite to those of a transcriptional enhancer. Cell (1985) 6.23

An unusual form of transcriptional silencing in yeast ribosomal DNA. Genes Dev (1997) 6.00

A new role for a yeast transcriptional silencer gene, SIR2, in regulation of recombination in ribosomal DNA. Cell (1989) 5.48

Spreading of transcriptional repressor SIR3 from telomeric heterochromatin. Nature (1996) 5.37

Evidence that a complex of SIR proteins interacts with the silencer and telomere-binding protein RAP1. Genes Dev (1994) 5.21

A protein-counting mechanism for telomere length regulation in yeast. Science (1997) 4.79

Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast. Cell (1999) 4.71

Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage. Genes Dev (1993) 4.64

Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae. Nature (1997) 4.57

Identification of high-copy disruptors of telomeric silencing in Saccharomyces cerevisiae. Genetics (1998) 4.42

Microarray deacetylation maps determine genome-wide functions for yeast histone deacetylases. Cell (2002) 4.38

Sir2p and Sas2p opposingly regulate acetylation of yeast histone H4 lysine16 and spreading of heterochromatin. Nat Genet (2002) 4.36

A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery. Nature (2005) 4.33

A suppressor of mating-type locus mutations in Saccharomyces cerevisiae: evidence for and identification of cryptic mating-type loci. Genetics (1979) 4.30

A yeast silencer contains sequences that can promote autonomous plasmid replication and transcriptional activation. Cell (1987) 4.24

An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing. Cell (1999) 4.07

Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association. Genes Dev (2002) 4.07

Highly specific antibodies determine histone acetylation site usage in yeast heterochromatin and euchromatin. Mol Cell (2001) 4.06

Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose. Proc Natl Acad Sci U S A (2000) 3.94

Chromosomal gradient of histone acetylation established by Sas2p and Sir2p functions as a shield against gene silencing. Nat Genet (2002) 3.91

SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres. Cell (1993) 3.77

Genetic evidence for an interaction between SIR3 and histone H4 in the repression of the silent mating loci in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1990) 3.74

Efficient transcriptional silencing in Saccharomyces cerevisiae requires a heterochromatin histone acetylation pattern. Mol Cell Biol (1996) 3.72

Perinuclear localization of chromatin facilitates transcriptional silencing. Nature (1998) 3.68

Epigenetic inheritance of transcriptional states in S. cerevisiae. Cell (1989) 3.68

Localization of Sir2p: the nucleolus as a compartment for silent information regulators. EMBO J (1997) 3.55

Role of interactions between the origin recognition complex and SIR1 in transcriptional silencing. Nature (1996) 3.26

RNA polymerase III and RNA polymerase II promoter complexes are heterochromatin barriers in Saccharomyces cerevisiae. EMBO J (2001) 3.20

Sir2-independent life span extension by calorie restriction in yeast. PLoS Biol (2004) 3.20

RAP1 and telomere structure regulate telomere position effects in Saccharomyces cerevisiae. Genes Dev (1993) 3.18

Silencers and domains of generalized repression. Science (1994) 3.15

Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres. Curr Biol (1998) 3.13

Role of DNA replication in the repression of silent mating type loci in yeast. Nature (1984) 3.11

A method for genetically installing site-specific acetylation in recombinant histones defines the effects of H3 K56 acetylation. Mol Cell (2009) 3.11

Chromatin boundaries in budding yeast: the nuclear pore connection. Cell (2002) 3.09

Gene recruitment of the activated INO1 locus to the nuclear membrane. PLoS Biol (2004) 3.09

Steps in assembly of silent chromatin in yeast: Sir3-independent binding of a Sir2/Sir4 complex to silencers and role for Sir2-dependent deacetylation. Mol Cell Biol (2002) 2.93

C-terminal truncation of RAP1 results in the deregulation of telomere size, stability, and function in Saccharomyces cerevisiae. Mol Cell Biol (1992) 2.92

Live imaging of telomeres: yKu and Sir proteins define redundant telomere-anchoring pathways in yeast. Curr Biol (2002) 2.92

Cell cycle and checkpoint regulation of histone H3 K56 acetylation by Hst3 and Hst4. Mol Cell (2006) 2.91

Targeting of SIR1 protein establishes transcriptional silencing at HM loci and telomeres in yeast. Cell (1993) 2.91

Histone H3 amino terminus is required for telomeric and silent mating locus repression in yeast. Nature (1994) 2.87

Evidence for silencing compartments within the yeast nucleus: a role for telomere proximity and Sir protein concentration in silencer-mediated repression. Genes Dev (1996) 2.85

Ordered nucleation and spreading of silenced chromatin in Saccharomyces cerevisiae. Mol Biol Cell (2002) 2.80

Telomere-proximal DNA in Saccharomyces cerevisiae is refractory to methyltransferase activity in vivo. Proc Natl Acad Sci U S A (1992) 2.80

Limitations of silencing at native yeast telomeres. EMBO J (1999) 2.73

Silent information regulator protein complexes in Saccharomyces cerevisiae: a SIR2/SIR4 complex and evidence for a regulatory domain in SIR4 that inhibits its interaction with SIR3. Proc Natl Acad Sci U S A (1997) 2.52

Action of a RAP1 carboxy-terminal silencing domain reveals an underlying competition between HMR and telomeres in yeast. Genes Dev (1995) 2.50

Assembly of the SIR complex and its regulation by O-acetyl-ADP-ribose, a product of NAD-dependent histone deacetylation. Cell (2005) 2.47

Separation of silencing from perinuclear anchoring functions in yeast Ku80, Sir4 and Esc1 proteins. EMBO J (2004) 2.47

Cohabitation of insulators and silencing elements in yeast subtelomeric regions. EMBO J (1999) 2.45

Sir2 deacetylates histone H3 lysine 56 to regulate telomeric heterochromatin structure in yeast. Mol Cell (2007) 2.38

RAP-1 factor is necessary for DNA loop formation in vitro at the silent mating type locus HML. Cell (1989) 2.32

High-resolution structural analysis of chromatin at specific loci: Saccharomyces cerevisiae silent mating type locus HMLalpha. Mol Cell Biol (1998) 2.32

Histone H2B ubiquitylation controls processive methylation but not monomethylation by Dot1 and Set1. Mol Cell (2005) 2.32

Acetylation of the yeast histone H4 N terminus regulates its binding to heterochromatin protein SIR3. J Biol Chem (2001) 2.21

SIR2 regulates recombination between different rDNA repeats, but not recombination within individual rRNA genes in yeast. Cell (2004) 2.20

Rap1-Sir4 binding independent of other Sir, yKu, or histone interactions initiates the assembly of telomeric heterochromatin in yeast. Genes Dev (2002) 2.12

Interplay of chromatin modifiers on a short basic patch of histone H4 tail defines the boundary of telomeric heterochromatin. Mol Cell (2007) 2.07

Sir-mediated repression can occur independently of chromosomal and subnuclear contexts. Cell (2004) 2.04

DNA replication-independent silencing in S. cerevisiae. Science (2001) 2.03

Identification of a non-basic domain in the histone H4 N-terminus required for repression of the yeast silent mating loci. EMBO J (1992) 2.03

Role for perinuclear chromosome tethering in maintenance of genome stability. Nature (2008) 2.03

Establishment of transcriptional silencing in the absence of DNA replication. Science (2001) 1.93

Structural basis of silencing: Sir3 BAH domain in complex with a nucleosome at 3.0 Å resolution. Science (2011) 1.93

Role of the conserved Sir3-BAH domain in nucleosome binding and silent chromatin assembly. Mol Cell (2007) 1.89

Systematic identification of fragile sites via genome-wide location analysis of gamma-H2AX. Nat Struct Mol Biol (2010) 1.87

Heterochromatin formation involves changes in histone modifications over multiple cell generations. EMBO J (2005) 1.82

Position-effect variegation, heterochromatin formation, and gene silencing in Drosophila. Cold Spring Harb Perspect Biol (2013) 1.76

Structure of the coiled-coil dimerization motif of Sir4 and its interaction with Sir3. Structure (2003) 1.71

Yeast Ku protein plays a direct role in telomeric silencing and counteracts inhibition by rif proteins. Curr Biol (1999) 1.68

Esc1, a nuclear periphery protein required for Sir4-based plasmid anchoring and partitioning. Mol Cell Biol (2002) 1.68

Telomere anchoring at the nuclear periphery requires the budding yeast Sad1-UNC-84 domain protein Mps3. J Cell Biol (2007) 1.67

Yeast heterochromatin is a dynamic structure that requires silencers continuously. Genes Dev (2000) 1.64

Telomere looping permits gene activation by a downstream UAS in yeast. Nature (2001) 1.61

Reconstitution of yeast silent chromatin: multiple contact sites and O-AADPR binding load SIR complexes onto nucleosomes in vitro. Mol Cell (2009) 1.61

A charge-based interaction between histone H4 and Dot1 is required for H3K79 methylation and telomere silencing: identification of a new trans-histone pathway. Genes Dev (2007) 1.60

Yeast telomerase and the SUN domain protein Mps3 anchor telomeres and repress subtelomeric recombination. Genes Dev (2009) 1.59

The functional importance of telomere clustering: global changes in gene expression result from SIR factor dispersion. Genome Res (2009) 1.56

Ubp10/Dot4p regulates the persistence of ubiquitinated histone H2B: distinct roles in telomeric silencing and general chromatin. Mol Cell Biol (2005) 1.55

Cell-cycle control of the establishment of mating-type silencing in S. cerevisiae. Genes Dev (2002) 1.45

Regulation of subtelomeric silencing during stress response. Mol Cell (2002) 1.44

A nonhistone protein-protein interaction required for assembly of the SIR complex and silent chromatin. Mol Cell Biol (2005) 1.42

Specific repression of the yeast silent mating locus HMR by an adjacent telomere. Mol Cell Biol (1994) 1.42

An activation-independent role of transcription factors in insulator function. EMBO Rep (2001) 1.32

Mechanism of transcriptional silencing in yeast. Cell (2005) 1.31

Long-range communication between the silencers of HMR. Mol Cell Biol (2008) 1.28

Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair. Cell (2004) 4.76

Crosstalk between histone modifications during the DNA damage response. Trends Cell Biol (2009) 4.31

The nuclear envelope and transcriptional control. Nat Rev Genet (2007) 3.81

Automatic tracking of individual fluorescence particles: application to the study of chromosome dynamics. IEEE Trans Image Process (2005) 3.64

Gene regulation through nuclear organization. Nat Struct Mol Biol (2007) 3.44

Nuclear pore association confers optimal expression levels for an inducible yeast gene. Nature (2006) 3.39

DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1. EMBO J (2003) 3.15

Functional targeting of DNA damage to a nuclear pore-associated SUMO-dependent ubiquitin ligase. Science (2008) 3.09

Long-range compaction and flexibility of interphase chromatin in budding yeast analyzed by high-resolution imaging techniques. Proc Natl Acad Sci U S A (2004) 2.99

The histone code at DNA breaks: a guide to repair? Nat Rev Mol Cell Biol (2005) 2.97

Live imaging of telomeres: yKu and Sir proteins define redundant telomere-anchoring pathways in yeast. Curr Biol (2002) 2.92

Step-wise methylation of histone H3K9 positions heterochromatin at the nuclear periphery. Cell (2012) 2.67

Separation of silencing from perinuclear anchoring functions in yeast Ku80, Sir4 and Esc1 proteins. EMBO J (2004) 2.47

ORC and the intra-S-phase checkpoint: a threshold regulates Rad53p activation in S phase. Genes Dev (2002) 2.40

Distinct roles for SWR1 and INO80 chromatin remodeling complexes at chromosomal double-strand breaks. EMBO J (2007) 2.23

Heterochromatin protein 1: don't judge the book by its cover! Curr Opin Genet Dev (2006) 2.20

Replisome instability, fork collapse, and gross chromosomal rearrangements arise synergistically from Mec1 kinase and RecQ helicase mutations. Genes Dev (2005) 2.17

Chromosome looping in yeast: telomere pairing and coordinated movement reflect anchoring efficiency and territorial organization. J Cell Biol (2005) 2.16

The function of nuclear architecture: a genetic approach. Annu Rev Genet (2004) 2.06

Sir-mediated repression can occur independently of chromosomal and subnuclear contexts. Cell (2004) 2.04

The spatial dynamics of tissue-specific promoters during C. elegans development. Genes Dev (2010) 2.00

Mechanistically distinct roles for Sgs1p in checkpoint activation and replication fork maintenance. EMBO J (2004) 1.94

RecQ helicases: multiple roles in genome maintenance. Trends Cell Biol (2003) 1.91

Ino80 chromatin remodeling complex promotes recovery of stalled replication forks. Curr Biol (2008) 1.89

Increased mobility of double-strand breaks requires Mec1, Rad9 and the homologous recombination machinery. Nat Cell Biol (2012) 1.86

The nuclear envelope--a scaffold for silencing? Curr Opin Genet Dev (2009) 1.65

ATR/Mec1: coordinating fork stability and repair. Curr Opin Cell Biol (2009) 1.64

Reconstitution of yeast silent chromatin: multiple contact sites and O-AADPR binding load SIR complexes onto nucleosomes in vitro. Mol Cell (2009) 1.61

Yeast telomerase and the SUN domain protein Mps3 anchor telomeres and repress subtelomeric recombination. Genes Dev (2009) 1.59

Chromatin movement in the maintenance of genome stability. Cell (2013) 1.59

The functional importance of telomere clustering: global changes in gene expression result from SIR factor dispersion. Genome Res (2009) 1.56

An N-terminal domain of Dbf4p mediates interaction with both origin recognition complex (ORC) and Rad53p and can deregulate late origin firing. Proc Natl Acad Sci U S A (2002) 1.55

Temporal separation of replication and recombination requires the intra-S checkpoint. J Cell Biol (2005) 1.54

Controlled exchange of chromosomal arms reveals principles driving telomere interactions in yeast. Genome Res (2007) 1.48

The origin recognition complex functions in sister-chromatid cohesion in Saccharomyces cerevisiae. Cell (2007) 1.47

An EDMD mutation in C. elegans lamin blocks muscle-specific gene relocation and compromises muscle integrity. Curr Biol (2011) 1.43

The budding yeast nucleus. Cold Spring Harb Perspect Biol (2010) 1.43

Structure and function in the budding yeast nucleus. Genetics (2012) 1.37

Silent chromatin at the middle and ends: lessons from yeasts. EMBO J (2009) 1.36

Targeted INO80 enhances subnuclear chromatin movement and ectopic homologous recombination. Genes Dev (2012) 1.36

Myosin-like proteins 1 and 2 are not required for silencing or telomere anchoring, but act in the Tel1 pathway of telomere length control. J Struct Biol (2002) 1.34

Intracellular trafficking of yeast telomerase components. EMBO Rep (2002) 1.34

Replication foci dynamics: replication patterns are modulated by S-phase checkpoint kinases in fission yeast. EMBO J (2007) 1.30

The processing of double-strand breaks and binding of single-strand-binding proteins RPA and Rad51 modulate the formation of ATR-kinase foci in yeast. J Cell Sci (2007) 1.28

ATP-dependent chromatin remodeling and DNA double-strand break repair. Cell Cycle (2005) 1.27

Locking the genome: nuclear organization and cell fate. Curr Opin Genet Dev (2011) 1.22

Methods for visualizing chromatin dynamics in living yeast. Methods Enzymol (2004) 1.20

Nucleosome remodelers in double-strand break repair. Curr Opin Genet Dev (2013) 1.20

Regulation of nuclear positioning and dynamics of the silent mating type loci by the yeast Ku70/Ku80 complex. Mol Cell Biol (2008) 1.19

Actin-related proteins in the nucleus: life beyond chromatin remodelers. Curr Opin Cell Biol (2010) 1.18

Visualizing yeast chromosomes and nuclear architecture. Methods Enzymol (2010) 1.18

RecQ helicases: at the heart of genetic stability. FEBS Lett (2002) 1.17

The PIAS homologue Siz2 regulates perinuclear telomere position and telomerase activity in budding yeast. Nat Cell Biol (2011) 1.17

Nuclear organization and silencing: putting things in their place. Nat Cell Biol (2002) 1.14

Nuclear geometry and rapid mitosis ensure asymmetric episome segregation in yeast. Curr Biol (2010) 1.13

Promoter- and RNA polymerase II-dependent hsp-16 gene association with nuclear pores in Caenorhabditis elegans. J Cell Biol (2013) 1.13

Nuclear organization in genome stability: SUMO connections. Cell Res (2011) 1.13

Mechanisms of heterochromatin subnuclear localization. Trends Biochem Sci (2013) 1.12

Checkpoint kinases and the INO80 nucleosome remodeling complex enhance global chromatin mobility in response to DNA damage. Genes Dev (2013) 1.12

Modules for cloning-free chromatin tagging in Saccharomyces cerevisae. Yeast (2008) 1.12

TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks. Mol Cell (2013) 1.07

Multiple pathways tether telomeres and silent chromatin at the nuclear periphery: functional implications for sir-mediated repression. Novartis Found Symp (2005) 1.06

Multiple pathways for telomere tethering: functional implications of subnuclear position for heterochromatin formation. Biochim Biophys Acta (2004) 1.05

In and out of the replication factory. Cell (2006) 1.03

A homotrimer-heterotrimer switch in Sir2 structure differentiates rDNA and telomeric silencing. Mol Cell (2006) 1.03

SIR proteins and the assembly of silent chromatin in budding yeast. Annu Rev Genet (2013) 1.00

A dual role of H4K16 acetylation in the establishment of yeast silent chromatin. EMBO J (2011) 1.00

Subtelomeric factors antagonize telomere anchoring and Tel1-independent telomere length regulation. EMBO J (2006) 1.00

Ribosome biogenesis factors bind a nuclear envelope SUN domain protein to cluster yeast telomeres. EMBO J (2011) 0.99

An N-terminal acidic region of Sgs1 interacts with Rpa70 and recruits Rad53 kinase to stalled forks. EMBO J (2012) 0.99

Structural basis for the role of the Sir3 AAA+ domain in silencing: interaction with Sir4 and unmethylated histone H3K79. Genes Dev (2011) 0.98

Redundancy, insult-specific sensors and thresholds: unlocking the S-phase checkpoint response. Curr Opin Genet Dev (2004) 0.96

Actin-related protein Arp6 influences H2A.Z-dependent and -independent gene expression and links ribosomal protein genes to nuclear pores. PLoS Genet (2010) 0.94

Dot1 binding induces chromatin rearrangements by histone methylation-dependent and -independent mechanisms. Epigenetics Chromatin (2011) 0.91

Cell cycle-dependent phosphorylation of Rad53 kinase by Cdc5 and Cdc28 modulates checkpoint adaptation. Cell Cycle (2010) 0.90

Early initiation of a replication origin tethered at the nuclear periphery. J Cell Sci (2010) 0.89

RecQ helicases and genome stability: lessons from model organisms and human disease. Swiss Med Wkly (2002) 0.87

Posttranslational modifications of repair factors and histones in the cellular response to stalled replication forks. DNA Repair (Amst) (2009) 0.86

SIR-nucleosome interactions: structure-function relationships in yeast silent chromatin. Gene (2013) 0.85

Caenorhabditis elegans Heterochromatin protein 1 (HPL-2) links developmental plasticity, longevity and lipid metabolism. Genome Biol (2011) 0.85

Cohesin and the nucleolus constrain the mobility of spontaneous repair foci. EMBO Rep (2013) 0.85

γH2A is a component of yeast heterochromatin required for telomere elongation. Cell Cycle (2011) 0.85

Lte1, Cdc14 and MEN-controlled Cdk inactivation in yeast coordinate rDNA decompaction with late telophase progression. EMBO J (2009) 0.84

Roles for nuclear organization in the maintenance of genome stability. Epigenomics (2010) 0.82

Measuring limits of telomere movement on nuclear envelope. Biophys J (2005) 0.82

Dimerization of Sir3 via its C-terminal winged helix domain is essential for yeast heterochromatin formation. EMBO J (2013) 0.82

Regulating repression: roles for the sir4 N-terminus in linker DNA protection and stabilization of epigenetic states. PLoS Genet (2012) 0.81

A molecular dissection of nuclear function. Conference on the dynamic nucleus: questions and implications. EMBO Rep (2003) 0.81

The shelterin protein POT-1 anchors Caenorhabditis elegans telomeres through SUN-1 at the nuclear periphery. J Cell Biol (2013) 0.81

The formation and sequestration of heterochromatin during development: delivered on 7 September 2012 at the 37th FEBS Congress in Sevilla, Spain. FEBS J (2013) 0.80

DNA replication: Pif1 pulls the plug on stalled replication forks. Curr Biol (2012) 0.79

Repairing subtelomeric DSBs at the nuclear periphery. Trends Cell Biol (2006) 0.79

Modulation of drug sensitivity in yeast cells by the ATP-binding domain of human DNA topoisomerase IIalpha. Nucleic Acids Res (2003) 0.79

In vitro DNA replication assays in yeast extracts. Methods Enzymol (2002) 0.79

A Rad53 independent function of Rad9 becomes crucial for genome maintenance in the absence of the Recq helicase Sgs1. PLoS One (2013) 0.77

Visualizing the spatiotemporal dynamics of DNA damage in budding yeast. Methods Mol Biol (2015) 0.77

Epigenetics and disease: pharmaceutical opportunities. Preface. Prog Drug Res (2011) 0.76

Mitotic expression of Spo13 alters M-phase progression and nucleolar localization of Cdc14 in budding yeast. Genetics (2010) 0.75

Leap year: Rare day to highlight rare diseases. Nature (2012) 0.75