Ablation of the ID2 gene results in altered circadian feeding behavior, and sex-specific enhancement of insulin sensitivity and elevated glucose uptake in skeletal muscle and brown adipose tissue.

PubWeight™: 0.91‹?›

🔗 View Article (PMC 3759459)

Published in PLoS One on September 02, 2013

Authors

Deepa Mathew1, Peng Zhou, Cameron M Pywell, Daan R van der Veen, Jinping Shao, Yang Xi, Nicolle A Bonar, Alyssa D Hummel, Sarah Chapman, W Matthew Leevy, Giles E Duffield

Author Affiliations

1: Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, United States of America.

Articles cited by this

Identification and importance of brown adipose tissue in adult humans. N Engl J Med (2009) 20.57

Cold-activated brown adipose tissue in healthy men. N Engl J Med (2009) 17.58

Obesity and metabolic syndrome in circadian Clock mutant mice. Science (2005) 12.66

Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human. Cell (2012) 11.03

Mechanisms for insulin resistance: common threads and missing links. Cell (2012) 6.85

The meter of metabolism. Cell (2008) 5.71

Central and peripheral circadian clocks in mammals. Annu Rev Neurosci (2012) 4.73

Transcriptional coactivator PGC-1alpha integrates the mammalian clock and energy metabolism. Nature (2007) 4.54

Defective adipocyte differentiation in mice lacking the C/EBPbeta and/or C/EBPdelta gene. EMBO J (1997) 4.51

ID helix-loop-helix proteins in cell growth, differentiation and tumorigenesis. J Cell Sci (2000) 3.85

Crosstalk between components of circadian and metabolic cycles in mammals. Cell Metab (2011) 3.31

The role of C/EBP genes in adipocyte differentiation. J Biol Chem (1998) 3.30

Standard operating procedures for describing and performing metabolic tests of glucose homeostasis in mice. Dis Model Mech (2010) 3.27

Brain and muscle Arnt-like protein-1 (BMAL1), a component of the molecular clock, regulates adipogenesis. Proc Natl Acad Sci U S A (2005) 3.12

Characterization of peripheral circadian clocks in adipose tissues. Diabetes (2006) 3.06

Discovery of sexual dimorphisms in metabolic and genetic biomarkers. PLoS Genet (2011) 2.68

White to brown fat phenotypic switch induced by genetic and environmental activation of a hypothalamic-adipocyte axis. Cell Metab (2011) 2.68

Circadian rhythms, sleep, and metabolism. J Clin Invest (2011) 2.60

The critical role of metabolic pathways in aging. Diabetes (2012) 2.12

Identification of the circadian transcriptome in adult mouse skeletal muscle. Physiol Genomics (2007) 2.06

The circadian clock and pathology of the ageing brain. Nat Rev Neurosci (2012) 1.90

Strain screen and haplotype association mapping of wheel running in inbred mouse strains. J Appl Physiol (1985) (2010) 1.88

Adipocyte CREB promotes insulin resistance in obesity. Cell Metab (2009) 1.72

A role for Id2 in regulating photic entrainment of the mammalian circadian system. Curr Biol (2009) 1.70

Id and development. Oncogene (2001) 1.70

Gene expression profiles of nondiabetic and diabetic obese mice suggest a role of hepatic lipogenic capacity in diabetes susceptibility. Diabetes (2003) 1.61

Development of insulin resistance in mice lacking PGC-1α in adipose tissues. Proc Natl Acad Sci U S A (2012) 1.61

Determination of adipocyte size by computer image analysis. J Lipid Res (2002) 1.59

IGF-binding protein-2 protects against the development of obesity and insulin resistance. Diabetes (2007) 1.56

Inhibitor of differentiation-3 mediates high fat diet-induced visceral fat expansion. Arterioscler Thromb Vasc Biol (2011) 1.54

Gender aspects of the role of the metabolic syndrome as a risk factor for cardiovascular disease. Gend Med (2007) 1.48

CircaDB: a database of mammalian circadian gene expression profiles. Nucleic Acids Res (2012) 1.47

Increased tumor growth in mice with diet-induced obesity: impact of ovarian hormones. Endocrinology (2006) 1.44

Differential susceptibility to obesity between male, female and ovariectomized female mice. Nutr J (2009) 1.36

Quantitative assessment of brown adipose tissue metabolic activity and volume using 18F-FDG PET/CT and β3-adrenergic receptor activation. EJNMMI Res (2011) 1.31

Metabolic lessons from genetically lean mice. Annu Rev Nutr (2002) 1.30

Brown fat in humans: turning up the heat on obesity. Diabetes (2009) 1.28

Role of intramyocelluar lipids in human health. Trends Endocrinol Metab (2012) 1.27

Inhibitor of DNA binding 2 is a small molecule-inducible modulator of peroxisome proliferator-activated receptor-gamma expression and adipocyte differentiation. Mol Endocrinol (2008) 1.26

Age-related differences in skeletal muscle insulin signaling: the role of stress kinases and heat shock proteins. J Appl Physiol (1985) (2008) 1.22

Aging-sensitive cellular and molecular mechanisms associated with skeletal muscle hypertrophy. J Appl Physiol (1985) (2005) 1.18

Effect of adipocyte beta3-adrenergic receptor activation on the type 2 diabetic MKR mice. Am J Physiol Endocrinol Metab (2006) 1.14

Id3 prevents differentiation of preadipose cells. Mol Cell Biol (1997) 1.12

Circadian regulation of lipid mobilization in white adipose tissues. Diabetes (2013) 1.09

Functional antagonism between inhibitor of DNA binding (Id) and adipocyte determination and differentiation factor 1/sterol regulatory element-binding protein-1c (ADD1/SREBP-1c) trans-factors for the regulation of fatty acid synthase promoter in adipocytes. Biochem J (1999) 1.09

The clock gene, brain and muscle Arnt-like 1, regulates adipogenesis via Wnt signaling pathway. FASEB J (2012) 1.07

ID2 (inhibitor of DNA binding 2) is a rhythmically expressed transcriptional repressor required for circadian clock output in mouse liver. J Biol Chem (2009) 1.01

Metabolic impact of sex chromosomes. Adipocyte (2013) 1.00

Inhibition of Id1 augments insulin secretion and protects against high-fat diet-induced glucose intolerance. Diabetes (2011) 0.98

Ablation of the transcriptional regulator Id1 enhances energy expenditure, increases insulin sensitivity, and protects against age and diet induced insulin resistance, and hepatosteatosis. FASEB J (2011) 0.96

Regulation of Id2 expression by CCAAT/enhancer binding protein beta. Nucleic Acids Res (2005) 0.95

A diurnal rhythm in glucose uptake in brown adipose tissue revealed by in vivo PET-FDG imaging. Obesity (Silver Spring) (2012) 0.94

Increased myogenic repressor Id mRNA and protein levels in hindlimb muscles of aged rats. Am J Physiol Regul Integr Comp Physiol (2002) 0.94

Inhibitor of DNA binding 4 (ID4) regulation of adipocyte differentiation and adipose tissue formation in mice. J Biol Chem (2010) 0.94

Gender dimorphism in high-fat-diet-induced insulin resistance in skeletal muscle of aged rats. Cell Physiol Biochem (2008) 0.92

Effect of aging on insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of rats. Endocrinology (1996) 0.90

Characterization of a FGF19 variant with altered receptor specificity revealed a central role for FGFR1c in the regulation of glucose metabolism. PLoS One (2012) 0.89

IGF-binding protein-1 inhibits IGF effects on adipocyte function: implications for insulin-like actions at the adipocyte. J Endocrinol (2002) 0.89

The transcriptional repressor ID2 can interact with the canonical clock components CLOCK and BMAL1 and mediate inhibitory effects on mPer1 expression. J Biol Chem (2010) 0.88

Circadian rhythms, the molecular clock, and skeletal muscle. Curr Top Dev Biol (2011) 0.88

Glucose induces increases in levels of the transcriptional repressor Id2 via the hexosamine pathway. Am J Physiol Endocrinol Metab (2005) 0.86

Age-related decline of skeletal muscle insulin sensitivity in rats: effect of sex and muscle type. Rejuvenation Res (2011) 0.86

The serum glucose response to acute stress is sensitive to the intensity of the stressor and to habituation. Psychoneuroendocrinology (1990) 0.82

A 24-hour temporal profile of in vivo brain and heart pet imaging reveals a nocturnal peak in brain 18F-fluorodeoxyglucose uptake. PLoS One (2012) 0.82

Thiazolidinediones, a class of anti-diabetic drugs, inhibit Id2 expression through a PPARgamma-independent pathway in human aortic smooth muscle cells. Cell Mol Life Sci (2003) 0.81

Microarray analysis of thioacetamide-treated type 1 diabetic rats. Toxicol Appl Pharmacol (2005) 0.80

Aging well with a little wine and a good clock. Cell (2013) 0.79

Articles by these authors

The Medicago genome provides insight into the evolution of rhizobial symbioses. Nature (2011) 4.94

Crown ethers: sensors for ions and molecular scaffolds for materials and biological models. Chem Rev (2004) 3.23

Comparative analysis of bat genomes provides insight into the evolution of flight and immunity. Science (2012) 2.29

Regulation of apoptosis and differentiation by p53 in human embryonic stem cells. J Biol Chem (2006) 1.99

A three-channel microfluidic device for generating static linear gradients and its application to the quantitative analysis of bacterial chemotaxis. Lab Chip (2005) 1.85

Metagenomic analysis of viruses from bat fecal samples reveals many novel viruses in insectivorous bats in China. J Virol (2012) 1.70

Storable, thermally activated, near-infrared chemiluminescent dyes and dye-stained microparticles for optical imaging. Nat Chem (2010) 1.70

Intermolecular failure of L-type Ca2+ channel and ryanodine receptor signaling in hypertrophy. PLoS Biol (2007) 1.70

Atomic layer deposition of high-density Pt nanodots on Al2O3 film using (MeCp)Pt(Me)3 and O2 precursors for nonvolatile memory applications. Nanoscale Res Lett (2013) 1.65

Globally diverse Toxoplasma gondii isolates comprise six major clades originating from a small number of distinct ancestral lineages. Proc Natl Acad Sci U S A (2012) 1.64

Hepatic DNA deposition drives drug-induced liver injury and inflammation in mice. Hepatology (2014) 1.60

High-performance bilayer flexible resistive random access memory based on low-temperature thermal atomic layer deposition. Nanoscale Res Lett (2013) 1.51

Squaraine rotaxanes: superior substitutes for Cy-5 in molecular probes for near-infrared fluorescence cell imaging. Angew Chem Int Ed Engl (2007) 1.47

Whole-genome nucleotide diversity, recombination, and linkage disequilibrium in the model legume Medicago truncatula. Proc Natl Acad Sci U S A (2011) 1.46

Long non-coding RNA expression profile in human gastric cancer and its clinical significances. J Transl Med (2013) 1.43

The frequency gene is required for temperature-dependent regulation of many clock-controlled genes in Neurospora crassa. Genetics (2003) 1.42

Notch activation promotes cell proliferation and the formation of neural stem cell-like colonies in human glioma cells. Mol Cell Biochem (2007) 1.41

Genome-wide profiling of diel and circadian gene expression in the malaria vector Anopheles gambiae. Proc Natl Acad Sci U S A (2011) 1.39

Host range, prevalence, and genetic diversity of adenoviruses in bats. J Virol (2010) 1.39

c-MYC-regulated miR-23a/24-2/27a cluster promotes mammary carcinoma cell invasion and hepatic metastasis by targeting Sprouty2. J Biol Chem (2013) 1.37

Optical imaging of mammary and prostate tumors in living animals using a synthetic near infrared zinc(II)-dipicolylamine probe for anionic cell surfaces. J Am Chem Soc (2010) 1.34

Doc2 supports spontaneous synaptic transmission by a Ca(2+)-independent mechanism. Neuron (2011) 1.33

Synaptotagmin-1 and synaptotagmin-7 trigger synchronous and asynchronous phases of neurotransmitter release. Neuron (2013) 1.32

Psychologic predictors of cancer information avoidance among older adults: the role of cancer fear and fatalism. Cancer Epidemiol Biomarkers Prev (2008) 1.32

Positive regulation of hepatic miR-122 expression by HNF4α. J Hepatol (2011) 1.31

Mistimed sleep disrupts circadian regulation of the human transcriptome. Proc Natl Acad Sci U S A (2014) 1.30

2-step optimization of the extraction and subsequent physical properties of channel catfish (Ictalurus punctatus) skin gelatin. J Food Sci (2007) 1.29

Full-length genome sequences of two SARS-like coronaviruses in horseshoe bats and genetic variation analysis. J Gen Virol (2006) 1.28

A semi-floating gate transistor for low-voltage ultrafast memory and sensing operation. Science (2013) 1.28

The spectral composition of evening light and individual differences in the suppression of melatonin and delay of sleep in humans. J Pineal Res (2011) 1.28

miR-24-3p and miR-27a-3p promote cell proliferation in glioma cells via cooperative regulation of MXI1. Int J Oncol (2012) 1.26

Difference in receptor usage between severe acute respiratory syndrome (SARS) coronavirus and SARS-like coronavirus of bat origin. J Virol (2007) 1.25

First report of genotyping of Toxoplasma gondii isolates from wild birds in China. J Parasitol (2012) 1.22

Intraspecies diversity of SARS-like coronaviruses in Rhinolophus sinicus and its implications for the origin of SARS coronaviruses in humans. J Gen Virol (2009) 1.16

Spectral unmixing of multicolored bioluminescence emitted from heterogeneous biological sources. Anal Chem (2006) 1.16

Enhanced photocatalytic CO₂-reduction activity of anatase TiO₂ by coexposed {001} and {101} facets. J Am Chem Soc (2014) 1.15

Neurotransmitter receptors and cognitive dysfunction in Alzheimer's disease and Parkinson's disease. Prog Neurobiol (2012) 1.12

Patterns of above- and belowground biomass allocation in China's grasslands: evidence from individual-level observations. Sci China Life Sci (2010) 1.11

Expression of TGF, matrix metalloproteinases, and tissue inhibitors in Chinese chronic rhinosinusitis. J Allergy Clin Immunol (2010) 1.11

Functional, synthetic organic chemical models of cellular ion channels. Bioorg Med Chem (2004) 1.10

Photodynamic therapy for acute central serous chorioretinopathy: the safe effective lowest dose of verteporfin. Retina (2009) 1.09

Candidate genes and genetic architecture of symbiotic and agronomic traits revealed by whole-genome, sequence-based association genetics in Medicago truncatula. PLoS One (2013) 1.08

microRNAs in cancer: from bench to bedside. Adv Cancer Res (2010) 1.08

Mir-24 regulates junctophilin-2 expression in cardiomyocytes. Circ Res (2012) 1.07

Temporal-spatial variation and controls of soil respiration in different primary succession stages on glacier forehead in Gongga Mountain, China. PLoS One (2012) 1.05

Comparison of clock gene expression in SCN, retina, heart, and liver of mice. Biochem Biophys Res Commun (2006) 1.05

Identification of an RNA silencing suppressor from a plant double-stranded RNA virus. J Virol (2005) 1.03

Modulation in current density of metal/n-SiC contact by inserting Al2O3 interfacial layer. Nanoscale Res Lett (2013) 1.02

Molecular characterisation of Toll-like receptors in the black flying fox Pteropus alecto. Dev Comp Immunol (2010) 1.01

Optical imaging of bacterial infection in living mice using deep-red fluorescent squaraine rotaxane probes. Bioconjug Chem (2010) 1.01

ID2 (inhibitor of DNA binding 2) is a rhythmically expressed transcriptional repressor required for circadian clock output in mouse liver. J Biol Chem (2009) 1.01

HMGA1 is induced by Wnt/beta-catenin pathway and maintains cell proliferation in gastric cancer. Am J Pathol (2009) 1.01

MicroRNA-424-5p suppresses the expression of SOCS6 in pancreatic cancer. Pathol Oncol Res (2013) 1.00

Soluble EphB4 inhibition of PDGF-induced RPE migration in vitro. Invest Ophthalmol Vis Sci (2009) 1.00

Extensive circadian and light regulation of the transcriptome in the malaria mosquito Anopheles gambiae. BMC Genomics (2013) 1.00

Fine-scale population recombination rates, hotspots, and correlates of recombination in the Medicago truncatula genome. Genome Biol Evol (2012) 0.99

Zinc(II) coordination complexes as membrane-active fluorescent probes and antibiotics. Chembiochem (2008) 0.99

Growth inhibitory effects of three miR-129 family members on gastric cancer. Gene (2013) 0.98

Cell-permeable GPNA with appropriate backbone stereochemistry and spacing binds sequence-specifically to RNA. Chem Commun (Camb) (2004) 0.98

Imaging and analysis of Pseudomonas aeruginosa swarming and rhamnolipid production. Appl Environ Microbiol (2011) 0.98

Proteomics informed by transcriptomics reveals Hendra virus sensitizes bat cells to TRAIL-mediated apoptosis. Genome Biol (2014) 0.98

A novel multifunctional α-amylase from the thermophilic fungus Malbranchea cinnamomea: biochemical characterization and three-dimensional structure. Appl Biochem Biotechnol (2013) 0.97

Quality and acceptability of patient-reported outcome measures used in chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME): a systematic review. Qual Life Res (2011) 0.97

The CRTC1-SIK1 pathway regulates entrainment of the circadian clock. Cell (2013) 0.97

Total parathyroidectomy with trace amounts of parathyroid tissue autotransplantation as the treatment of choice for secondary hyperparathyroidism: a single-center experience. BMC Surg (2014) 0.97

In vivo optical imaging of acute cell death using a near-infrared fluorescent zinc-dipicolylamine probe. Mol Pharm (2011) 0.95

Antioxidant enzymes mediate survival of breast cancer cells deprived of extracellular matrix. Cancer Res (2013) 0.95

Genomic signature of adaptation to climate in Medicago truncatula. Genetics (2014) 0.95

A diurnal rhythm in glucose uptake in brown adipose tissue revealed by in vivo PET-FDG imaging. Obesity (Silver Spring) (2012) 0.94

Calcium influx through If channels in rat ventricular myocytes. Am J Physiol Cell Physiol (2006) 0.93

Multiple functions of Rice dwarf phytoreovirus Pns10 in suppressing systemic RNA silencing. J Virol (2010) 0.93

Phylogenetic signal variation in the genomes of Medicago (Fabaceae). Syst Biol (2013) 0.93

Screening and identification of B cell epitopes of structural proteins of foot-and-mouth disease virus serotype Asia1. Vet Microbiol (2009) 0.93

Strain- and sex-specific differences in daily flight activity and the circadian clock of Anopheles gambiae mosquitoes. J Insect Physiol (2012) 0.92

FXR ligands protect against hepatocellular inflammation via SOCS3 induction. Cell Signal (2012) 0.92

Prevalence and genetic diversity of adeno-associated viruses in bats from China. J Gen Virol (2010) 0.92

Daily rhythms in antennal protein and olfactory sensitivity in the malaria mosquito Anopheles gambiae. Sci Rep (2013) 0.92

Simvastatin induces neuroprotection in 6-OHDA-lesioned PC12 via the PI3K/AKT/caspase 3 pathway and anti-inflammatory responses. CNS Neurosci Ther (2012) 0.91

Recent Advances in Synthetic Membrane Transporters. Supramol Chem (2007) 0.91

A synthetic, chloride-selective channel that alters chloride transport in epithelial cells. Chem Commun (Camb) (2005) 0.91

New understanding of the difference of photocatalytic activity among anatase, rutile and brookite TiO2. Phys Chem Chem Phys (2014) 0.90

High-level expression of extracellular secretion of a β-xylosidase gene from Paecilomyces thermophila in Escherichia coli. Bioresour Technol (2010) 0.90

Molecular mechanisms of antibacterial and antitumor actions of designed surfactant-like peptides. Biomaterials (2011) 0.90

Altered sleep and behavioral activity phenotypes in PER3-deficient mice. Am J Physiol Regul Integr Comp Physiol (2011) 0.90

Genetic and functional dissection of ARMS2 in age-related macular degeneration and polypoidal choroidal vasculopathy. PLoS One (2013) 0.90

Epigenetic regulation of αA-crystallin in high myopia-induced dark nuclear cataract. PLoS One (2013) 0.89

Whole genome association study in a homogenous population in Shandong peninsula of China reveals JARID2 as a susceptibility gene for schizophrenia. J Biomed Biotechnol (2009) 0.89

Transperitoneal mini-laparoscopic pyeloplasty and concomitant ureteroscopy-assisted pyelolithotomy for ureteropelvic junction obstruction complicated by renal caliceal stones. PLoS One (2013) 0.89

The Influence of Varied Amide Bond Positions on Hydraphile Ion Channel Activity. New J Chem (2006) 0.89

Cardiac atrial circadian rhythms in PERIOD2::LUCIFERASE and per1:luc mice: amplitude and phase responses to glucocorticoid signaling and medium treatment. PLoS One (2012) 0.89

Application of tripolar concentric electrodes and prefeature selection algorithm for brain-computer interface. IEEE Trans Neural Syst Rehabil Eng (2008) 0.89

Prevalence and genetic characterization of Cryptosporidium in yaks in Qinghai Province of China. PLoS One (2013) 0.88

Effects of polyols on the stability of whey proteins in intermediate-moisture food model systems. J Agric Food Chem (2009) 0.88