Published in J Clin Invest on June 01, 2011
Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β. Nature (2012) 4.15
Adverse metabolic consequences in humans of prolonged sleep restriction combined with circadian disruption. Sci Transl Med (2012) 3.08
Rev-erbα and Rev-erbβ coordinately protect the circadian clock and normal metabolic function. Genes Dev (2012) 2.83
FGF21 regulates metabolism and circadian behavior by acting on the nervous system. Nat Med (2013) 2.20
Genome-wide RNA polymerase II profiles and RNA accumulation reveal kinetics of transcription and associated epigenetic changes during diurnal cycles. PLoS Biol (2012) 2.12
Effects of diurnal variation of gut microbes and high-fat feeding on host circadian clock function and metabolism. Cell Host Microbe (2015) 2.05
The human circadian metabolome. Proc Natl Acad Sci U S A (2012) 2.04
The number of x chromosomes causes sex differences in adiposity in mice. PLoS Genet (2012) 2.02
How might circadian rhythms control mood? Let me count the ways... Biol Psychiatry (2013) 1.95
Effects of insufficient sleep on circadian rhythmicity and expression amplitude of the human blood transcriptome. Proc Natl Acad Sci U S A (2013) 1.94
Clocks, metabolism, and the epigenome. Mol Cell (2012) 1.84
Danger signalling during cancer cell death: origins, plasticity and regulation. Cell Death Differ (2013) 1.39
The circadian clock in cancer development and therapy. Prog Mol Biol Transl Sci (2013) 1.28
Digging deeper into obesity. J Clin Invest (2011) 1.23
Effect of sleep deprivation on the human metabolome. Proc Natl Acad Sci U S A (2014) 1.22
Chronotype is independently associated with glycemic control in type 2 diabetes. Diabetes Care (2013) 1.14
Sleep supports selective retention of associative memories based on relevance for future utilization. PLoS One (2012) 1.11
Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21. Proc Natl Acad Sci U S A (2014) 1.10
Action of RORs and their ligands in (patho)physiology. Trends Endocrinol Metab (2012) 1.08
The circadian clock: a framework linking metabolism, epigenetics and neuronal function. Nat Rev Neurosci (2012) 1.08
Childhood obesity and sleep: relatives, partners, or both?--a critical perspective on the evidence. Ann N Y Acad Sci (2012) 1.07
Circadian clocks and metabolism. Handb Exp Pharmacol (2013) 1.07
Smith-Magenis syndrome results in disruption of CLOCK gene transcription and reveals an integral role for RAI1 in the maintenance of circadian rhythmicity. Am J Hum Genet (2012) 1.04
Metabolic impact of sex chromosomes. Adipocyte (2013) 1.00
Nutrient sensing and the circadian clock. Trends Endocrinol Metab (2012) 0.98
Laser-capture microdissection and transcriptional profiling of the dorsomedial nucleus of the hypothalamus. J Comp Neurol (2012) 0.95
Metabolic compensation of the Neurospora clock by a glucose-dependent feedback of the circadian repressor CSP1 on the core oscillator. Genes Dev (2012) 0.95
Behavioral changes and dopaminergic dysregulation in mice lacking the nuclear receptor Rev-erbα. Mol Endocrinol (2014) 0.92
The effects of short-term overfeeding on energy expenditure and nutrient oxidation in obesity-prone and obesity-resistant individuals. Int J Obes (Lond) (2012) 0.92
Meal frequency patterns determine the phase of mouse peripheral circadian clocks. Sci Rep (2012) 0.92
Circadian Dysfunction Induces Leptin Resistance in Mice. Cell Metab (2015) 0.92
Controlling complexity: the clinical relevance of mouse complex genetics. Eur J Hum Genet (2013) 0.92
Photoreceptor phagocytosis is mediated by phosphoinositide signaling. FASEB J (2013) 0.91
Preliminary evidence for obesity and elevations in fasting insulin mediating associations between cortisol awakening response and hippocampal volumes and frontal atrophy. Psychoneuroendocrinology (2012) 0.91
Circadian epigenomic remodeling and hepatic lipogenesis: lessons from HDAC3. Cold Spring Harb Symp Quant Biol (2011) 0.90
Period2 gene mutant mice show compromised insulin-mediated endothelial nitric oxide release and altered glucose homeostasis. Front Physiol (2012) 0.89
A Framework for Quantitative Modeling of Neural Circuits Involved in Sleep-to-Wake Transition. Front Neurol (2015) 0.88
Mitochondrial fatty acid oxidation in obesity. Antioxid Redox Signal (2012) 0.88
Human peripheral clocks: applications for studying circadian phenotypes in physiology and pathophysiology. Front Neurol (2015) 0.88
RelB: an outlier in leukocyte biology. J Leukoc Biol (2013) 0.88
The circadian clock in oral health and diseases. J Dent Res (2013) 0.86
Circadian metabolism in the light of evolution. Endocr Rev (2015) 0.86
PER2 promotes glucose storage to liver glycogen during feeding and acute fasting by inducing Gys2 PTG and G L expression. Mol Metab (2013) 0.86
Energy metabolism and rheumatic diseases: from cell to organism. Arthritis Res Ther (2012) 0.85
Estrogens prevent metabolic dysfunctions induced by circadian disruptions in female mice. Endocrinology (2015) 0.84
Melanocortin-3 receptors and metabolic homeostasis. Prog Mol Biol Transl Sci (2013) 0.84
Morningness-eveningness questionnaire score correlates with glycated hemoglobin in middle-aged male workers with type 2 diabetes mellitus. J Diabetes Investig (2013) 0.83
REV-ERB-erating nuclear receptor functions in circadian metabolism and physiology. Cell Res (2012) 0.83
Analysis of a gene regulatory cascade mediating circadian rhythm in zebrafish. PLoS Comput Biol (2013) 0.83
A Circadian Clock Gene, Cry, Affects Heart Morphogenesis and Function in Drosophila as Revealed by Optical Coherence Microscopy. PLoS One (2015) 0.83
The underlying interactome of childhood obesity: the potential role of sleep. Child Obes (2012) 0.82
Manipulating the circadian and sleep cycles to protect against metabolic disease. Front Endocrinol (Lausanne) (2015) 0.82
Quantitative peptidomics for discovery of circadian-related peptides from the rat suprachiasmatic nucleus. J Proteome Res (2013) 0.81
Stress in obesity and associated metabolic and cardiovascular disorders. Scientifica (Cairo) (2012) 0.81
Sleep-wake cycle irregularities in type 2 diabetics. Diabetol Metab Syndr (2012) 0.81
Clock genes, pancreatic function, and diabetes. Trends Mol Med (2014) 0.80
Circadian rhythmicity as a predictor of weight-loss effectiveness. Int J Obes (Lond) (2013) 0.80
A metabolic-transcriptional network links sleep and cellular energetics in the brain. Pflugers Arch (2011) 0.80
Palmitate Inhibits SIRT1-Dependent BMAL1/CLOCK Interaction and Disrupts Circadian Gene Oscillations in Hepatocytes. PLoS One (2015) 0.80
Clock genes show circadian rhythms in salivary glands. J Dent Res (2012) 0.80
Aging and sleep deprivation induce the unfolded protein response in the pancreas: implications for metabolism. Aging Cell (2013) 0.80
Genetics and epigenetics of circadian rhythms and their potential roles in neuropsychiatric disorders. Neurosci Bull (2015) 0.79
Comparative Circadian Metabolomics Reveal Differential Effects of Nutritional Challenge in the Serum and Liver. J Biol Chem (2015) 0.79
Geographical distribution of adolescent body height with respect to effective day length in Japan: an ecological analysis. PLoS One (2012) 0.79
Altered circadian rhythm and metabolic gene profile in rats subjected to advanced light phase shifts. PLoS One (2015) 0.79
Modelling and analysis of the feeding regimen induced entrainment of hepatocyte circadian oscillators using petri nets. PLoS One (2015) 0.79
Cortical-subcortical interactions in hypersomnia disorders: mechanisms underlying cognitive and behavioral aspects of the sleep-wake cycle. Front Neurol (2014) 0.79
Circadian regulation of Tshb gene expression by Rev-Erbα (NR1D1) and nuclear corepressor 1 (NCOR1). J Biol Chem (2014) 0.79
From blue light to clock genes in zebrafish ZEM-2S cells. PLoS One (2014) 0.79
Optical Coherence Tomography for Brain Imaging and Developmental Biology. IEEE J Sel Top Quantum Electron (2015) 0.78
Sleep physiology, abnormal States, and therapeutic interventions. Ochsner J (2012) 0.78
Genetic variation in the NOC gene is associated with body mass index in Chinese subjects. PLoS One (2013) 0.78
Effect of summer daylight exposure and genetic background on growth in growth hormone-deficient children. Pharmacogenomics J (2015) 0.78
The Effects of Leptin on Breastfeeding Behaviour. Int J Environ Res Public Health (2015) 0.78
Season of birth is associated with adult body mass index in patients with bipolar disorder. Chronobiol Int (2013) 0.78
Novel putative mechanisms to link circadian clocks to healthy aging. J Neural Transm (Vienna) (2013) 0.77
Synchronizing an aging brain: can entraining circadian clocks by food slow Alzheimer's disease? Front Aging Neurosci (2014) 0.77
Association between actigraphic sleep metrics and body composition. Ann Epidemiol (2015) 0.77
Reciprocal interactions between circadian clocks and aging. Mamm Genome (2016) 0.77
Systems biology and innate immunity. J Innate Immun (2013) 0.77
Is the timing of caloric intake associated with variation in diet-induced thermogenesis and in the metabolic pattern? A randomized cross-over study. Int J Obes (Lond) (2015) 0.76
Orexin signaling regulates both the hippocampal clock and the circadian oscillation of Alzheimer's disease-risk genes. Sci Rep (2016) 0.76
Adjunctive agomelatine therapy in the treatment of acute bipolar II depression: a preliminary open label study. Neuropsychiatr Dis Treat (2013) 0.76
Effects of ovarian hormones on internal circadian organization in rats. Biol Reprod (2013) 0.76
Opening the Debate: How to Fulfill the Need for Physicians' Training in Circadian-Related Topics in a Full Medical School Curriculum. J Circadian Rhythms (2015) 0.76
Chronopharmacodynamics of drugs in toxicological aspects: A short review for clinical pharmacists and pharmacy practitioners. J Res Pharm Pract (2012) 0.76
In vivo veritas, in vitro artificia. Trends Mol Med (2012) 0.76
Gene expression in the liver of female, but not male mice treated with rapamycin resembles changes observed under dietary restriction. Springerplus (2015) 0.76
Glucose-Raising Polymorphisms in the Human Clock Gene Cryptochrome 2 (CRY2) Affect Hepatic Lipid Content. PLoS One (2016) 0.75
Daily rhythms of glycerophospholipid synthesis in fibroblast cultures involve differential enzyme contributions. J Lipid Res (2013) 0.75
Metabolomics Analysis Revealed Distinct Cyclic Changes of Metabolites Altered by Chronic Ethanol-Plus-Binge and Shp Deficiency. Alcohol Clin Exp Res (2016) 0.75
Prader-Willi syndrome, excessive daytime sleepiness, and narcoleptic symptoms: a case report. J Med Case Rep (2014) 0.75
The effects of time-restricted feeding on lipid metabolism and adiposity. Adipocyte (2015) 0.75
Differences in circadian time structure of diastolic blood pressure between diabetes mellitus and essential hypertension. Diabetol Metab Syndr (2012) 0.75
Role of a circadian-relevant gene NR1D1 in brain development: possible involvement in the pathophysiology of autism spectrum disorders. Sci Rep (2017) 0.75
Chronotherapy: Intuitive, Sound, Founded…But Not Broadly Applied. Drugs (2016) 0.75
Obesity, the deadly quartet and the contribution of the neglected daily organ rest - a new dimension of un-health and its prevention. Hepatobiliary Surg Nutr (2015) 0.75
Evolving roles of circadian rhythms in liver homeostasis and pathology. Oncotarget (2016) 0.75
Sex differences in obesity: X chromosome dosage as a risk factor for increased food intake, adiposity and co-morbidities. Physiol Behav (2017) 0.75
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature (2005) 18.41
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Impact of sleep debt on metabolic and endocrine function. Lancet (1999) 14.89
Coordinated transcription of key pathways in the mouse by the circadian clock. Cell (2002) 14.07
AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. Cell Metab (2005) 13.91
Obesity and metabolic syndrome in circadian Clock mutant mice. Science (2005) 12.66
PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues. Proc Natl Acad Sci U S A (2004) 12.43
Central nervous system control of food intake and body weight. Nature (2006) 11.89
Metabolic control through the PGC-1 family of transcription coactivators. Cell Metab (2005) 11.66
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science (2004) 11.39
Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index. PLoS Med (2004) 11.17
A serum shock induces circadian gene expression in mammalian tissue culture cells. Cell (1998) 10.92
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity. Nature (2009) 10.59
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma. Nature (2004) 10.32
Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation. Cell (1999) 9.84
Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase. Nature (2002) 8.77
Clock mutants of Drosophila melanogaster. Proc Natl Acad Sci U S A (1971) 8.63
Resetting central and peripheral circadian oscillators in transgenic rats. Science (2000) 8.63
Hypothalamic mTOR signaling regulates food intake. Science (2006) 8.62
Hypothalamic regulation of sleep and circadian rhythms. Nature (2005) 8.23
Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus. Genes Dev (2000) 8.19
The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene. Cell (1999) 7.99
Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior. Science (1994) 7.83
Positional cloning of the mouse circadian clock gene. Cell (1997) 7.79
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus. Nature (2004) 7.64
Entrainment of the circadian clock in the liver by feeding. Science (2001) 7.09
A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains. Nat Med (2000) 7.05
Reduced number of hypocretin neurons in human narcolepsy. Neuron (2000) 6.94
Circadian integration of metabolism and energetics. Science (2010) 6.86
BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis. PLoS Biol (2004) 6.72
Adverse metabolic and cardiovascular consequences of circadian misalignment. Proc Natl Acad Sci U S A (2009) 6.67
Anatomy and regulation of the central melanocortin system. Nat Neurosci (2005) 6.60
Resetting of circadian time in peripheral tissues by glucocorticoid signaling. Science (2000) 6.55
The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control. Cell (2008) 6.44
System-driven and oscillator-dependent circadian transcription in mice with a conditionally active liver clock. PLoS Biol (2007) 6.23
An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome. Science (2001) 6.07
Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes. Nature (2010) 5.97
Physiological significance of a peripheral tissue circadian clock. Proc Natl Acad Sci U S A (2008) 5.94
A functional genomics strategy reveals Rora as a component of the mammalian circadian clock. Neuron (2004) 5.71
SIRT1 regulates circadian clock gene expression through PER2 deacetylation. Cell (2008) 5.68
Functional identification of the mouse circadian Clock gene by transgenic BAC rescue. Cell (1997) 5.51
Nuclear receptor expression links the circadian clock to metabolism. Cell (2006) 5.43
Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1. Science (2009) 5.35
Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis. Science (2009) 5.30
Regulation of clock and NPAS2 DNA binding by the redox state of NAD cofactors. Science (2001) 5.03
The need to feed: homeostatic and hedonic control of eating. Neuron (2002) 4.99
High-fat diet disrupts behavioral and molecular circadian rhythms in mice. Cell Metab (2007) 4.93
Temperature as a universal resetting cue for mammalian circadian oscillators. Science (2010) 4.85
AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation. Science (2009) 4.72
Rev-erbalpha, a heme sensor that coordinates metabolic and circadian pathways. Science (2007) 4.68
Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors. Science (2000) 4.62
Nutrient availability regulates SIRT1 through a forkhead-dependent pathway. Science (2004) 4.61
Transcriptional coactivator PGC-1alpha integrates the mammalian clock and energy metabolism. Nature (2007) 4.54
The neural circuit of orexin (hypocretin): maintaining sleep and wakefulness. Nat Rev Neurosci (2007) 4.46
Functional consequences of a CKIdelta mutation causing familial advanced sleep phase syndrome. Nature (2005) 4.39
Effects of poor and short sleep on glucose metabolism and obesity risk. Nat Rev Endocrinol (2009) 4.09
cAMP-dependent signaling as a core component of the mammalian circadian pacemaker. Science (2008) 4.02
Brain reward circuitry: insights from unsensed incentives. Neuron (2002) 3.98
PPAR gamma and human metabolic disease. J Clin Invest (2006) 3.83
Altered patterns of sleep and behavioral adaptability in NPAS2-deficient mice. Science (2003) 3.70
Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasis. J Clin Invest (2006) 3.48
Circadian timing of food intake contributes to weight gain. Obesity (Silver Spring) (2009) 3.44
Circadian orchestration of the hepatic proteome. Curr Biol (2006) 3.37
AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons. J Clin Invest (2007) 3.32
The dorsomedial hypothalamic nucleus is critical for the expression of food-entrainable circadian rhythms. Nat Neurosci (2006) 3.29
Familial advanced sleep-phase syndrome: A short-period circadian rhythm variant in humans. Nat Med (1999) 3.27
Brain and muscle Arnt-like protein-1 (BMAL1), a component of the molecular clock, regulates adipogenesis. Proc Natl Acad Sci U S A (2005) 3.12
Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression. Proc Natl Acad Sci U S A (2009) 2.98
REV-ERBalpha participates in circadian SREBP signaling and bile acid homeostasis. PLoS Biol (2009) 2.76
Behavioral and neuroendocrine characteristics of the night-eating syndrome. JAMA (1999) 2.71
Hypothalamic sensing of fatty acids. Nat Neurosci (2005) 2.67
Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis. Nat Med (2010) 2.65
Neurobiology of feeding and energy expenditure. Annu Rev Neurosci (2007) 2.64
Afferents to the orexin neurons of the rat brain. J Comp Neurol (2006) 2.57
The "other" circadian system: food as a Zeitgeber. J Biol Rhythms (2002) 2.57
Persistence of a behavioral food-anticipatory circadian rhythm following dorsomedial hypothalamic ablation in rats. Am J Physiol Regul Integr Comp Physiol (2006) 2.54
Dissecting the functions of the mammalian clock protein BMAL1 by tissue-specific rescue in mice. Science (2006) 2.41
Roles of circadian rhythmicity and sleep in human glucose regulation. Endocr Rev (1997) 2.39
Insufficient sleep undermines dietary efforts to reduce adiposity. Ann Intern Med (2010) 2.30
Regulation of blood glucose by hypothalamic pyruvate metabolism. Science (2005) 2.28
Postnatal leptin surge and regulation of circadian rhythm of leptin by feeding. Implications for energy homeostasis and neuroendocrine function. J Clin Invest (1998) 2.23
Altered sleep regulation in leptin-deficient mice. Am J Physiol Regul Integr Comp Physiol (2005) 2.22
Nocturnal rise of leptin in lean, obese, and non-insulin-dependent diabetes mellitus subjects. J Clin Invest (1996) 2.20
Differential rescue of light- and food-entrainable circadian rhythms. Science (2008) 2.20
The DBP gene is expressed according to a circadian rhythm in the suprachiasmatic nucleus and influences circadian behavior. EMBO J (1997) 2.17
The circadian clock mutation alters sleep homeostasis in the mouse. J Neurosci (2000) 2.17
Circadian eating and sleeping patterns in the night eating syndrome. Obes Res (2004) 2.15
A daily rhythm in glucose tolerance: a role for the suprachiasmatic nucleus. Diabetes (2001) 2.07
The suprachiasmatic nucleus: a 25-year retrospective. J Biol Rhythms (1998) 2.03
The circadian rhythm of glucocorticoids is regulated by a gating mechanism residing in the adrenal cortical clock. Cell Metab (2006) 2.00
Regulation of monoamine oxidase A by circadian-clock components implies clock influence on mood. Curr Biol (2008) 1.97
Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats. J Clin Invest (2006) 1.94
SCN outputs and the hypothalamic balance of life. J Biol Rhythms (2006) 1.91
Reciprocal regulation of brain and muscle Arnt-like protein 1 and peroxisome proliferator-activated receptor alpha defines a novel positive feedback loop in the rodent liver circadian clock. Mol Endocrinol (2006) 1.91
Enhanced orexin receptor-2 signaling prevents diet-induced obesity and improves leptin sensitivity. Cell Metab (2009) 1.88
Association between polymorphisms in the Clock gene, obesity and the metabolic syndrome in man. Int J Obes (Lond) (2007) 1.88
Evidence for a circadian rhythm of insulin secretion. Am J Physiol (1996) 1.86
Aryl hydrocarbon receptor nuclear translocator-like (BMAL1) is associated with susceptibility to hypertension and type 2 diabetes. Proc Natl Acad Sci U S A (2007) 1.84
Glucocorticoid regulation of the circadian clock modulates glucose homeostasis. Proc Natl Acad Sci U S A (2009) 1.80
Increased body-mass index in patients with narcolepsy. Lancet (2000) 1.78
Obesity and metabolic syndrome in circadian Clock mutant mice. Science (2005) 12.66
Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes. Nature (2010) 5.97
The meter of metabolism. Cell (2008) 5.71
Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis. Science (2009) 5.30
High-fat diet disrupts behavioral and molecular circadian rhythms in mice. Cell Metab (2007) 4.93
Circadian timing of food intake contributes to weight gain. Obesity (Silver Spring) (2009) 3.44
Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice. Science (2013) 2.49
Circadian rhythms and metabolic syndrome: from experimental genetics to human disease. Circ Res (2010) 2.49
Gene set enrichment in eQTL data identifies novel annotations and pathway regulators. PLoS Genet (2008) 2.32
Altered sleep regulation in leptin-deficient mice. Am J Physiol Regul Integr Comp Physiol (2005) 2.22
Sleep and circadian rhythms: key components in the regulation of energy metabolism. FEBS Lett (2007) 2.03
Genomewide association analysis in diverse inbred mice: power and population structure. Genetics (2007) 2.01
A sense of time: how molecular clocks organize metabolism. Trends Endocrinol Metab (2006) 1.99
A divergent INS protein in Caenorhabditis elegans structurally resembles human insulin and activates the human insulin receptor. Genes Dev (2003) 1.46
The clockwork of metabolism. Annu Rev Nutr (2007) 1.45
Leptin deficiency and beta-cell dysfunction underlie type 2 diabetes in compound Akt knockout mice. Mol Cell Biol (2009) 1.19
Klf15 orchestrates circadian nitrogen homeostasis. Cell Metab (2012) 1.14
Clock genes and metabolic disease. J Appl Physiol (1985) (2009) 1.13
Circadian disruption and metabolic disease: findings from animal models. Best Pract Res Clin Endocrinol Metab (2010) 1.07
Circadian clocks and metabolism. Handb Exp Pharmacol (2013) 1.07
ROS-mediated PARP activity undermines mitochondrial function after permeability transition pore opening during myocardial ischemia-reperfusion. J Am Heart Assoc (2013) 1.06
Calreticulin and Hsp90 stabilize the human insulin receptor and promote its mobility in the endoplasmic reticulum. Proc Natl Acad Sci U S A (2007) 1.01
Usf1, a suppressor of the circadian Clock mutant, reveals the nature of the DNA-binding of the CLOCK:BMAL1 complex in mice. Elife (2013) 0.98
Nutrient sensing and the circadian clock. Trends Endocrinol Metab (2012) 0.98
Sleepless in America: a pathway to obesity and the metabolic syndrome? Arch Intern Med (2005) 0.96
Gamma-protocadherins regulate the functional integrity of hypothalamic feeding circuitry in mice. Dev Biol (2009) 0.93
Circadian rhythms: Redox redux. Nature (2011) 0.91
Mutational analysis of allosteric activation and inhibition of glucokinase. Biochem J (2011) 0.87
Repair of diverse diabetic defects of β-cells in man and mouse by pharmacological glucokinase activation. Diabetes Obes Metab (2012) 0.85
Generation of N-ethyl-N-nitrosourea (ENU) diabetes models in mice demonstrates genotype-specific action of glucokinase activators. J Biol Chem (2011) 0.84
Familial juvenile autoimmune hypothyroidism, pituitary enlargement, obesity, and insulin resistance. Thyroid (2004) 0.80
Obeying the clock yields benefits for metabolism. Proc Natl Acad Sci U S A (2009) 0.79
Physiology: On time metabolism. Nature (2011) 0.78
Circadian genes and insulin exocytosis. Cell Logist (2011) 0.78
Drug discovery: Time in a bottle. Nature (2012) 0.78
Circadian measurements of sirtuin biology. Methods Mol Biol (2013) 0.77
High glucose, no cry. Nat Med (2010) 0.77
Ghrelin-immunopositive hypothalamic neurons tie the circadian clock and visual system to the lateral hypothalamic arousal center. Mol Metab (2012) 0.77
Lean gene and the clock machine. Proc Natl Acad Sci U S A (2007) 0.77
Genetic advances in ophthalmology: the role of melanopsin-expressing, intrinsically photosensitive retinal ganglion cells in the circadian organization of the visual system. Semin Ophthalmol (2013) 0.75