Published in Proc Natl Acad Sci U S A on September 16, 2013
A deletion polymorphism in the Caenorhabditis elegans RIG-I homolog disables viral RNA dicing and antiviral immunity. Elife (2013) 1.08
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A heritable antiviral RNAi response limits Orsay virus infection in Caenorhabditis elegans N2. PLoS One (2014) 0.88
Engineering recombinant Orsay virus directly in the metazoan host Caenorhabditis elegans. J Virol (2014) 0.84
Dicer's role as an antiviral: still an enigma. Curr Opin Immunol (2013) 0.82
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Sensing viral RNAs by Dicer/RIG-I like ATPases across species. Curr Opin Immunol (2015) 0.79
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Distinct populations of primary and secondary effectors during RNAi in C. elegans. Science (2006) 7.15
Analysis of the C. elegans Argonaute family reveals that distinct Argonautes act sequentially during RNAi. Cell (2006) 7.14
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Nonself RNA-sensing mechanism of RIG-I helicase and activation of antiviral immune responses. Mol Cell (2008) 5.20
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Structural insights into RNA recognition by RIG-I. Cell (2011) 3.25
The Argonaute CSR-1 and its 22G-RNA cofactors are required for holocentric chromosome segregation. Cell (2009) 3.14
Structural basis of RNA recognition and activation by innate immune receptor RIG-I. Nature (2011) 3.05
RNA interference is an antiviral defence mechanism in Caenorhabditis elegans. Nature (2005) 2.93
LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses. Proc Natl Acad Sci U S A (2010) 2.90
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Structural basis for dsRNA recognition, filament formation, and antiviral signal activation by MDA5. Cell (2012) 2.34
The structural basis of 5' triphosphate double-stranded RNA recognition by RIG-I C-terminal domain. Structure (2010) 2.29
The DExD/H-box helicase Dicer-2 mediates the induction of antiviral activity in drosophila. Nat Immunol (2008) 2.18
An antiviral role for the RNA interference machinery in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2005) 2.16
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Is RNA interference involved in intrinsic antiviral immunity in mammals? Nat Immunol (2006) 2.02
Transgenerational inheritance of an acquired small RNA-based antiviral response in C. elegans. Cell (2011) 1.96
The 21-nucleotide, but not 22-nucleotide, viral secondary small interfering RNAs direct potent antiviral defense by two cooperative argonautes in Arabidopsis thaliana. Plant Cell (2011) 1.95
The regulatory domain of the RIG-I family ATPase LGP2 senses double-stranded RNA. Nucleic Acids Res (2009) 1.72
An RIG-I-Like RNA helicase mediates antiviral RNAi downstream of viral siRNA biogenesis in Caenorhabditis elegans. PLoS Pathog (2009) 1.49
RDE-1 slicer activity is required only for passenger-strand cleavage during RNAi in Caenorhabditis elegans. Nat Struct Mol Biol (2009) 1.35
Virus-derived siRNAs and piRNAs in immunity and pathogenesis. Curr Opin Virol (2011) 1.06
Convergent evolution of argonaute-2 slicer antagonism in two distinct insect RNA viruses. PLoS Pathog (2012) 1.04
Structural insights into the activation of RIG-I, a nanosensor for viral RNAs. EMBO Rep (2011) 0.97
Silencing of host genes directed by virus-derived short interfering RNAs in Caenorhabditis elegans. J Virol (2012) 0.95
Characterization of virus-encoded RNA interference suppressors in Caenorhabditis elegans. J Virol (2013) 0.90
Recognition of viruses in the cytoplasm by RLRs and other helicases--how conformational changes, mitochondrial dynamics and ubiquitination control innate immune responses. Int Immunol (2012) 0.82
Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure. Cell (2013) 6.47
Extreme learning machine for regression and multiclass classification. IEEE Trans Syst Man Cybern B Cybern (2011) 5.93
RNA interference directs innate immunity against viruses in adult Drosophila. Science (2006) 5.74
Virus discovery by deep sequencing and assembly of virus-derived small silencing RNAs. Proc Natl Acad Sci U S A (2010) 3.92
Interferon antagonist proteins of influenza and vaccinia viruses are suppressors of RNA silencing. Proc Natl Acad Sci U S A (2004) 3.85
Benign prostatic hyperplasia: prostatic arterial embolization versus transurethral resection of the prostate--a prospective, randomized, and controlled clinical trial. Radiology (2013) 3.32
The prevalence of regulatory T cells in lymphoid tissue is correlated with viral load in HIV-infected patients. J Immunol (2005) 3.21
Virus counterdefense: diverse strategies for evading the RNA-silencing immunity. Annu Rev Microbiol (2006) 3.15
HIV-1-driven regulatory T-cell accumulation in lymphoid tissues is associated with disease progression in HIV/AIDS. Blood (2006) 2.95
RNA interference functions as an antiviral immunity mechanism in mammals. Science (2013) 2.77
Ubiquitin ligase-associated protein SGT1 is required for host and nonhost disease resistance in plants. Proc Natl Acad Sci U S A (2002) 2.76
Large-scale in silico and microarray-based identification of direct 1,25-dihydroxyvitamin D3 target genes. Mol Endocrinol (2005) 2.73
Six RNA viruses and forty-one hosts: viral small RNAs and modulation of small RNA repertoires in vertebrate and invertebrate systems. PLoS Pathog (2010) 2.62
Quantitative proteome analysis of human plasma following in vivo lipopolysaccharide administration using 16O/18O labeling and the accurate mass and time tag approach. Mol Cell Proteomics (2005) 2.50
Mechanism of induction and suppression of antiviral immunity directed by virus-derived small RNAs in Drosophila. Cell Host Microbe (2008) 2.48
Suppression of antiviral silencing by cucumber mosaic virus 2b protein in Arabidopsis is associated with drastically reduced accumulation of three classes of viral small interfering RNAs. Plant Cell (2007) 2.43
In vitro and in vivo targeting of hollow gold nanoshells directed at epidermal growth factor receptor for photothermal ablation therapy. Mol Cancer Ther (2008) 2.34
Worldwide survey on the use of navigation in spine surgery. World Neurosurg (2012) 2.23
Targeted photothermal ablation of murine melanomas with melanocyte-stimulating hormone analog-conjugated hollow gold nanospheres. Clin Cancer Res (2009) 2.22
RNAi-mediated viral immunity requires amplification of virus-derived siRNAs in Arabidopsis thaliana. Proc Natl Acad Sci U S A (2009) 2.19
Excerpts from the United States Renal Data System 2006 Annual Data Report. Am J Kidney Dis (2007) 2.16
Influence of anchoring ligands and particle size on the colloidal stability and in vivo biodistribution of polyethylene glycol-coated gold nanoparticles in tumor-xenografted mice. Biomaterials (2009) 2.13
Characterization of piezoelectric materials with large piezoelectric and electromechanical coupling coefficients. Ultrasonics (2003) 2.12
The phosphodiesterase-5 inhibitor vardenafil reduces oxidative stress while reversing pulmonary arterial hypertension. Cardiovasc Res (2013) 2.08
c-Myc-mediated epigenetic silencing of MicroRNA-101 contributes to dysregulation of multiple pathways in hepatocellular carcinoma. Hepatology (2014) 2.04
A chelator-free multifunctional [64Cu]CuS nanoparticle platform for simultaneous micro-PET/CT imaging and photothermal ablation therapy. J Am Chem Soc (2010) 2.02
Excerpts from the United States Renal Data System 2007 annual data report. Am J Kidney Dis (2008) 2.01
Identifying RNA editing sites using RNA sequencing data alone. Nat Methods (2013) 2.00
The 21-nucleotide, but not 22-nucleotide, viral secondary small interfering RNAs direct potent antiviral defense by two cooperative argonautes in Arabidopsis thaliana. Plant Cell (2011) 1.95
Automated 20 kpsi RPLC-MS and MS/MS with chromatographic peak capacities of 1000-1500 and capabilities in proteomics and metabolomics. Anal Chem (2005) 1.87
Reprogrammed mouse fibroblasts differentiate into cells of the cardiovascular and hematopoietic lineages. Stem Cells (2008) 1.83
Piezoelectric properties of domain engineered barium titanate single crystals with different volume fractions of domain walls. J Appl Phys (2009) 1.82
Skewer: a fast and accurate adapter trimmer for next-generation sequencing paired-end reads. BMC Bioinformatics (2014) 1.82
RNA-based viral immunity initiated by the Dicer family of host immune receptors. Immunol Rev (2009) 1.82
A-to-I RNA editing occurs at over a hundred million genomic sites, located in a majority of human genes. Genome Res (2013) 1.81
Spontaneously beating cardiomyocytes derived from white mature adipocytes. Cardiovasc Res (2010) 1.76
Transparent triboelectric nanogenerators and self-powered pressure sensors based on micropatterned plastic films. Nano Lett (2012) 1.69
Three distinct suppressors of RNA silencing encoded by a 20-kb viral RNA genome. Proc Natl Acad Sci U S A (2004) 1.67
A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus. Nat Genet (2013) 1.67
Receptor-mediated transcytosis: a mechanism for active extravascular transport of nanoparticles in solid tumors. J Control Release (2012) 1.61
Tumor site-specific silencing of NF-kappaB p65 by targeted hollow gold nanosphere-mediated photothermal transfection. Cancer Res (2010) 1.60
Survivin: a novel player in insulin cardioprotection against myocardial ischemia/reperfusion injury. J Mol Cell Cardiol (2010) 1.58
Design and structure-activity relationships of potent and selective inhibitors of undecaprenyl pyrophosphate synthase (UPPS): tetramic, tetronic acids and dihydropyridin-2-ones. Bioorg Med Chem Lett (2008) 1.57
RNA silencing: a conserved antiviral immunity of plants and animals. Virus Res (2004) 1.54
Role of splanchnic hemodynamics in liver regeneration after living donor liver transplantation. Liver Transpl (2009) 1.53
Myricetin protects cells against oxidative stress-induced apoptosis via regulation of PI3K/Akt and MAPK signaling pathways. Int J Mol Sci (2010) 1.53
Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus. Nat Genet (2012) 1.52
An RIG-I-Like RNA helicase mediates antiviral RNAi downstream of viral siRNA biogenesis in Caenorhabditis elegans. PLoS Pathog (2009) 1.49
Small molecule Me6TREN mobilizes hematopoietic stem/progenitor cells by activating MMP-9 expression and disrupting SDF-1/CXCR4 axis. Blood (2013) 1.49
Mutations in TUBB8 and Human Oocyte Meiotic Arrest. N Engl J Med (2016) 1.46
Effects of photoacoustic imaging and photothermal ablation therapy mediated by targeted hollow gold nanospheres in an orthotopic mouse xenograft model of glioma. Cancer Res (2011) 1.45
Automated gain control and internal calibration with external ion accumulation capillary liquid chromatography-electrospray ionization Fourier transform ion cyclotron resonance. Anal Chem (2003) 1.45
Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 16: bone graft extenders and substitutes. J Neurosurg Spine (2005) 1.43
A nonpeptidic agonist of glucagon-like peptide 1 receptors with efficacy in diabetic db/db mice. Proc Natl Acad Sci U S A (2007) 1.43
An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting. Mol Cell (2012) 1.43
Feasibility of using wire-guided needle-knife electrocautery for refractory biliary and pancreatic strictures. Gastrointest Endosc (2013) 1.41
Direct and indirect roles of viral suppressors of RNA silencing in pathogenesis. Annu Rev Phytopathol (2008) 1.40
Linear IgA disease limited to the oral mucosa. J Am Acad Dermatol (2011) 1.40
MicroRNA-320a suppresses human colon cancer cell proliferation by directly targeting β-catenin. Biochem Biophys Res Commun (2012) 1.40
Viral suppressors of RNA-based viral immunity: host targets. Cell Host Microbe (2010) 1.38
Cytochrome p450 compound I. J Am Chem Soc (2006) 1.37
Antiviral silencing in animals. FEBS Lett (2005) 1.36
NRG1, a CC-NB-LRR protein, together with N, a TIR-NB-LRR protein, mediates resistance against tobacco mosaic virus. Curr Biol (2005) 1.36
Treating type 2 diabetes mellitus with traditional chinese and Indian medicinal herbs. Evid Based Complement Alternat Med (2013) 1.34
Genomes of the rice pest brown planthopper and its endosymbionts reveal complex complementary contributions for host adaptation. Genome Biol (2014) 1.34
Kinetic studies of reactions of iron(IV)-oxo porphyrin radical cations with organic reductants. J Inorg Biochem (2006) 1.32
High performance of graphene oxide-doped silicon oxide-based resistance random access memory. Nanoscale Res Lett (2013) 1.31
Luman/CREB3 induces transcription of the endoplasmic reticulum (ER) stress response protein Herp through an ER stress response element. Mol Cell Biol (2006) 1.29
Mechanism of and requirement for estrogen-regulated MYB expression in estrogen-receptor-positive breast cancer cells. Proc Natl Acad Sci U S A (2007) 1.27
Anopheles gambiae cadherin AgCad1 binds the Cry4Ba toxin of Bacillus thuringiensis israelensis and a fragment of AgCad1 synergizes toxicity. Biochemistry (2008) 1.25
MeRNA: a database of metal ion binding sites in RNA structures. Nucleic Acids Res (2006) 1.24
Effective photothermal chemotherapy using doxorubicin-loaded gold nanospheres that target EphB4 receptors in tumors. Cancer Res (2012) 1.24
Photochemical production of a highly reactive porphyrin-iron-oxo species. Inorg Chem (2007) 1.23
MicroRNA-203 leads to G1 phase cell cycle arrest in laryngeal carcinoma cells by directly targeting survivin. FEBS Lett (2012) 1.22
HER2 interacts with CD44 to up-regulate CXCR4 via epigenetic silencing of microRNA-139 in gastric cancer cells. Gastroenterology (2011) 1.22
Notch signaling pathway and cancer metastasis. Adv Exp Med Biol (2012) 1.21
Photochemical generation of a highly reactive iron-oxo intermediate. A true iron(V)-oxo species? J Am Chem Soc (2005) 1.21
Blockage of JAK/STAT signalling attenuates renal ischaemia-reperfusion injury in rat. Nephrol Dial Transplant (2007) 1.20
Suppression of Arabidopsis ARGONAUTE1-mediated slicing, transgene-induced RNA silencing, and DNA methylation by distinct domains of the Cucumber mosaic virus 2b protein. Plant Cell (2012) 1.19
MicroRNA-125b induces metastasis by targeting STARD13 in MCF-7 and MDA-MB-231 breast cancer cells. PLoS One (2012) 1.19
Generation of insulin-producing cells from PDX-1 gene-modified human mesenchymal stem cells. J Cell Physiol (2007) 1.18
Independent control of ion transmission in a jet disrupter dual-channel ion funnel electrospray ionization MS interface. Anal Chem (2002) 1.18
Role of interferon regulatory factor 4 in the regulation of pathological cardiac hypertrophy. Hypertension (2013) 1.15
Label-free, electrical detection of the SARS virus N-protein with nanowire biosensors utilizing antibody mimics as capture probes. ACS Nano (2009) 1.14
Luman is capable of binding and activating transcription from the unfolded protein response element. Biochem Biophys Res Commun (2005) 1.14
Proteomic analysis of proteins involved in spermiogenesis in mouse. J Proteome Res (2010) 1.13
Genome sequence and global sequence variation map with 5.5 million SNPs in Chinese rhesus macaque. Genome Biol (2011) 1.13
Pulse pressure and mean arterial pressure in relation to ischemic stroke among patients with uncontrolled hypertension in rural areas of China. Stroke (2008) 1.13
siRNAs compete with miRNAs for methylation by HEN1 in Arabidopsis. Nucleic Acids Res (2010) 1.12
Stk40 links the pluripotency factor Oct4 to the Erk/MAPK pathway and controls extraembryonic endoderm differentiation. Proc Natl Acad Sci U S A (2010) 1.12
Homology-independent discovery of replicating pathogenic circular RNAs by deep sequencing and a new computational algorithm. Proc Natl Acad Sci U S A (2012) 1.12
Space electric field concentrated effect for Zr:SiO2 RRAM devices using porous SiO2 buffer layer. Nanoscale Res Lett (2013) 1.11
Armored long RNA controls or standards for branched DNA assay for detection of human immunodeficiency virus type 1. J Clin Microbiol (2009) 1.09
NDRG2 inhibits hepatocellular carcinoma adhesion, migration and invasion by regulating CD24 expression. BMC Cancer (2011) 1.09
Molecular basis of traditional Chinese medicine in cancer chemoprevention. Curr Drug Discov Technol (2010) 1.08
Salt-sensitive splice variant of nNOS expressed in the macula densa cells. Am J Physiol Renal Physiol (2010) 1.08