Published in RNA on September 23, 2013
CYFIP family proteins between autism and intellectual disability: links with Fragile X syndrome. Front Cell Neurosci (2014) 0.89
Premutation in the Fragile X Mental Retardation 1 (FMR1) Gene Affects Maternal Zn-milk and Perinatal Brain Bioenergetics and Scaffolding. Front Neurosci (2016) 0.79
Altered redox mitochondrial biology in the neurodegenerative disorder fragile X-tremor/ataxia syndrome: use of antioxidants in precision medicine. Mol Med (2016) 0.75
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods (2001) 414.27
FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism. Cell (2011) 8.46
Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome. Cell (2001) 8.04
Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function. Cell (2001) 6.50
Dendritic spine pathology in neuropsychiatric disorders. Nat Neurosci (2011) 4.80
Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits. Proc Natl Acad Sci U S A (1997) 4.73
p120-catenin and p190RhoGAP regulate cell-cell adhesion by coordinating antagonism between Rac and Rho. Cell (2006) 4.24
Elongation factor 2 and fragile X mental retardation protein control the dynamic translation of Arc/Arg3.1 essential for mGluR-LTD. Neuron (2008) 3.97
Actin in action: the interplay between the actin cytoskeleton and synaptic efficacy. Nat Rev Neurosci (2008) 3.83
Abnormal dendritic spine characteristics in the temporal and visual cortices of patients with fragile-X syndrome: a quantitative examination. Am J Med Genet (2001) 3.77
Structural dynamics of dendritic spines in memory and cognition. Trends Neurosci (2010) 3.65
p120 catenin regulates the actin cytoskeleton via Rho family GTPases. J Cell Biol (2000) 3.60
RNA cargoes associating with FMRP reveal deficits in cellular functioning in Fmr1 null mice. Neuron (2003) 3.58
Dendritic spine structural anomalies in fragile-X mental retardation syndrome. Cereb Cortex (2000) 3.43
The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif. EMBO J (2001) 3.42
Actin-based plasticity in dendritic spines. Science (2000) 3.24
Gene function correlates with potential for G4 DNA formation in the human genome. Nucleic Acids Res (2006) 3.13
FMRP targets distinct mRNA sequence elements to regulate protein expression. Nature (2012) 2.95
Phosphorylation influences the translation state of FMRP-associated polyribosomes. Hum Mol Genet (2003) 2.66
QGRS Mapper: a web-based server for predicting G-quadruplexes in nucleotide sequences. Nucleic Acids Res (2006) 2.62
Molecular mechanisms of dendritic spine development and remodeling. Prog Neurobiol (2005) 2.54
A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability. Nat Neurosci (2007) 2.54
A direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome. Dev Cell (2008) 2.51
p120 catenin affects cell motility via modulation of activity of Rho-family GTPases: a link between cell-cell contact formation and regulation of cell locomotion. J Cell Sci (2001) 2.40
Molecular mechanisms of fragile X syndrome: a twenty-year perspective. Annu Rev Pathol (2011) 2.39
Kissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes. Genes Dev (2005) 2.38
Regulation of Rho GTPases by p120-catenin. Curr Opin Cell Biol (2001) 2.34
Reversible inhibition of PSD-95 mRNA translation by miR-125a, FMRP phosphorylation, and mGluR signaling. Mol Cell (2011) 2.27
Mammalian Abp1, a signal-responsive F-actin-binding protein, links the actin cytoskeleton to endocytosis via the GTPase dynamin. J Cell Biol (2001) 2.26
Rho GTPases, dendritic structure, and mental retardation. J Neurobiol (2005) 2.19
A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P. Proc Natl Acad Sci U S A (2001) 2.17
Emerging roles for p120-catenin in cell adhesion and cancer. Oncogene (2004) 2.12
p120 catenin regulates dendritic spine and synapse development through Rho-family GTPases and cadherins. Neuron (2006) 2.10
The state of synapses in fragile X syndrome. Neuroscientist (2009) 2.07
FMRP phosphorylation reveals an immediate-early signaling pathway triggered by group I mGluR and mediated by PP2A. J Neurosci (2007) 2.02
Genome-wide screen reveals APC-associated RNAs enriched in cell protrusions. Nature (2008) 1.98
Control of dendritic development by the Drosophila fragile X-related gene involves the small GTPase Rac1. Development (2003) 1.91
Inhibition of p21-activated kinase rescues symptoms of fragile X syndrome in mice. Proc Natl Acad Sci U S A (2007) 1.91
S6K1 phosphorylates and regulates fragile X mental retardation protein (FMRP) with the neuronal protein synthesis-dependent mammalian target of rapamycin (mTOR) signaling cascade. J Biol Chem (2008) 1.87
Deletion of the neuron-specific protein delta-catenin leads to severe cognitive and synaptic dysfunction. Curr Biol (2004) 1.80
Delayed stabilization of dendritic spines in fragile X mice. J Neurosci (2010) 1.69
The fragile X mental retardation protein binds and regulates a novel class of mRNAs containing U rich target sequences. Neuroscience (2003) 1.69
Structural plasticity of dendritic spines. Curr Opin Neurobiol (2011) 1.68
FMRP interferes with the Rac1 pathway and controls actin cytoskeleton dynamics in murine fibroblasts. Hum Mol Genet (2005) 1.60
Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs. Hum Mol Genet (2009) 1.53
Hemizygosity of delta-catenin (CTNND2) is associated with severe mental retardation in cri-du-chat syndrome. Genomics (2000) 1.47
The p120 family of cell adhesion molecules. Eur J Cell Biol (2005) 1.41
A novel function for fragile X mental retardation protein in translational activation. PLoS Biol (2009) 1.38
Fragile X mental retardation protein regulates protein expression and mRNA translation of the potassium channel Kv4.2. J Neurosci (2011) 1.30
Species-dependent posttranscriptional regulation of NOS1 by FMRP in the developing cerebral cortex. Cell (2012) 1.28
Fragile X Mental Retardation protein determinants required for its association with polyribosomal mRNPs. Hum Mol Genet (2003) 1.27
Delta-catenin regulates spine and synapse morphogenesis and function in hippocampal neurons during development. J Neurosci (2009) 1.24
Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome. Nat Commun (2012) 1.24
Physiological activation of synaptic Rac>PAK (p-21 activated kinase) signaling is defective in a mouse model of fragile X syndrome. J Neurosci (2010) 1.22
Evidence for a fragile X mental retardation protein-mediated translational switch in metabotropic glutamate receptor-triggered Arc translation and long-term depression. J Neurosci (2012) 1.21
A metabolomic and systems biology perspective on the brain of the fragile X syndrome mouse model. Genome Res (2011) 1.16
The armadillo protein p0071 regulates Rho signalling during cytokinesis. Nat Cell Biol (2006) 1.16
X-linked mental retardation: focus on synaptic function and plasticity. J Neurochem (2009) 1.08
The dynamic cytoskeleton: backbone of dendritic spine plasticity. Curr Opin Neurobiol (2010) 1.07
Casein kinase II phosphorylates the fragile X mental retardation protein and modulates its biological properties. Mol Cell Biol (2002) 1.06
The functions of the actin nucleator Cobl in cellular morphogenesis critically depend on syndapin I. EMBO J (2011) 0.98
The actin nucleator Cobl is crucial for Purkinje cell development and works in close conjunction with the F-actin binding protein Abp1. J Neurosci (2012) 0.96
Emerging major synaptic signaling pathways involved in intellectual disability. Mol Psychiatry (2011) 0.94
Modulation of dendritic spines and synaptic function by Rac1: a possible link to Fragile X syndrome pathology. Brain Res (2011) 0.92
CyloFold: secondary structure prediction including pseudoknots. Nucleic Acids Res (2010) 0.90
Identification of FMRP-associated mRNAs using yeast three-hybrid system. Am J Med Genet B Neuropsychiatr Genet (2008) 0.83
A Boyden chamber-based method for characterization of astrocyte protrusion localized RNA and protein. Glia (2011) 0.81
Spatial regulation of beta-actin translation by Src-dependent phosphorylation of ZBP1. Nature (2005) 5.29
Single cell behavior in metastatic primary mammary tumors correlated with gene expression patterns revealed by molecular profiling. Cancer Res (2002) 3.95
Cordon-bleu is an actin nucleation factor and controls neuronal morphology. Cell (2007) 2.79
Molecular dissection of the photoreceptor ribbon synapse: physical interaction of Bassoon and RIBEYE is essential for the assembly of the ribbon complex. J Cell Biol (2005) 2.48
Neural Wiskott Aldrich Syndrome Protein (N-WASP) and the Arp2/3 complex are recruited to sites of clathrin-mediated endocytosis in cultured fibroblasts. Eur J Cell Biol (2004) 2.28
Syndapins integrate N-WASP in receptor-mediated endocytosis. EMBO J (2002) 1.95
EHD proteins associate with syndapin I and II and such interactions play a crucial role in endosomal recycling. Mol Biol Cell (2005) 1.86
ZBP1 regulates mRNA stability during cellular stress. J Cell Biol (2006) 1.84
Protein binding and functional characterization of plakophilin 2. Evidence for its diverse roles in desmosomes and beta -catenin signaling. J Biol Chem (2002) 1.84
Endocytosis and the cytoskeleton. Int Rev Cytol (2002) 1.82
Temporal and spatial coordination of exocytosis and endocytosis. Nat Rev Mol Cell Biol (2003) 1.68
The PTB interacting protein raver1 regulates alpha-tropomyosin alternative splicing. EMBO J (2003) 1.68
Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): post-transcriptional drivers of cancer progression? Cell Mol Life Sci (2012) 1.68
Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs. RNA (2008) 1.63
A peptide motif in Raver1 mediates splicing repression by interaction with the PTB RRM2 domain. Nat Struct Mol Biol (2006) 1.52
The syndapin protein family: linking membrane trafficking with the cytoskeleton. J Cell Sci (2004) 1.50
A novel cell-cell junction system: the cortex adhaerens mosaic of lens fiber cells. J Cell Sci (2003) 1.46
Activation of oligodendroglial Fyn kinase enhances translation of mRNAs transported in hnRNP A2-dependent RNA granules. J Cell Biol (2008) 1.44
Linkage of the actin cytoskeleton to the postsynaptic density via direct interactions of Abp1 with the ProSAP/Shank family. J Neurosci (2004) 1.44
New players in actin polymerization--WH2-domain-containing actin nucleators. Trends Cell Biol (2009) 1.44
Syndapin oligomers interconnect the machineries for endocytic vesicle formation and actin polymerization. J Biol Chem (2006) 1.38
She2p is a novel RNA binding protein with a basic helical hairpin motif. Cell (2004) 1.37
Defining desmosomal plakophilin-3 interactions. J Cell Biol (2003) 1.36
ZBP2 facilitates binding of ZBP1 to beta-actin mRNA during transcription. Mol Cell Biol (2007) 1.35
Drosophila Cip4/Toca-1 integrates membrane trafficking and actin dynamics through WASP and SCAR/WAVE. Curr Biol (2009) 1.33
Golgi vesicle proteins are linked to the assembly of an actin complex defined by mAbp1. Mol Biol Cell (2002) 1.29
Regulation of N-WASP and the Arp2/3 complex by Abp1 controls neuronal morphology. PLoS One (2007) 1.26
The actin-binding protein Abp1 controls dendritic spine morphology and is important for spine head and synapse formation. J Neurosci (2008) 1.24
Promotion of importin alpha-mediated nuclear import by the phosphorylation-dependent binding of cargo protein to 14-3-3. J Cell Biol (2005) 1.23
Maturation of mammalian H/ACA box snoRNAs: PAPD5-dependent adenylation and PARN-dependent trimming. RNA (2012) 1.22
Interactions between Piccolo and the actin/dynamin-binding protein Abp1 link vesicle endocytosis to presynaptic active zones. J Biol Chem (2003) 1.22
F-BAR proteins of the syndapin family shape the plasma membrane and are crucial for neuromorphogenesis. J Neurosci (2009) 1.21
IGF2BP1 promotes cell migration by regulating MK5 and PTEN signaling. Genes Dev (2012) 1.20
LIM kinase 1 and cofilin regulate actin filament population required for dynamin-dependent apical carrier fission from the trans-Golgi network. Mol Biol Cell (2008) 1.18
The mitotic-spindle-associated protein astrin is essential for progression through mitosis. J Cell Sci (2002) 1.18
The armadillo protein p0071 regulates Rho signalling during cytokinesis. Nat Cell Biol (2006) 1.16
Keratins mediate localization of hemidesmosomes and repress cell motility. J Invest Dermatol (2012) 1.15
Complexes of syndapin II with dynamin II promote vesicle formation at the trans-Golgi network. J Cell Sci (2006) 1.13
Impairing actin filament or syndapin functions promotes accumulation of clathrin-coated vesicles at the apical plasma membrane of acinar epithelial cells. Mol Biol Cell (2003) 1.13
Proper synaptic vesicle formation and neuronal network activity critically rely on syndapin I. EMBO J (2011) 1.11
IGF2BP1 enhances HCV IRES-mediated translation initiation via the 3'UTR. RNA (2009) 1.10
Ezrin expression is related to poor prognosis in FIGO stage I endometrioid carcinomas. Mod Pathol (2006) 1.08
Actin-binding protein 1 regulates B cell receptor-mediated antigen processing and presentation in response to B cell receptor activation. J Immunol (2008) 1.05
The Armadillo family protein p0071 is a VE-cadherin- and desmoplakin-binding protein. J Biol Chem (2002) 1.05
Interaction between Erbin and a Catenin-related protein in epithelial cells. J Biol Chem (2001) 1.05
Plakophilin 1 stimulates translation by promoting eIF4A1 activity. J Cell Biol (2010) 1.04
A spastic paraplegia mouse model reveals REEP1-dependent ER shaping. J Clin Invest (2013) 1.03
Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) is an important protumorigenic factor in hepatocellular carcinoma. Hepatology (2014) 1.00
Alpha-synuclein aggregation involves a bafilomycin A 1-sensitive autophagy pathway. Autophagy (2012) 1.00
Pathogenic mechanisms of deregulated microRNA expression in thyroid carcinomas of follicular origin. Thyroid Res (2011) 0.99
The functions of the actin nucleator Cobl in cellular morphogenesis critically depend on syndapin I. EMBO J (2011) 0.98
Folliculin interacts with p0071 (plakophilin-4) and deficiency is associated with disordered RhoA signalling, epithelial polarization and cytokinesis. Hum Mol Genet (2012) 0.98
Controlling actin cytoskeletal organization and dynamics during neuronal morphogenesis. Eur J Cell Biol (2010) 0.97
The actin nucleator Cobl is crucial for Purkinje cell development and works in close conjunction with the F-actin binding protein Abp1. J Neurosci (2012) 0.96
Emerging functions: diseases and animal models reshape our view of the cytoskeleton. Exp Cell Res (2004) 0.93
Near-infrared (NIR) dye-labeled RNAs identify binding of ZBP1 to the noncoding Y3-RNA. RNA (2010) 0.91
Rapid identification of regulatory microRNAs by miTRAP (miRNA trapping by RNA in vitro affinity purification). Nucleic Acids Res (2014) 0.90
Beyond regulation of cell adhesion: local control of RhoA at the cleavage furrow by the p0071 catenin. Cell Cycle (2007) 0.89
Insulin signaling via Akt2 switches plakophilin 1 function from stabilizing cell adhesion to promoting cell proliferation. J Cell Sci (2013) 0.88
Ultrastructural freeze-fracture immunolabeling identifies plasma membrane-localized syndapin II as a crucial factor in shaping caveolae. Histochem Cell Biol (2012) 0.86
Ciliated sensory hair cell formation and function require the F-BAR protein syndapin I and the WH2 domain-based actin nucleator Cobl. J Cell Sci (2012) 0.86
IGF2BP1: a post-transcriptional "driver" of tumor cell migration. Cell Adh Migr (2012) 0.86
Subcellular localization and RNP formation of IGF2BPs (IGF2 mRNA-binding proteins) is modulated by distinct RNA-binding domains. Biol Chem (2013) 0.86
Abp1 utilizes the Arp2/3 complex activator Scar/WAVE in bristle development. J Cell Sci (2012) 0.86
Targeting of p0071 to the midbody depends on KIF3. J Cell Sci (2009) 0.84
ProSAP1 and membrane nanodomain-associated syndapin I promote postsynapse formation and function. J Cell Biol (2014) 0.84
p0071/PKP4, a multifunctional protein coordinating cell adhesion with cytoskeletal organization. Biol Chem (2013) 0.83
IGF2BP1 promotes mesenchymal cell properties and migration of tumor-derived cells by enhancing the expression of LEF1 and SNAI2 (SLUG). Nucleic Acids Res (2013) 0.82
Olfactory neuron-specific expression of A30P α-synuclein exacerbates dopamine deficiency and hyperactivity in a novel conditional model of early Parkinson's disease stages. Neurobiol Dis (2011) 0.81
From the nucleus toward the cell periphery: a guided tour for mRNAs. News Physiol Sci (2003) 0.80
Proteomic analysis of glycine receptor β subunit (GlyRβ)-interacting proteins: evidence for syndapin I regulating synaptic glycine receptors. J Biol Chem (2014) 0.80