Published in EMBO J on September 03, 2001
FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism. Cell (2011) 8.46
Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function. Neuron (2008) 6.26
A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins. Genes Dev (2002) 6.10
Elongation factor 2 and fragile X mental retardation protein control the dynamic translation of Arc/Arg3.1 essential for mGluR-LTD. Neuron (2008) 3.97
FMRP targets distinct mRNA sequence elements to regulate protein expression. Nature (2012) 2.95
The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95. Proc Natl Acad Sci U S A (2003) 2.82
FMRP mediates mGluR5-dependent translation of amyloid precursor protein. PLoS Biol (2007) 2.75
A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability. Nat Neurosci (2007) 2.54
Kissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes. Genes Dev (2005) 2.38
5'-UTR RNA G-quadruplexes: translation regulation and targeting. Nucleic Acids Res (2012) 2.36
Reduced FMR1 mRNA translation efficiency in fragile X patients with premutations. RNA (2002) 2.06
The effect of chemical modifications on the thermal stability of different G-quadruplex-forming oligonucleotides. Nucleic Acids Res (2005) 2.04
Dicer-derived microRNAs are utilized by the fragile X mental retardation protein for assembly on target RNAs. J Biomed Biotechnol (2006) 2.02
Visualization of RNA-protein interactions in living cells: FMRP and IMP1 interact on mRNAs. EMBO J (2004) 1.99
Transport of Drosophila fragile X mental retardation protein-containing ribonucleoprotein granules by kinesin-1 and cytoplasmic dynein. Proc Natl Acad Sci U S A (2004) 1.99
Fragile X mental retardation protein is necessary for neurotransmitter-activated protein translation at synapses. Proc Natl Acad Sci U S A (2004) 1.97
Biochemical evidence for the association of fragile X mental retardation protein with brain polyribosomal ribonucleoparticles. Proc Natl Acad Sci U S A (2004) 1.96
Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cells. Nucleic Acids Res (2009) 1.93
Natural and pharmacological regulation of telomerase. Nucleic Acids Res (2002) 1.92
Fragile X protein FMRP is required for homeostatic plasticity and regulation of synaptic strength by retinoic acid. J Neurosci (2010) 1.92
Fragile X mental retardation protein regulates translation by binding directly to the ribosome. Mol Cell (2014) 1.83
FMR1: a gene with three faces. Biochim Biophys Acta (2009) 1.77
Signatures of RNA binding proteins globally coupled to effective microRNA target sites. Genome Res (2010) 1.75
The fragile X mental retardation protein and group I metabotropic glutamate receptors regulate levels of mRNA granules in brain. Proc Natl Acad Sci U S A (2005) 1.74
A single internal ribosome entry site containing a G quartet RNA structure drives fibroblast growth factor 2 gene expression at four alternative translation initiation codons. J Biol Chem (2003) 1.67
On BC1 RNA and the fragile X mental retardation protein. Proc Natl Acad Sci U S A (2008) 1.56
G-quartet-dependent recognition between the FMRP RGG box and RNA. RNA (2003) 1.54
RNA binding protein sex-lethal (Sxl) and control of Drosophila sex determination and dosage compensation. Microbiol Mol Biol Rev (2003) 1.53
Drosophila fragile X mental retardation protein developmentally regulates activity-dependent axon pruning. Development (2008) 1.52
Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells. Nat Chem (2013) 1.48
G-quadruplex RNA structure as a signal for neurite mRNA targeting. EMBO Rep (2011) 1.46
Fragile X mental retardation protein is required for synapse elimination by the activity-dependent transcription factor MEF2. Neuron (2010) 1.46
Neuronal ELAV proteins enhance mRNA stability by a PKCalpha-dependent pathway. Proc Natl Acad Sci U S A (2005) 1.45
Dendritic BC1 RNA in translational control mechanisms. J Cell Biol (2005) 1.45
Transport of fragile X mental retardation protein via granules in neurites of PC12 cells. Mol Cell Biol (2002) 1.42
RNA-Binding Protein FXR1 Regulates p21 and TERC RNA to Bypass p53-Mediated Cellular Senescence in OSCC. PLoS Genet (2016) 1.42
The fragile X mental retardation protein has nucleic acid chaperone properties. Nucleic Acids Res (2004) 1.42
Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction. Nat Struct Mol Biol (2011) 1.38
A novel function for fragile X mental retardation protein in translational activation. PLoS Biol (2009) 1.38
The FMR1 gene and fragile X-associated tremor/ataxia syndrome. Am J Med Genet B Neuropsychiatr Genet (2009) 1.37
A mouse model of the human Fragile X syndrome I304N mutation. PLoS Genet (2009) 1.36
The G-quartet containing FMRP binding site in FMR1 mRNA is a potent exonic splicing enhancer. Nucleic Acids Res (2008) 1.32
Histone H2a mRNA interacts with Lin28 and contains a Lin28-dependent posttranscriptional regulatory element. Nucleic Acids Res (2009) 1.31
Species-dependent posttranscriptional regulation of NOS1 by FMRP in the developing cerebral cortex. Cell (2012) 1.28
Elevated glycogen synthase kinase-3 activity in Fragile X mice: key metabolic regulator with evidence for treatment potential. Neuropharmacology (2008) 1.28
Small-molecule-mediated G-quadruplex isolation from human cells. Nat Chem (2010) 1.26
Altered mRNA transport, docking, and protein translation in neurons lacking fragile X mental retardation protein. Proc Natl Acad Sci U S A (2010) 1.25
Fragile X related protein 1 isoforms differentially modulate the affinity of fragile X mental retardation protein for G-quartet RNA structure. Nucleic Acids Res (2006) 1.19
Cells lacking the fragile X mental retardation protein (FMRP) have normal RISC activity but exhibit altered stress granule assembly. Mol Biol Cell (2008) 1.17
Mechanistic relationships between Drosophila fragile X mental retardation protein and metabotropic glutamate receptor A signaling. Mol Cell Neurosci (2008) 1.15
A G-quadruplex structure within the 5'-UTR of TRF2 mRNA represses translation in human cells. Nucleic Acids Res (2010) 1.13
Fragile X mental retardation protein FMRP binds mRNAs in the nucleus. Mol Cell Biol (2008) 1.11
Defects in translational regulation contributing to human cognitive and behavioral disease. Curr Opin Genet Dev (2011) 1.09
Interactions of the G quartet forming semaphorin 3F RNA with the RGG box domain of the fragile X protein family. Nucleic Acids Res (2007) 1.08
Arginines of the RGG box regulate FMRP association with polyribosomes and mRNA. Hum Mol Genet (2010) 1.08
Fragile X mental retardation protein interactions with the microtubule associated protein 1B RNA. RNA (2008) 1.07
The C-terminus of nucleolin promotes the formation of the c-MYC G-quadruplex and inhibits c-MYC promoter activity. Biochemistry (2010) 1.07
Casein kinase II phosphorylates the fragile X mental retardation protein and modulates its biological properties. Mol Cell Biol (2002) 1.06
Distinct functions of maternal and somatic Pat1 protein paralogs. RNA (2010) 1.06
Pyridostatin analogues promote telomere dysfunction and long-term growth inhibition in human cancer cells. Org Biomol Chem (2012) 1.05
Potential therapeutic interventions for fragile X syndrome. Trends Mol Med (2010) 1.05
The Role of MicroRNAs in Human Diseases. Avicenna J Med Biotechnol (2010) 1.04
Analysis of FMRP mRNA target datasets reveals highly associated mRNAs mediated by G-quadruplex structures formed via clustered WGGA sequences. Hum Mol Genet (2014) 1.03
Desmoplakin and talin2 are novel mRNA targets of fragile X-related protein-1 in cardiac muscle. Circ Res (2011) 1.00
Specific interactions of distamycin with G-quadruplex DNA. Nucleic Acids Res (2003) 1.00
Distinct domains in the CArG-box binding factor A destabilize tetraplex forms of the fragile X expanded sequence d(CGG)n. Nucleic Acids Res (2002) 0.98
Position and stability are determining factors for translation repression by an RNA G-quadruplex-forming sequence within the 5' UTR of the NRAS proto-oncogene. Biochemistry (2008) 0.98
The porphyrin TmPyP4 unfolds the extremely stable G-quadruplex in MT3-MMP mRNA and alleviates its repressive effect to enhance translation in eukaryotic cells. Nucleic Acids Res (2012) 0.97
Small regulatory RNAs in neurodevelopmental disorders. Hum Mol Genet (2009) 0.96
Crystal structure reveals specific recognition of a G-quadruplex RNA by a β-turn in the RGG motif of FMRP. Proc Natl Acad Sci U S A (2015) 0.96
Hybridization of complementary and homologous peptide nucleic acid oligomers to a guanine quadruplex-forming RNA. Biochemistry (2006) 0.95
FRAXE-associated mental retardation protein (FMR2) is an RNA-binding protein with high affinity for G-quartet RNA forming structure. Nucleic Acids Res (2009) 0.94
Arginine methylation of RNA-binding proteins regulates cell function and differentiation. Mol Reprod Dev (2012) 0.94
The GABAA receptor is an FMRP target with therapeutic potential in fragile X syndrome. Cell Cycle (2015) 0.94
Neurodegenerative diseases: quantitative predictions of protein-RNA interactions. RNA (2012) 0.94
Principles of self-organization in biological pathways: a hypothesis on the autogenous association of alpha-synuclein. Nucleic Acids Res (2013) 0.93
Generation and characterization of FMR1 knockout zebrafish. PLoS One (2009) 0.93
Bicaudal-D regulates fragile X mental retardation protein levels, motility, and function during neuronal morphogenesis. Curr Biol (2010) 0.93
Characterisation of Fmrp in zebrafish: evolutionary dynamics of the fmr1 gene. Dev Genes Evol (2005) 0.92
RNA G-Quadruplexes in the model plant species Arabidopsis thaliana: prevalence and possible functional roles. Nucleic Acids Res (2010) 0.92
U3 region in the HIV-1 genome adopts a G-quadruplex structure in its RNA and DNA sequence. Biochemistry (2014) 0.92
Expression of three zebrafish orthologs of human FMR1-related genes and their phylogenetic relationships. Dev Genes Evol (2004) 0.92
Argonaute2 suppresses Drosophila fragile X expression preventing neurogenesis and oogenesis defects. PLoS One (2009) 0.91
The fragile x mental retardation syndrome 20 years after the FMR1 gene discovery: an expanding universe of knowledge. Clin Biochem Rev (2011) 0.91
Dysregulation and restoration of translational homeostasis in fragile X syndrome. Nat Rev Neurosci (2015) 0.91
G quadruplex RNA structures in PSD-95 mRNA: potential regulators of miR-125a seed binding site accessibility. RNA (2014) 0.90
Translational repression of the disintegrin and metalloprotease ADAM10 by a stable G-quadruplex secondary structure in its 5'-untranslated region. J Biol Chem (2011) 0.90
Therapeutic Strategies in Fragile X Syndrome: From Bench to Bedside and Back. Neurotherapeutics (2015) 0.90
Ultrastructural analysis of the functional domains in FMRP using primary hippocampal mouse neurons. Neurobiol Dis (2009) 0.89
Identification and characterization of RNA guanine-quadruplex binding proteins. Nucleic Acids Res (2014) 0.89
Protein phosphatase 2A (PP2A)-specific ubiquitin ligase MID1 is a sequence-dependent regulator of translation efficiency controlling 3-phosphoinositide-dependent protein kinase-1 (PDPK-1). J Biol Chem (2011) 0.88
Functional characterization of the dendritically localized mRNA neuronatin in hippocampal neurons. PLoS One (2011) 0.88
A study of the ultrastructure of fragile-X-related proteins. Biochem J (2009) 0.88
Modeling fragile X syndrome in the Fmr1 knockout mouse. Intractable Rare Dis Res (2014) 0.88
RNA-mediated pathogenesis in fragile X-associated disorders. Neurosci Lett (2009) 0.87
Fragile X Syndrome and Alzheimer's Disease: Another story about APP and beta-amyloid. Curr Alzheimer Res (2010) 0.87
A novel role for the RNA-binding protein FXR1P in myoblasts cell-cycle progression by modulating p21/Cdkn1a/Cip1/Waf1 mRNA stability. PLoS Genet (2013) 0.87
Noncoding RNAs in mental retardation. Clin Genet (2009) 0.86
Fragile X syndrome and model organisms: identifying potential routes of therapeutic intervention. Dis Model Mech (2010) 0.85
In sickness and in health: the importance of translational regulation. Arch Dis Child (2002) 0.85
hnRNP proteins and the biogenesis of mRNA. Annu Rev Biochem (1993) 11.44
Influences of mRNA secondary structure on initiation by eukaryotic ribosomes. Proc Natl Acad Sci U S A (1986) 8.00
Monovalent cation-induced structure of telomeric DNA: the G-quartet model. Cell (1989) 7.83
Circularization of mRNA by eukaryotic translation initiation factors. Mol Cell (1998) 6.47
Telomeric DNA dimerizes by formation of guanine tetrads between hairpin loops. Nature (1989) 6.41
Turnover mechanisms of the stable yeast PGK1 mRNA. Mol Cell Biol (1995) 5.83
Circumstances and mechanisms of inhibition of translation by secondary structure in eucaryotic mRNAs. Mol Cell Biol (1989) 5.52
Inhibition of telomerase by G-quartet DNA structures. Nature (1991) 5.38
A sodium-potassium switch in the formation of four-stranded G4-DNA. Nature (1990) 5.35
A mouse cytoplasmic exoribonuclease (mXRN1p) with preference for G4 tetraplex substrates. J Cell Biol (1997) 4.93
FMR1 protein: conserved RNP family domains and selective RNA binding. Science (1993) 4.77
Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits. Proc Natl Acad Sci U S A (1997) 4.73
The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation. Nat Genet (1993) 4.57
Quadruplex structure of Oxytricha telomeric DNA oligonucleotides. Nature (1992) 4.24
DNA tetraplex formation in the control region of c-myc. Nucleic Acids Res (1998) 4.09
Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation. Proc Natl Acad Sci U S A (1997) 4.03
Crystal structure of four-stranded Oxytricha telomeric DNA. Nature (1992) 3.96
Evidence that fragile X mental retardation protein is a negative regulator of translation. Hum Mol Genet (2001) 3.91
FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association. Mol Cell (1997) 3.71
The fragile X mental retardation protein inhibits translation via interacting with mRNA. Nucleic Acids Res (2001) 3.18
Evidence for interstrand quadruplex formation in the dimerization of human immunodeficiency virus 1 genomic RNA. Proc Natl Acad Sci U S A (1993) 3.02
Essential role for KH domains in RNA binding: impaired RNA binding by a mutation in the KH domain of FMR1 that causes fragile X syndrome. Cell (1994) 3.01
The fragile X syndrome d(CGG)n nucleotide repeats form a stable tetrahelical structure. Proc Natl Acad Sci U S A (1994) 2.72
The high-resolution crystal structure of a parallel-stranded guanine tetraplex. Science (1994) 2.64
The fragile X mental retardation protein is a ribonucleoprotein containing both nuclear localization and nuclear export signals. Hum Mol Genet (1996) 2.49
Mechanism of carcinogenesis by RNA tumor viruses. 3. Formation of RNA, DNA complex and duplex DNA molecules by the DNA polymerase (s) of avian myeloblastosis virus. Proc Natl Acad Sci U S A (1970) 2.37
Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them. Mol Cell Biol (1996) 2.26
Iron regulatory protein prevents binding of the 43S translation pre-initiation complex to ferritin and eALAS mRNAs. EMBO J (1994) 2.22
Characterization of dFMR1, a Drosophila melanogaster homolog of the fragile X mental retardation protein. Mol Cell Biol (2000) 2.18
Phylogeny of rapidly growing members of the genus Mycobacterium. Int J Syst Bacteriol (1992) 2.18
A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P. Proc Natl Acad Sci U S A (2001) 2.17
General RNA binding proteins render translation cap dependent. EMBO J (1996) 2.15
Isolation of an FMRP-associated messenger ribonucleoprotein particle and identification of nucleolin and the fragile X-related proteins as components of the complex. Mol Cell Biol (1999) 2.13
Understanding the molecular basis of fragile X syndrome. Hum Mol Genet (2000) 2.13
The fragile X mental retardation protein is associated with poly(A)+ mRNA in actively translating polyribosomes. Hum Mol Genet (1997) 2.08
The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2. EMBO J (1995) 2.05
Human and murine FMR-1: alternative splicing and translational initiation downstream of the CGG-repeat. Nat Genet (1993) 1.95
Identification of an RNA binding site for human thymidylate synthase. Proc Natl Acad Sci U S A (1993) 1.94
Solution structure of an unusually stable RNA tetraplex containing G- and U-quartet structures. Biochemistry (1992) 1.88
Alternative splicing of exon 14 determines nuclear or cytoplasmic localisation of fmr1 protein isoforms. Hum Mol Genet (1996) 1.74
Tetramerization of an RNA oligonucleotide containing a GGGG sequence. Nature (1991) 1.69
Purified recombinant Fmrp exhibits selective RNA binding as an intrinsic property of the fragile X mental retardation protein. J Biol Chem (1998) 1.63
Probing RNA structure and RNA-ligand complexes with chemical probes. Methods Enzymol (2000) 1.63
Induction of duplex to G-quadruplex transition in the c-myc promoter region by a small molecule. J Biol Chem (2000) 1.54
Modulation of AUUUA response element binding by heterogeneous nuclear ribonucleoprotein A1 in human T lymphocytes. The roles of cytoplasmic location, transcription, and phosphorylation. J Biol Chem (1997) 1.50
A guanosine quadruplex and two stable hairpins flank a major cleavage site in insulin-like growth factor II mRNA. Nucleic Acids Res (1994) 1.40
A novel RNA-binding nuclear protein that interacts with the fragile X mental retardation (FMR1) protein. Hum Mol Genet (1999) 1.38
KH domains within the FMR1 sequence suggest that fragile X syndrome stems from a defect in RNA metabolism. Trends Biochem Sci (1993) 1.37
Participation of the human p53 3'UTR in translational repression and activation following gamma-irradiation. EMBO J (1997) 1.37
Different targets for the fragile X-related proteins revealed by their distinct nuclear localizations. Hum Mol Genet (1999) 1.35
Dihydrofolate reductase protein inhibits its own translation by binding to dihydrofolate reductase mRNA sequences within the coding region. Biochemistry (1997) 1.30
The stability of polypurine tetraplexes in the presence of mono- and divalent cations. Nucleic Acids Res (1990) 1.26
Mechanism of inhibition of HIV-1 integrase by G-tetrad-forming oligonucleotides in Vitro. J Biol Chem (2000) 1.18
Characterization of a cis-acting regulatory element in the protein coding region of thymidylate synthase mRNA. Nucleic Acids Res (2000) 1.18
Long-range RNA interaction of two sequence elements required for endonucleolytic cleavage of human insulin-like growth factor II mRNAs. Mol Cell Biol (1995) 1.18
Preferential binding of fd gene 5 protein to tetraplex nucleic acid structures. J Mol Biol (2000) 1.18
Gene disruption of a G4-DNA-dependent nuclease in yeast leads to cellular senescence and telomere shortening. Proc Natl Acad Sci U S A (1995) 1.11
RNAs that interact with the fragile X syndrome RNA binding protein FMRP. Biochem Biophys Res Commun (2000) 1.03
The expression of E.coli threonyl-tRNA synthetase is regulated at the translational level by symmetrical operator-repressor interactions. EMBO J (1996) 0.88
RNA quadruplex containing G and A. Nucleic Acids Symp Ser (1995) 0.84
Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion. Science (1996) 11.59
Probing the structure of RNAs in solution. Nucleic Acids Res (1987) 7.62
Instability of a 550-base pair DNA segment and abnormal methylation in fragile X syndrome. Science (1991) 7.16
Ovalbumin gene is split in chicken DNA. Nature (1977) 7.05
Clinical and genetic abnormalities in patients with Friedreich's ataxia. N Engl J Med (1996) 6.57
The complete nucleotide sequence of the ribosomal 16-S RNA from Excherichia coli. Experimental details and cistron heterogeneities. Eur J Biochem (1979) 6.08
Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters. Nature (1993) 5.05
DNA methylation: organ specific variations in the methylation pattern within and around ovalbumin and other chicken genes. Nucleic Acids Res (1979) 4.81
The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation. Nat Genet (1993) 4.57
The topography of the 5' end of 16-S RNA in the presence and absence of ribosomal proteins S4 and S20. Eur J Biochem (1980) 4.22
Genetic mapping of the human X chromosome by using restriction fragment length polymorphisms. Proc Natl Acad Sci U S A (1984) 4.22
Alpha-amanitin: a specific inhibitor of one of two DNA-pendent RNA polymerase activities from calf thymus. Biochem Biophys Res Commun (1970) 4.16
The ovalbumin gene family: structure of the X gene and evolution of duplicated split genes. Cell (1980) 4.14
Functional sites in the 5' region of human immunodeficiency virus type 1 RNA form defined structural domains. J Mol Biol (1993) 4.08
Identification of the primary site of the human immunodeficiency virus type 1 RNA dimerization in vitro. Proc Natl Acad Sci U S A (1994) 4.07
Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3. Neuron (1997) 3.73
Evidence for tertiary structural RNA-RNA interactions within the protein S4 binding site at the 5'-end of 16S ribosomal RNA of Escherichia coli.+. Nucleic Acids Res (1975) 3.67
A gene mutated in X-linked myotubular myopathy defines a new putative tyrosine phosphatase family conserved in yeast. Nat Genet (1996) 3.67
A gene deleted in Kallmann's syndrome shares homology with neural cell adhesion and axonal path-finding molecules. Nature (1991) 3.59
The sequence of the ribosomal 16S RNA from Proteus vulgaris. Sequence comparison with E. coli 16S RNA and its use in secondary model building. Nucleic Acids Res (1981) 3.43
Report of the committee on the genetic constitution of the X chromosome. Cytogenet Cell Genet (1989) 3.37
A topographical study of the 5'-region of 16 S rna of Escherichia coli in the presence and absence of protein S4. FEBS Lett (1977) 3.31
Cloning of the gene for spinocerebellar ataxia 2 reveals a locus with high sensitivity to expanded CAG/glutamine repeats. Nat Genet (1996) 3.26
Initiation of reverse transcription of HIV-1: secondary structure of the HIV-1 RNA/tRNA(3Lys) (template/primer). J Mol Biol (1995) 3.23
Mutations in the kinase Rsk-2 associated with Coffin-Lowry syndrome. Nature (1996) 3.21
The sequence of Escherichia coli ribosomal 16 S RNA determined by new rapid gel methods. FEBS Lett (1978) 3.19
Frataxin is reduced in Friedreich ataxia patients and is associated with mitochondrial membranes. Hum Mol Genet (1997) 3.11
Prenatal diagnosis and carrier detection of Duchenne muscular dystrophy with closely linked RFLPs. Lancet (1985) 3.08
Modified nucleotides of tRNA(3Lys) modulate primer/template loop-loop interaction in the initiation complex of HIV-1 reverse transcription. J Biol Chem (1993) 2.95
Dimerization of human immunodeficiency virus (type 1) RNA: stimulation by cations and possible mechanism. Nucleic Acids Res (1991) 2.94
The ovalbumin gene family: hormonal control of X and Y gene transcription and mRNA accumulation. Cell (1981) 2.91
The telomeric region of the human X chromosome long arm: presence of a highly polymorphic DNA marker and analysis of recombination frequency. Proc Natl Acad Sci U S A (1985) 2.88
Measurements of energetic particle radiation in transit to Mars on the Mars Science Laboratory. Science (2013) 2.83
Cloning of the SCA7 gene reveals a highly unstable CAG repeat expansion. Nat Genet (1997) 2.77
The structure of threonyl-tRNA synthetase-tRNA(Thr) complex enlightens its repressor activity and reveals an essential zinc ion in the active site. Cell (1999) 2.74
The determination of the primary structure of the 16S ribosomal RNA of Escherichia coli. 2. Nucleotide sequences of products from partial enzymatic hydrolysis. Biochimie (1972) 2.74
Mutational analysis of the bipartite dimer linkage structure of human immunodeficiency virus type 1 genomic RNA. J Biol Chem (1994) 2.71
Origin of the expansion mutation in myotonic dystrophy. Nat Genet (1993) 2.70
Report of the Committee on Human Gene Mapping by Recombinant DNA Techniques. Cytogenet Cell Genet (1985) 2.70
Monogenic causes of X-linked mental retardation. Nat Rev Genet (2001) 2.68
Primary sequence of the 16S ribosomal RNA of Escherichia coli. Nucleic Acids Res (1975) 2.67
Organization of coding and intervening sequences in the chicken ovalbumin split gene. Cell (1978) 2.61
A general secondary-structure model for procaryotic and eucaryotic RNAs from the small ribosomal subunits. Eur J Biochem (1981) 2.60
DNA probe localization at 18p113 band by in situ hybridization and identification of a small supernumerary chromosome. Hum Genet (1985) 2.59
The determination of the primary structure of the 16S ribosomal RNA of Escherichia coli. III. Further studies. Biochimie (1975) 2.57
An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita. Nature (1994) 2.57
A loop-loop "kissing" complex is the essential part of the dimer linkage of genomic HIV-1 RNA. Proc Natl Acad Sci U S A (1996) 2.56
Mutations in the DAX-1 gene give rise to both X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism. Nature (1994) 2.49
Isolation and characterization of cDNA clones for human skeletal muscle alpha actin. Nucleic Acids Res (1983) 2.45
Location of ribosomal protein binding sites on 16S ribosomal RNA. Proc Natl Acad Sci U S A (1972) 2.43
The role of exportin-t in selective nuclear export of mature tRNAs. EMBO J (1998) 2.40
tRNAs as primer of reverse transcriptases. Biochimie (1995) 2.37
The ovalbumin gene region: common features in the organisation of three genes expressed in chicken oviduct under hormonal control. Nature (1979) 2.35
A dual role of the putative RNA dimerization initiation site of human immunodeficiency virus type 1 in genomic RNA packaging and proviral DNA synthesis. J Virol (1996) 2.33
Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form. Nat Genet (1995) 2.33
Structural organization of the 16S ribosomal RNA from E. coli. Topography and secondary structure. Nucleic Acids Res (1981) 2.32
DNA methylation: correlation with DNase I sensitivity of chicken ovalbumin and conalbumin chromatin. Nucleic Acids Res (1979) 2.31
Adenovirus as an expression vector in muscle cells in vivo. Proc Natl Acad Sci U S A (1992) 2.30
Close linkage of fragile X-mental retardation syndrome to haemophilia B and transmission through a normal male. Nature (1984) 2.28
Regional localization on the human X chromosome and polymorphism of the coagulation factor IX gene (hemophilia B locus). Proc Natl Acad Sci U S A (1984) 2.23
Rapid antibody test for fragile X syndrome. Lancet (1995) 2.22
Dimerization of human immunodeficiency virus type 1 RNA involves sequences located upstream of the splice donor site. Nucleic Acids Res (1994) 2.21
Partial nucleotide sequence of 16S ribosomal RNA from E. coli. Nat New Biol (1972) 2.17
A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P. Proc Natl Acad Sci U S A (2001) 2.17
Nucleotide sequences present within the 16S ribosomal RNA of Escherichia coli. Nature (1970) 2.15
Location and characteristics of ribosomal protein binding sites in the 16S RNA of Escherichia coli. Nucleic Acids Res (1975) 2.15
Abnormal pattern detected in fragile-X patients by pulsed-field gel electrophoresis. Nature (1991) 2.13
Friedreich ataxia in Louisiana Acadians: demonstration of a founder effect by analysis of microsatellite-generated extended haplotypes. Am J Hum Genet (1992) 2.10
Spectrophotometric determination of protein concentration in cell extracts containing tRNA's and rRNA's. Anal Biochem (1973) 2.09
Carrier detection of Hemophilia B by using a restriction site polymorphism associated with the coagulation Factor IX gene. J Clin Invest (1984) 2.07
Transfer RNA-mediated editing in threonyl-tRNA synthetase. The class II solution to the double discrimination problem. Cell (2000) 2.05
Ataxia with isolated vitamin E deficiency is caused by mutations in the alpha-tocopherol transfer protein. Nat Genet (1995) 2.03
Dimerization of retroviral genomic RNAs: structural and functional implications. Biochimie (1996) 2.03
Friedreich's ataxia: point mutations and clinical presentation of compound heterozygotes. Ann Neurol (1999) 2.02
Recent progress in the determination of the primary sequence of the 16 S RNA of Escherichia coli. FEBS Lett (1977) 2.01
Sequence analysis of the 3'-T1 oligonucleotide of 16S ribosomal RNA from Escherichia coli. FEBS Lett (1974) 1.93
A DNA fragment from the human X chromosome short arm which detects a partially homologous sequence on the Y chromosomes long arm. Nucleic Acids Res (1984) 1.93
Characterization of a set of X-linked sequences and of a panel of somatic cell hybrids useful for the regional mapping of the human X chromosome. Hum Genet (1986) 1.92
Myotubularin, a phosphatase deficient in myotubular myopathy, acts on phosphatidylinositol 3-kinase and phosphatidylinositol 3-phosphate pathway. Hum Mol Genet (2000) 1.92
Effect of dimerization on the conformation of the encapsidation Psi domain of Moloney murine leukemia virus RNA. J Mol Biol (1992) 1.89