PubRank

Joseph A Adams

Author PubWeight™ 49.20‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A sliding docking interaction is essential for sequential and processive phosphorylation of an SR protein by SRPK1. Mol Cell 2008 2.29
2 Interplay between SRPK and Clk/Sty kinases in phosphorylation of the splicing factor ASF/SF2 is regulated by a docking motif in ASF/SF2. Mol Cell 2005 2.11
3 The Akt-SRPK-SR axis constitutes a major pathway in transducing EGF signaling to regulate alternative splicing in the nucleus. Mol Cell 2012 1.83
4 Processive phosphorylation of alternative splicing factor/splicing factor 2. Proc Natl Acad Sci U S A 2003 1.75
5 Regulation of SR protein phosphorylation and alternative splicing by modulating kinetic interactions of SRPK1 with molecular chaperones. Genes Dev 2009 1.65
6 Phosphorylation reaction in cAPK protein kinase-free energy quantum mechanical/molecular mechanics simulations. J Phys Chem B 2007 1.55
7 Phosphorylation driven motions in the COOH-terminal Src kinase, CSK, revealed through enhanced hydrogen-deuterium exchange and mass spectrometry (DXMS). J Mol Biol 2002 1.53
8 Mass spectrometric and kinetic analysis of ASF/SF2 phosphorylation by SRPK1 and Clk/Sty. J Biol Chem 2005 1.43
9 Regulated cellular partitioning of SR protein-specific kinases in mammalian cells. Mol Biol Cell 2005 1.42
10 Phosphorylation mechanism and structure of serine-arginine protein kinases. FEBS J 2011 1.30
11 The role of the putative catalytic base in the phosphoryl transfer reaction in a protein kinase: first-principles calculations. J Am Chem Soc 2003 1.26
12 Ligand-induced global transitions in the catalytic domain of protein kinase A. Proc Natl Acad Sci U S A 2009 1.25
13 Ordered multi-site phosphorylation of the splicing factor ASF/SF2 by SRPK1. J Mol Biol 2007 1.19
14 Coupled motions in the SH2 and kinase domains of Csk control Src phosphorylation. J Mol Biol 2005 1.18
15 Adaptable molecular interactions guide phosphorylation of the SR protein ASF/SF2 by SRPK1. J Mol Biol 2008 1.17
16 Structural basis for the regulation of protein kinase A by activation loop phosphorylation. J Biol Chem 2012 1.14
17 Structural basis for peptide binding in protein kinase A. Role of glutamic acid 203 and tyrosine 204 in the peptide-positioning loop. J Biol Chem 2002 1.08
18 Partitioning RS domain phosphorylation in an SR protein through the CLK and SRPK protein kinases. J Mol Biol 2013 1.08
19 Coupling phosphoryl transfer and substrate interactions in protein kinases. Biochim Biophys Acta 2005 1.06
20 A novel disulfide bond in the SH2 Domain of the C-terminal Src kinase controls catalytic activity. J Mol Biol 2006 1.03
21 Dynamic coupling between the SH2 domain and active site of the COOH terminal Src kinase, Csk. J Mol Biol 2004 1.02
22 Proteins at work: a combined small angle X-RAY scattering and theoretical determination of the multiple structures involved on the protein kinase functional landscape. J Biol Chem 2010 1.02
23 Regiospecific phosphorylation control of the SR protein ASF/SF2 by SRPK1. J Mol Biol 2009 0.99
24 Communication pathways between the nucleotide pocket and distal regulatory sites in protein kinases. Acc Chem Res 2004 0.98
25 Phosphoryl transfer step in the C-terminal Src kinase controls Src recognition. J Biol Chem 2004 0.96
26 Nucleotide-induced conformational changes in the Saccharomyces cerevisiae SR protein kinase, Sky1p, revealed by X-ray crystallography. Biochemistry 2003 0.95
27 Mechanism of dephosphorylation of the SR protein ASF/SF2 by protein phosphatase 1. J Mol Biol 2010 0.94
28 Applying the brakes to multisite SR protein phosphorylation: substrate-induced effects on the splicing kinase SRPK1. Biochemistry 2011 0.91
29 SR protein kinase 1 is resilient to inactivation. Structure 2007 0.90
30 The RGG domain of Npl3p recruits Sky1p through docking interactions. J Mol Biol 2006 0.89
31 C6 pyridinium ceramide influences alternative pre-mRNA splicing by inhibiting protein phosphatase-1. Nucleic Acids Res 2011 0.88
32 Mechanistic insights into Sky1p, a yeast homologue of the mammalian SR protein kinases. Biochemistry 2002 0.87
33 Nucleotide release sequences in the protein kinase SRPK1 accelerate substrate phosphorylation. Biochemistry 2012 0.87
34 SRC tail phosphorylation is limited by structural changes in the regulatory tyrosine kinase Csk. J Biol Chem 2006 0.86
35 Chemical clamping allows for efficient phosphorylation of the RNA carrier protein Npl3. J Biol Chem 2004 0.85
36 Regulating SR protein phosphorylation through regions outside the kinase domain of SRPK1. J Mol Biol 2011 0.85
37 Probing the nucleotide binding domain of the osmoregulator EnvZ using fluorescent nucleotide derivatives. Biochemistry 2002 0.84
38 Distal loop flexibility of a regulatory domain modulates dynamics and activity of C-terminal SRC kinase (csk). PLoS Comput Biol 2013 0.84
39 Novel destabilization of nucleotide binding by the gamma phosphate of ATP in the yeast SR protein kinase Sky1p. Biochemistry 2003 0.83
40 Substrate-specific reorganization of the conformational ensemble of CSK implicates novel modes of kinase function. PLoS Comput Biol 2012 0.81
41 Splicing kinase SRPK1 conforms to the landscape of its SR protein substrate. Biochemistry 2013 0.79
42 Structure and activity of CPNGRC: a modified CD13/APN peptidic homing motif. Chem Biol Drug Des 2010 0.78
43 Recruiting a silent partner for activation of the protein kinase SRPK1. Biochemistry 2014 0.77
44 Correction: Theoretical Insights Reveal Novel Motions in Csk's SH3 Domain That Control Kinase Activation. PLoS One 2015 0.75
45 Transferred NOE and saturation transfer difference NMR studies of novobiocin binding to EnvZ suggest binding mode similar to DNA gyrase. Chem Biol Drug Des 2007 0.75