Published in PLoS One on September 26, 2013
Micromanaging cardiac regeneration: Targeted delivery of microRNAs for cardiac repair and regeneration. World J Cardiol (2016) 0.78
Targeted antiangiogenesis gene therapy using targeted cationic microbubbles conjugated with CD105 antibody compared with untargeted cationic and neutral microbubbles. Theranostics (2015) 0.78
Ultrasound-targeted microbubble destruction (UTMD) assisted delivery of shRNA against PHD2 into H9C2 cells. PLoS One (2015) 0.76
Monitoring/Imaging and Regenerative Agents for Enhancing Tissue Engineering Characterization and Therapies. Ann Biomed Eng (2015) 0.75
Localized Delivery of shRNA against PHD2 Protects the Heart from Acute Myocardial Infarction through Ultrasound-Targeted Cationic Microbubble Destruction. Theranostics (2017) 0.75
Nanomaterials incorporated ultrasound contrast agents for cancer theranostics. Cancer Biol Med (2016) 0.75
Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response. Nat Med (2006) 13.51
Polyethylenimine-based non-viral gene delivery systems. Eur J Pharm Biopharm (2005) 2.88
Mechanism of tumor-targeted delivery of macromolecular drugs, including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS. J Control Release (2001) 2.44
Progress in developing cationic vectors for non-viral systemic gene therapy against cancer. Biomaterials (2008) 2.43
Microbubble size isolation by differential centrifugation. J Colloid Interface Sci (2008) 2.40
Transfection of a reporter plasmid into cultured cells by sonoporation in vitro. Ultrasound Med Biol (1997) 2.05
Ultrasound-targeted microbubble destruction can repeatedly direct highly specific plasmid expression to the heart. Circulation (2003) 2.03
Polyethylenimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells. J Biol Chem (1998) 1.98
Ultrasound, cavitation bubbles and their interaction with cells. Adv Drug Deliv Rev (2008) 1.93
Targeted tissue transfection with ultrasound destruction of plasmid-bearing cationic microbubbles. Ultrasound Med Biol (2003) 1.88
Influence of lipid shell physicochemical properties on ultrasound-induced microbubble destruction. IEEE Trans Ultrason Ferroelectr Freq Control (2005) 1.77
Ultrasound radiation force enables targeted deposition of model drug carriers loaded on microbubbles. J Control Release (2005) 1.68
Ultrasound-microbubble-mediated intercellular adhesion molecule-1 small interfering ribonucleic acid transfection attenuates neointimal formation after arterial injury in mice. J Am Coll Cardiol (2010) 1.68
Sonoporation by ultrasound-activated microbubble contrast agents: effect of acoustic exposure parameters on cell membrane permeability and cell viability. Ultrasound Med Biol (2008) 1.63
Efficient gene delivery to pancreatic islets with ultrasonic microbubble destruction technology. Proc Natl Acad Sci U S A (2006) 1.57
Microbubble-enhanced ultrasound for vascular gene delivery. Gene Ther (2000) 1.54
Lateral phase separation in lipid-coated microbubbles. Langmuir (2006) 1.52
Poly(ethylenimine)-mediated transfection: a new paradigm for gene delivery. J Biomed Mater Res (2000) 1.50
Physical parameters influencing optimization of ultrasound-mediated DNA transfection. Ultrasound Med Biol (2004) 1.37
Local drug and gene delivery through microbubbles. Prog Cardiovasc Dis (2001) 1.30
Design and evaluation of doxorubicin-containing microbubbles for ultrasound-triggered doxorubicin delivery: cytotoxicity and mechanisms involved. Mol Ther (2009) 1.27
Cavitation bioeffects. Crit Rev Biomed Eng (2006) 1.25
Augmentation of cardiac protein delivery using ultrasound targeted microbubble destruction. Ultrasound Med Biol (2005) 1.23
DNA-loaded albumin microbubbles enhance ultrasound-mediated transfection in vitro. Ultrasound Med Biol (2002) 1.22
DNA and polylysine adsorption and multilayer construction onto cationic lipid-coated microbubbles. Langmuir (2007) 1.16
Advances in ultrasound mediated gene therapy using microbubble contrast agents. Theranostics (2012) 1.15
Ultrasound-responsive polymer-coated microbubbles that bind and protect DNA. Langmuir (2006) 1.12
Polyplex-microbubble hybrids for ultrasound-guided plasmid DNA delivery to solid tumors. J Control Release (2011) 1.06
The correlation between acoustic cavitation and sonoporation involved in ultrasound-mediated DNA transfection with polyethylenimine (PEI) in vitro. J Control Release (2010) 1.06
Analysis of in vitro transfection by sonoporation using cationic and neutral microbubbles. Ultrasound Med Biol (2010) 1.04
Cationic versus neutral microbubbles for ultrasound-mediated gene delivery in cancer. Radiology (2012) 1.03
Noninvasive and targeted gene delivery into the brain using microbubble-facilitated focused ultrasound. PLoS One (2013) 1.01
Studies on neutral, cationic and biotinylated cationic microbubbles in enhancing ultrasound-mediated gene delivery in vitro and in vivo. Acta Biomater (2011) 1.00
Targeted gene delivery in tumor xenografts by the combination of ultrasound-targeted microbubble destruction and polyethylenimine to inhibit survivin gene expression and induce apoptosis. J Exp Clin Cancer Res (2010) 0.97
Self-assembled magnetic theranostic nanoparticles for highly sensitive MRI of minicircle DNA delivery. Nanoscale (2012) 0.88
Synergistic effect of ultrasound and PEI on DNA transfection in vitro. J Control Release (2006) 0.87
mRNA-Lipoplex loaded microbubble contrast agents for ultrasound-assisted transfection of dendritic cells. Biomaterials (2011) 0.87
Synergistic effects of sonoporation and taurolidin/TRAIL on apoptosis in human fibrosarcoma. Ultrasound Med Biol (2010) 0.86
The use of cationic microbubbles to improve ultrasound-targeted gene delivery to the ischemic myocardium. Biomaterials (2012) 0.86
Ultrasonic imaging of endothelial CD81 expression using CD81-targeted contrast agents in in vitro and in vivo studies. Ultrasound Med Biol (2012) 0.82
A composite gene delivery system consisting of polyethylenimine and an amphipathic peptide KALA. J Gene Med (2006) 0.81
Evaluation of different buffers on plasmid DNA encapsulation into PLGA microparticles. Int J Pharm (2008) 0.81
Bioreducible and acid-labile poly(amido amine)s for efficient gene delivery. Int J Nanomedicine (2012) 0.77
Safe and efficient gene therapy--delivery makes all the difference. Cancer Biol Ther (2008) 0.76
Oligobenzylethylenimine enriches linear polyethylenimine with a pH-sensitive membrane-disruptive property and leads to enhanced gene delivery activity. Acta Biomater (2012) 0.76
Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer. Cancer Cell (2003) 8.11
Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies. Curr Biol (2004) 7.59
Highly multiplexed molecular inversion probe genotyping: over 10,000 targeted SNPs genotyped in a single tube assay. Genome Res (2005) 6.32
Resequencing of 31 wild and cultivated soybean genomes identifies patterns of genetic diversity and selection. Nat Genet (2010) 5.20
Single-cell exome sequencing and monoclonal evolution of a JAK2-negative myeloproliferative neoplasm. Cell (2012) 5.16
Resequencing 50 accessions of cultivated and wild rice yields markers for identifying agronomically important genes. Nat Biotechnol (2011) 4.84
Cre/loxP-mediated inactivation of the murine Pten tumor suppressor gene. Genesis (2002) 4.23
Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion. Cancer Cell (2003) 3.87
Maize HapMap2 identifies extant variation from a genome in flux. Nat Genet (2012) 3.74
Template-based protein structure modeling using the RaptorX web server. Nat Protoc (2012) 3.68
Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery. Nucleic Acids Res (2011) 3.05
PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry. Proc Natl Acad Sci U S A (2005) 2.93
The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line. Nat Biotechnol (2011) 2.87
Draft genome of the wheat A-genome progenitor Triticum urartu. Nature (2013) 2.86
Genome sequence of foxtail millet (Setaria italica) provides insights into grass evolution and biofuel potential. Nat Biotechnol (2012) 2.82
Apatinib for chemotherapy-refractory advanced metastatic gastric cancer: results from a randomized, placebo-controlled, parallel-arm, phase II trial. J Clin Oncol (2013) 2.69
The PSA(-/lo) prostate cancer cell population harbors self-renewing long-term tumor-propagating cells that resist castration. Cell Stem Cell (2012) 2.69
Genetic characterization of Nipah virus, Bangladesh, 2004. Emerg Infect Dis (2005) 2.62
Network model of survival signaling in large granular lymphocyte leukemia. Proc Natl Acad Sci U S A (2008) 2.60
How does the New Cooperative Medical Scheme influence health service utilization? A study in two provinces in rural China. BMC Health Serv Res (2010) 2.58
Sequencing and automated whole-genome optical mapping of the genome of a domestic goat (Capra hircus). Nat Biotechnol (2012) 2.45
Conditional loss of PTEN leads to precocious development and neoplasia in the mammary gland. Development (2002) 2.42
T-cell and natural killer-cell large granular lymphocyte leukemia neoplasias. Leuk Lymphoma (2011) 2.37
Multiple genes for essential-hypertension susceptibility on chromosome 1q. Am J Hum Genet (2006) 2.34
NKX3.1 stabilizes p53, inhibits AKT activation, and blocks prostate cancer initiation caused by PTEN loss. Cancer Cell (2006) 2.29
Thermomechanics of the shape memory effect in polymers for biomedical applications. J Biomed Mater Res A (2005) 2.17
Bioeffects considerations for diagnostic ultrasound contrast agents. J Ultrasound Med (2008) 2.16
PTEN dosage is essential for neurofibroma development and malignant transformation. Proc Natl Acad Sci U S A (2009) 2.07
Ulinastatin is a novel candidate drug for sepsis and secondary acute lung injury, evidence from an optimized CLP rat model. Int Immunopharmacol (2013) 2.06
A critical role of erythropoietin receptor in neurogenesis and post-stroke recovery. J Neurosci (2006) 2.04
Variability of antibiotic concentrations in critically ill patients receiving continuous renal replacement therapy: a multicentre pharmacokinetic study. Crit Care Med (2012) 2.04
Rapamycin ameliorates proteinuria-associated tubulointerstitial inflammation and fibrosis in experimental membranous nephropathy. J Am Soc Nephrol (2005) 2.00
Unconstrained recovery characterization of shape-memory polymer networks for cardiovascular applications. Biomaterials (2007) 1.96
Major submissions tool developments at the European Nucleotide Archive. Nucleic Acids Res (2011) 1.94
Elevated phosphatidylinositol 3,4,5-trisphosphate in glia triggers cell-autonomous membrane wrapping and myelination. J Neurosci (2010) 1.93
Purple acid phosphatases of Arabidopsis thaliana. Comparative analysis and differential regulation by phosphate deprivation. J Biol Chem (2002) 1.93
Ultrasound-mediated tumor imaging and nanotherapy using drug loaded, block copolymer stabilized perfluorocarbon nanoemulsions. J Control Release (2011) 1.89
Deletion of the neuron-specific protein delta-catenin leads to severe cognitive and synaptic dysfunction. Curr Biol (2004) 1.80
Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis. J Neurosci (2009) 1.80
Strong, Tailored, Biocompatible Shape-Memory Polymer Networks. Adv Funct Mater (2008) 1.77
Evidence of connective tissue involvement in acupuncture. FASEB J (2002) 1.75
Maternal embryonic leucine zipper kinase (MELK) regulates multipotent neural progenitor proliferation. J Cell Biol (2005) 1.74
Comparisons of image quality and radiation dose between iterative reconstruction and filtered back projection reconstruction algorithms in 256-MDCT coronary angiography. AJR Am J Roentgenol (2012) 1.73
3D noncontrast MR angiography of the distal lower extremities using flow-sensitive dephasing (FSD)-prepared balanced SSFP. Magn Reson Med (2009) 1.72
8q24 and prostate cancer: association with advanced disease and meta-analysis. Eur J Hum Genet (2008) 1.72
Acoustically-active microbubbles conjugated to liposomes: characterization of a proposed drug delivery vehicle. J Control Release (2006) 1.70
L-fucose utilization provides Campylobacter jejuni with a competitive advantage. Proc Natl Acad Sci U S A (2011) 1.68
GJB2 mutation spectrum in 2,063 Chinese patients with nonsyndromic hearing impairment. J Transl Med (2009) 1.66
Radiation dose reduction in computed tomography: techniques and future perspective. Imaging Med (2009) 1.65
Genetic background controls tumor development in PTEN-deficient mice. Cancer Res (2006) 1.63
Telbivudine or lamivudine use in late pregnancy safely reduces perinatal transmission of hepatitis B virus in real-life practice. Hepatology (2014) 1.62
Contrast-enhanced whole-heart coronary magnetic resonance angiography at 3.0-T: a comparative study with X-ray angiography in a single center. J Am Coll Cardiol (2009) 1.61
Electromagnetic imaging methods for nondestructive evaluation applications. Sensors (Basel) (2011) 1.59
SUMO1 modification of PTEN regulates tumorigenesis by controlling its association with the plasma membrane. Nat Commun (2012) 1.58
Lithium activates the Wnt and phosphatidylinositol 3-kinase Akt signaling pathways to promote cell survival in the absence of soluble survival factors. Am J Physiol Renal Physiol (2004) 1.58
Hexokinase regulates Bax-mediated mitochondrial membrane injury following ischemic stress. Kidney Int (2011) 1.58
An artificial right ventricle for failing fontan: in vitro and computational study. Ann Thorac Surg (2009) 1.58
How affordable are tuberculosis diagnosis and treatment in rural China? An analysis from community and tuberculosis patient perspectives. Trop Med Int Health (2007) 1.57
Essential role of AKT-1/protein kinase B alpha in PTEN-controlled tumorigenesis. Mol Cell Biol (2002) 1.57
Changes in the structure-function relationship of elastin and its impact on the proximal pulmonary arterial mechanics of hypertensive calves. Am J Physiol Heart Circ Physiol (2008) 1.54
Development of two avidity-based assays to detect recent HIV type 1 seroconversion using a multisubtype gp41 recombinant protein. AIDS Res Hum Retroviruses (2010) 1.53
Randomized phase II trial of lyophilized strawberries in patients with dysplastic precancerous lesions of the esophagus. Cancer Prev Res (Phila) (2011) 1.53
Discovery of marinopyrrole A (maritoclax) as a selective Mcl-1 antagonist that overcomes ABT-737 resistance by binding to and targeting Mcl-1 for proteasomal degradation. J Biol Chem (2012) 1.53
A facile system for genetic incorporation of two different noncanonical amino acids into one protein in Escherichia coli. Angew Chem Int Ed Engl (2010) 1.52
Architecture of an RNA polymerase II transcription pre-initiation complex. Science (2013) 1.52
Dynamical and structural analysis of a T cell survival network identifies novel candidate therapeutic targets for large granular lymphocyte leukemia. PLoS Comput Biol (2011) 1.51
Percent fat mass is inversely associated with bone mass and hip geometry in rural Chinese adolescents. J Bone Miner Res (2010) 1.47
Podocalyxin variants and risk of prostate cancer and tumor aggressiveness. Hum Mol Genet (2006) 1.46
An optimized small molecule inhibitor cocktail supports long-term maintenance of human embryonic stem cells. Nat Commun (2011) 1.45
Molecular profiling of LGL leukemia reveals role of sphingolipid signaling in survival of cytotoxic lymphocytes. Blood (2008) 1.45
Hsp27 inhibits Bax activation and apoptosis via a phosphatidylinositol 3-kinase-dependent mechanism. J Biol Chem (2008) 1.44
Identification of natural coumarin compounds that rescue defective DeltaF508-CFTR chloride channel gating. Clin Exp Pharmacol Physiol (2008) 1.43
A mechanism-based inactivator for histone demethylase LSD1. J Am Chem Soc (2006) 1.43
Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis. BMC Genomics (2008) 1.43
[Ln2(C2O4)2(pyzc)2(H2O)2]n[Ln = Pr (1), Er (2)]: novel two-dimensional lanthanide coordination polymers with 2-pyrazinecarboxylate and oxalate. Inorg Chem (2006) 1.41
Assembly information services in the European Nucleotide Archive. Nucleic Acids Res (2013) 1.40
A cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells. Nat Immunol (2011) 1.39
c-MYC-regulated miR-23a/24-2/27a cluster promotes mammary carcinoma cell invasion and hepatic metastasis by targeting Sprouty2. J Biol Chem (2013) 1.37
Laminar and compartmental regulation of dendritic growth in mature cortex. Nat Neurosci (2009) 1.37
Quantification of hemodynamic wall shear stress in patients with bicuspid aortic valve using phase-contrast MRI. Ann Biomed Eng (2009) 1.37
Chemical anoxia of tubular cells induces activation of c-Src and its translocation to the zonula adherens. Am J Physiol Renal Physiol (2002) 1.37
Genomic landscapes of Chinese hamster ovary cell lines as revealed by the Cricetulus griseus draft genome. Nat Biotechnol (2013) 1.36
Image quality optimization and evaluation of linearly mixed images in dual-source, dual-energy CT. Med Phys (2009) 1.36
lncRNA H19/miR-675 axis represses prostate cancer metastasis by targeting TGFBI. FEBS J (2014) 1.36
PTEN deletion in Bergmann glia leads to premature differentiation and affects laminar organization. Development (2005) 1.35
A genomic variation map provides insights into the genetic basis of cucumber domestication and diversity. Nat Genet (2013) 1.34
Gap junction remodeling and cardiac arrhythmogenesis in a murine model of oculodentodigital dysplasia. Proc Natl Acad Sci U S A (2007) 1.33
In-situ plasmon-driven chemical reactions revealed by high vacuum tip-enhanced Raman spectroscopy. Sci Rep (2012) 1.31
The common rs9939609 variant of the fat mass and obesity-associated gene is associated with obesity risk in children and adolescents of Beijing, China. BMC Med Genet (2010) 1.31
Time to tackle clonorchiasis in China. Infect Dis Poverty (2013) 1.31
NOD2 regulates hematopoietic cell function during graft-versus-host disease. J Exp Med (2009) 1.30
Transgenic expression of MYB15 confers enhanced sensitivity to abscisic acid and improved drought tolerance in Arabidopsis thaliana. J Genet Genomics (2009) 1.29
Genetically encoded cyclopropene directs rapid, photoclick-chemistry-mediated protein labeling in mammalian cells. Angew Chem Int Ed Engl (2012) 1.28
Metabolism of dietary soy isoflavones to equol by human intestinal microflora--implications for health. Mol Nutr Food Res (2007) 1.28
Broadening of neutralization activity to directly block a dominant antibody-driven SARS-coronavirus evolution pathway. PLoS Pathog (2008) 1.27
The beginning of the rpoB gene in addition to the rifampin resistance determination region might be needed for identifying rifampin/rifabutin cross-resistance in multidrug-resistant Mycobacterium tuberculosis isolates from Southern China. J Clin Microbiol (2011) 1.26
High pulsatility flow induces adhesion molecule and cytokine mRNA expression in distal pulmonary artery endothelial cells. Ann Biomed Eng (2009) 1.26
Manganese ferrite nanoparticle micellar nanocomposites as MRI contrast agent for liver imaging. Biomaterials (2009) 1.25