Published in Oncotarget on October 01, 2013
A novel approach to identify driver genes involved in androgen-independent prostate cancer. Mol Cancer (2014) 0.89
EphA6 promotes angiogenesis and prostate cancer metastasis and is associated with human prostate cancer progression. Oncotarget (2015) 0.84
Diet-induced hypercholesterolemia promotes androgen-independent prostate cancer metastasis via IQGAP1 and caveolin-1. Oncotarget (2015) 0.83
Galectin-3 Overrides PTRF/Cavin-1 Reduction of PC3 Prostate Cancer Cell Migration. PLoS One (2015) 0.82
Cavin-1/PTRF alters prostate cancer cell-derived extracellular vesicle content and internalization to attenuate extracellular vesicle-mediated osteoclastogenesis and osteoblast proliferation. J Extracell Vesicles (2014) 0.81
Integrative analysis identifies targetable CREB1/FoxA1 transcriptional co-regulation as a predictor of prostate cancer recurrence. Nucleic Acids Res (2016) 0.78
Cavin-1 and Caveolin-1 are both required to support cell proliferation, migration and anchorage-independent cell growth in rhabdomyosarcoma. Lab Invest (2015) 0.77
Anti-tumor activity of fenretinide complexed with human serum albumin in lung cancer xenograft mouse model. Oncotarget (2014) 0.76
PTRF suppresses the progression of colorectal cancers. Oncotarget (2017) 0.76
Non-caveolar caveolin-1 expression in prostate cancer cells promotes lymphangiogenesis. Oncoscience (2015) 0.75
Proteomics of thyroid tumours provides new insights into their molecular composition and changes associated with malignancy. Sci Rep (2016) 0.75
MiR-217 promotes cutaneous squamous cell carcinoma progression by targeting PTRF. Am J Transl Res (2017) 0.75
PTRF-Cavin, a conserved cytoplasmic protein required for caveola formation and function. Cell (2008) 4.42
Vascular endothelial growth factor expression of intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), and E-selectin through nuclear factor-kappa B activation in endothelial cells. J Biol Chem (2000) 3.45
Cytokine production and inflammation drive autophagy in the tumor microenvironment: role of stromal caveolin-1 as a key regulator. Cell Cycle (2011) 2.68
Molecular profiling of a lethal tumor microenvironment, as defined by stromal caveolin-1 status in breast cancers. Cell Cycle (2011) 2.67
The endothelial cell tube formation assay on basement membrane turns 20: state of the science and the art. Angiogenesis (2009) 2.67
Stromal cell expression of caveolin-1 predicts outcome in breast cancer. Am J Pathol (2009) 2.44
Deletion of Cavin/PTRF causes global loss of caveolae, dyslipidemia, and glucose intolerance. Cell Metab (2008) 2.28
A critical role of cavin (polymerase I and transcript release factor) in caveolae formation and organization. J Biol Chem (2007) 1.96
Vascular endothelial growth factor-C expression in human prostatic carcinoma and its relationship to lymph node metastasis. Br J Cancer (1999) 1.87
Angiogenesis and prostate cancer: in vivo and in vitro expression of angiogenesis factors by prostate cancer cells. Urology (1998) 1.73
Secreted caveolin-1 stimulates cell survival/clonal growth and contributes to metastasis in androgen-insensitive prostate cancer. Cancer Res (2001) 1.66
Expression of vascular endothelial growth factor C (VEGF-C) and VEGF receptor-3 in human prostate cancer is associated with regional lymph node metastasis. Prostate (2005) 1.56
Microvessel density predicts survival in prostate cancer patients subjected to watchful waiting. Br J Cancer (1998) 1.38
Tumor cell-secreted caveolin-1 has proangiogenic activities in prostate cancer. Cancer Res (2008) 1.37
The biology of caveolae: achievements and perspectives. Int Rev Cell Mol Biol (2009) 1.28
Deletion of cavin genes reveals tissue-specific mechanisms for morphogenesis of endothelial caveolae. Nat Commun (2013) 1.24
Interactions of vascular wall cells with collagen gels. Lab Invest (1982) 1.20
Tumor-induced activation of lymphatic endothelial cells via vascular endothelial growth factor receptor-2 is critical for prostate cancer lymphatic metastasis. Cancer Res (2006) 1.17
Identification and validation of differences in protein levels in normal, premalignant, and malignant lung cells and tissues using high-throughput Western Array and immunohistochemistry. Cancer Res (2006) 1.17
Preoperative serum caveolin-1 as a prognostic marker for recurrence in a radical prostatectomy cohort. Clin Cancer Res (2006) 1.16
Expression of vascular endothelial growth factor receptor-3 by lymphatic endothelial cells is associated with lymph node metastasis in prostate cancer. Clin Cancer Res (2004) 1.13
Microvessel density in prostate carcinoma. Prostate Cancer Prostatic Dis (2002) 1.11
PTRF-cavin-1 expression decreases the migration of PC3 prostate cancer cells: role of matrix metalloprotease 9. Eur J Cell Biol (2010) 1.07
Loss of stromal caveolin-1 expression in malignant melanoma metastases predicts poor survival. Cell Cycle (2011) 1.07
Phosphocaveolin-1 is a mechanotransducer that induces caveola biogenesis via Egr1 transcriptional regulation. J Cell Biol (2012) 1.03
Lymphatic vessel density and lymph node metastasis in prostate cancer. Prostate (2005) 1.03
Molecular mechanisms of replicative senescence in endothelial cells. Exp Gerontol (2003) 1.01
Membrane lipids in invadopodia and podosomes: key structures for cancer invasion and metastasis. Oncotarget (2010) 1.00
Down-regulation of the cavin family proteins in breast cancer. J Cell Biochem (2012) 0.99
Functional analysis of secreted caveolin-1 in mouse models of prostate cancer progression. Mol Cancer Res (2009) 0.99
Correlation of vascular endothelial growth factor expression with fibroblast growth factor-8 expression and clinico-pathologic parameters in human prostate cancer. Br J Cancer (2001) 0.99
Changes in caveolae, caveolin, and polymerase 1 and transcript release factor (PTRF) expression in prostate cancer progression. Prostate (2010) 0.97
Expression of PTRF in PC-3 Cells modulates cholesterol dynamics and the actin cytoskeleton impacting secretion pathways. Mol Cell Proteomics (2011) 0.95
Co-regulation of cell polarization and migration by caveolar proteins PTRF/Cavin-1 and caveolin-1. PLoS One (2012) 0.94
Clinical importance of lymph node density in predicting outcome of prostate cancer patients. J Surg Res (2009) 0.94
Cavin-1 is essential for the tumor-promoting effect of caveolin-1 and enhances its prognostic potency in pancreatic cancer. Oncogene (2013) 0.92
PTRF/cavin-1 and MIF proteins are identified as non-small cell lung cancer biomarkers by label-free proteomics. PLoS One (2012) 0.91
Caveolin-1 in sarcomas: friend or foe? Oncotarget (2011) 0.90
Caveolin-1 polarization in transmigrating endothelial cells requires binding to intermediate filaments. Angiogenesis (2007) 0.89
Targeting receptor tyrosine kinase on lymphatic endothelial cells for the therapy of colon cancer lymph node metastasis. Neoplasia (2006) 0.88
Caveolin-1 promotes pancreatic cancer cell differentiation and restores membranous E-cadherin via suppression of the epithelial-mesenchymal transition. Cell Cycle (2011) 0.87
PTRF/cavin-1 neutralizes non-caveolar caveolin-1 microdomains in prostate cancer. Oncogene (2013) 0.86
A system for quantifying the patterning of the lymphatic vasculature. Growth Factors (2007) 0.86
Caveola-forming proteins caveolin-1 and PTRF in prostate cancer. Nat Rev Urol (2013) 0.86
Altered angiogenesis in caveolin-1 gene-deficient mice is restored by ablation of endothelial nitric oxide synthase. Am J Pathol (2012) 0.85
Caveolin-1: would-be Achilles' heel of tumor microenvironment? Cell Cycle (2011) 0.81
Mango extracts and the mango component mangiferin promote endothelial cell migration. J Agric Food Chem (2010) 0.80
Laparoscopic pelvic lymph node dissection in the staging of prostate cancer. Mt Sinai J Med (1999) 0.79
Angiogenic factors expressed by human prostatic cell lines: effect on endothelial cell growth in vitro. Prostate (1997) 0.79
Lipid droplets: a unified view of a dynamic organelle. Nat Rev Mol Cell Biol (2006) 6.85
Direct visualization of Ras proteins in spatially distinct cell surface microdomains. J Cell Biol (2003) 5.45
PTRF-Cavin, a conserved cytoplasmic protein required for caveola formation and function. Cell (2008) 4.42
Role of LBPA and Alix in multivesicular liposome formation and endosome organization. Science (2004) 4.35
GPI-anchored proteins are delivered to recycling endosomes via a distinct cdc42-regulated, clathrin-independent pinocytic pathway. Dev Cell (2002) 4.28
APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartment. Cell (2004) 3.95
Plasma membrane nanoswitches generate high-fidelity Ras signal transduction. Nat Cell Biol (2007) 3.90
H-ras, K-ras, and inner plasma membrane raft proteins operate in nanoclusters with differential dependence on the actin cytoskeleton. Proc Natl Acad Sci U S A (2005) 3.78
Cells respond to mechanical stress by rapid disassembly of caveolae. Cell (2011) 3.55
Endosome-to-cytosol transport of viral nucleocapsids. Nat Cell Biol (2005) 2.98
Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast. J Cell Biol (2008) 2.85
Caveolin-1 is essential for liver regeneration. Science (2006) 2.77
Ultrastructural identification of uncoated caveolin-independent early endocytic vehicles. J Cell Biol (2005) 2.74
Sequence-dependent sorting of recycling proteins by actin-stabilized endosomal microdomains. Cell (2010) 2.67
The Rab5 effector Rabankyrin-5 regulates and coordinates different endocytic mechanisms. PLoS Biol (2004) 2.59
Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens. Nat Cell Biol (2010) 2.51
Membrane insertion of anthrax protective antigen and cytoplasmic delivery of lethal factor occur at different stages of the endocytic pathway. J Cell Biol (2004) 2.31
Individual palmitoyl residues serve distinct roles in H-ras trafficking, microlocalization, and signaling. Mol Cell Biol (2005) 2.24
Regulated localization of Rab18 to lipid droplets: effects of lipolytic stimulation and inhibition of lipid droplet catabolism. J Biol Chem (2005) 2.15
Differential sorting and fate of endocytosed GPI-anchored proteins. EMBO J (2002) 2.15
Ras plasma membrane signalling platforms. Biochem J (2005) 2.15
Cholesterol manipulation by West Nile virus perturbs the cellular immune response. Cell Host Microbe (2007) 2.14
Three separable domains regulate GTP-dependent association of H-ras with the plasma membrane. Mol Cell Biol (2004) 2.09
Not just fat: the structure and function of the lipid droplet. Cold Spring Harb Perspect Biol (2011) 2.07
A novel switch region regulates H-ras membrane orientation and signal output. EMBO J (2008) 2.06
Characterization of E-cadherin endocytosis in isolated MCF-7 and chinese hamster ovary cells: the initial fate of unbound E-cadherin. J Biol Chem (2003) 2.05
Flotillins and the PHB domain protein family: rafts, worms and anaesthetics. Traffic (2005) 2.01
Rab23, a negative regulator of hedgehog signaling, localizes to the plasma membrane and the endocytic pathway. Traffic (2003) 1.88
Association of stomatin with lipid bodies. J Biol Chem (2004) 1.88
MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes. J Cell Biol (2009) 1.87
Clathrin-independent endocytosis: new insights into caveolae and non-caveolar lipid raft carriers. Biochim Biophys Acta (2005) 1.87
Selective stimulation of caveolar endocytosis by glycosphingolipids and cholesterol. Mol Biol Cell (2004) 1.86
Cholesterol and fatty acids regulate dynamic caveolin trafficking through the Golgi complex and between the cell surface and lipid bodies. Mol Biol Cell (2005) 1.86
Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies. PLoS Biol (2008) 1.85
Annexin II regulates multivesicular endosome biogenesis in the degradation pathway of animal cells. EMBO J (2003) 1.85
N4WBP5, a potential target for ubiquitination by the Nedd4 family of proteins, is a novel Golgi-associated protein. J Biol Chem (2001) 1.84
Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells. J Cell Biol (2010) 1.84
Fsp27 promotes lipid droplet growth by lipid exchange and transfer at lipid droplet contact sites. J Cell Biol (2011) 1.84
Clathrin-independent endocytosis: new insights into caveolae and non-caveolar lipid raft carriers. Biochim Biophys Acta (2005) 1.83
Identifying optimal lipid raft characteristics required to promote nanoscale protein-protein interactions on the plasma membrane. Mol Cell Biol (2006) 1.81
Lipid droplet-organelle interactions; sharing the fats. Biochim Biophys Acta (2008) 1.77
Molecules, mechanisms, and cellular roles of clathrin-independent endocytosis. Curr Opin Cell Biol (2010) 1.70
A role for phosphatidic acid in the formation of "supersized" lipid droplets. PLoS Genet (2011) 1.69
Dynamic microtubules regulate the local concentration of E-cadherin at cell-cell contacts. J Cell Sci (2006) 1.68
Annexin A2-dependent polymerization of actin mediates endosome biogenesis. Dev Cell (2009) 1.67
Cell-to-cell heterogeneity in lipid droplets suggests a mechanism to reduce lipotoxicity. Curr Biol (2013) 1.66
Lysobisphosphatidic acid controls endosomal cholesterol levels. J Biol Chem (2008) 1.62
The GTPase-activating protein GRAF1 regulates the CLIC/GEEC endocytic pathway. Curr Biol (2008) 1.62
Dynamic and regulated association of caveolin with lipid bodies: modulation of lipid body motility and function by a dominant negative mutant. Mol Biol Cell (2003) 1.62
Cholesterol-sensitive Cdc42 activation regulates actin polymerization for endocytosis via the GEEC pathway. Traffic (2007) 1.55
Inhibitors of COP-mediated transport and cholera toxin action inhibit simian virus 40 infection. Mol Biol Cell (2002) 1.53
Flotillin-1/reggie-2 traffics to surface raft domains via a novel golgi-independent pathway. Identification of a novel membrane targeting domain and a role for palmitoylation. J Biol Chem (2002) 1.51
Glucose principally regulates insulin secretion in mouse islets by controlling the numbers of granule fusion events per cell. Diabetologia (2013) 1.51
Late endosomal cholesterol accumulation leads to impaired intra-endosomal trafficking. PLoS One (2007) 1.50
High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine. J Cell Biol (2011) 1.49
A role for oxysterol-binding protein-related protein 5 in endosomal cholesterol trafficking. J Cell Biol (2011) 1.48
A single method for cryofixation and correlative light, electron microscopy and tomography of zebrafish embryos. Traffic (2008) 1.48
Cholesterol-induced caveolin targeting to lipid droplets in adipocytes: a role for caveolar endocytosis. Traffic (2006) 1.48
Review: biogenesis of the multifunctional lipid droplet: lipids, proteins, and sites. J Cell Biol (2014) 1.45
Role of intratumoural heterogeneity in cancer drug resistance: molecular and clinical perspectives. EMBO Mol Med (2012) 1.41
Caveolin, cholesterol, and lipid bodies. Semin Cell Dev Biol (2005) 1.41
Abrogation of PIK3CA or PIK3R1 reduces proliferation, migration, and invasion in glioblastoma multiforme cells. Oncotarget (2011) 1.39
A role for caveolae in cell migration. FASEB J (2004) 1.38
Caveolin regulates endocytosis of the muscle repair protein, dysferlin. J Biol Chem (2007) 1.37
Electrostatic interactions positively regulate K-Ras nanocluster formation and function. Mol Cell Biol (2008) 1.34
Zebrafish as a model for caveolin-associated muscle disease; caveolin-3 is required for myofibril organization and muscle cell patterning. Hum Mol Genet (2005) 1.34
High-resolution 3D quantitative analysis of caveolar ultrastructure and caveola-cytoskeleton interactions. Traffic (2008) 1.32
Observing cell surface signaling domains using electron microscopy. Sci STKE (2003) 1.32
Caveolae at a glance. J Cell Sci (2010) 1.31
Pore-forming toxins induce multiple cellular responses promoting survival. Cell Microbiol (2011) 1.28
A novel hook-related protein family and the characterization of hook-related protein 1. Traffic (2005) 1.27
Activation of the MAPK module from different spatial locations generates distinct system outputs. Mol Biol Cell (2008) 1.25
Evolutionary analysis and molecular dissection of caveola biogenesis. J Cell Sci (2008) 1.25
Epidermal growth factor receptor activation remodels the plasma membrane lipid environment to induce nanocluster formation. Mol Cell Biol (2010) 1.25
Visualisation of macropinosome maturation by the recruitment of sorting nexins. J Cell Sci (2006) 1.25
Expression of caveolin-1 enhances cholesterol efflux in hepatic cells. J Biol Chem (2004) 1.24
The Schlemm's canal is a VEGF-C/VEGFR-3-responsive lymphatic-like vessel. J Clin Invest (2014) 1.23
Caveolin interacts with the angiotensin II type 1 receptor during exocytic transport but not at the plasma membrane. J Biol Chem (2003) 1.22
Hydrophobic and basic domains target proteins to lipid droplets. Traffic (2009) 1.22
Arf6-independent GPI-anchored protein-enriched early endosomal compartments fuse with sorting endosomes via a Rab5/phosphatidylinositol-3'-kinase-dependent machinery. Mol Biol Cell (2006) 1.21
The endocytic protein GRAF1 is directed to cell-matrix adhesion sites and regulates cell spreading. Mol Biol Cell (2011) 1.20
Quantitative analysis of lipid droplet fusion: inefficient steady state fusion but rapid stimulation by chemical fusogens. PLoS One (2010) 1.19
Mutant huntingtin inhibits clathrin-independent endocytosis and causes accumulation of cholesterol in vitro and in vivo. Hum Mol Genet (2006) 1.19
Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission. J Biol Chem (2013) 1.19
EHD2 regulates caveolar dynamics via ATP-driven targeting and oligomerization. Mol Biol Cell (2012) 1.18
Morphine and tumor growth and metastasis. Cancer Metastasis Rev (2011) 1.17
RORalpha regulates the expression of genes involved in lipid homeostasis in skeletal muscle cells: caveolin-3 and CPT-1 are direct targets of ROR. J Biol Chem (2004) 1.17
Staurosporines disrupt phosphatidylserine trafficking and mislocalize Ras proteins. J Biol Chem (2012) 1.15
Building a better dynasore: the dyngo compounds potently inhibit dynamin and endocytosis. Traffic (2013) 1.14
Aberrant dysferlin trafficking in cells lacking caveolin or expressing dystrophy mutants of caveolin-3. Hum Mol Genet (2005) 1.14
Characterization of Rab18, a lipid droplet-associated small GTPase. Methods Enzymol (2008) 1.14
Human Miltons associate with mitochondria and induce microtubule-dependent remodeling of mitochondrial networks. Biochim Biophys Acta (2010) 1.14
Acyl-CoA synthetase 3 promotes lipid droplet biogenesis in ER microdomains. J Cell Biol (2013) 1.11
Caveolae regulate the nanoscale organization of the plasma membrane to remotely control Ras signaling. J Cell Biol (2014) 1.10