A novel Hsp90 inhibitor AT13387 induces senescence in EBV-positive nasopharyngeal carcinoma cells and suppresses tumor formation.

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Published in Mol Cancer on October 24, 2013

Authors

King Chi Chan, Choi Man Ting, Pui Shan Chan, Ming Chu Lo, Kwok Wai Lo, Jayne E Curry, Tomoko Smyth, Anne Wing Mui Lee, Wai Tong Ng, George Sai Wah Tsao, Ricky Ngok Shun Wong, Maria Li Lung, Nai Ki Mak1

Author Affiliations

1: Department of Biology, Hong Kong Baptist University, Hong Kong, P,R, China. nkmak@hkbu.edu.hk.

Associated clinical trials:

A Study of AT13387 in Patients With Non-Small Cell Lung Cancer (NSCLC) Alone and in Combination With Crizotinib | NCT01712217

A Study of HSP90 Inhibitor AT13387 Alone or in Combination With Abiraterone Acetate | NCT01685268

A Study to Investigate the Safety and Efficacy of AT13387, Alone or in Combination With Imatinib, in Patients With GIST | NCT01294202

Study to Assess the Safety of Escalating Doses of AT13387 in Patients With Metastatic Solid Tumors | NCT00878423

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