Published in Exp Neurol on November 04, 2013
G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination. Nat Commun (2016) 0.83
Extracellular matrix composition determines astrocyte responses to mechanical and inflammatory stimuli. Neurosci Lett (2015) 0.80
Remyelination Therapy in Multiple Sclerosis. Front Neurol (2015) 0.79
Chondroitin sulfate proteoglycans in the nervous system: inhibitors to repair. Biomed Res Int (2014) 0.79
A Sativex(®) -like combination of phytocannabinoids as a disease-modifying therapy in a viral model of multiple sclerosis. Br J Pharmacol (2015) 0.77
Biomaterial Approaches to Enhancing Neurorestoration after Spinal Cord Injury: Strategies for Overcoming Inherent Biological Obstacles. Biomed Res Int (2015) 0.77
Zebrafish as a model to investigate CNS myelination. Glia (2014) 0.77
Extracellular cues influencing oligodendrocyte differentiation and (re)myelination. Exp Neurol (2016) 0.76
Mechanical Strain Promotes Oligodendrocyte Differentiation by Global Changes of Gene Expression. Front Cell Neurosci (2017) 0.75
Delayed ALK5 inhibition improves functional recovery in neonatal brain injury. J Cereb Blood Flow Metab (2016) 0.75
Nogo receptor blockade overcomes remyelination failure after white matter stroke and stimulates functional recovery in aged mice. Proc Natl Acad Sci U S A (2016) 0.75
The environment rules: spatiotemporal regulation of oligodendrocyte differentiation. Curr Opin Neurobiol (2016) 0.75
Regeneration beyond the glial scar. Nat Rev Neurosci (2004) 11.00
Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis. Nat Med (2002) 8.33
Chondroitinase ABC promotes functional recovery after spinal cord injury. Nature (2002) 8.22
Glial inhibition of CNS axon regeneration. Nat Rev Neurosci (2006) 6.91
Reactive astrocytes protect tissue and preserve function after spinal cord injury. J Neurosci (2004) 5.70
CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure. Exp Neurol (2007) 4.00
NG2 proteoglycan is expressed exclusively by mural cells during vascular morphogenesis. Dev Dyn (2001) 3.71
Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis. N Engl J Med (2002) 3.68
Why does remyelination fail in multiple sclerosis? Nat Rev Neurosci (2002) 3.28
NG2-positive oligodendrocyte progenitor cells in adult human brain and multiple sclerosis lesions. J Neurosci (2000) 2.87
PTPsigma is a receptor for chondroitin sulfate proteoglycan, an inhibitor of neural regeneration. Science (2009) 2.84
The role of extracellular matrix in CNS regeneration. Curr Opin Neurobiol (2007) 2.77
Distinct stages of myelination regulated by gamma-secretase and astrocytes in a rapidly myelinating CNS coculture system. Neuron (2008) 2.74
Robust regeneration of adult sensory axons in degenerating white matter of the adult rat spinal cord. J Neurosci (1999) 2.64
Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination. Nat Neurosci (2011) 2.61
Progenitor cells of the adult mouse subventricular zone proliferate, migrate and differentiate into oligodendrocytes after demyelination. Eur J Neurosci (1999) 2.56
Hyaluronan accumulates in demyelinated lesions and inhibits oligodendrocyte progenitor maturation. Nat Med (2005) 2.46
Lecticans: organizers of the brain extracellular matrix. Cell Mol Life Sci (2000) 2.45
The role of chondroitin sulfate proteoglycans in regeneration and plasticity in the central nervous system. Brain Res Rev (2007) 2.42
Sulfation patterns of glycosaminoglycans encode molecular recognition and activity. Nat Chem Biol (2006) 2.25
Chondroitin sulfate proteoglycans in demyelinated lesions impair remyelination. Ann Neurol (2012) 2.25
Extracellular regulators of axonal growth in the adult central nervous system. Philos Trans R Soc Lond B Biol Sci (2006) 2.10
Growth-associated gene expression after stroke: evidence for a growth-promoting region in peri-infarct cortex. Exp Neurol (2005) 2.08
Regulation of growth factor activation by proteoglycans: what is the role of the low affinity receptors? Cell (1995) 2.06
Changes in distribution, cell associations, and protein expression levels of NG2, neurocan, phosphacan, brevican, versican V2, and tenascin-C during acute to chronic maturation of spinal cord scar tissue. J Neurosci Res (2003) 2.04
NG2 is a major chondroitin sulfate proteoglycan produced after spinal cord injury and is expressed by macrophages and oligodendrocyte progenitors. J Neurosci (2002) 2.03
Proliferation of NG2-positive cells and altered oligodendrocyte numbers in the contused rat spinal cord. J Neurosci (2001) 2.03
Inhibiting glycosaminoglycan chain polymerization decreases the inhibitory activity of astrocyte-derived chondroitin sulfate proteoglycans. J Neurosci (2007) 1.99
Chondroitinase ABC promotes sprouting of intact and injured spinal systems after spinal cord injury. J Neurosci (2006) 1.99
NG2 glial cells provide a favorable substrate for growing axons. J Neurosci (2006) 1.99
Extracellular matrix molecules that influence neural development. Annu Rev Neurosci (1989) 1.97
NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans. Nat Neurosci (2012) 1.94
Pro-regenerative properties of cytokine-activated astrocytes. J Neurochem (2004) 1.83
Proteoglycans in the developing brain: new conceptual insights for old proteins. Physiol Rev (2000) 1.81
Negative regulation of EGFR signalling through integrin-alpha1beta1-mediated activation of protein tyrosine phosphatase TCPTP. Nat Cell Biol (2004) 1.81
Proteoglycans: from structural compounds to signaling molecules. Cell Tissue Res (2009) 1.80
Myelin-, reactive glia-, and scar-derived CNS axon growth inhibitors: expression, receptor signaling, and correlation with axon regeneration. Glia (2004) 1.79
Macrophage depletion impairs oligodendrocyte remyelination following lysolecithin-induced demyelination. Glia (2001) 1.71
Chondroitin sulphate proteoglycans in the CNS injury response. Prog Brain Res (2002) 1.70
Laminin forms an independent network in basement membranes. J Cell Biol (1992) 1.68
The presence of heparan sulfate proteoglycans in the neuritic plaques and congophilic angiopathy in Alzheimer's disease. Am J Pathol (1988) 1.65
Collagens. Cell Tissue Res (2009) 1.62
Extracellular matrix in multiple sclerosis lesions: Fibrillar collagens, biglycan and decorin are upregulated and associated with infiltrating immune cells. Brain Pathol (2010) 1.61
Proteoglycan-specific molecular switch for RPTPσ clustering and neuronal extension. Science (2011) 1.59
Knockout mice reveal a contribution of the extracellular matrix molecule tenascin-C to neural precursor proliferation and migration. Development (2001) 1.54
Astrocytes--friends or foes in multiple sclerosis? Glia (2007) 1.52
Axonal regeneration through regions of chondroitin sulfate proteoglycan deposition after spinal cord injury: a balance of permissiveness and inhibition. J Neurosci (2003) 1.52
Leukocyte common antigen-related phosphatase is a functional receptor for chondroitin sulfate proteoglycan axon growth inhibitors. J Neurosci (2011) 1.52
Hyaluronan blocks oligodendrocyte progenitor maturation and remyelination through TLR2. Proc Natl Acad Sci U S A (2010) 1.51
NG2+ glial cells: a novel glial cell population in the adult brain. J Neuropathol Exp Neurol (1999) 1.49
Extracellular matrix of the central nervous system: from neglect to challenge. Histochem Cell Biol (2008) 1.48
Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination. Ann Neurol (2010) 1.47
Laminin-2/integrin interactions enhance myelin membrane formation by oligodendrocytes. Mol Cell Neurosci (1999) 1.43
Heparan sulfate proteoglycans are ligands for receptor protein tyrosine phosphatase sigma. Mol Cell Biol (2002) 1.43
Nerve fiber growth in culture on fibronectin, collagen, and glycosaminoglycan substrates. J Neurosci (1983) 1.41
Endogenous Nkx2.2+/Olig2+ oligodendrocyte precursor cells fail to remyelinate the demyelinated adult rat spinal cord in the absence of astrocytes. Exp Neurol (2005) 1.41
The relevance of animal models in multiple sclerosis research. Pathophysiology (2011) 1.40
Glial cell extracellular matrix: boundaries for axon growth in development and regeneration. Cell Tissue Res (1997) 1.39
Chondroitin sulphate proteoglycans: preventing plasticity or protecting the CNS? J Anat (2004) 1.39
Corticospinal tract regeneration after spinal cord injury in receptor protein tyrosine phosphatase sigma deficient mice. Glia (2010) 1.36
Increased chondroitin sulfate proteoglycan expression in denervated brainstem targets following spinal cord injury creates a barrier to axonal regeneration overcome by chondroitinase ABC and neurotrophin-3. Exp Neurol (2007) 1.35
Decorin suppresses neurocan, brevican, phosphacan and NG2 expression and promotes axon growth across adult rat spinal cord injuries. Eur J Neurosci (2004) 1.32
The extracellular matrix of the central and peripheral nervous systems: structure and function. J Neurosurg (1988) 1.32
Identification of a cell-surface protein involved in PC12 cell-substratum adhesion and neurite outgrowth on laminin and collagen. J Neurosci (1989) 1.31
Prominent oligodendrocyte genesis along the border of spinal contusion lesions. Glia (2007) 1.29
Laminin is induced in astrocytes of adult brain by injury. EMBO J (1984) 1.28
Phosphacan, a chondroitin sulfate proteoglycan of brain that interacts with neurons and neural cell-adhesion molecules, is an extracellular variant of a receptor-type protein tyrosine phosphatase. Proc Natl Acad Sci U S A (1994) 1.25
Manipulating the glial scar: chondroitinase ABC as a therapy for spinal cord injury. Brain Res Bull (2010) 1.25
A role in migration for the alpha V beta 1 integrin expressed on oligodendrocyte precursors. J Neurosci (1996) 1.25
Fibronectin and glial fibrillary acidic protein expression in normal human brain and anaplastic human gliomas. Cancer Res (1982) 1.25
A critical role for the protein tyrosine phosphatase receptor type Z in functional recovery from demyelinating lesions. Nat Genet (2002) 1.24
J1-160 and J1-180 are oligodendrocyte-secreted nonpermissive substrates for cell adhesion. J Cell Biol (1989) 1.24
Chondroitinase ABC improves basic and skilled locomotion in spinal cord injured cats. Exp Neurol (2007) 1.22
Brain derived versican V2 is a potent inhibitor of axonal growth. J Cell Sci (2000) 1.20
How does chondroitinase promote functional recovery in the damaged CNS? Exp Neurol (2007) 1.20
Multiple sclerosis: remyelination in acute lesions. J Neuropathol Exp Neurol (1993) 1.20
Antibodies against the NG2 proteoglycan promote the regeneration of sensory axons within the dorsal columns of the spinal cord. J Neurosci (2006) 1.20
Distribution and synthesis of extracellular matrix proteoglycans, hyaluronan, link proteins and tenascin-R in the rat spinal cord. Eur J Neurosci (2008) 1.19
NG2 colocalizes with axons and is expressed by a mixed cell population in spinal cord lesions. J Neuropathol Exp Neurol (2006) 1.19
Chondroitin sulfate proteoglycan immunoreactivity increases following spinal cord injury and transplantation. Exp Neurol (1999) 1.18
Chondroitin sulfate: a key molecule in the brain matrix. Int J Biochem Cell Biol (2012) 1.18
Early accumulation of heparan sulfate in neurons and in the beta-amyloid protein-containing lesions of Alzheimer's disease and Down's syndrome. Am J Pathol (1990) 1.17
A 'GAG' reflex prevents repair of the damaged CNS. Trends Neurosci (2007) 1.17
Oligodendrocyte generation is differentially influenced by toll-like receptor (TLR) 2 and TLR4-mediated intraspinal macrophage activation. J Neuropathol Exp Neurol (2007) 1.15
Scar-mediated inhibition and CSPG receptors in the CNS. Exp Neurol (2012) 1.14
Structural basis for interactions between tenascins and lectican C-type lectin domains: evidence for a crosslinking role for tenascins. Structure (2004) 1.14
The injury response of oligodendrocyte precursor cells is induced by platelets, macrophages and inflammation-associated cytokines. Neuroscience (2006) 1.13
NG2: a component of the glial scar that inhibits axon growth. J Anat (2005) 1.11
Versican V2 is a major extracellular matrix component of the mature bovine brain. J Biol Chem (1998) 1.11
Chondroitinase ABC promotes compensatory sprouting of the intact corticospinal tract and recovery of forelimb function following unilateral pyramidotomy in adult mice. Eur J Neurosci (2012) 1.09
A complex between contactin-1 and the protein tyrosine phosphatase PTPRZ controls the development of oligodendrocyte precursor cells. Proc Natl Acad Sci U S A (2011) 1.09
Protein tyrosine phosphatase alpha (PTPalpha): a Src family kinase activator and mediator of multiple biological effects. Curr Top Med Chem (2003) 1.09
Sulfate content and specific glycosaminoglycan backbone of perlecan are critical for perlecan's enhancement of islet amyloid polypeptide (amylin) fibril formation. Diabetes (1998) 1.09
Fibronectin in multiple sclerosis lesions. Am J Pathol (1989) 1.08
Analysis of axonal regeneration in the central and peripheral nervous systems of the NG2-deficient mouse. BMC Neurosci (2007) 1.07
Astrogliosis in EAE spinal cord: derivation from radial glia, and relationships to oligodendroglia. Glia (2007) 1.06
Promoting oligodendrogenesis and myelin repair using the multiple sclerosis medication glatiramer acetate. Proc Natl Acad Sci U S A (2009) 1.02
Extensive extracellular matrix depositions in active multiple sclerosis lesions. Neurobiol Dis (2006) 1.02
Pathogenic and regulatory roles for B cells in experimental autoimmune encephalomyelitis. Autoimmunity (2012) 1.02
DSD-1-proteoglycan is the mouse homolog of phosphacan and displays opposing effects on neurite outgrowth dependent on neuronal lineage. J Neurosci (1999) 1.02