PubRank

Bruce Chesebro

Author PubWeight™ 46.49‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Getting a grip on prions: oligomers, amyloids, and pathological membrane interactions. Annu Rev Biochem 2009 2.80
2 Conversion of raft associated prion protein to the protease-resistant state requires insertion of PrP-res (PrP(Sc)) into contiguous membranes. EMBO J 2002 2.16
3 Apobec3 encodes Rfv3, a gene influencing neutralizing antibody control of retrovirus infection. Science 2008 1.97
4 Biomedicine. A view from the top--prion diseases from 10,000 feet. Science 2003 1.48
5 Resistance to chronic wasting disease in transgenic mice expressing a naturally occurring allelic variant of deer prion protein. J Virol 2007 1.41
6 Mice devoid of prion protein have cognitive deficits that are rescued by reconstitution of PrP in neurons. Neurobiol Dis 2005 1.39
7 Role of low CD4 levels in the influence of human immunodeficiency virus type 1 envelope V1 and V2 regions on entry and spread in macrophages. J Virol 2005 1.34
8 Susceptibilities of nonhuman primates to chronic wasting disease. Emerg Infect Dis 2009 1.33
9 Subclinical scrapie infection in a resistant species: persistence, replication, and adaptation of infectivity during four passages. J Infect Dis 2002 1.28
10 Gene expression alterations in brains of mice infected with three strains of scrapie. BMC Genomics 2006 1.27
11 Lower specific infectivity of protease-resistant prion protein generated in cell-free reactions. Proc Natl Acad Sci U S A 2011 1.26
12 Scrapie-specific neuronal lesions are independent of neuronal PrP expression. Ann Neurol 2004 1.24
13 Prion-induced amyloid heart disease with high blood infectivity in transgenic mice. Science 2006 1.23
14 MCP-1 and CCR2 contribute to non-lymphocyte-mediated brain disease induced by Fr98 polytropic retrovirus infection in mice: role for astrocytes in retroviral neuropathogenesis. J Virol 2004 1.17
15 Lymphotoxin-alpha- and lymphotoxin-beta-deficient mice differ in susceptibility to scrapie: evidence against dendritic cell involvement in neuroinvasion. J Virol 2002 1.13
16 Detection of prion infectivity in fat tissues of scrapie-infected mice. PLoS Pathog 2008 1.08
17 Differences in scrapie-induced pathology of the retina and brain in transgenic mice that express hamster prion protein in neurons, astrocytes, or multiple cell types. Am J Pathol 2004 1.07
18 Crucial role for prion protein membrane anchoring in the neuroinvasion and neural spread of prion infection. J Virol 2010 1.06
19 Analysis of protein levels of 24 cytokines in scrapie agent-infected brain and glial cell cultures from mice differing in prion protein expression levels. J Virol 2009 1.03
20 Flexible N-terminal region of prion protein influences conformation of protease-resistant prion protein isoforms associated with cross-species scrapie infection in vivo and in vitro. J Biol Chem 2004 1.01
21 Role of cyclophilin A from brains of prion-infected mice in stimulation of cytokine release by microglia and astroglia in vitro. J Biol Chem 2011 0.95
22 Novel role of CD8(+) T cells and major histocompatibility complex class I genes in the generation of protective CD4(+) Th1 responses during retrovirus infection in mice. J Virol 2002 0.93
23 Levels of abnormal prion protein in deer and elk with chronic wasting disease. Emerg Infect Dis 2007 0.93
24 Prion protein and susceptibility to kainate-induced seizures: genetic pitfalls in the use of PrP knockout mice. Prion 2013 0.91
25 Role of Erk1/2 activation in prion disease pathogenesis: absence of CCR1 leads to increased Erk1/2 activation and accelerated disease progression. J Neuroimmunol 2008 0.91
26 Prion infectivity in fat of deer with chronic wasting disease. J Virol 2009 0.91
27 Human immunodeficiency virus type 1 envelope-mediated neuronal death: uncoupling of viral replication and neurotoxicity. J Virol 2003 0.91
28 Early cytokine elevation, PrPres deposition, and gliosis in mouse scrapie: no effect on disease by deletion of cytokine genes IL-12p40 and IL-12p35. J Virol 2012 0.90
29 Prion protein expression differences in microglia and astroglia influence scrapie-induced neurodegeneration in the retina and brain of transgenic mice. J Virol 2007 0.90
30 Separate sequences in a murine retroviral envelope protein mediate neuropathogenesis by complementary mechanisms with differing requirements for tumor necrosis factor alpha. J Virol 2004 0.89
31 Functional characteristics of HIV-1 subtype C compatible with increased heterosexual transmissibility. AIDS 2009 0.88
32 In vivo comparison of chronic wasting disease infectivity from deer with variation at prion protein residue 96. J Virol 2011 0.88
33 Strain specific resistance to murine scrapie associated with a naturally occurring human prion protein polymorphism at residue 171. PLoS Pathog 2011 0.88
34 Unusual cerebral vascular prion protein amyloid distribution in scrapie-infected transgenic mice expressing anchorless prion protein. Acta Neuropathol Commun 2013 0.85
35 Increased proinflammatory cytokine and chemokine responses and microglial infection following inoculation with neural stem cells infected with polytropic murine retroviruses. Virology 2006 0.84
36 Prion disease induced alterations in gene expression in spleen and brain prior to clinical symptoms. Adv Appl Bioinform Chem 2008 0.83
37 Neurovirulence of polytropic murine retrovirus is influenced by two separate regions on opposite sides of the envelope protein receptor binding domain. J Virol 2008 0.82
38 Disinfection and sterilization of prion-contaminated medical instruments. Infect Control Hosp Epidemiol 2010 0.81
39 Increased excitatory amino acid transport into murine prion protein knockout astrocytes cultured in vitro. Glia 2011 0.79
40 Chronic wasting disease agents in nonhuman primates. Emerg Infect Dis 2014 0.79
41 Prion protein on astrocytes or in extracellular fluid impedes neurodegeneration induced by truncated prion protein. Exp Neurol 2009 0.78
42 Proteomics analysis of amyloid and nonamyloid prion disease phenotypes reveals both common and divergent mechanisms of neuropathogenesis. J Proteome Res 2014 0.77