Published in Mol Cell on November 21, 2013
Long noncoding RNAs in cell-fate programming and reprogramming. Cell Stem Cell (2014) 1.47
X chromosome regulation: diverse patterns in development, tissues and disease. Nat Rev Genet (2014) 1.36
Xist localization and function: new insights from multiple levels. Genome Biol (2015) 0.90
X chromosome reactivation dynamics reveal stages of reprogramming to pluripotency. Cell (2014) 0.89
Functional Proteomic Analysis of Repressive Histone Methyltransferase Complexes Reveals ZNF518B as a G9A Regulator. Mol Cell Proteomics (2015) 0.85
Coupling of X-chromosome reactivation with the pluripotent stem cell state. RNA Biol (2014) 0.84
Allelic Imbalance Is a Prevalent and Tissue-Specific Feature of the Mouse Transcriptome. Genetics (2015) 0.84
Xist reduction in breast cancer upregulates AKT phosphorylation via HDAC3-mediated repression of PHLPP1 expression. Oncotarget (2016) 0.83
Sphere formation permits Oct4 reprogramming of ciliary body epithelial cells into induced pluripotent stem cells. Stem Cells Dev (2014) 0.82
Dynamic interplay and function of multiple noncoding genes governing X chromosome inactivation. Biochim Biophys Acta (2015) 0.82
Co-repressor CBFA2T2 regulates pluripotency and germline development. Nature (2016) 0.79
Cis- and trans-regulation in X inactivation. Chromosoma (2015) 0.79
Histone demethylation maintains Prdm14 and Tsix expression and represses xIst in embryonic stem cells. PLoS One (2015) 0.77
ETO family protein Mtgr1 mediates Prdm14 functions in stem cell maintenance and primordial germ cell formation. Elife (2015) 0.77
Unwind and transcribe: chromatin reprogramming in the early mammalian embryo. Curr Opin Genet Dev (2015) 0.76
Xist and Tsix Transcription Dynamics Is Regulated by the X-to-Autosome Ratio and Semistable Transcriptional States. Mol Cell Biol (2016) 0.76
X chromosome reactivation in reprogramming and in development. Curr Opin Cell Biol (2015) 0.76
A high-throughput small molecule screen identifies synergism between DNA methylation and Aurora kinase pathways for X reactivation. Proc Natl Acad Sci U S A (2016) 0.76
Dysregulation of long non-coding RNA in breast cancer: an overview of mechanism and clinical implication. Oncotarget (2016) 0.75
PRDM14 Drives OCT3/4 Recruitment via Active Demethylation in the Transition from Primed to Naive Pluripotency. Stem Cell Reports (2016) 0.75
Identification and Characterization of a PRDM14 Homolog in Japanese Flounder (Paralichthys olivaceus). Int J Mol Sci (2015) 0.75
Sex chromosomes drive gene expression and regulatory dimorphisms in mouse embryonic stem cells. Biol Sex Differ (2017) 0.75
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol (2007) 21.93
Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell (2007) 21.58
The ground state of embryonic stem cell self-renewal. Nature (2008) 19.44
Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell (2008) 16.38
Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome. Science (2008) 13.79
Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse. Cell Stem Cell (2008) 12.45
The human XIST gene: analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus. Cell (1992) 8.05
Naive and primed pluripotent states. Cell Stem Cell (2009) 7.15
A high-efficiency system for the generation and study of human induced pluripotent stem cells. Cell Stem Cell (2008) 5.99
Epigenetic dynamics of imprinted X inactivation during early mouse development. Science (2003) 5.80
Induced pluripotent stem cell generation using a single lentiviral stem cell cassette. Stem Cells (2009) 5.69
Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells. Curr Biol (2001) 5.42
X chromosome dosage compensation: how mammals keep the balance. Annu Rev Genet (2008) 5.18
Induced pluripotency: history, mechanisms, and applications. Genes Dev (2010) 4.89
Targeted mutagenesis of Tsix leads to nonrandom X inactivation. Cell (1999) 4.08
A transient heterochromatic state in Xist preempts X inactivation choice without RNA stabilization. Mol Cell (2006) 3.67
Reactivation of the paternal X chromosome in early mouse embryos. Science (2004) 3.59
Critical function of Prdm14 for the establishment of the germ cell lineage in mice. Nat Genet (2008) 3.52
Intersection of the RNA interference and X-inactivation pathways. Science (2008) 3.43
X-chromosome inactivation and epigenetic fluidity in human embryonic stem cells. Proc Natl Acad Sci U S A (2008) 3.25
The long noncoding RNA, Jpx, is a molecular switch for X chromosome inactivation. Cell (2010) 3.18
Regulation of imprinted X-chromosome inactivation in mice by Tsix. Development (2001) 3.12
Nuclear reprogramming in cells. Science (2008) 3.04
RNF12 is an X-Encoded dose-dependent activator of X chromosome inactivation. Cell (2009) 2.76
Molecular coupling of Xist regulation and pluripotency. Science (2008) 2.74
Female human iPSCs retain an inactive X chromosome. Cell Stem Cell (2010) 2.59
Jpx RNA activates Xist by evicting CTCF. Cell (2013) 2.56
The pluripotency factor Oct4 interacts with Ctcf and also controls X-chromosome pairing and counting. Nature (2009) 2.40
Gene silencing in X-chromosome inactivation: advances in understanding facultative heterochromatin formation. Nat Rev Genet (2011) 2.39
Disruption of imprinted X inactivation by parent-of-origin effects at Tsix. Cell (2000) 2.19
PRDM14 ensures naive pluripotency through dual regulation of signaling and epigenetic pathways in mouse embryonic stem cells. Cell Stem Cell (2013) 1.96
Epigenetic reprogramming in mouse pre-implantation development and primordial germ cells. Development (2012) 1.94
Sequence-specific regulator Prdm14 safeguards mouse ESCs from entering extraembryonic endoderm fates. Nat Struct Mol Biol (2010) 1.88
Homozygous Tsix mutant mice reveal a sex-ratio distortion and revert to random X-inactivation. Nat Genet (2002) 1.78
Parallel mechanisms of epigenetic reprogramming in the germline. Trends Genet (2012) 1.74
An X-linked GFP transgene reveals unexpected paternal X-chromosome activity in trophoblastic giant cells of the mouse placenta. Genesis (2001) 1.73
Molecular coupling of Tsix regulation and pluripotency. Nature (2010) 1.69
Maternal Rnf12/RLIM is required for imprinted X-chromosome inactivation in mice. Nature (2010) 1.64
X chromosome reactivation initiates in nascent primordial germ cells in mice. PLoS Genet (2007) 1.63
RNF12 activates Xist and is essential for X chromosome inactivation. PLoS Genet (2011) 1.56
Epiblast stem cell-based system reveals reprogramming synergy of germline factors. Cell Stem Cell (2012) 1.54
RNF12 initiates X-chromosome inactivation by targeting REX1 for degradation. Nature (2012) 1.50
Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation. EMBO Rep (2013) 1.39
X chromosome activity in mouse XX primordial germ cells. PLoS Genet (2008) 1.38
Derivation conditions impact X-inactivation status in female human induced pluripotent stem cells. Cell Stem Cell (2012) 1.35
Detection of nascent RNA, single-copy DNA and protein localization by immunoFISH in mouse germ cells and preimplantation embryos. Nat Protoc (2011) 1.29
Molecular signatures of human induced pluripotent stem cells highlight sex differences and cancer genes. Cell Stem Cell (2012) 1.23
Tsix transcription- versus RNA-based mechanisms in Xist repression and epigenetic choice. Curr Biol (2004) 1.22
X-inactivation and X-reactivation: epigenetic hallmarks of mammalian reproduction and pluripotent stem cells. Hum Genet (2011) 1.14
X chromosome inactivation in the cycle of life. Development (2012) 1.05
A PRC2-dependent repressive role of PRDM14 in human embryonic stem cells and induced pluripotent stem cell reprogramming. Stem Cells (2013) 1.01
A role for non-coding Tsix transcription in partitioning chromatin domains within the mouse X-inactivation centre. Epigenetics Chromatin (2009) 0.97
Lineage-specific function of the noncoding Tsix RNA for Xist repression and Xi reactivation in mice. Genes Dev (2011) 0.96
Rex1/Zfp42 as an epigenetic regulator for genomic imprinting. Hum Mol Genet (2011) 0.96
The pluripotency factor-bound intron 1 of Xist is dispensable for X chromosome inactivation and reactivation in vitro and in vivo. Cell Rep (2013) 0.92
Synergy of Eed and Tsix in the repression of Xist gene and X-chromosome inactivation. EMBO J (2008) 0.86
Switching stem cell state through programmed germ cell reprogramming. Differentiation (2011) 0.80