Published in Cell on September 29, 2000
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Protein-coding genes are epigenetically regulated in Arabidopsis polyploids. Proc Natl Acad Sci U S A (2001) 2.75
Genomic imprinting mechanisms in mammals. Mutat Res (2008) 2.28
The Polycomb group protein EED is dispensable for the initiation of random X-chromosome inactivation. PLoS Genet (2006) 2.08
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Tsix transcription across the Xist gene alters chromatin conformation without affecting Xist transcription: implications for X-chromosome inactivation. Genes Dev (2005) 1.92
Antisense transcription through the Xist locus mediates Tsix function in embryonic stem cells. Mol Cell Biol (2001) 1.86
Higher order chromatin structure at the X-inactivation center via looping DNA. Dev Biol (2008) 1.68
Gracefully ageing at 50, X-chromosome inactivation becomes a paradigm for RNA and chromatin control. Nat Rev Mol Cell Biol (2011) 1.66
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Maternal Rnf12/RLIM is required for imprinted X-chromosome inactivation in mice. Nature (2010) 1.64
X chromosome reactivation initiates in nascent primordial germ cells in mice. PLoS Genet (2007) 1.63
Long noncoding RNAs in cell-fate programming and reprogramming. Cell Stem Cell (2014) 1.47
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Xist imprinting is promoted by the hemizygous (unpaired) state in the male germ line. Proc Natl Acad Sci U S A (2015) 1.44
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Tsx produces a long noncoding RNA and has general functions in the germline, stem cells, and brain. PLoS Genet (2011) 1.37
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A comprehensive transcript map of the mouse Gnas imprinted complex. Genome Res (2003) 1.32
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Identification of developmentally specific enhancers for Tsix in the regulation of X chromosome inactivation. Mol Cell Biol (2005) 1.30
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Identification of TSIX, encoding an RNA antisense to human XIST, reveals differences from its murine counterpart: implications for X inactivation. Am J Hum Genet (2001) 1.26
Differential methylation of Xite and CTCF sites in Tsix mirrors the pattern of X-inactivation choice in mice. Mol Cell Biol (2006) 1.20
Heterochromatin on the inactive X chromosome delays replication timing without affecting origin usage. Proc Natl Acad Sci U S A (2004) 1.16
Embryonic stem cell-like cells established by culture of adult ovarian cells in mice. Fertil Steril (2010) 1.15
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Essential role of the CUL4B ubiquitin ligase in extra-embryonic tissue development during mouse embryogenesis. Cell Res (2012) 1.12
Physiological roles of long noncoding RNAs: insight from knockout mice. Trends Cell Biol (2014) 1.12
Species differences in TSIX/Tsix reveal the roles of these genes in X-chromosome inactivation. Am J Hum Genet (2002) 1.09
Skewing X chromosome choice by modulating sense transcription across the Xist locus. Genes Dev (2003) 1.09
The demoiselle of X-inactivation: 50 years old and as trendy and mesmerising as ever. PLoS Genet (2011) 1.08
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The search for a marsupial XIC reveals a break with vertebrate synteny. Chromosome Res (2007) 1.06
The rhox homeobox gene cluster is imprinted and selectively targeted for regulation by histone h1 and DNA methylation. Mol Cell Biol (2011) 1.05
Advances in understanding chromosome silencing by the long non-coding RNA Xist. Philos Trans R Soc Lond B Biol Sci (2013) 1.04
Paternally biased X inactivation in mouse neonatal brain. Genome Biol (2010) 1.03
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Tsix RNA and the germline factor, PRDM14, link X reactivation and stem cell reprogramming. Mol Cell (2013) 1.01
Differentiation-dependent requirement of Tsix long non-coding RNA in imprinted X-chromosome inactivation. Nat Commun (2014) 0.98
Sex chromosome inactivation in the male. Epigenetics (2009) 0.97
Lineage-specific function of the noncoding Tsix RNA for Xist repression and Xi reactivation in mice. Genes Dev (2011) 0.96
Guided by RNAs: X-inactivation as a model for lncRNA function. J Mol Biol (2013) 0.96
Rex1/Zfp42 as an epigenetic regulator for genomic imprinting. Hum Mol Genet (2011) 0.96
Epigenetic asymmetry in the mammalian zygote and early embryo: relationship to lineage commitment? Philos Trans R Soc Lond B Biol Sci (2003) 0.96
X-chromosome epigenetic reprogramming in pluripotent stem cells via noncoding genes. Semin Cell Dev Biol (2011) 0.96
A Primary Role for the Tsix lncRNA in Maintaining Random X-Chromosome Inactivation. Cell Rep (2015) 0.95
Deletion of Snai2 and Snai3 results in impaired physical development compounded by lymphocyte deficiency. PLoS One (2013) 0.92
Long nonoding RNAs in the X-inactivation center. Chromosome Res (2013) 0.92
Retinoic acid accelerates downregulation of the Xist repressor, Oct4, and increases the likelihood of Xist activation when Tsix is deficient. BMC Dev Biol (2010) 0.92
Expression of X-linked genes in deceased neonates and surviving cloned female piglets. Mol Reprod Dev (2008) 0.90
The KLHL1-antisense transcript ( KLHL1AS) is evolutionarily conserved. Mamm Genome (2002) 0.90
Mapping of DNA replication origins to noncoding genes of the X-inactivation center. Mol Cell Biol (2006) 0.87
XCI in preimplantation mouse and human embryos: first there is remodelling…. Hum Genet (2011) 0.85
Ftx is dispensable for imprinted X-chromosome inactivation in preimplantation mouse embryos. Sci Rep (2014) 0.84
Coupling of X-chromosome reactivation with the pluripotent stem cell state. RNA Biol (2014) 0.84
Identification of an imprinted gene cluster in the X-inactivation center. PLoS One (2013) 0.82
Dynamic interplay and function of multiple noncoding genes governing X chromosome inactivation. Biochim Biophys Acta (2015) 0.82
Long noncoding RNAs during normal and malignant hematopoiesis. Int J Hematol (2014) 0.82
What makes the maternal X chromosome resistant to undergoing imprinted X inactivation? Philos Trans R Soc Lond B Biol Sci (2017) 0.80
An ex vivo model for imprinting: mutually exclusive binding of Cdx2 and Oct4 as a switch for imprinted and random X-inactivation. Genetics (2012) 0.80
Recent advances in X-chromosome inactivation. J Cell Physiol (2011) 0.79
Expression of XIST sense and antisense in bovine fetal organs and cell cultures. Chromosome Res (2004) 0.79
Antagonist Xist and Tsix co-transcription during mouse oogenesis and maternal Xist expression during pre-implantation development calls into question the nature of the maternal imprint on the X chromosome. Epigenetics (2015) 0.78
Making sense (and antisense) of the X inactivation center. Proc Natl Acad Sci U S A (2001) 0.78
Female mice lacking Xist RNA show partial dosage compensation and survive to term. Genes Dev (2016) 0.78
Investigating long noncoding RNAs using animal models. J Clin Invest (2016) 0.75
Histone H3 Lysine 36 Trimethylation Is Established over the Xist Promoter by Antisense Tsix Transcription and Contributes to Repressing Xist Expression. Mol Cell Biol (2015) 0.75
Trisomy Xp and partial tetrasomy Xq resulting from gain of a rearranged X chromosome in a female fetus: pathogenic or not? Mol Cytogenet (2015) 0.75