PubRank

Marc I Diamond

Author PubWeight™ 51.70‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Propagation of tau misfolding from the outside to the inside of a cell. J Biol Chem 2009 5.76
2 Prion-like mechanisms in neurodegenerative diseases. Nat Rev Neurosci 2009 3.68
3 Trans-cellular propagation of Tau aggregation by fibrillar species. J Biol Chem 2012 2.42
4 Conformational diversity of wild-type Tau fibrils specified by templated conformation change. J Biol Chem 2008 2.34
5 In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice. J Neurosci 2011 2.00
6 Polyglutamine diseases: emerging concepts in pathogenesis and therapy. Hum Mol Genet 2007 1.95
7 The structural basis of androgen receptor activation: intramolecular and intermolecular amino-carboxy interactions. Proc Natl Acad Sci U S A 2005 1.89
8 Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds. Proc Natl Acad Sci U S A 2013 1.88
9 Mechanisms of protein seeding in neurodegenerative diseases. JAMA Neurol 2013 1.51
10 Interaction with polyglutamine aggregates reveals a Q/N-rich domain in TDP-43. J Biol Chem 2010 1.47
11 A rapid cellular FRET assay of polyglutamine aggregation identifies a novel inhibitor. Neuron 2003 1.45
12 Soluble androgen receptor oligomers underlie pathology in a mouse model of spinobulbar muscular atrophy. J Biol Chem 2006 1.41
13 Non-competitive androgen receptor inhibition in vitro and in vivo. Proc Natl Acad Sci U S A 2009 1.37
14 Phosphorylation of profilin by ROCK1 regulates polyglutamine aggregation. Mol Cell Biol 2008 1.35
15 Y-27632 improves rotarod performance and reduces huntingtin levels in R6/2 mice. Neurobiol Dis 2009 1.16
16 Biologically active molecules that reduce polyglutamine aggregation and toxicity. Hum Mol Genet 2006 1.14
17 Selective activation of estrogen receptor-beta transcriptional pathways by an herbal extract. Endocrinology 2006 1.04
18 A cellular conformation-based screen for androgen receptor inhibitors. ACS Chem Biol 2008 1.03
19 Cellular mechanisms of protein aggregate propagation. Curr Opin Neurol 2012 1.01
20 Prion-like nuclear aggregation of TDP-43 during heat shock is regulated by HSP40/70 chaperones. Hum Mol Genet 2013 0.99
21 An N-terminal nuclear export signal regulates trafficking and aggregation of Huntingtin (Htt) protein exon 1. J Biol Chem 2013 0.99
22 ROCK and PRK-2 mediate the inhibitory effect of Y-27632 on polyglutamine aggregation. FEBS Lett 2008 0.98
23 Huntington disease and the huntingtin protein. Prog Mol Biol Transl Sci 2012 0.95
24 Discovery of selective glucocorticoid receptor modulators by multiplexed reporter screening. Proc Natl Acad Sci U S A 2009 0.93
25 A common motif targets huntingtin and the androgen receptor to the proteasome. J Biol Chem 2008 0.92
26 AR inhibitors identified by high-throughput microscopy detection of conformational change and subcellular localization. ACS Chem Biol 2009 0.90
27 F-actin binding regions on the androgen receptor and huntingtin increase aggregation and alter aggregate characteristics. PLoS One 2010 0.90
28 Design and implementation of cell-based assays to model human disease. ACS Chem Biol 2007 0.89
29 Prion-like propagation of protein aggregation and related therapeutic strategies. Neurotherapeutics 2013 0.88
30 Intravitreal administration of HA-1077, a ROCK inhibitor, improves retinal function in a mouse model of huntington disease. PLoS One 2013 0.86
31 The expanding realm of prion phenomena in neurodegenerative disease. Prion 2009 0.86
32 An aggregation sensing reporter identifies leflunomide and teriflunomide as polyglutamine aggregate inhibitors. Hum Mol Genet 2011 0.84
33 Amyotrophic lateral sclerosis and organ donation: is there risk of disease transmission? Ann Neurol 2012 0.79
34 Advances in diagnostic testing for Alzheimer disease. Mo Med 2013 0.78
35 Protein phosphatase 1 dephosphorylates profilin-1 at Ser-137. PLoS One 2012 0.77
36 A strong consensus has emerged around the role of protein misfolding and aggregation in the pathogenesis of neurodegeneration. Introduction. Neurotherapeutics 2013 0.75