Review of the accumulated PLATO documentation supports reliable and consistent superiority of ticagrelor over clopidogrel in patients with acute coronary syndrome: Commentary on: DiNicolantonio JJ, Tomek A, Inactivations, deletions, non-adjudications, and downgrades of clinical endpoints on ticagrelor: serious concerns over the reliability of the PLATO trial, International Journal of Cardiology, 2013.

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Published in Int J Cardiol on November 13, 2013

Authors

Lars Wallentin1, Richard C Becker2, Christopher P Cannon3, Claes Held4, Anders Himmelmann5, Steen Husted6, Stefan K James4, Hugo S Katus7, Kenneth W Mahaffey8, Karen S Pieper2, Robert F Storey9, Philippe Gabriel Steg10, Robert A Harrington8

Author Affiliations

1: Department of Medical Sciences, Cardiology and Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden. Electronic address: Lars.Wallentin@ucr.uu.se.
2: Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA.
3: Thrombolysis in Myocardial Infarction (TIMI) Study Group, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
4: Department of Medical Sciences, Cardiology and Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.
5: AstraZeneca Research and Development, Mölndal, Sweden.
6: Medical Department, Hospital Unit West, Herning/Holstbro, Denmark.
7: Medizinishe Klinik, Universitätsklinikum Heidelberg, Heidelberg, Germany.
8: Department of Medicine, Stanford University, Stanford, CA, USA.
9: Department of Cardiovascular Science, University of Sheffield, Sheffield, United Kingdom.
10: INSERM-Unité 698, Paris, France; Assistance Publique-Hôpitaux de Paris, Département Hospitalo-Universitaire FIRE, Hôpital Bichat, Paris, France; Université Paris-Diderot, Sorbonne-Paris Cité, Paris, France.

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