Published in Cell Cycle on December 04, 2013
Resveratrol protects vascular smooth muscle cells against high glucose-induced oxidative stress and cell proliferation in vitro. Med Sci Monit Basic Res (2014) 1.10
Resveratrol inhibits breast cancer stem-like cells and induces autophagy via suppressing Wnt/β-catenin signaling pathway. PLoS One (2014) 0.94
Resveratrol protects astrocytes against traumatic brain injury through inhibiting apoptotic and autophagic cell death. Cell Death Dis (2014) 0.92
The combination of rapamycin and resveratrol blocks autophagy and induces apoptosis in breast cancer cells. J Cell Biochem (2015) 0.90
Phosphoproteomics reveals resveratrol-dependent inhibition of Akt/mTORC1/S6K1 signaling. J Proteome Res (2014) 0.88
Inhibition of mTOR reduce Stat3 and PAI related angiogenesis in salivary gland adenoid cystic carcinoma. Am J Cancer Res (2014) 0.86
Therapeutic targeting of cellular metabolism in cells with hyperactive mTORC1: a paradigm shift. Mol Cancer Res (2014) 0.85
ERRα Is a Marker of Tamoxifen Response and Survival in Triple-Negative Breast Cancer. Clin Cancer Res (2015) 0.80
Management of lymphangioleiomyomatosis. F1000Prime Rep (2014) 0.79
Effects of Combining Rapamycin and Resveratrol on Apoptosis and Growth of TSC2-Deficient Xenograft Tumors. Am J Respir Cell Mol Biol (2015) 0.76
Resveratrol attenuates neuronal autophagy and inflammatory injury by inhibiting the TLR4/NF-κB signaling pathway in experimental traumatic brain injury. Int J Mol Med (2016) 0.76
Estrogen induces RAD51C expression and localization to sites of DNA damage. Cell Cycle (2016) 0.75
Recent Advances and Challenges of mTOR Inhibitors Use in the Treatment of Patients with Tuberous Sclerosis Complex. Oxid Med Cell Longev (2017) 0.75
The therapeutic potential of resveratrol: a review of clinical trials. NPJ Precis Oncol (2017) 0.75
Resveratrol improves health and survival of mice on a high-calorie diet. Nature (2006) 20.91
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Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy. Mol Biol Cell (2009) 9.14
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Recent progress in the biology and physiology of sirtuins. Nature (2009) 7.73
Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex. Genes Dev (2004) 7.51
ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy. J Biol Chem (2009) 6.34
The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis. Nat Cell Biol (2007) 6.22
Rheb binds and regulates the mTOR kinase. Curr Biol (2005) 6.09
Loss of Tsc1/Tsc2 activates mTOR and disrupts PI3K-Akt signaling through downregulation of PDGFR. J Clin Invest (2003) 6.04
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Mutations in the tuberous sclerosis complex gene TSC2 are a cause of sporadic pulmonary lymphangioleiomyomatosis. Proc Natl Acad Sci U S A (2000) 4.30
Resveratrol stimulates AMP kinase activity in neurons. Proc Natl Acad Sci U S A (2007) 4.24
Lymphangioleiomyomatosis: a clinical update. Chest (2008) 3.79
Tumorigenesis in tuberous sclerosis complex is autophagy and p62/sequestosome 1 (SQSTM1)-dependent. Proc Natl Acad Sci U S A (2011) 2.73
Cancer prevention and treatment with resveratrol: from rodent studies to clinical trials. Cancer Prev Res (Phila) (2009) 2.11
Mutation in TSC2 and activation of mammalian target of rapamycin signalling pathway in renal angiomyolipoma. Lancet (2003) 2.09
Lymphangioleiomyomatosis. Cancer Control (2006) 1.97
Estrogen promotes the survival and pulmonary metastasis of tuberin-null cells. Proc Natl Acad Sci U S A (2009) 1.75
SIRT1 negatively regulates the mammalian target of rapamycin. PLoS One (2010) 1.68
Resveratrol prevents the prohypertrophic effects of oxidative stress on LKB1. Circulation (2009) 1.62
Inhibition of mammalian S6 kinase by resveratrol suppresses autophagy. Aging (Albany NY) (2009) 1.62
At concentrations that inhibit mTOR, resveratrol suppresses cellular senescence. Cell Cycle (2009) 1.54
mTOR signaling for biological control and cancer. J Cell Physiol (2013) 1.40
Resveratrol inhibits mTOR signaling by promoting the interaction between mTOR and DEPTOR. J Biol Chem (2010) 1.35
Coordinate autophagy and mTOR pathway inhibition enhances cell death in melanoma. PLoS One (2013) 1.32
Mammalian target of rapamycin and S6 kinase 1 positively regulate 6-thioguanine-induced autophagy. Cancer Res (2008) 1.26
Abnormal growth of smooth muscle-like cells in lymphangioleiomyomatosis: Role for tumor suppressor TSC2. Am J Respir Cell Mol Biol (2006) 1.24
Macroautophagy signaling and regulation. Curr Top Microbiol Immunol (2009) 1.17
Resveratrol-induced cellular apoptosis and cell cycle arrest in neuroblastoma cells and antitumor effects on neuroblastoma in mice. Surgery (2004) 1.16
Trends in the prevalence of tuberous sclerosis complex manifestations: an epidemiological study of 166 Japanese patients. PLoS One (2013) 1.15
Autophagy takes flight in Drosophila. FEBS Lett (2010) 1.15
The inhibition of phosphatidylinositol 3-kinase by quercetin and analogs. Biochem Biophys Res Commun (1992) 1.09
Resveratrol potentiates rapamycin to prevent hyperinsulinemia and obesity in male mice on high fat diet. Cell Death Dis (2013) 1.02
Resveratrol-induced cell inhibition of growth and apoptosis in MCF7 human breast cancer cells are associated with modulation of phosphorylated Akt and caspase-9. Appl Biochem Biotechnol (2006) 0.99
Non-penetrance in tuberous sclerosis. Lancet (2000) 0.99
The role of S6K1 in ER-positive breast cancer. Cell Cycle (2012) 0.98
Autophagy: an 'Achilles' heel of tumorigenesis in TSC and LAM. Autophagy (2011) 0.97
Phytoestrogen exposure elevates PTEN levels. Hum Mol Genet (2005) 0.96
Clinical trials for rare lung diseases: lessons from lymphangioleiomyomatosis. Lymphat Res Biol (2010) 0.81