Shinji Kihara

Author PubWeight™ 196.69‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Diet-induced insulin resistance in mice lacking adiponectin/ACRP30. Nat Med 2002 8.95
2 Retracted Visfatin: a protein secreted by visceral fat that mimics the effects of insulin. Science 2004 7.21
3 Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms. Nat Med 2005 6.04
4 Association of hypoadiponectinemia with coronary artery disease in men. Arterioscler Thromb Vasc Biol 2003 4.86
5 Adiponectin stimulates angiogenesis by promoting cross-talk between AMP-activated protein kinase and Akt signaling in endothelial cells. J Biol Chem 2003 4.38
6 Adiponectin-mediated modulation of hypertrophic signals in the heart. Nat Med 2004 4.05
7 Obesity, adiponectin and vascular inflammatory disease. Curr Opin Lipidol 2003 3.89
8 Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice. Circulation 2002 3.81
9 Adiponectin and metabolic syndrome. Arterioscler Thromb Vasc Biol 2003 3.78
10 Reciprocal association of C-reactive protein with adiponectin in blood stream and adipose tissue. Circulation 2003 3.73
11 Selective suppression of endothelial cell apoptosis by the high molecular weight form of adiponectin. Circ Res 2004 3.16
12 Role of adiponectin in preventing vascular stenosis. The missing link of adipo-vascular axis. J Biol Chem 2002 3.05
13 Adiponectin stimulates angiogenesis in response to tissue ischemia through stimulation of amp-activated protein kinase signaling. J Biol Chem 2004 3.01
14 Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis. Proc Natl Acad Sci U S A 2004 2.85
15 Adiponectin inhibits the production of CXC receptor 3 chemokine ligands in macrophages and reduces T-lymphocyte recruitment in atherogenesis. Circ Res 2007 2.66
16 Hypoadiponectinemia is an independent risk factor for hypertension. Hypertension 2004 2.65
17 Adiponectin specifically increased tissue inhibitor of metalloproteinase-1 through interleukin-10 expression in human macrophages. Circulation 2004 2.58
18 Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin. Gastroenterology 2003 2.53
19 Androgens decrease plasma adiponectin, an insulin-sensitizing adipocyte-derived protein. Diabetes 2002 2.49
20 Adiponectin, metabolic risk factors, and cardiovascular events among patients with end-stage renal disease. J Am Soc Nephrol 2002 2.46
21 Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor-BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell. Circulation 2002 2.40
22 Adiponectin modulates inflammatory reactions via calreticulin receptor-dependent clearance of early apoptotic bodies. J Clin Invest 2007 2.37
23 Association of serum adiponectin levels with breast cancer risk. Clin Cancer Res 2003 2.35
24 Association of hypoadiponectinemia with impaired vasoreactivity. Hypertension 2003 2.32
25 Adiponectin: a key adipocytokine in metabolic syndrome. Clin Sci (Lond) 2006 2.31
26 Adiponectin inhibits endothelial synthesis of interleukin-8. Circ Res 2005 2.28
27 Effect of moderate alcohol consumption on adiponectin, tumor necrosis factor-alpha, and insulin sensitivity. Diabetes Care 2004 2.24
28 Adiponectin replenishment ameliorates obesity-related hypertension. Hypertension 2006 2.24
29 Adiponectin as a biomarker of the metabolic syndrome. Circ J 2004 2.22
30 Adiponectin suppresses pathological microvessel formation in retina through modulation of tumor necrosis factor-alpha expression. Circ Res 2009 1.86
31 Effect of adiponectin on murine colitis induced by dextran sulfate sodium. Gastroenterology 2006 1.86
32 Clinical significance of high-molecular weight form of adiponectin in male patients with coronary artery disease. Circ J 2008 1.81
33 Adiponectin deficiency increases allergic airway inflammation and pulmonary vascular remodeling. Am J Respir Cell Mol Biol 2009 1.65
34 Association of adiponectin mutation with type 2 diabetes: a candidate gene for the insulin resistance syndrome. Diabetes 2002 1.63
35 Aquaporin 7 deficiency is associated with development of obesity through activation of adipose glycerol kinase. Proc Natl Acad Sci U S A 2005 1.60
36 Adiponectin protects against the development of systolic dysfunction following myocardial infarction. J Mol Cell Cardiol 2007 1.55
37 Retraction. Science 2007 1.48
38 The heart requires glycerol as an energy substrate through aquaporin 7, a glycerol facilitator. Cardiovasc Res 2009 1.45
39 Lower serum level of adiponectin is associated with increased risk of endoscopic erosive gastritis. Dig Dis Sci 2011 1.43
40 Executive summary of the Japan Atherosclerosis Society (JAS) guidelines for the diagnosis and prevention of atherosclerotic cardiovascular diseases in Japan -2012 version. J Atheroscler Thromb 2013 1.42
41 Blockade of mineralocorticoid receptor reverses adipocyte dysfunction and insulin resistance in obese mice. Cardiovasc Res 2009 1.41
42 Adiponectin promotes revascularization of ischemic muscle through a cyclooxygenase 2-dependent mechanism. Mol Cell Biol 2009 1.40
43 Adiponectin protects against angiotensin II-induced cardiac fibrosis through activation of PPAR-alpha. Arterioscler Thromb Vasc Biol 2008 1.39
44 Exacerbation of albuminuria and renal fibrosis in subtotal renal ablation model of adiponectin-knockout mice. Arterioscler Thromb Vasc Biol 2007 1.35
45 Coordinated regulation of fat-specific and liver-specific glycerol channels, aquaporin adipose and aquaporin 9. Diabetes 2002 1.33
46 Adiponectin accumulates in myocardial tissue that has been damaged by ischemia-reperfusion injury via leakage from the vascular compartment. Cardiovasc Res 2007 1.30
47 Adiponectin and renal function, and implication as a risk of cardiovascular disease. Am J Cardiol 2006 1.30
48 Periadventitial adipose tissue plays a critical role in vascular remodeling. Circ Res 2009 1.26
49 Effect of pravastatin on the development of diabetes and adiponectin production. Atherosclerosis 2007 1.26
50 Adaptation to fasting by glycerol transport through aquaporin 7 in adipose tissue. Proc Natl Acad Sci U S A 2004 1.23
51 Reduction of visceral fat is associated with decrease in the number of metabolic risk factors in Japanese men. Diabetes Care 2007 1.20
52 Relationship between the serum uric acid level, visceral fat accumulation and serum adiponectin concentration in Japanese men. Intern Med 2008 1.18
53 Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. 1999. Biochem Biophys Res Commun 2012 1.18
54 Caloric restriction stimulates revascularization in response to ischemia via adiponectin-mediated activation of endothelial nitric-oxide synthase. J Biol Chem 2008 1.18
55 Adiponectin down-regulates acyl-coenzyme A:cholesterol acyltransferase-1 in cultured human monocyte-derived macrophages. Biochem Biophys Res Commun 2004 1.16
56 Human aquaporin adipose (AQPap) gene. Genomic structure, promoter analysis and functional mutation. Eur J Biochem 2002 1.16
57 Adiponectin prevents atherosclerosis by increasing cholesterol efflux from macrophages. Biochem Biophys Res Commun 2008 1.14
58 Adiponectin deficiency suppresses ABCA1 expression and ApoA-I synthesis in the liver. FEBS Lett 2007 1.13
59 Small heterodimer partner, an orphan nuclear receptor, augments peroxisome proliferator-activated receptor gamma transactivation. J Biol Chem 2001 1.13
60 Association of adiponectin and resistin with cardiovascular events in Korean patients with type 2 diabetes: the Korean atherosclerosis study (KAS): a 42-month prospective study. Atherosclerosis 2006 1.13
61 Visfatin in adipocytes is upregulated by hypoxia through HIF1alpha-dependent mechanism. Biochem Biophys Res Commun 2006 1.11
62 Adiponectin is markedly increased in patients with nephrotic syndrome and is related to metabolic risk factors. Kidney Int Suppl 2003 1.10
63 Hypoadiponectinemia accelerates hepatic tumor formation in a nonalcoholic steatohepatitis mouse model. J Hepatol 2007 1.09
64 Effects of peroxisome proliferator-activated receptor ligands, bezafibrate and fenofibrate, on adiponectin level. Arterioscler Thromb Vasc Biol 2006 1.09
65 Usefulness of adiponectin to predict myocardial salvage following successful reperfusion in patients with acute myocardial infarction. Am J Cardiol 2008 1.09
66 Association of hypoadiponectinemia with smoking habit in men. Hypertension 2005 1.08
67 Adiponectin I164T mutation is associated with the metabolic syndrome and coronary artery disease. J Am Coll Cardiol 2004 1.07
68 Circulating omentin is associated with coronary artery disease in men. Atherosclerosis 2011 1.07
69 Adiponectin accelerates reverse cholesterol transport by increasing high density lipoprotein assembly in the liver. Biochem Biophys Res Commun 2007 1.05
70 Effects of adiponectin on the renal sympathetic nerve activity and blood pressure in rats. Exp Biol Med (Maywood) 2007 1.05
71 Disturbed secretion of mutant adiponectin associated with the metabolic syndrome. Biochem Biophys Res Commun 2003 1.05
72 Adiponectin ameliorates hypoxia-induced pulmonary arterial remodeling. Biochem Biophys Res Commun 2009 1.04
73 Adiponectin promotes endothelial progenitor cell number and function. FEBS Lett 2008 1.04
74 Cyclooxygenase-2 induction by adiponectin is regulated by a sphingosine kinase-1 dependent mechanism in cardiac myocytes. FEBS Lett 2008 1.03
75 Adiponectin in essential hypertension. J Nephrol 2002 1.03
76 Increment and impairment of adiponectin in renal failure. Cardiovasc Res 2009 1.02
77 Importance of adipocytokines in obesity-related diseases. Horm Res 2003 1.00
78 Dynamic changes of adiponectin and S100A8 levels by the selective peroxisome proliferator-activated receptor-gamma agonist rivoglitazone. Arterioscler Thromb Vasc Biol 2011 0.97
79 Divergent effects of soy protein diet on the expression of adipocytokines. Biochem Biophys Res Commun 2003 0.97
80 Adiponectin and inflammatory markers in peripheral arterial occlusive disease. Atherosclerosis 2006 0.97
81 Foxo1 represses expression of musclin, a skeletal muscle-derived secretory factor. Biochem Biophys Res Commun 2007 0.95
82 Adiponectin deficiency exacerbates lipopolysaccharide/D-galactosamine-induced liver injury in mice. World J Gastroenterol 2006 0.94
83 Pioglitazone improves left ventricular diastolic function in patients with essential hypertension. Am J Hypertens 2005 0.94
84 Nocturnal reduction in circulating adiponectin concentrations related to hypoxic stress in severe obstructive sleep apnea-hypopnea syndrome. Am J Physiol Endocrinol Metab 2008 0.93
85 Adenovirus-mediated gene transfer of adiponectin reduces the severity of collagen-induced arthritis in mice. Biochem Biophys Res Commun 2008 0.93
86 Association of a fat-derived plasma protein omentin with carotid artery intima-media thickness in apparently healthy men. Hypertens Res 2011 0.93
87 Increased plasma HB-EGF associated with obesity and coronary artery disease. Biochem Biophys Res Commun 2002 0.91
88 Adiponectin, hepatocellular dysfunction and insulin sensitivity. Clin Endocrinol (Oxf) 2004 0.91
89 Association of low serum adiponectin levels with erosive esophagitis in men: an analysis of 2405 subjects undergoing physical check-ups. J Gastroenterol 2011 0.91
90 Familial hypercholesterolemia. J Atheroscler Thromb 2013 0.91
91 Delayed liver regeneration after partial hepatectomy in adiponectin knockout mice. Biochem Biophys Res Commun 2008 0.90
92 Omentin as a novel biomarker of metabolic risk factors. Diabetol Metab Syndr 2012 0.90
93 Reciprocal regulation of natriuretic peptide receptors by insulin in adipose cells. Biochem Biophys Res Commun 2010 0.88
94 Adiponectin deficiency enhances colorectal carcinogenesis and liver tumor formation induced by azoxymethane in mice. World J Gastroenterol 2008 0.88
95 Adiponectin inhibits allograft rejection in murine cardiac transplantation. Transplantation 2009 0.88
96 Fat-derived factor omentin stimulates endothelial cell function and ischemia-induced revascularization via endothelial nitric oxide synthase-dependent mechanism. J Biol Chem 2011 0.88
97 Both intrauterine growth restriction and postnatal growth influence childhood serum concentrations of adiponectin. Clin Endocrinol (Oxf) 2004 0.88
98 The genes influencing adiponectin levels also influence risk factors for metabolic syndrome and type 2 diabetes. Hum Biol 2007 0.88
99 Comprehensive risk management for the prevention of cardiovascular disease: executive summary of the Japan Atherosclerosis Society (JAS) guidelines for the diagnosis and prevention of atherosclerotic cardiovascular diseases in Japan -- 2012. J Atheroscler Thromb 2013 0.88
100 Nocturnal falls of adiponectin levels in sleep apnea with abdominal obesity and impact of hypoxia-induced dysregulated adiponectin production in obese murine mesenteric adipose tissue. J Atheroscler Thromb 2010 0.87
101 Measurement of fasting serum apoB-48 levels in normolipidemic and hyperlipidemic subjects by ELISA. J Lipid Res 2003 0.87
102 Protective role of adiponectin against ethanol-induced gastric injury in mice. Am J Physiol Gastrointest Liver Physiol 2012 0.87
103 Adiponectin protein exists in aortic endothelial cells. PLoS One 2013 0.87
104 Determinants of adiponectin levels in patients with chronic systolic heart failure. Am J Cardiol 2010 0.87
105 URB is abundantly expressed in adipose tissue and dysregulated in obesity. Biochem Biophys Res Commun 2008 0.86
106 Diabetes mellitus. Executive summary of the Japan Atherosclerosis Society (JAS) guidelines for the diagnosis and prevention of atherosclerotic cardiovascular diseases in Japan--2012 version. J Atheroscler Thromb 2013 0.86
107 Adiponectin prevents progression of steatohepatitis in mice by regulating oxidative stress and Kupffer cell phenotype polarization. Hepatol Res 2009 0.86
108 Identification of amino-terminal region of adiponectin as a physiologically functional domain. J Cell Biochem 2006 0.85
109 Adiponectin inhibits macrophage tissue factor, a key trigger of thrombosis in disrupted atherosclerotic plaques. Atherosclerosis 2012 0.84
110 Fat accumulation and obesity-related cardiovascular risk factors in middle-aged Japanese men and women. Intern Med 2014 0.83
111 Cardiovascular disease risk factors other than dyslipidemia. Executive summary of the Japan Atherosclerosis Society (JAS) guidelines for the diagnosis and prevention of atherosclerotic cardiovascular diseases in Japan - 2012 version. J Atheroscler Thromb 2013 0.83
112 Diagnostic criteria for dyslipidemia. J Atheroscler Thromb 2013 0.82
113 Treatment B) drug therapy: executive summary of the Japan Atherosclerosis Society(JAS) guidelines for the diagnosis and prevention of atherosclerotic cardiovascular diseases in Japan--2012 version. J Atheroscler Thromb 2013 0.82
114 Treatment A) lifestyle modification: executive summary of the Japan Atherosclerosis Society(JAS) guidelines for the diagnosis and prevention of atherosclerotic cardiovascular diseases in Japan--2012 version. J Atheroscler Thromb 2013 0.81
115 Characteristics of sleep-disordered breathing in Japanese patients with type 2 diabetes mellitus. Metabolism 2009 0.81
116 Adiponectin regulates vascular endothelial growth factor-C expression in macrophages via Syk-ERK pathway. PLoS One 2013 0.81
117 Diagnosis of atherosclerosis. Executive Summary of the Japan Atherosclerosis Society (JAS) Guidelines for the Diagnosis and Prevention of Atherosclerotic Cardiovascular Diseases in Japan―2012 Version. J Atheroscler Thromb 2013 0.81
118 Impact of Remnant Lipoprotein on Coronary Plaque Components. J Atheroscler Thromb 2015 0.79
119 Coronary artery disease. Executive summary of the Japan Atherosclerosis Society (JAS) guidelines for the diagnosis and prevention of atherosclerotic cardiovascular diseases in Japan--2012 version. J Atheroscler Thromb 2013 0.78
120 Other types of primary hyperlipoproteinemia(hyperlipidemia). Executive summary of the Japan Atherosclerosis Society (JAS) guidelines for the diagnosis and prevention of atherosclerotic cardiovascular diseases in Japan--2012 version. J Atheroscler Thromb 2013 0.78
121 Adiponectin deficiency enhanced the severity of cerulein-induced chronic pancreatitis in mice. J Gastroenterol 2010 0.78
122 Adiponectin-mediated modulation of lymphatic vessel formation and lymphedema. J Am Heart Assoc 2013 0.78
123 Adiponectin is independently associated with glycosylated haemoglobin. Eur J Endocrinol 2004 0.77
124 Metabolic syndrome. J Atheroscler Thromb 2013 0.76
125 Autoimmune severe hypertriglyceridemia induced by anti-apolipoprotein C-II antibody. J Clin Endocrinol Metab 2014 0.76
126 Within-pair differences of DNA methylation levels between monozygotic twins are different between male and female pairs. BMC Med Genomics 2016 0.75
127 Statements. J Atheroscler Thromb 2014 0.75
128 Cerebrovascular diseases. J Atheroscler Thromb 2013 0.75
129 Lack of adiponectin promotes formation of cholesterol gallstones in mice. Biochem Biophys Res Commun 2010 0.75
130 Other high-risk conditions. J Atheroscler Thromb 2013 0.75
131 Cystatin C-Adiponectin Complex in Plasma Associates with Coronary Plaque Instability. J Atheroscler Thromb 2017 0.75
132 [Human genetic mutations and polymorphisms of adipocytokines relating to obesity]. Nihon Rinsho 2009 0.75
133 The elderly. J Atheroscler Thromb 2013 0.75
134 A case of adolescent hyperlipoproteinemia with xanthoma and acute pancreatitis, associated with decreased activities of lipoprotein lipase and hepatic triglyceride lipase. Intern Med 2010 0.75
135 Chronic kidney disease. J Atheroscler Thromb 2013 0.75
136 Women. Executive Summary of the Japan Atherosclerosis Society (JAS) Guidelines for the Diagnosis and Prevention of Atherosclerotic Cardiovascular Diseases in Japan―2012 Version. J Atheroscler Thromb 2013 0.75
137 Absolute risk of cardiovascular disease and lipid management targets. J Atheroscler Thromb 2013 0.75
138 [High sensitivity C-reactive protein analysis in th diagnosis of arteriosclerosis]. Nihon Rinsho 2004 0.75