Retraction.

Misconduct accounts for the majority of retracted scientific publications. Proc Natl Acad Sci U S A (2012) 5.89

The secret life of NAD+: an old metabolite controlling new metabolic signaling pathways. Endocr Rev (2009) 3.23

Adipocytokines and the metabolic complications of obesity. J Clin Endocrinol Metab (2008) 3.11

Inflammatory mechanisms in the regulation of insulin resistance. Mol Med (2008) 2.71

Nampt: linking NAD biology, metabolism and cancer. Trends Endocrinol Metab (2008) 2.47

Inflammation, a link between obesity and cardiovascular disease. Mediators Inflamm (2010) 1.80

Nicotinamide phosphoribosyltransferase (Nampt): a link between NAD biology, metabolism, and diseases. Curr Pharm Des (2009) 1.69

The small molecule GMX1778 is a potent inhibitor of NAD+ biosynthesis: strategy for enhanced therapy in nicotinic acid phosphoribosyltransferase 1-deficient tumors. Mol Cell Biol (2009) 1.60

The NAD World: a new systemic regulatory network for metabolism and aging--Sirt1, systemic NAD biosynthesis, and their importance. Cell Biochem Biophys (2009) 1.58

Pharmacological inhibition of nicotinamide phosphoribosyltransferase/visfatin enzymatic activity identifies a new inflammatory pathway linked to NAD. PLoS One (2008) 1.48

SIRT1-dependent regulation of chromatin and transcription: linking NAD(+) metabolism and signaling to the control of cellular functions. Biochim Biophys Acta (2009) 1.41

Skeletal muscle NAMPT is induced by exercise in humans. Am J Physiol Endocrinol Metab (2009) 1.36

Extracellular Nampt promotes macrophage survival via a nonenzymatic interleukin-6/STAT3 signaling mechanism. J Biol Chem (2008) 1.29

The novel adipocytokine visfatin exerts direct cardioprotective effects. J Cell Mol Med (2008) 1.21

Therapeutic potential of SIRT1 and NAMPT-mediated NAD biosynthesis in type 2 diabetes. Front Biosci (Landmark Ed) (2009) 1.12

Visfatin/Nampt: an adipokine with cardiovascular impact. Mediators Inflamm (2013) 1.03

Membrane raft-lysosome redox signalling platforms in coronary endothelial dysfunction induced by adipokine visfatin. Cardiovasc Res (2010) 1.01

Nicotinamide Phosphoribosyltransferase in Human Diseases. J Bioanal Biomed (2011) 1.01

Adipokines and osteoarthritis: novel molecules involved in the pathogenesis and progression of disease. Arthritis (2011) 0.98

Role of adipokines in atherosclerosis: interferences with cardiovascular complications in rheumatic diseases. Mediators Inflamm (2012) 0.95

From heterochromatin islands to the NAD World: a hierarchical view of aging through the functions of mammalian Sirt1 and systemic NAD biosynthesis. Biochim Biophys Acta (2009) 0.92

SIRT1-Mediated eNAMPT Secretion from Adipose Tissue Regulates Hypothalamic NAD+ and Function in Mice. Cell Metab (2015) 0.92

Pre-B cell colony enhancing factor (PBEF), a cytokine with multiple physiological functions. Cytokine Growth Factor Rev (2013) 0.90

Visfatin impairs endothelium-dependent relaxation in rat and human mesenteric microvessels through nicotinamide phosphoribosyltransferase activity. PLoS One (2011) 0.90

Beyond fat mass: exploring the role of adipokines in rheumatic diseases. ScientificWorldJournal (2011) 0.87

Visfatin, glucose metabolism and vascular disease: a review of evidence. Diabetol Metab Syndr (2010) 0.87

Visfatin is induced by peroxisome proliferator-activated receptor gamma in human macrophages. FEBS J (2010) 0.87

Mechanisms linking excess adiposity and carcinogenesis promotion. Front Endocrinol (Lausanne) (2014) 0.86

Proinflammatory actions of visfatin/nicotinamide phosphoribosyltransferase (Nampt) involve regulation of insulin signaling pathway and Nampt enzymatic activity. J Biol Chem (2012) 0.86

New markers of insulin resistance in polycystic ovary syndrome. J Endocrinol Invest (2016) 0.84

Beijing ambient particle exposure accelerates atherosclerosis in ApoE knockout mice by upregulating visfatin expression. Cell Stress Chaperones (2014) 0.83

Expression and regulation of nampt in human islets. PLoS One (2013) 0.83

[Adipokine update - new molecules, new functions]. Wien Med Wochenschr (2010) 0.81

Relationship between cerebrospinal fluid visfatin (PBEF/Nampt) levels and adiposity in humans. Diabetes (2008) 0.81

Resveratrol differentially regulates NAMPT and SIRT1 in Hepatocarcinoma cells and primary human hepatocytes. PLoS One (2014) 0.80

Extracellular nicotinamide phosphoribosyltransferase, a new cancer metabokine. Br J Pharmacol (2016) 0.79

Nutrition, insulin resistance and dysfunctional adipose tissue determine the different components of metabolic syndrome. World J Diabetes (2016) 0.77

Visfatin/PBEF/Nampt: A New Cardiovascular Target? Front Pharmacol (2010) 0.77

Soy food supplementation, dietary fat reduction and peripheral blood gene expression in postmenopausal women--a randomized, controlled trial. Mol Nutr Food Res (2011) 0.76

Effects of short-term dry immersion on bone remodeling markers, insulin and adipokines. PLoS One (2017) 0.75

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell (2006) 120.51

Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell (2007) 101.42

Generation of germline-competent induced pluripotent stem cells. Nature (2007) 32.77

Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol (2007) 21.93

The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell (2003) 17.72

Generation of mouse induced pluripotent stem cells without viral vectors. Science (2008) 15.25

Increased oxidative stress in obesity and its impact on metabolic syndrome. J Clin Invest (2004) 13.42

Generation of pluripotent stem cells from adult mouse liver and stomach cells. Science (2008) 10.55

Suppression of induced pluripotent stem cell generation by the p53-p21 pathway. Nature (2009) 9.75

Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis. Lancet (2007) 9.56

Diet-induced insulin resistance in mice lacking adiponectin/ACRP30. Nat Med (2002) 8.95

Suppression of aging in mice by the hormone Klotho. Science (2005) 8.11

Secretory mechanisms and intercellular transfer of microRNAs in living cells. J Biol Chem (2010) 8.09

A more efficient method to generate integration-free human iPS cells. Nat Methods (2011) 7.39

Nanog is the gateway to the pluripotent ground state. Cell (2009) 7.27

Retracted Visfatin: a protein secreted by visceral fat that mimics the effects of insulin. Science (2004) 7.21

Induction of pluripotent stem cells from fibroblast cultures. Nat Protoc (2007) 7.01

Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation. Diabetes (2007) 6.81

Variation in the safety of induced pluripotent stem cell lines. Nat Biotechnol (2009) 6.39

Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms. Nat Med (2005) 6.04

Association of hypoadiponectinemia with coronary artery disease in men. Arterioscler Thromb Vasc Biol (2003) 4.86

Adiponectin stimulates angiogenesis by promoting cross-talk between AMP-activated protein kinase and Akt signaling in endothelial cells. J Biol Chem (2003) 4.38

Hypoxia enhances the generation of induced pluripotent stem cells. Cell Stem Cell (2009) 4.38

Endoscopic submucosal dissection of early esophageal cancer. Clin Gastroenterol Hepatol (2005) 4.20

Adiponectin-mediated modulation of hypertrophic signals in the heart. Nat Med (2004) 4.05

Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage. Nat Biotechnol (2011) 3.97

Obesity, adiponectin and vascular inflammatory disease. Curr Opin Lipidol (2003) 3.89

Adiponectin stimulates production of nitric oxide in vascular endothelial cells. J Biol Chem (2003) 3.86

Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice. Circulation (2002) 3.81

Adiponectin and metabolic syndrome. Arterioscler Thromb Vasc Biol (2003) 3.78

Reciprocal association of C-reactive protein with adiponectin in blood stream and adipose tissue. Circulation (2003) 3.73

mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells. Mol Cell Biol (2004) 3.72

Adiponectin and development of type 2 diabetes in the Pima Indian population. Lancet (2002) 3.68

Reactivation of the paternal X chromosome in early mouse embryos. Science (2004) 3.59

Autophagy is essential for preimplantation development of mouse embryos. Science (2008) 3.55

Role of hepatic STAT3 in brain-insulin action on hepatic glucose production. Cell Metab (2006) 3.34

Induction of adiponectin, a fat-derived antidiabetic and antiatherogenic factor, by nuclear receptors. Diabetes (2003) 3.28

FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets. J Clin Invest (2008) 3.25