PubRank

Calum A MacRae

Author PubWeight™ 119.99‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet 2009 12.19
2 Variants conferring risk of atrial fibrillation on chromosome 4q25. Nature 2007 8.03
3 Common variants in KCNN3 are associated with lone atrial fibrillation. Nat Genet 2010 3.97
4 Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy. Nat Genet 2004 3.88
5 C/EBPβ controls exercise-induced cardiac growth and protects against pathological cardiac remodeling. Cell 2010 2.68
6 High-throughput assay for small molecules that modulate zebrafish embryonic heart rate. Nat Chem Biol 2005 2.64
7 Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation. Nat Biotechnol 2004 2.57
8 Familial aggregation in lone atrial fibrillation. Hum Genet 2005 2.55
9 Drugs that induce repolarization abnormalities cause bradycardia in zebrafish. Circulation 2003 2.42
10 Utility of amino-terminal pro-brain natriuretic peptide, galectin-3, and apelin for the evaluation of patients with acute heart failure. J Am Coll Cardiol 2006 2.29
11 Locus for atrial fibrillation maps to chromosome 6q14-16. Circulation 2003 2.28
12 Klf2 is an essential regulator of vascular hemodynamic forces in vivo. Dev Cell 2006 2.26
13 Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. J Am Coll Cardiol 2010 2.17
14 Large scale replication and meta-analysis of variants on chromosome 4q25 associated with atrial fibrillation. Eur Heart J 2009 2.06
15 Notch1b and neuregulin are required for specification of central cardiac conduction tissue. Development 2006 2.00
16 RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing. Nat Med 2012 1.97
17 Pattern recognition: combining informatics and genetics to re-evaluate conduction disease. Heart 2012 1.91
18 Fine mapping of the 1p36 deletion syndrome identifies mutation of PRDM16 as a cause of cardiomyopathy. Am J Hum Genet 2013 1.87
19 Genetic variation in the alternative splicing regulator RBM20 is associated with dilated cardiomyopathy. Heart Rhythm 2011 1.85
20 Echocardiographic evaluation in asymptomatic relatives of patients with dilated cardiomyopathy reveals preclinical disease. Ann Intern Med 2005 1.85
21 In vivo recording of adult zebrafish electrocardiogram and assessment of drug-induced QT prolongation. Am J Physiol Heart Circ Physiol 2006 1.77
22 Mutant desmocollin-2 causes arrhythmogenic right ventricular cardiomyopathy. Am J Hum Genet 2006 1.68
23 C-Reactive protein in lone atrial fibrillation. Am J Cardiol 2006 1.68
24 Cardiac sodium channel gene variants and sudden cardiac death in women. Circulation 2007 1.67
25 The MedSeq Project: a randomized trial of integrating whole genome sequencing into clinical medicine. Trials 2014 1.62
26 Closer look at genetic testing in long-QT syndrome: will DNA diagnostics ever be enough? Circulation 2009 1.56
27 ACE I/D polymorphism associated with abnormal atrial and atrioventricular conduction in lone atrial fibrillation and structural heart disease: implications for electrical remodeling. Heart Rhythm 2009 1.55
28 Cardiac sodium channel mutation in atrial fibrillation. Heart Rhythm 2007 1.50
29 Arterial tortuosity syndrome with multiple intracranial aneurysms: a case report. Arch Neurol 2011 1.49
30 Integrin-linked kinase regulates endothelial cell survival and vascular development. Mol Cell Biol 2004 1.46
31 Drug-sensitized zebrafish screen identifies multiple genes, including GINS3, as regulators of myocardial repolarization. Circulation 2009 1.41
32 Human-zebrafish non-coding conserved elements act in vivo to regulate transcription. Nucleic Acids Res 2005 1.39
33 Common variants in cardiac ion channel genes are associated with sudden cardiac death. Circ Arrhythm Electrophysiol 2010 1.22
34 Potassium channel gene mutations rarely cause atrial fibrillation. BMC Med Genet 2006 1.21
35 A systematic approach to the reporting of medically relevant findings from whole genome sequencing. BMC Med Genet 2014 1.14
36 High-resolution cardiovascular function confirms functional orthology of myocardial contractility pathways in zebrafish. Physiol Genomics 2010 1.10
37 Notch signaling regulates cardiomyocyte proliferation during zebrafish heart regeneration. Proc Natl Acad Sci U S A 2014 1.10
38 Defining the pathogenicity of DNA sequence variation. Circ Cardiovasc Genet 2009 1.07
39 Purification of hearts from zebrafish embryos. Biotechniques 2006 1.07
40 Human amyloidogenic light chain proteins result in cardiac dysfunction, cell death, and early mortality in zebrafish. Am J Physiol Heart Circ Physiol 2013 1.06
41 Animal models for arrhythmias. Cardiovasc Res 2005 1.05
42 Human cardiomyopathy mutations induce myocyte hyperplasia and activate hypertrophic pathways during cardiogenesis in zebrafish. Dis Model Mech 2011 1.03
43 Carotid intima-media thickness is associated with premature parental coronary heart disease: the Framingham Heart Study. Circulation 2003 1.02
44 In vivo natriuretic peptide reporter assay identifies chemical modifiers of hypertrophic cardiomyopathy signalling. Cardiovasc Res 2011 1.01
45 Ion channel mutations in AF: signal or noise? Heart Rhythm 2008 0.99
46 Aging syndrome genes and premature coronary artery disease. BMC Med Genet 2005 0.95
47 Techniques for the in vivo assessment of cardio-renal function in zebrafish (Danio rerio) larvae. J Physiol 2012 0.94
48 A novel locus for dilated cardiomyopathy, diffuse myocardial fibrosis, and sudden death on chromosome 10q25-26. J Am Coll Cardiol 2006 0.92
49 A one-page summary report of genome sequencing for the healthy adult. Public Health Genomics 2015 0.92
50 Hedgehog signaling via angiopoietin1 is required for developmental vascular stability. Mech Dev 2010 0.91
51 Arrhythmogenic right ventricular cardiomyopathy. Heart Fail Clin 2010 0.89
52 Next-generation genome-wide association studies: time to focus on phenotype? Circ Cardiovasc Genet 2011 0.88
53 Genetic testing in cardiovascular diseases. Curr Opin Cardiol 2014 0.88
54 Genetics of atrial fibrillation. Med Clin North Am 2008 0.88
55 The genetics of atrial fibrillation. Curr Opin Cardiol 2010 0.87
56 Adrenergic-receptor polymorphisms and heart failure. N Engl J Med 2002 0.87
57 Myocardial blood flow and oxygen consumption in patients with Friedreich's ataxia prior to the onset of cardiomyopathy. Coron Artery Dis 2007 0.86
58 Chemical and metabolomic screens identify novel biomarkers and antidotes for cyanide exposure. FASEB J 2013 0.86
59 The zebrafish: scalable in vivo modeling for systems biology. Wiley Interdiscip Rev Syst Biol Med 2010 0.85
60 Eya4 regulation of Na+/K+-ATPase is required for sensory system development in zebrafish. Development 2008 0.85
61 Differential activation of natriuretic peptide receptors modulates cardiomyocyte proliferation during development. Development 2013 0.84
62 Novel cardiovascular gene functions revealed via systematic phenotype prediction in zebrafish. Development 2014 0.84
63 Acquisition, Analysis, and Sharing of Data in 2015 and Beyond: A Survey of the Landscape: A Conference Report From the American Heart Association Data Summit 2015. J Am Heart Assoc 2015 0.84
64 Prioritizing causal disease genes using unbiased genomic features. Genome Biol 2014 0.82
65 Future translational applications from the contemporary genomics era: a scientific statement from the American Heart Association. Circulation 2015 0.81
66 Comparison of echocardiographic and cardiac magnetic resonance imaging in hypertrophic cardiomyopathy sarcomere mutation carriers without left ventricular hypertrophy. Circ Cardiovasc Genet 2013 0.81
67 Action and the actionability in exome variation. Circ Cardiovasc Genet 2012 0.79
68 Growth arrest specific gene (GAS) 6 modulates platelet thrombus formation and vascular wall homeostasis and represents an attractive drug target. Curr Pharm Des 2007 0.78
69 Symptoms in atrial fibrillation: why keep score? Circ Arrhythm Electrophysiol 2009 0.78
70 Clinical screening and genetic testing. Clin Lab Med 2010 0.77
71 Genetic screening and risk assessment in hypertrophic cardiomyopathy. J Am Coll Cardiol 2004 0.76
72 Lysosomal dysfunction and impaired autophagy underlie the pathogenesis of amyloidogenic light chain-mediated cardiotoxicity. EMBO Mol Med 2015 0.76
73 Sequential effects of spadetail, one-eyed pinhead and no tail on midline convergence of nephric primordia during zebrafish embryogenesis. Dev Biol 2013 0.76
74 Clinical screening and genetic testing. Heart Fail Clin 2010 0.75
75 Risk stratification in the long-QT syndrome. N Engl J Med 2003 0.75
76 Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. J Clin Invest 2017 0.75
77 Management strategy in 249 consecutive patients with obstructive hypertrophic cardiomyopathy referred to a dedicated program. Am J Cardiol 2012 0.75
78 The genetics of cardiomyopathies: what clinicians should know. Curr Heart Fail Rep 2007 0.75
79 A dream, a journey, and a promise: the inauguration of Circulation: Cardiovascular Genetics. Circ Cardiovasc Genet 2008 0.75