Single acetylcholine receptor channel currents recorded at high hydrostatic pressures.

PubWeight™: 0.91‹?›

🔗 View Article (PMC 304842)

Published in Proc Natl Acad Sci U S A on May 01, 1987

Authors

S H Heinemann, W Stühmer, F Conti

Articles cited by this

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch (1981) 134.60

Single-channel currents recorded from membrane of denervated frog muscle fibres. Nature (1976) 13.78

Fast events in single-channel currents activated by acetylcholine and its analogues at the frog muscle end-plate. J Physiol (1985) 9.25

Single acetylcholine-activated channels show burst-kinetics in presence of desensitizing concentrations of agonist. Nature (1980) 6.83

Ion transport through pores: a rate-theory analysis. Biochim Biophys Acta (1973) 4.94

The extracellular patch clamp: a method for resolving currents through individual open channels in biological membranes. Pflugers Arch (1978) 4.42

Open channel noise. I. Noise in acetylcholine receptor currents suggests conformational fluctuations. Biophys J (1985) 3.15

High pressure effects on proteins and other biomolecules. Annu Rev Biophys Bioeng (1982) 1.98

The effects of pressure on the molecular structure and physiological functions of cell membranes. Philos Trans R Soc Lond B Biol Sci (1984) 1.36

Pressure dependence of sodium gating currents in the squid giant axon. Eur Biophys J (1984) 1.36

Pressure dependence of the potassium currents of squid giant axon. J Membr Biol (1982) 1.31

Pressure effects on alamethicin conductance in bilayer membranes. Biophys J (1983) 1.05

Pressure dependence of the sodium currents of squid giant axon. J Membr Biol (1982) 1.05

Slowing of ionic currents in the voltage-clamped squid axon by helium pressure. Nature (1975) 0.99

Permeability properties of chick myotube acetylcholine-activated channels. Biophys J (1984) 0.96

Ion transport by single receptor channels. Cold Spring Harb Symp Quant Biol (1983) 0.94

The effects of hydrostatic pressure on the spontaneous release of transmitter at the frog neuromuscular junction. J Physiol (1982) 0.92

Hydrostatic pressure reduces synaptic efficiency by inhibiting transmitter release. Undersea Biomed Res (1981) 0.91

The action of high hydrostatic pressure on the membrane currents of Helix neurones. J Physiol (1981) 0.89

Articles by these authors

Structural parts involved in activation and inactivation of the sodium channel. Nature (1989) 8.72

Effects of external cations and mutations in the pore region on C-type inactivation of Shaker potassium channels. Receptors Channels (1993) 8.09

Inhibition of Bax channel-forming activity by Bcl-2. Science (1997) 5.10

Calcium channel characteristics conferred on the sodium channel by single mutations. Nature (1992) 4.90

Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel. Nature (1989) 4.55

Single channel recordings of K+ currents in squid axons. Nature (1980) 4.48

Inactivation properties of voltage-gated K+ channels altered by presence of beta-subunit. Nature (1994) 4.38

Potassium and sodium ion current noise in the membrane of the squid giant axon. J Physiol (1975) 4.03

Extracellular K+ specifically modulates a rat brain K+ channel. Proc Natl Acad Sci U S A (1992) 3.66

Electrophysiological recording from Xenopus oocytes. Methods Enzymol (1992) 3.64

Measurement of the conductance of the sodium channel from current fluctuations at the node of Ranvier. J Physiol (1976) 3.46

Depletion of InsP3 stores activates a Ca2+ and K+ current by means of a phosphatase and a diffusible messenger. Nature (1993) 3.39

Ion conduction through C-type inactivated Shaker channels. J Gen Physiol (1997) 3.37

Regulation of fast inactivation of cloned mammalian IK(A) channels by cysteine oxidation. Nature (1991) 3.30

Molecular determinants for activation and inactivation of HERG, a human inward rectifier potassium channel. J Physiol (1996) 3.29

Mapping the site of block by tetrodotoxin and saxitoxin of sodium channel II. FEBS Lett (1991) 3.29

The steady state properties of ion exchange membranes with fixed sites. Biophys J (1965) 3.23

Subthreshold behavior and phenomenological impedance of the squid giant axon. J Gen Physiol (1970) 3.02

Cooperative subunit interactions in C-type inactivation of K channels. Biophys J (1995) 2.84

Oncogenic potential of EAG K(+) channels. EMBO J (1999) 2.74

A single point mutation confers tetrodotoxin and saxitoxin insensitivity on the sodium channel II. FEBS Lett (1989) 2.73

Channel noise in nerve membranes and lipid bilayers. Q Rev Biophys (1975) 2.67

Nonstationary noise analysis and application to patch clamp recordings. Methods Enzymol (1992) 2.60

Ether-à-go-go encodes a voltage-gated channel permeable to K+ and Ca2+ and modulated by cAMP. Nature (1993) 2.55

Pursuing the structure and function of voltage-gated channels. Trends Neurosci (1990) 2.47

IRK(1-3) and GIRK(1-4) inwardly rectifying K+ channel mRNAs are differentially expressed in the adult rat brain. J Neurosci (1996) 2.45

A characterization of the activating structural rearrangements in voltage-dependent Shaker K+ channels. Neuron (1994) 2.38

Gating currents of inactivating and non-inactivating potassium channels expressed in Xenopus oocytes. Pflugers Arch (1991) 2.28

A single negative charge within the pore region of a cGMP-gated channel controls rectification, Ca2+ blockage, and ionic selectivity. Proc Natl Acad Sci U S A (1994) 2.19

Lateral distribution of sodium and potassium channels in frog skeletal muscle: measurements with a patch-clamp technique. J Physiol (1983) 2.18

The muscle chloride channel ClC-1 has a double-barreled appearance that is differentially affected in dominant and recessive myotonia. J Gen Physiol (1999) 2.17

Modulation of potassium channel function by methionine oxidation and reduction. Proc Natl Acad Sci U S A (1997) 2.16

Conductance of the sodium channel in myelinated nerve fibres with modified sodium inactivation. J Physiol (1976) 2.15

The steady-state properties of an ion exchange membrane with mobile sites. Biophys J (1966) 2.09

Primary structure and functional expression of a high voltage activated calcium channel from rabbit lung. FEBS Lett (1990) 2.08

Quantal charge redistributions accompanying the structural transitions of sodium channels. Eur Biophys J (1989) 2.04

P2X4: an ATP-activated ionotropic receptor cloned from rat brain. Proc Natl Acad Sci U S A (1996) 1.98

Functional expression of a rat homologue of the voltage gated either á go-go potassium channel reveals differences in selectivity and activation kinetics between the Drosophila channel and its mammalian counterpart. EMBO J (1994) 1.98

Patch clamp characterization of sodium channels expressed from rat brain cDNA. Eur Biophys J (1987) 1.95

The last few milliseconds in the life of a secretory granule. Docking, dynamics and fusion visualized by total internal reflection fluorescence microscopy (TIRFM). Eur Biophys J (1998) 1.94

Slow sodium channel inactivation in mammalian muscle: a possible role in regulating excitability. Muscle Nerve (1988) 1.80

Conductance fluctuations from the inactivation process of sodium channels in myelinated nerve fibres. J Physiol (1980) 1.75

Comparison between slow sodium channel inactivation in rat slow- and fast-twitch muscle. J Physiol (1987) 1.71

Slow sodium channel inactivation in rat fast-twitch muscle. J Physiol (1987) 1.69

Extracellular Mg2+ regulates activation of rat eag potassium channel. Pflugers Arch (1996) 1.66

Safety and efficacy of raltegravir in HIV-infected transplant patients cotreated with immunosuppressive drugs. Am J Transplant (2009) 1.65

Molecular imaging of rheumatoid arthritis by radiolabelled monoclonal antibodies: new imaging strategies to guide molecular therapies. Eur J Nucl Med Mol Imaging (2009) 1.62

Activation and inactivation of homomeric KvLQT1 potassium channels. Biophys J (1998) 1.61

Role of voltage-gated potassium channels in cancer. J Membr Biol (2005) 1.60

Tracking chromaffin granules on their way through the actin cortex. Eur Biophys J (2000) 1.60

Detection of phospholipid phase separation. A multifrequency phase fluorimetry study of 1,6-diphenyl-1,3,5-hexatriene fluorescence. J Biol Chem (1984) 1.58

Macroscopic Na+ currents in the "Nonconducting" Shaker potassium channel mutant W434F. J Gen Physiol (1998) 1.57

Leishmania in SLE mimicking an exacerbation. Clin Exp Rheumatol (2006) 1.54

Oxidative regulation of large conductance calcium-activated potassium channels. J Gen Physiol (2001) 1.54

Strategy for rapid immobilization of prey by a fish-hunting marine snail. Nature (1996) 1.53

Photobleaching through glass micropipettes: sodium channels without lateral mobility in the sarcolemma of frog skeletal muscle. Proc Natl Acad Sci U S A (1982) 1.53

Patch-clamping of the inner mitochondrial membrane reveals a voltage-dependent ion channel. Nature (1988) 1.51

Disposition of metformin (N,N-dimethylbiguanide) in man. Clin Pharmacol Ther (1978) 1.50

Slow changes in currents through sodium channels in frog muscle membrane. J Physiol (1983) 1.47

Multiple PIP2 binding sites in Kir2.1 inwardly rectifying potassium channels. FEBS Lett (2001) 1.47

Modification of C-type inactivating Shaker potassium channels by chloramine-T. Pflugers Arch (1996) 1.46

Characterization of recombinant human P2X4 receptor reveals pharmacological differences to the rat homologue. Mol Pharmacol (1997) 1.44

Inward rectifier potassium channels in plants differ from their animal counterparts in response to voltage and channel modulators. Eur Biophys J (1995) 1.42

Structure of the squid axon membrane as derived from charge-pulse relaxation studies in the presence of absorbed lipophilic ions. J Membr Biol (1981) 1.42

Time-resolved fluorescence emission spectra of Laurdan in phospholipid vesicles by multifrequency phase and modulation fluorometry. Cell Mol Biol (1986) 1.41

Evidence for the detrimental role of proteolysis during liver preservation in humans. Gastroenterology (1995) 1.40

Biological activity of chitosan: ultrastructural study. Biomaterials (1988) 1.39

Nerve fiber behaviour in heavy water under voltage-clamp. Biophysik (1968) 1.39

The inhibitory effect of the antipsychotic drug haloperidol on HERG potassium channels expressed in Xenopus oocytes. Br J Pharmacol (1997) 1.38

Effects of imipramine on ion channels and proliferation of IGR1 melanoma cells. J Membr Biol (2002) 1.37

Pressure dependence of sodium gating currents in the squid giant axon. Eur Biophys J (1984) 1.36

Pore properties of rat brain II sodium channels mutated in the selectivity filter domain. Eur Biophys J (1996) 1.34

Characterization of an eag-like potassium channel in human neuroblastoma cells. J Physiol (1998) 1.33

Temperature and pressure dependence of Shaker K+ channel N- and C-type inactivation. Eur Biophys J (1997) 1.32

Amino terminal-dependent gating of the potassium channel rat eag is compensated by a mutation in the S4 segment. J Physiol (1997) 1.32

Pressure dependence of the potassium currents of squid giant axon. J Membr Biol (1982) 1.31

Inhibition of human ether à go-go potassium channels by Ca(2+)/calmodulin. EMBO J (2000) 1.27

Molecular cloning and functional expression of a human peptide methionine sulfoxide reductase (hMsrA). FEBS Lett (1999) 1.26

Non-stationary fluctuations of the potassium conductance at the node of ranvier of the frog. J Physiol (1984) 1.25

Unilateral exposure of Shaker B potassium channels to hyperosmolar solutions. Biophys J (1995) 1.25

Generating diversity at GABAergic synapses. Trends Neurosci (2001) 1.24

kappa-Conotoxin PVIIA is a peptide inhibiting the shaker K+ channel. J Biol Chem (1998) 1.23

Identification of ether à go-go and calcium-activated potassium channels in human melanoma cells. J Membr Biol (1999) 1.23

Calcium dependence and distribution of calcium-activated chloride channels in Xenopus oocytes. J Physiol (1997) 1.23

Modulation of cloned skeletal muscle sodium channels by the scorpion toxins Lqh II, Lqh III, and Lqh alphaIT. Pflugers Arch (2000) 1.22

Transmembrane channels based on tartaric acid-gramicidin A hybrids. Science (1989) 1.22

Molecular basis of altered excitability in Shaker mutants of Drosophila melanogaster. EMBO J (1990) 1.22

GAT-1, a high-affinity GABA plasma membrane transporter, is localized to neurons and astroglia in the cerebral cortex. J Neurosci (1995) 1.21

Mechanism of block of single protopores of the Torpedo chloride channel ClC-0 by 2-(p-chlorophenoxy)butyric acid (CPB). J Gen Physiol (2001) 1.18

Functional role of the slow activation property of ERG K+ channels. Eur J Neurosci (1999) 1.18

The role of the IsK protein in the specific pharmacological properties of the IKs channel complex. Br J Pharmacol (1997) 1.16