Published in J Membr Biol on June 01, 2005
Overexpression of Eag1 potassium channels in clinical tumours. Mol Cancer (2006) 1.78
Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics. Genes Dev (2012) 1.64
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Eag1 expression interferes with hypoxia homeostasis and induces angiogenesis in tumors. J Biol Chem (2008) 1.41
Transient receptor potential melastatin 7-like current in human head and neck carcinoma cells: role in cell proliferation. Cancer Res (2007) 1.35
Membrane potential and cancer progression. Front Physiol (2013) 1.35
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Role of Kir4.1 channels in growth control of glia. Glia (2007) 1.09
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Expression profiling of ion channel genes predicts clinical outcome in breast cancer. Mol Cancer (2013) 1.03
MicroRNA-34a inhibits human osteosarcoma proliferation by downregulating ether à go-go 1 expression. Int J Med Sci (2013) 1.03
Transmembrane voltage potential is an essential cellular parameter for the detection and control of tumor development in a Xenopus model. Dis Model Mech (2013) 1.02
The Eag potassium channel as a new prognostic marker in ovarian cancer. Diagn Pathol (2010) 1.00
State-dependent block of HERG potassium channels by R-roscovitine: implications for cancer therapy. Am J Physiol Cell Physiol (2009) 1.00
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DNA hypermethylation of tumors from non-small cell lung cancer (NSCLC) patients is associated with gender and histologic type. Lung Cancer (2009) 0.94
The role of Eag and HERG channels in cell proliferation and apoptotic cell death in SK-OV-3 ovarian cancer cell line. Cancer Cell Int (2011) 0.92
Inhibition of HERG1 K+ channel protein expression decreases cell proliferation of human small cell lung cancer cells. Pflugers Arch (2011) 0.92
Novel Actions of Nonsteroidal Anti-Inflammatory Drugs on Vascular Ion Channels: Accounting for Cardiovascular Side Effects and Identifying New Therapeutic Applications. Mol Cell Pharmacol (2010) 0.91
Flavonoid regulation of EAG1 channels. J Gen Physiol (2013) 0.90
Expression and prognostic roles of Eag1 in resected esophageal squamous cell carcinomas. Dig Dis Sci (2007) 0.90
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Short Hairpin RNA (shRNA) Ether à go-go 1 (Eag1) inhibition of human osteosarcoma angiogenesis via VEGF/PI3K/AKT signaling. Int J Mol Sci (2012) 0.89
Tumor cell-selective apoptosis induction through targeting of K(V)10.1 via bifunctional TRAIL antibody. Mol Cancer (2011) 0.88
Potassium channel activation inhibits proliferation of breast cancer cells by activating a senescence program. Cell Death Dis (2013) 0.88
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Rapid internalization of the oncogenic K+ channel K(V)10.1. PLoS One (2011) 0.84
Human cytomegalovirus inhibition by cardiac glycosides: evidence for involvement of the HERG gene. Antimicrob Agents Chemother (2012) 0.84
Dendrotoxin-κ suppresses tumor growth induced by human lung adenocarcinoma A549 cells in nude mice. J Vet Sci (2011) 0.83
Ceramide modulates HERG potassium channel gating by translocation into lipid rafts. Am J Physiol Cell Physiol (2010) 0.83
Noradrenaline stimulates cell proliferation by suppressing potassium channels via G(i/o) -protein-coupled α(1B) -adrenoceptors in human osteoblasts. Br J Pharmacol (2013) 0.81
Potassium channels in articular chondrocytes. Channels (Austin) (2012) 0.81
Polycomb-dependent repression of the potassium channel-encoding gene KCNA5 promotes cancer cell survival under conditions of stress. Oncogene (2014) 0.81
Genome-wide analysis reveals conserved transcriptional responses downstream of resting potential change in Xenopus embryos, axolotl regeneration, and human mesenchymal cell differentiation. Regeneration (Oxf) (2015) 0.80
The intermediate conductance Ca2+-activated K+ channel inhibitor TRAM-34 stimulates proliferation of breast cancer cells via activation of oestrogen receptors. Br J Pharmacol (2009) 0.79
A novel dendritic nanocarrier of polyamidoamine-polyethylene glycol-cyclic RGD for "smart" small interfering RNA delivery and in vitro antitumor effects by human ether-à-go-go-related gene silencing in anaplastic thyroid carcinoma cells. Int J Nanomedicine (2013) 0.78
Neuronal and Cardiovascular Potassium Channels as Therapeutic Drug Targets: Promise and Pitfalls. J Biomol Screen (2015) 0.77
Long-term channel block is required to inhibit cellular transformation by human ether-à-go-go-related gene (hERG1) potassium channels. Mol Pharmacol (2014) 0.77
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Eag1 channels as potential early-stage biomarkers of hepatocellular carcinoma. Biologics (2016) 0.75
Potassium channel ether à go-go1 is aberrantly expressed in human liposarcoma and promotes tumorigenesis. Biomed Res Int (2014) 0.75
Role of transient receptor potential melastatin type 7 channel in gastric cancer. Integr Med Res (2016) 0.75
Differential regulation of human Eag1 channel expression by serum and epidermal growth factor in lung and breast cancer cells. Onco Targets Ther (2015) 0.75
Impact of NPR-A expression in gastric cancer cells. Int J Clin Exp Med (2014) 0.75
Crystal structure of the PAS domain of the hEAG potassium channel. Acta Crystallogr F Struct Biol Commun (2016) 0.75
Silencing of Eag1 Gene Inhibits Osteosarcoma Proliferation and Migration by Targeting STAT3-VEGF Pathway. Biomed Res Int (2015) 0.75
A three ion channel genes-based signature predicts prognosis of primary glioblastoma patients and reveals a chemotherapy sensitive subtype. Oncotarget (2016) 0.75
Zinc transporters and dysregulated channels in cancers. Front Biosci (Landmark Ed) (2017) 0.75
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herg1 gene and HERG1 protein are overexpressed in colorectal cancers and regulate cell invasion of tumor cells. Cancer Res (2004) 1.49
HERG potassium channels are constitutively expressed in primary human acute myeloid leukemias and regulate cell proliferation of normal and leukemic hemopoietic progenitors. Leukemia (2002) 1.47
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