Published in Mov Disord on December 27, 2013
Regulation of human MAPT gene expression. Mol Neurodegener (2015) 0.90
Epigenetic regulation in Parkinson's disease. Acta Neuropathol (2016) 0.83
Role of the Long Non-Coding RNA MAPT-AS1 in Regulation of Microtubule Associated Protein Tau (MAPT) Expression in Parkinson's Disease. PLoS One (2016) 0.79
Gene expression, methylation and neuropathology correlations at progressive supranuclear palsy risk loci. Acta Neuropathol (2016) 0.77
Is Dysregulation of the HPA-Axis a Core Pathophysiology Mediating Co-Morbid Depression in Neurodegenerative Diseases? Front Psychiatry (2015) 0.77
The Role of MAPT Haplotype H2 and Isoform 1N/4R in Parkinsonism of Older Adults. PLoS One (2016) 0.75
Age-related epigenetic regulation in the brain and its role in neuronal diseases. BMB Rep (2016) 0.75
The Role of DNA Methylation and Histone Modifications in Neurodegenerative Diseases: A Systematic Review. PLoS One (2016) 0.75
Alternative promoter usage generates novel shorter MAPT mRNA transcripts in Alzheimer's disease and progressive supranuclear palsy brains. Sci Rep (2017) 0.75
Deregulation of α-synuclein in Parkinson's disease: Insight from epigenetic structure and transcriptional regulation of SNCA. Prog Neurobiol (2017) 0.75
Epigenome-wide DNA methylation analysis in siblings and monozygotic twins discordant for sporadic Parkinson's disease revealed different epigenetic patterns in peripheral blood mononuclear cells. Neurogenetics (2016) 0.75
Implications of DNA Methylation in Parkinson's Disease. Front Mol Neurosci (2017) 0.75
Genome-wide association study reveals genetic risk underlying Parkinson's disease. Nat Genet (2009) 10.34
Stages in the development of Parkinson's disease-related pathology. Cell Tissue Res (2004) 7.06
Genomic surveys by methylation-sensitive SNP analysis identify sequence-dependent allele-specific DNA methylation. Nat Genet (2008) 5.66
Genomewide association study for susceptibility genes contributing to familial Parkinson disease. Hum Genet (2008) 5.04
Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease. Ann Hum Genet (2010) 4.26
The relationship of DNA methylation with age, gender and genotype in twins and healthy controls. PLoS One (2009) 3.41
Allelic skewing of DNA methylation is widespread across the genome. Am J Hum Genet (2010) 3.17
DNA methylation directs a time-dependent repression of transcription initiation. Curr Biol (1997) 2.83
Functional analysis of promoter CpG methylation using a CpG-free luciferase reporter vector. Epigenetics (2006) 2.68
Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria. Lancet Neurol (2009) 2.60
Linkage disequilibrium fine mapping and haplotype association analysis of the tau gene in progressive supranuclear palsy and corticobasal degeneration. J Med Genet (2005) 2.56
Haplotypes and gene expression implicate the MAPT region for Parkinson disease: the GenePD Study. Neurology (2008) 2.16
GSK3B polymorphisms alter transcription and splicing in Parkinson's disease. Ann Neurol (2005) 2.14
Linkage disequilibrium and association of MAPT H1 in Parkinson disease. Am J Hum Genet (2004) 2.10
The genetic epidemiology of neurodegenerative disease. J Clin Invest (2005) 2.08
Allele-specific DNA methylation in mouse strains is mainly determined by cis-acting sequences. Genome Res (2009) 1.80
Glycogen synthase kinase-3beta and tau genes interact in Alzheimer's disease. Ann Neurol (2008) 1.74
Tau haplotypes regulate transcription and are associated with Parkinson's disease. Ann Neurol (2004) 1.61
MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies. Hum Mol Genet (2012) 1.58
The genetics and neuropathology of Parkinson's disease. Acta Neuropathol (2012) 1.56
Methylation regulates alpha-synuclein expression and is decreased in Parkinson's disease patients' brains. J Neurosci (2010) 1.51
Epigenetic differences in cortical neurons from a pair of monozygotic twins discordant for Alzheimer's disease. PLoS One (2009) 1.49
CpG demethylation enhances alpha-synuclein expression and affects the pathogenesis of Parkinson's disease. PLoS One (2010) 1.34
The Sydney Memory and Ageing Study (MAS): methodology and baseline medical and neuropsychiatric characteristics of an elderly epidemiological non-demented cohort of Australians aged 70-90 years. Int Psychogeriatr (2010) 1.32
Epigenetics: molecular mechanisms and implications for disease. Trends Mol Med (2009) 1.31
Significant association between the tau gene A0/A0 genotype and Parkinson's disease. Ann Neurol (2000) 1.22
Intake of vitamin E, vitamin C, and carotenoids and the risk of Parkinson's disease: a meta-analysis. Lancet Neurol (2005) 1.20
Nutrition and neurodegeneration: epidemiological evidence and challenges for future research. Br J Clin Pharmacol (2013) 1.15
Tau reduction does not prevent motor deficits in two mouse models of Parkinson's disease. PLoS One (2011) 1.10
Rapid and quantitative method of allele-specific DNA methylation analysis. Biotechniques (2006) 1.08
DNA methylation of Alzheimer disease and tauopathy-related genes in postmortem brain. J Neuropathol Exp Neurol (2009) 1.05
The effect of age and the H1c MAPT haplotype on MAPT expression in human brain. Neurobiol Aging (2008) 1.04
Role of epigenetics in Alzheimer's and Parkinson's disease. Epigenomics (2010) 0.98
Functional MAPT haplotypes: bridging the gap between genotype and neuropathology. Neurobiol Dis (2007) 0.98
Gene-environment interactions in Parkinson's disease: specific evidence in humans and mammalian models. Neurobiol Dis (2012) 0.94
Promoter DNA methylation regulates progranulin expression and is altered in FTLD. Acta Neuropathol Commun (2013) 0.90
Genomic imprinting and cancer; new paradigms in the genetics of neoplasia. Toxicol Lett (2001) 0.86
Decrease of methionine and S-adenosylmethionine and increase of homocysteine in treated patients with Parkinson's disease. Neurosci Lett (2001) 0.85
The methylation status of cytosines in a tau gene promoter region alters with age to downregulate transcriptional activity in human cerebral cortex. Neurosci Lett (1999) 0.83
Vitamin and antioxidant rich diet increases MLH1 promoter DNA methylation in DMT2 subjects. Clin Epigenetics (2012) 0.79
Global prevalence of dementia: a Delphi consensus study. Lancet (2005) 23.30
Mild cognitive impairment. Lancet (2006) 10.21
The Sydney multicenter study of Parkinson's disease: the inevitability of dementia at 20 years. Mov Disord (2008) 5.72
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nat Genet (2010) 5.52
Clinicopathological correlates in frontotemporal dementia. Ann Neurol (2004) 4.38
Collaborative analysis of alpha-synuclein gene promoter variability and Parkinson disease. JAMA (2006) 4.26
A DNA vaccine induces SARS coronavirus neutralization and protective immunity in mice. Nature (2004) 3.90
Association of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case-control study. Lancet Neurol (2011) 3.36
pH-dependent entry of severe acute respiratory syndrome coronavirus is mediated by the spike glycoprotein and enhanced by dendritic cell transfer through DC-SIGN. J Virol (2004) 3.04
The pathological basis of semantic dementia. Brain (2005) 2.96
Haemolysis during sample preparation alters microRNA content of plasma. PLoS One (2011) 2.92
Reduced glucocerebrosidase is associated with increased α-synuclein in sporadic Parkinson's disease. Brain (2014) 2.74
Spider silk fibers spun from soluble recombinant silk produced in mammalian cells. Science (2002) 2.69
Heterologous envelope immunogens contribute to AIDS vaccine protection in rhesus monkeys. J Virol (2004) 2.63
Replication-defective adenovirus serotype 5 vectors elicit durable cellular and humoral immune responses in nonhuman primates. J Virol (2005) 2.61
Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria. Lancet Neurol (2009) 2.60
Nonpharmacological therapies in Alzheimer's disease: a systematic review of efficacy. Dement Geriatr Cogn Disord (2010) 2.49
Multiclade human immunodeficiency virus type 1 envelope immunogens elicit broad cellular and humoral immunity in rhesus monkeys. J Virol (2005) 2.40
Caring for Aged Dementia Care Resident Study (CADRES) of person-centred care, dementia-care mapping, and usual care in dementia: a cluster-randomised trial. Lancet Neurol (2009) 2.38
Pedigree with frontotemporal lobar degeneration--motor neuron disease and Tar DNA binding protein-43 positive neuropathology: genetic linkage to chromosome 9. BMC Neurol (2008) 2.34
FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration. Acta Neuropathol (2010) 2.30
Neuropathologic correlates of white matter hyperintensities. Neurology (2008) 2.29
Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's disease in the European population. Hum Mol Genet (2010) 2.21
Large-scale replication and heterogeneity in Parkinson disease genetic loci. Neurology (2012) 2.18
GSK3B polymorphisms alter transcription and splicing in Parkinson's disease. Ann Neurol (2005) 2.14
Mutations in SLC20A2 are a major cause of familial idiopathic basal ganglia calcification. Neurogenetics (2013) 2.11
A comprehensive analysis of prognostic signatures reveals the high predictive capacity of the proliferation, immune response and RNA splicing modules in breast cancer. Breast Cancer Res (2008) 2.09
Disease duration and the integrity of the nigrostriatal system in Parkinson's disease. Brain (2013) 2.09
Immunogenicity of multiple gene and clade human immunodeficiency virus type 1 DNA vaccines. J Virol (2003) 2.09
Determinants of disparities between perceived and physiological risk of falling among elderly people: cohort study. BMJ (2010) 2.02
Increased risk of cognitive impairment in patients with diabetes is associated with metformin. Diabetes Care (2013) 1.99
A multifactorial approach to understanding fall risk in older people. J Am Geriatr Soc (2010) 1.97
Lack of replication of thirteen single-nucleotide polymorphisms implicated in Parkinson's disease: a large-scale international study. Lancet Neurol (2006) 1.92
Diffusion tensor imaging in mild cognitive impairment and Alzheimer's disease: a review. Curr Opin Neurol (2008) 1.92
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data. Brain Imaging Behav (2014) 1.90
Targeted cardiac overexpression of A20 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction. Circulation (2007) 1.88
Management of agitation and aggression associated with Alzheimer disease. Nat Rev Neurol (2009) 1.86
A three-country randomized controlled trial of a psychosocial intervention for caregivers combined with pharmacological treatment for patients with Alzheimer disease: effects on caregiver depression. Am J Geriatr Psychiatry (2008) 1.81
An international consensus study of neuroleptic malignant syndrome diagnostic criteria using the Delphi method. J Clin Psychiatry (2011) 1.80
Multiple biological pathways link cognitive lifestyle to protection from dementia. Biol Psychiatry (2011) 1.79
Neutralizing antibodies elicited by immunization of monkeys with DNA plasmids and recombinant adenoviral vectors expressing human immunodeficiency virus type 1 proteins. J Virol (2005) 1.78
Glycogen synthase kinase-3beta and tau genes interact in Alzheimer's disease. Ann Neurol (2008) 1.74
Analysis of the human VPS13 gene family. Genomics (2004) 1.65
Prescribing of smoking cessation medication in England since the introduction of varenicline. Addiction (2011) 1.65
Prevalence, incidence, and risk factors of lacunar infarcts in a community sample. Neurology (2009) 1.64
Time to redefine PD? Introductory statement of the MDS Task Force on the definition of Parkinson's disease. Mov Disord (2014) 1.63
Cognitive, extrapyramidal, and magnetic resonance imaging predictors of functional impairment in nondemented older community dwellers: the Sydney Older Person Study. J Am Geriatr Soc (2006) 1.63
Multifidus muscle changes and clinical effects of one-level posterior lumbar interbody fusion: minimally invasive procedure versus conventional open approach. Eur Spine J (2009) 1.62
Discrete neuroanatomical networks are associated with specific cognitive abilities in old age. J Neurosci (2011) 1.61
Tau haplotypes regulate transcription and are associated with Parkinson's disease. Ann Neurol (2004) 1.61
Lifespan mental activity predicts diminished rate of hippocampal atrophy. PLoS One (2008) 1.59
AutismKB: an evidence-based knowledgebase of autism genetics. Nucleic Acids Res (2011) 1.59
Disease-specific, neurosphere-derived cells as models for brain disorders. Dis Model Mech (2010) 1.57
A possible role for humoral immunity in the pathogenesis of Parkinson's disease. Brain (2005) 1.57
Small-vessel disease in patients with Parkinson's disease: a clinicopathological study. Mov Disord (2012) 1.56
Recombinant human butyrylcholinesterase from milk of transgenic animals to protect against organophosphate poisoning. Proc Natl Acad Sci U S A (2007) 1.54
UCHL1 is a Parkinson's disease susceptibility gene. Ann Neurol (2004) 1.54
The brain-derived neurotrophic factor Val66Met polymorphism predicts response to exposure therapy in posttraumatic stress disorder. Biol Psychiatry (2013) 1.54
Variance of gene expression identifies altered network constraints in neurological disease. PLoS Genet (2011) 1.53
Abnormalities of the fornix in mild cognitive impairment are related to episodic memory loss. J Alzheimers Dis (2012) 1.52
Neuropsychiatric symptoms in Alzheimer's disease: past progress and anticipation of the future. Alzheimers Dement (2013) 1.51
Can data from primary care medical records be used to monitor national smoking prevalence? J Epidemiol Community Health (2011) 1.50
A piggyBac transposon-based genome-wide library of insertionally mutated Blm-deficient murine ES cells. Genome Res (2009) 1.48
The Falls Efficacy Scale International (FES-I). A comprehensive longitudinal validation study. Age Ageing (2010) 1.48
Progression in frontotemporal dementia: identifying a benign behavioral variant by magnetic resonance imaging. Arch Neurol (2006) 1.47
A systematic review of different models of home and community care services for older persons. BMC Health Serv Res (2011) 1.46
Progression of white matter hyperintensities in elderly individuals over 3 years. Neurology (2007) 1.44
The effect of risperidone on nursing burden associated with caring for patients with dementia. J Am Geriatr Soc (2004) 1.44
Variability in neuronal expression of dopamine receptors and transporters in the substantia nigra. Mov Disord (2013) 1.44
C9ORF72 repeat expansion in clinical and neuropathologic frontotemporal dementia cohorts. Neurology (2012) 1.44
The neglect of somatoform disorders by old age psychiatry: some explanations and suggestions for future research. Int J Geriatr Psychiatry (2003) 1.43
P25alpha immunoreactive but alpha-synuclein immunonegative neuronal inclusions in multiple system atrophy. Acta Neuropathol (2006) 1.43
Mutations in progranulin explain atypical phenotypes with variants in MAPT. Brain (2006) 1.43
Magnetic resonance spectroscopy in cognitive research. Brain Res Brain Res Rev (2004) 1.42
Prevalence and predictors of “subjective cognitive complaints” in the Sydney Memory and Ageing Study. Am J Geriatr Psychiatry (2010) 1.41
Enhanced mucosal immunoglobulin A response of intranasal adenoviral vector human immunodeficiency virus vaccine and localization in the central nervous system. J Virol (2003) 1.41
Grey matter atrophy of basal forebrain and hippocampus in mild cognitive impairment. J Neurol Neurosurg Psychiatry (2010) 1.41