Published in Tissue Eng Part C Methods on January 04, 2014
Enhancing chondrogenic phenotype for cartilage tissue engineering: monoculture and coculture of articular chondrocytes and mesenchymal stem cells. Tissue Eng Part B Rev (2014) 0.90
Articular chondrocytes and mesenchymal stem cells seeded on biodegradable scaffolds for the repair of cartilage in a rat osteochondral defect model. Biomaterials (2014) 0.86
Chondrogenic phenotype of articular chondrocytes in monoculture and co-culture with mesenchymal stem cells in flow perfusion. Tissue Eng Part A (2014) 0.78
Fibroblast growth factor 18 increases the trophic effects of bone marrow mesenchymal stem cells on chondrocytes isolated from late stage osteoarthritic patients. Stem Cells Int (2014) 0.77
Co-culture of chondrons and mesenchymal stromal cells reduces the loss of collagen VI and improves extracellular matrix production. Histochem Cell Biol (2017) 0.75
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods (2001) 414.27
Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue. Biochim Biophys Acta (1986) 13.69
Determination of hydroxyproline. Clin Chim Acta (1967) 7.28
Chondrogenic differentiation and functional maturation of bovine mesenchymal stem cells in long-term agarose culture. Osteoarthritis Cartilage (2005) 3.47
Articular cartilage and osteoarthritis. Instr Course Lect (2005) 2.39
Unlike bone, cartilage regeneration remains elusive. Science (2012) 1.90
Specific growth factors during the expansion and redifferentiation of adult human articular chondrocytes enhance chondrogenesis and cartilaginous tissue formation in vitro. J Cell Biochem (2001) 1.86
Molecular markers predictive of the capacity of expanded human articular chondrocytes to form stable cartilage in vivo. Arthritis Rheum (2001) 1.71
Trophic effects of mesenchymal stem cells increase chondrocyte proliferation and matrix formation. Tissue Eng Part A (2011) 1.50
Articular cartilage engineering with autologous chondrocyte transplantation. A review of recent developments. J Bone Joint Surg Am (2003) 1.44
Calcification or dedifferentiation: requirement to lock mesenchymal stem cells in a desired differentiation stage. J Cell Physiol (2009) 1.42
Failure of in vitro-differentiated mesenchymal stem cells from the synovial membrane to form ectopic stable cartilage in vivo. Arthritis Rheum (2004) 1.34
Micromass co-culture of human articular chondrocytes and human bone marrow mesenchymal stem cells to investigate stable neocartilage tissue formation in vitro. Eur Cell Mater (2010) 1.29
Tissue engineering of functional articular cartilage: the current status. Cell Tissue Res (2011) 1.29
Clinical cartilage restoration: evolution and overview. Clin Orthop Relat Res (2011) 1.28
Trophic effects of mesenchymal stem cells in chondrocyte co-cultures are independent of culture conditions and cell sources. Tissue Eng Part A (2012) 1.27
Enhanced chondrocyte proliferation and mesenchymal stromal cells chondrogenesis in coculture pellets mediate improved cartilage formation. J Cell Physiol (2012) 1.21
Enhanced chondrogenesis in co-cultures with articular chondrocytes and mesenchymal stem cells. Biomaterials (2012) 1.17
Donor site morbidity after articular cartilage repair procedures: a review. Acta Orthop Belg (2010) 1.14
Immunophenotypic changes of human articular chondrocytes during monolayer culture reflect bona fide dedifferentiation rather than amplification of progenitor cells. J Cell Physiol (2008) 1.13
Passaged adult chondrocytes can form engineered cartilage with functional mechanical properties: a canine model. Tissue Eng Part A (2010) 1.12
Chondrocytes or adult stem cells for cartilage repair: the indisputable role of growth factors. Injury (2011) 1.11
Structured three-dimensional co-culture of mesenchymal stem cells with chondrocytes promotes chondrogenic differentiation without hypertrophy. Osteoarthritis Cartilage (2011) 1.10
The effect of hypoxia on the chondrogenic differentiation of co-cultured articular chondrocytes and mesenchymal stem cells in scaffolds. Biomaterials (2013) 1.10
Gene expression and cell differentiation in matrix-associated chondrocyte transplantation grafts: a comparative study. Osteoarthritis Cartilage (2011) 1.03
Population doublings and percentage of S100-positive cells as predictors of in vitro chondrogenicity of expanded human articular chondrocytes. J Cell Physiol (2010) 1.02
Oxygen tension differentially regulates the functional properties of cartilaginous tissues engineered from infrapatellar fat pad derived MSCs and articular chondrocytes. Osteoarthritis Cartilage (2010) 1.00
Nutrient gradients in engineered cartilage: metabolic kinetics measurement and mass transfer modeling. Biotechnol Bioeng (2008) 0.97
Extracellular matrix deposited by synovium-derived stem cells delays replicative senescent chondrocyte dedifferentiation and enhances redifferentiation. J Cell Physiol (2012) 0.96
The interplay between chondrocyte redifferentiation pellet size and oxygen concentration. PLoS One (2013) 0.96
TGF-β3-induced chondrogenesis in co-cultures of chondrocytes and mesenchymal stem cells on biodegradable scaffolds. Biomaterials (2013) 0.95
Chronic exposure of bone morphogenetic protein-2 favors chondrogenic expression in human articular chondrocytes amplified in monolayer cultures. J Cell Biochem (2010) 0.94
Effects of oxygen and culture system on in vitro propagation and redifferentiation of osteoarthritic human articular chondrocytes. Cell Tissue Res (2011) 0.94
Cell sources for articular cartilage repair strategies: shifting from monocultures to cocultures. Tissue Eng Part B Rev (2012) 0.93
Culture of primary bovine chondrocytes on a continuously expanding surface inhibits dedifferentiation. Tissue Eng Part A (2012) 0.92
Cartilage graft engineering by co-culturing primary human articular chondrocytes with human bone marrow stromal cells. J Tissue Eng Regen Med (2012) 0.91
Multiplication of human chondrocytes with low seeding densities accelerates cell yield without losing redifferentiation capacity. Tissue Eng (2004) 0.91
Heterogeneous proliferation within engineered cartilaginous tissue: the role of oxygen tension. Biotechnol Bioeng (2005) 0.90
Integrin-mediated mechanotransduction processes in TGFbeta-stimulated monolayer-expanded chondrocytes. Biochem Biophys Res Commun (2004) 0.89
Secretion of matrix metalloproteinase 3 by expanded articular chondrocytes as a predictor of ectopic cartilage formation capacity in vivo. Arthritis Rheum (2008) 0.88
The dependence of autologous chondrocyte transplantation on varying cellular passage, yield and culture duration. Biomaterials (2011) 0.87
Can one generate stable hyaline cartilage from adult mesenchymal stem cells? A developmental approach. J Tissue Eng Regen Med (2011) 0.85
Low oxygen tension during incubation periods of chondrocyte expansion is sufficient to enhance postexpansion chondrogenesis. Tissue Eng Part A (2010) 0.84
Cartilage-characteristic matrix reconstruction by sequential addition of soluble factors during expansion of human articular chondrocytes and their cultivation in collagen sponges. Tissue Eng Part C Methods (2011) 0.83
Managing the patient with failed cartilage restoration. Sports Med Arthrosc (2013) 0.76
Electrospinning of polymeric nanofibers for tissue engineering applications: a review. Tissue Eng (2006) 4.53
Electrospun poly(epsilon-caprolactone) microfiber and multilayer nanofiber/microfiber scaffolds: characterization of scaffolds and measurement of cellular infiltration. Biomacromolecules (2006) 3.01
Biomimetic materials for tissue engineering. Biomaterials (2003) 2.87
Strategic directions in tissue engineering. Tissue Eng (2007) 2.70
Mineralized matrix deposition by marrow stromal osteoblasts in 3D perfusion culture increases with increasing fluid shear forces. Proc Natl Acad Sci U S A (2003) 2.42
Gelatin as a delivery vehicle for the controlled release of bioactive molecules. J Control Release (2005) 2.32
Thermoresponsive hydrogels in biomedical applications. Eur J Pharm Biopharm (2007) 2.25
Fluid flow increases mineralized matrix deposition in 3D perfusion culture of marrow stromal osteoblasts in a dose-dependent manner. Proc Natl Acad Sci U S A (2002) 2.24
Dual delivery of an angiogenic and an osteogenic growth factor for bone regeneration in a critical size defect model. Bone (2008) 2.19
In vitro generated extracellular matrix and fluid shear stress synergistically enhance 3D osteoblastic differentiation. Proc Natl Acad Sci U S A (2006) 2.03
Donor age and cell passage affects differentiation potential of murine bone marrow-derived stem cells. BMC Cell Biol (2008) 2.00
Injectable matrices and scaffolds for drug delivery in tissue engineering. Adv Drug Deliv Rev (2007) 1.97
Modulation of the inflammatory response for enhanced bone tissue regeneration. Tissue Eng Part B Rev (2008) 1.92
Tissue engineering of bone: material and matrix considerations. J Bone Joint Surg Am (2008) 1.91
Effect of bone extracellular matrix synthesized in vitro on the osteoblastic differentiation of marrow stromal cells. Biomaterials (2005) 1.85
Research Design Considerations. J Grad Med Educ (2016) 1.84
Tissue engineering strategies for bone regeneration. Adv Biochem Eng Biotechnol (2005) 1.80
Design of a flow perfusion bioreactor system for bone tissue-engineering applications. Tissue Eng (2003) 1.79
Injectable biodegradable hydrogel composites for rabbit marrow mesenchymal stem cell and growth factor delivery for cartilage tissue engineering. Biomaterials (2007) 1.78
Dual growth factor delivery from degradable oligo(poly(ethylene glycol) fumarate) hydrogel scaffolds for cartilage tissue engineering. J Control Release (2005) 1.68
Fabrication of porous ultra-short single-walled carbon nanotube nanocomposite scaffolds for bone tissue engineering. Biomaterials (2007) 1.67
Dose effect of dual delivery of vascular endothelial growth factor and bone morphogenetic protein-2 on bone regeneration in a rat critical-size defect model. Tissue Eng Part A (2009) 1.67
Delivery of TGF-beta1 and chondrocytes via injectable, biodegradable hydrogels for cartilage tissue engineering applications. Biomaterials (2005) 1.63
Flow perfusion culture induces the osteoblastic differentiation of marrow stroma cell-scaffold constructs in the absence of dexamethasone. J Biomed Mater Res A (2005) 1.61
Injectable biomaterials for regenerating complex craniofacial tissues. Adv Mater (2009) 1.60
Use of stereolithography to manufacture critical-sized 3D biodegradable scaffolds for bone ingrowth. J Biomed Mater Res B Appl Biomater (2003) 1.59
Osteochondral repair in the rabbit model utilizing bilayered, degradable oligo(poly(ethylene glycol) fumarate) hydrogel scaffolds. J Biomed Mater Res A (2005) 1.58
Strategies for controlled delivery of growth factors and cells for bone regeneration. Adv Drug Deliv Rev (2012) 1.57
Nucleation-dependent polymerization is an essential component of amyloid-mediated neuronal cell death. J Neurosci (2005) 1.56
Engineering complex tissues. Sci Transl Med (2012) 1.54
Polo-like kinase 2 (PLK2) phosphorylates alpha-synuclein at serine 129 in central nervous system. J Biol Chem (2008) 1.54
Photocrosslinking characteristics and mechanical properties of diethyl fumarate/poly(propylene fumarate) biomaterials. Biomaterials (2002) 1.52
In vitro release of transforming growth factor-beta 1 from gelatin microparticles encapsulated in biodegradable, injectable oligo(poly(ethylene glycol) fumarate) hydrogels. J Control Release (2003) 1.52
Nanobiomaterial applications in orthopedics. J Orthop Res (2007) 1.51
Evaluation of bone regeneration using the rat critical size calvarial defect. Nat Protoc (2012) 1.51
Effect of initial cell seeding density on early osteogenic signal expression of rat bone marrow stromal cells cultured on cross-linked poly(propylene fumarate) disks. Biomacromolecules (2009) 1.48
Bioactive poly(L-lactic acid) conduits seeded with Schwann cells for peripheral nerve regeneration. Biomaterials (2002) 1.47
Formation of three-dimensional cell/polymer constructs for bone tissue engineering in a spinner flask and a rotating wall vessel bioreactor. J Biomed Mater Res (2002) 1.46
Transforming growth factor-beta 1 release from oligo(poly(ethylene glycol) fumarate) hydrogels in conditions that model the cartilage wound healing environment. J Control Release (2004) 1.45
Thermally cross-linked oligo(poly(ethylene glycol) fumarate) hydrogels support osteogenic differentiation of encapsulated marrow stromal cells in vitro. Biomacromolecules (2004) 1.45
Biodegradable gelatin microparticles as delivery systems for the controlled release of bone morphogenetic protein-2. Acta Biomater (2008) 1.43
Osteogenic differentiation of mesenchymal stem cells on pregenerated extracellular matrix scaffolds in the absence of osteogenic cell culture supplements. Tissue Eng Part A (2010) 1.38
Harnessing and modulating inflammation in strategies for bone regeneration. Tissue Eng Part B Rev (2011) 1.37
In vivo biocompatibility of ultra-short single-walled carbon nanotube/biodegradable polymer nanocomposites for bone tissue engineering. Bone (2008) 1.35
Review: mineralization of synthetic polymer scaffolds for bone tissue engineering. Tissue Eng (2007) 1.35
Effect of poly(ethylene glycol) molecular weight on tensile and swelling properties of oligo(poly(ethylene glycol) fumarate) hydrogels for cartilage tissue engineering. J Biomed Mater Res (2002) 1.34
Pre-culture period of mesenchymal stem cells in osteogenic media influences their in vivo bone forming potential. J Biomed Mater Res A (2007) 1.34
In vitro osteogenic differentiation of marrow stromal cells encapsulated in biodegradable hydrogels. J Biomed Mater Res A (2004) 1.32
Soft and hard tissue response to photocrosslinked poly(propylene fumarate) scaffolds in a rabbit model. J Biomed Mater Res (2002) 1.31
Kinetics of poly(propylene fumarate) synthesis by step polymerization of diethyl fumarate and propylene glycol using zinc chloride as a catalyst. J Biomater Sci Polym Ed (2002) 1.30
Interphase molecular cytogenetic screening for chromosomal abnormalities of prognostic significance in childhood acute lymphoblastic leukaemia: a UK Cancer Cytogenetics Group Study. Br J Haematol (2005) 1.29
Flow perfusion enhances the calcified matrix deposition of marrow stromal cells in biodegradable nonwoven fiber mesh scaffolds. Ann Biomed Eng (2005) 1.29
In vitro cytotoxicity of injectable and biodegradable poly(propylene fumarate)-based networks: unreacted macromers, cross-linked networks, and degradation products. Biomacromolecules (2003) 1.29
The influence of an in vitro generated bone-like extracellular matrix on osteoblastic gene expression of marrow stromal cells. Biomaterials (2008) 1.29
A cellular model for sporadic ALS using patient-derived induced pluripotent stem cells. Mol Cell Neurosci (2013) 1.25
Modeling Ewing sarcoma tumors in vitro with 3D scaffolds. Proc Natl Acad Sci U S A (2013) 1.23
Influence of the porosity of starch-based fiber mesh scaffolds on the proliferation and osteogenic differentiation of bone marrow stromal cells cultured in a flow perfusion bioreactor. Tissue Eng (2006) 1.23
Injectable nanocomposites of single-walled carbon nanotubes and biodegradable polymers for bone tissue engineering. Biomacromolecules (2006) 1.23
Modulation of differentiation and mineralization of marrow stromal cells cultured on biomimetic hydrogels modified with Arg-Gly-Asp containing peptides. J Biomed Mater Res A (2004) 1.22
Modulation of marrow stromal osteoblast adhesion on biomimetic oligo[poly(ethylene glycol) fumarate] hydrogels modified with Arg-Gly-Asp peptides and a poly(ethyleneglycol) spacer. J Biomed Mater Res (2002) 1.22
In vitro and in vivo release of vascular endothelial growth factor from gelatin microparticles and biodegradable composite scaffolds. Pharm Res (2008) 1.21
Angiogenesis with biomaterial-based drug- and cell-delivery systems. J Biomater Sci Polym Ed (2004) 1.21
Modulation of osteogenic properties of biodegradable polymer/extracellular matrix scaffolds generated with a flow perfusion bioreactor. Acta Biomater (2010) 1.21
Repair of osteochondral defects with biodegradable hydrogel composites encapsulating marrow mesenchymal stem cells in a rabbit model. Acta Biomater (2009) 1.21
Synthesis of poly(propylene fumarate). Nat Protoc (2009) 1.20
Effect of flow perfusion on the osteogenic differentiation of bone marrow stromal cells cultured on starch-based three-dimensional scaffolds. J Biomed Mater Res A (2003) 1.20
In vivo bone and soft tissue response to injectable, biodegradable oligo(poly(ethylene glycol) fumarate) hydrogels. Biomaterials (2003) 1.19
Engineering tumors: a tissue engineering perspective in cancer biology. Tissue Eng Part B Rev (2010) 1.19
Effect of dual growth factor delivery on chondrogenic differentiation of rabbit marrow mesenchymal stem cells encapsulated in injectable hydrogel composites. J Biomed Mater Res A (2009) 1.18
Synthesis and characterization of injectable, thermally and chemically gelable, amphiphilic poly(N-isopropylacrylamide)-based macromers. Biomacromolecules (2008) 1.18
Effect of swelling ratio of injectable hydrogel composites on chondrogenic differentiation of encapsulated rabbit marrow mesenchymal stem cells in vitro. Biomacromolecules (2009) 1.18
Osteogenic differentiation of rat bone marrow stromal cells cultured on Arg-Gly-Asp modified hydrogels without dexamethasone and beta-glycerol phosphate. Biomaterials (2005) 1.17
Enhanced chondrogenesis in co-cultures with articular chondrocytes and mesenchymal stem cells. Biomaterials (2012) 1.17
Bioactive polymer/extracellular matrix scaffolds fabricated with a flow perfusion bioreactor for cartilage tissue engineering. Biomaterials (2010) 1.16
In vitro localization of bone growth factors in constructs of biodegradable scaffolds seeded with marrow stromal cells and cultured in a flow perfusion bioreactor. Tissue Eng (2006) 1.15
In vitro generation of an osteochondral construct using injectable hydrogel composites encapsulating rabbit marrow mesenchymal stem cells. Biomaterials (2009) 1.13
Attachment, proliferation, and migration of marrow stromal osteoblasts cultured on biomimetic hydrogels modified with an osteopontin-derived peptide. Biomaterials (2004) 1.13
Uncultured marrow mononuclear cells delivered within fibrin glue hydrogels to porous scaffolds enhance bone regeneration within critical-sized rat cranial defects. Tissue Eng Part A (2010) 1.12
In humans, early cortisol biosynthesis provides a mechanism to safeguard female sexual development. J Clin Invest (2006) 1.12
Repair of osteochondral defects with hyaluronan- and polyester-based scaffolds. Osteoarthritis Cartilage (2005) 1.11
In vitro degradation of polymeric networks of poly(propylene fumarate) and the crosslinking macromer poly(propylene fumarate)-diacrylate. Biomaterials (2003) 1.11
Two-dimensional nanostructure-reinforced biodegradable polymeric nanocomposites for bone tissue engineering. Biomacromolecules (2013) 1.11
The effect of hypoxia on the chondrogenic differentiation of co-cultured articular chondrocytes and mesenchymal stem cells in scaffolds. Biomaterials (2013) 1.10