Published in J Bacteriol on January 24, 2014
Core principles of bacterial autoinducer systems. Microbiol Mol Biol Rev (2015) 0.94
CdiA promotes receptor-independent intercellular adhesion. Mol Microbiol (2015) 0.93
Contact-Dependent Growth Inhibition (CDI) and CdiB/CdiA Two-Partner Secretion Proteins. J Mol Biol (2015) 0.87
Bacterial quorum sensing and metabolic slowing in a cooperative population. Proc Natl Acad Sci U S A (2014) 0.86
Interbacterial signaling via Burkholderia contact-dependent growth inhibition system proteins. Proc Natl Acad Sci U S A (2016) 0.86
Genome-Wide RNA Sequencing Analysis of Quorum Sensing-Controlled Regulons in the Plant-Associated Burkholderia glumae PG1 Strain. Appl Environ Microbiol (2015) 0.80
A Burkholderia thailandensis Acyl-Homoserine Lactone-Independent Orphan LuxR Homolog That Activates Production of the Cytotoxin Malleilactone. J Bacteriol (2015) 0.80
Cross-species comparison of the Burkholderia pseudomallei, Burkholderia thailandensis, and Burkholderia mallei quorum-sensing regulons. J Bacteriol (2014) 0.78
Quorum sensing control of Type VI secretion factors restricts the proliferation of quorum-sensing mutants. Elife (2016) 0.76
Quorum Sensing Influences Burkholderia thailandensis Biofilm Development and Matrix Production. J Bacteriol (2016) 0.76
Discovery of scmR as a global regulator of secondary metabolism and virulence in Burkholderia thailandensis E264. Proc Natl Acad Sci U S A (2017) 0.76
Quorum Sensing in a Methane-Oxidizing Bacterium. J Bacteriol (2017) 0.75
Lethal Consequences of Overcoming Metabolic Restrictions Imposed on a Cooperative Bacterial Population. MBio (2017) 0.75
Insights into the Quorum Sensing Regulon of the Acidophilic Acidithiobacillus ferrooxidans Revealed by Transcriptomic in the Presence of an Acyl Homoserine Lactone Superagonist Analog. Front Microbiol (2016) 0.75
Nice or nasty: Protein translocation between bacteria and the different forms of response. Proc Natl Acad Sci U S A (2016) 0.75
Interplay between 4-Hydroxy-3-Methyl-2-Alkylquinoline and N-Acyl-Homoserine Lactone Signaling in a Burkholderia cepacia Complex Clinical Strain. Front Microbiol (2017) 0.75
Basic local alignment search tool. J Mol Biol (1990) 659.07
Census and consensus in bacterial ecosystems: the LuxR-LuxI family of quorum-sensing transcriptional regulators. Annu Rev Microbiol (1996) 10.26
Identification, timing, and signal specificity of Pseudomonas aeruginosa quorum-controlled genes: a transcriptome analysis. J Bacteriol (2003) 8.11
Quorum sensing and Chromobacterium violaceum: exploitation of violacein production and inhibition for the detection of N-acylhomoserine lactones. Microbiology (1997) 7.83
Roles of Pseudomonas aeruginosa las and rhl quorum-sensing systems in control of elastase and rhamnolipid biosynthesis genes. J Bacteriol (1997) 7.51
Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei. Proc Natl Acad Sci U S A (2004) 7.30
Regulatory sequence analysis tools. Nucleic Acids Res (2003) 5.72
DNAPlotter: circular and linear interactive genome visualization. Bioinformatics (2008) 5.49
Burkholderia thailandensis sp. nov., a Burkholderia pseudomallei-like species. Int J Syst Bacteriol (1998) 5.34
Multiple homologues of LuxR and LuxI control expression of virulence determinants and secondary metabolites through quorum sensing in Pseudomonas aeruginosa PAO1. Mol Microbiol (1995) 5.12
Isolation and characterization of a regulatory gene affecting rhamnolipid biosurfactant synthesis in Pseudomonas aeruginosa. J Bacteriol (1994) 5.03
Autoinducer-mediated regulation of rhamnolipid biosurfactant synthesis in Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (1995) 5.03
A Tn7-based broad-range bacterial cloning and expression system. Nat Methods (2005) 4.66
Structural flexibility in the Burkholderia mallei genome. Proc Natl Acad Sci U S A (2004) 4.13
Pseudomonas aeruginosa LasA: a second elastase under the transcriptional control of lasR. Mol Microbiol (1991) 3.73
Digital transcriptome profiling using selective hexamer priming for cDNA synthesis. Nat Methods (2009) 3.73
N-(3-oxohexanoyl)-L-homoserine lactone regulates carbapenem antibiotic production in Erwinia carotovora. Biochem J (1992) 3.40
The cep quorum-sensing system of Burkholderia cepacia H111 controls biofilm formation and swarming motility. Microbiology (2001) 3.37
A network of networks: quorum-sensing gene regulation in Pseudomonas aeruginosa. Int J Med Microbiol (2006) 3.26
mini-Tn7 insertion in bacteria with single attTn7 sites: example Pseudomonas aeruginosa. Nat Protoc (2006) 3.19
Arabinose assimilation defines a nonvirulent biotype of Burkholderia pseudomallei. Infect Immun (1997) 2.72
Phenazine antibiotic biosynthesis in Pseudomonas aureofaciens 30-84 is regulated by PhzR in response to cell density. J Bacteriol (1994) 2.62
The chain of command in Pseudomonas quorum sensing. Trends Microbiol (1997) 2.56
Genomic patterns of pathogen evolution revealed by comparison of Burkholderia pseudomallei, the causative agent of melioidosis, to avirulent Burkholderia thailandensis. BMC Microbiol (2006) 2.35
Carbapenem antibiotic production in Erwinia carotovora is regulated by CarR, a homologue of the LuxR transcriptional activator. Microbiology (1995) 1.98
Ecology of Burkholderia pseudomallei and the interactions between environmental Burkholderia spp. and human-animal hosts. Acta Trop (2000) 1.91
Genomic islands from five strains of Burkholderia pseudomallei. BMC Genomics (2008) 1.82
Quorum-sensing and siderophore biosynthesis in Pseudomonas aeruginosa: lasR/lasI mutants exhibit reduced pyoverdine biosynthesis. FEMS Microbiol Lett (1998) 1.74
A hierarchical quorum-sensing system in Yersinia pseudotuberculosis is involved in the regulation of motility and clumping. Mol Microbiol (1999) 1.69
Burkholderia thailandensis as a model system for the study of the virulence-associated type III secretion system of Burkholderia pseudomallei. Infect Immun (2008) 1.52
Role of quorum sensing in the pathogenicity of Burkholderia pseudomallei. J Med Microbiol (2004) 1.47
The Burkholderia bcpAIOB genes define unique classes of two-partner secretion and contact dependent growth inhibition systems. PLoS Genet (2012) 1.44
Chitinolytic activity in Chromobacterium violaceum: substrate analysis and regulation by quorum sensing. J Bacteriol (1998) 1.43
Targeted mutagenesis of Burkholderia thailandensis and Burkholderia pseudomallei through natural transformation of PCR fragments. Appl Environ Microbiol (2008) 1.41
The toxin/immunity network of Burkholderia pseudomallei contact-dependent growth inhibition (CDI) systems. Mol Microbiol (2012) 1.41
The PmlI-PmlR quorum-sensing system in Burkholderia pseudomallei plays a key role in virulence and modulates production of the MprA protease. J Bacteriol (2004) 1.41
Burkholderia thailandensis E125 harbors a temperate bacteriophage specific for Burkholderia mallei. J Bacteriol (2002) 1.36
A second quorum-sensing system regulates cell surface properties but not phenazine antibiotic production in Pseudomonas aureofaciens. Appl Environ Microbiol (2001) 1.34
Quorum-sensing control of antibiotic synthesis in Burkholderia thailandensis. J Bacteriol (2009) 1.33
Mutational analysis of Burkholderia thailandensis quorum sensing and self-aggregation. J Bacteriol (2009) 1.28
Comparative genomics and an insect model rapidly identify novel virulence genes of Burkholderia mallei. J Bacteriol (2008) 1.27
The BpsIR quorum-sensing system of Burkholderia pseudomallei. J Bacteriol (2005) 1.27
PGAT: a multistrain analysis resource for microbial genomes. Bioinformatics (2011) 1.26
Quorum sensing: a transcriptional regulatory system involved in the pathogenicity of Burkholderia mallei. Infect Immun (2004) 1.22
Bacterial quorum sensing, cooperativity, and anticipation of stationary-phase stress. Proc Natl Acad Sci U S A (2012) 1.22
Inhalation of Burkholderia thailandensis results in lethal necrotizing pneumonia in mice: a surrogate model for pneumonic melioidosis. Trans R Soc Trop Med Hyg (2008) 1.20
Quorum-sensing-dependent regulation of biosynthesis of the polyketide antibiotic mupirocin in Pseudomonas fluorescens NCIMB 10586. Microbiology (2001) 1.17
Mutational analysis and biochemical characterization of the Burkholderia thailandensis DW503 quorum-sensing network. J Bacteriol (2004) 1.15
Quorum quenching: enzymatic disruption of N-acylhomoserine lactone-mediated bacterial communication in Burkholderia thailandensis. Appl Environ Microbiol (2004) 1.14
Characterization of Pseudomonas aeruginosa chitinase, a gradually secreted protein. J Bacteriol (2001) 1.10
Why genes evolve faster on secondary chromosomes in bacteria. PLoS Comput Biol (2010) 1.10
Strain-dependent diversity in the Pseudomonas aeruginosa quorum-sensing regulon. Proc Natl Acad Sci U S A (2012) 1.09
Burkholderia BcpA mediates biofilm formation independently of interbacterial contact-dependent growth inhibition. Mol Microbiol (2013) 1.09
Quorum-sensing-regulated bactobolin production by Burkholderia thailandensis E264. Org Lett (2010) 1.08
Reciprocal regulation by the CepIR and CciIR quorum sensing systems in Burkholderia cenocepacia. BMC Genomics (2009) 1.08
Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions. Appl Environ Microbiol (2009) 1.06
Octanoyl-homoserine lactone is the cognate signal for Burkholderia mallei BmaR1-BmaI1 quorum sensing. J Bacteriol (2007) 1.05
Genetic and phenotypic diversity in Burkholderia: contributions by prophage and phage-like elements. BMC Microbiol (2010) 1.02
Polysaccharides and virulence of Burkholderia pseudomallei. J Med Microbiol (2007) 1.00
Malleilactone, a polyketide synthase-derived virulence factor encoded by the cryptic secondary metabolome of Burkholderia pseudomallei group pathogens. J Am Chem Soc (2012) 0.98
Dictyostelium discoideum as a model system for identification of Burkholderia pseudomallei virulence factors. Infect Immun (2011) 0.98
Functional interplay between the Yersinia pseudotuberculosis YpsRI and YtbRI quorum sensing systems modulates swimming motility by controlling expression of flhDC and fliA. Mol Microbiol (2008) 0.93
Carbapenem antibiotic biosynthesis in Erwinia carotovora is regulated by physiological and genetic factors modulating the quorum sensing-dependent control pathway. Mol Microbiol (2005) 0.90
Common patterns and unique features of P-type ATPases: a comparative view on the KdpFABC complex from Escherichia coli (Review). Mol Membr Biol (2007) 0.87
Quorum-sensing signal synthesis by the Yersinia pestis acyl-homoserine lactone synthase YspI. J Bacteriol (2006) 0.86
Virulence of Burkholderia mallei quorum-sensing mutants. Infect Immun (2013) 0.86
Burkholderia thailandensis is virulent in Drosophila melanogaster. PLoS One (2012) 0.83
Characterization of the type III capsular polysaccharide produced by Burkholderia pseudomallei. J Med Microbiol (2010) 0.78
Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays. Science (2003) 16.80
Listening in on bacteria: acyl-homoserine lactone signalling. Nat Rev Mol Cell Biol (2002) 6.01
Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. Cell (2004) 4.91
A component of innate immunity prevents bacterial biofilm development. Nature (2002) 4.73
Adult chronic rhinosinusitis: definitions, diagnosis, epidemiology, and pathophysiology. Otolaryngol Head Neck Surg (2003) 4.63
Quorum sensing in Staphylococcus aureus biofilms. J Bacteriol (2004) 3.58
A comprehensive transposon mutant library of Francisella novicida, a bioweapon surrogate. Proc Natl Acad Sci U S A (2007) 3.49
Microbial sciences: the superficial life of microbes. Nature (2006) 3.45
A network of networks: quorum-sensing gene regulation in Pseudomonas aeruginosa. Int J Med Microbiol (2006) 3.26
Iron and Pseudomonas aeruginosa biofilm formation. Proc Natl Acad Sci U S A (2005) 3.26
Growth phenotypes of Pseudomonas aeruginosa lasR mutants adapted to the airways of cystic fibrosis patients. Mol Microbiol (2007) 2.87
Chelator-induced dispersal and killing of Pseudomonas aeruginosa cells in a biofilm. Appl Environ Microbiol (2006) 2.72
Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains. Genome Biol (2007) 2.68
Activity of purified QscR, a Pseudomonas aeruginosa orphan quorum-sensing transcription factor. Mol Microbiol (2006) 2.38
Dengue virus inhibits alpha interferon signaling by reducing STAT2 expression. J Virol (2005) 2.37
The Vibrio fischeri quorum-sensing systems ain and lux sequentially induce luminescence gene expression and are important for persistence in the squid host. Mol Microbiol (2003) 2.35
A comprehensive transcript index of the human genome generated using microarrays and computational approaches. Genome Biol (2004) 2.21
A widespread bacterial type VI secretion effector superfamily identified using a heuristic approach. Cell Host Microbe (2012) 2.08
Analysis of the genome of the Escherichia coli O157:H7 2006 spinach-associated outbreak isolate indicates candidate genes that may enhance virulence. Infect Immun (2009) 2.07
Genetic determinants of self identity and social recognition in bacteria. Science (2008) 2.07
Novel Pseudomonas aeruginosa quorum-sensing inhibitors identified in an ultra-high-throughput screen. Antimicrob Agents Chemother (2006) 2.04
Acyl-homoserine lactone quorum sensing: from evolution to application. Annu Rev Microbiol (2013) 1.98
Temporal analysis of early immune responses in patients with acute hepatitis B virus infection. Gastroenterology (2009) 1.88
Dengue virus NS5 inhibits interferon-alpha signaling by blocking signal transducer and activator of transcription 2 phosphorylation. J Infect Dis (2009) 1.83
Bacterial quorum sensing and metabolic incentives to cooperate. Science (2012) 1.82
Pathogenesis of flavivirus infections: using and abusing the host cell. Cell Host Microbe (2009) 1.81
Unique signatures of long noncoding RNA expression in response to virus infection and altered innate immune signaling. MBio (2010) 1.79
The single-nucleotide resolution transcriptome of Pseudomonas aeruginosa grown in body temperature. PLoS Pathog (2012) 1.72
A distinct QscR regulon in the Pseudomonas aeruginosa quorum-sensing circuit. J Bacteriol (2006) 1.69
Genome mosaicism is conserved but not unique in Pseudomonas aeruginosa isolates from the airways of young children with cystic fibrosis. Environ Microbiol (2003) 1.68
Expression of alternatively spliced sodium channel alpha-subunit genes. Unique splicing patterns are observed in dorsal root ganglia. J Biol Chem (2004) 1.67
Optimization of oligonucleotide arrays and RNA amplification protocols for analysis of transcript structure and alternative splicing. Genome Biol (2003) 1.66
Salmonella effectors translocated across the vacuolar membrane interact with the actin cytoskeleton. Mol Microbiol (2003) 1.55
Potential source of Francisella tularensis live vaccine strain attenuation determined by genome comparison. Infect Immun (2006) 1.55
Global position analysis of the Pseudomonas aeruginosa quorum-sensing transcription factor LasR. Mol Microbiol (2009) 1.55
The genetic basis for the commitment to chronic versus acute infection in Pseudomonas aeruginosa. Mol Cell (2004) 1.54
A structurally unrelated mimic of a Pseudomonas aeruginosa acyl-homoserine lactone quorum-sensing signal. Proc Natl Acad Sci U S A (2006) 1.54
Acute lung injury and other serious complications of Plasmodium vivax malaria. Lancet Infect Dis (2008) 1.52
Vibrio parahaemolyticus ScrC modulates cyclic dimeric GMP regulation of gene expression relevant to growth on surfaces. J Bacteriol (2007) 1.48
A complex interplay among virus, dendritic cells, T cells, and cytokines in dengue virus infections. J Immunol (2008) 1.48
Tetracycline-inducible packaging cell line for production of flavivirus replicon particles. J Virol (2004) 1.44
The value of intraoperative ultrasound during hepatic resection compared with improved preoperative magnetic resonance imaging. Eur J Ultrasound (2003) 1.43
Unique integration profiles in a canine model of long-term repopulating cells transduced with gammaretrovirus, lentivirus, or foamy virus. Hum Gene Ther (2007) 1.42
Digital genome-wide ncRNA expression, including SnoRNAs, across 11 human tissues using polyA-neutral amplification. PLoS One (2010) 1.42
DNA copy number, including telomeres and mitochondria, assayed using next-generation sequencing. BMC Genomics (2010) 1.41
Vancomycin-resistant enterococci infection: not just for the transplanted. Leuk Lymphoma (2013) 1.39
Transcriptome analysis of the Vibrio fischeri LuxR-LuxI regulon. J Bacteriol (2007) 1.34
Early activation of quorum sensing in Pseudomonas aeruginosa reveals the architecture of a complex regulon. BMC Genomics (2007) 1.33
Quorum-sensing control of antibiotic synthesis in Burkholderia thailandensis. J Bacteriol (2009) 1.33
Adoption of a clinical pharmacogenomics implementation program during outpatient care--initial results of the University of Chicago "1,200 Patients Project". Am J Med Genet C Semin Med Genet (2014) 1.30
Mutational analysis of Burkholderia thailandensis quorum sensing and self-aggregation. J Bacteriol (2009) 1.28
Influence of quorum sensing and iron on twitching motility and biofilm formation in Pseudomonas aeruginosa. J Bacteriol (2007) 1.24
Generation of virulence factor variants in Staphylococcus aureus biofilms. J Bacteriol (2007) 1.24
Bacterial quorum sensing, cooperativity, and anticipation of stationary-phase stress. Proc Natl Acad Sci U S A (2012) 1.22
Acyl-homoserine lactone-dependent eavesdropping promotes competition in a laboratory co-culture model. ISME J (2012) 1.21
Disruption of platelet-derived chemokine heteromers prevents neutrophil extravasation in acute lung injury. Am J Respir Crit Care Med (2012) 1.18
Clinical and virological study of dengue cases and the members of their households: the multinational DENFRAME Project. PLoS Negl Trop Dis (2012) 1.17
Isovaleryl-homoserine lactone, an unusual branched-chain quorum-sensing signal from the soybean symbiont Bradyrhizobium japonicum. Proc Natl Acad Sci U S A (2011) 1.17
Clinical Management of Ebola Virus Disease in the United States and Europe. N Engl J Med (2016) 1.15
Aryl-homoserine lactone quorum sensing in stem-nodulating photosynthetic bradyrhizobia. Proc Natl Acad Sci U S A (2011) 1.12
Increase in rhamnolipid synthesis under iron-limiting conditions influences surface motility and biofilm formation in Pseudomonas aeruginosa. J Bacteriol (2010) 1.10
Strain-dependent diversity in the Pseudomonas aeruginosa quorum-sensing regulon. Proc Natl Acad Sci U S A (2012) 1.09
A mutational analysis defines Vibrio fischeri LuxR binding sites. J Bacteriol (2007) 1.09
Simvastatin reduces endotoxin-induced acute lung injury by decreasing neutrophil recruitment and radical formation. PLoS One (2012) 1.08
Quorum-sensing-regulated bactobolin production by Burkholderia thailandensis E264. Org Lett (2010) 1.08
Delays in Pseudomonas aeruginosa quorum-controlled gene expression are conditional. Proc Natl Acad Sci U S A (2005) 1.08
Role of flagella in virulence of the coral pathogen Vibrio coralliilyticus. Appl Environ Microbiol (2009) 1.07
The Burkholderia mallei BmaR3-BmaI3 quorum-sensing system produces and responds to N-3-hydroxy-octanoyl homoserine lactone. J Bacteriol (2008) 1.06
Genetic validation of whole-transcriptome sequencing for mapping expression affected by cis-regulatory variation. BMC Genomics (2010) 1.06
Use of phage display to identify potential Pseudomonas aeruginosa gene products relevant to early cystic fibrosis airway infections. Infect Immun (2005) 1.06
Octanoyl-homoserine lactone is the cognate signal for Burkholderia mallei BmaR1-BmaI1 quorum sensing. J Bacteriol (2007) 1.05
NSR-seq transcriptional profiling enables identification of a gene signature of Plasmodium falciparum parasites infecting children. J Clin Invest (2011) 1.04
Acyl-homoserine lactone binding to and stability of the orphan Pseudomonas aeruginosa quorum-sensing signal receptor QscR. J Bacteriol (2010) 1.04
Identification of a new dengue virus inhibitor that targets the viral NS4B protein and restricts genomic RNA replication. Antiviral Res (2013) 1.03
Activity of the Rhodopseudomonas palustris p-coumaroyl-homoserine lactone-responsive transcription factor RpaR. J Bacteriol (2011) 1.03
Synthetic ligands that activate and inhibit a quorum-sensing regulator in Pseudomonas aeruginosa. Bioorg Med Chem Lett (2007) 1.03
Enhancement of antimicrobial activity against pseudomonas aeruginosa by coadministration of G10KHc and tobramycin. Antimicrob Agents Chemother (2006) 1.03
A derivate of the antibiotic doxorubicin is a selective inhibitor of dengue and yellow fever virus replication in vitro. Antimicrob Agents Chemother (2010) 1.02
GWAS analyzer: integrating genotype, phenotype and public annotation data for genome-wide association study analysis. Bioinformatics (2010) 1.02
Hypoxia induces dilated cardiomyopathy in the chick embryo: mechanism, intervention, and long-term consequences. PLoS One (2009) 1.02
Sequence-verified two-allele transposon mutant library for Pseudomonas aeruginosa PAO1. J Bacteriol (2012) 1.02
Deciphering diatom biochemical pathways via whole-cell proteomics. Aquat Microb Ecol (2009) 0.98
The Pseudomonas aeruginosa proteome during anaerobic growth. J Bacteriol (2005) 0.98
In vivo and in vitro activity of the siderophore monosulfactam BAL30072 against Acinetobacter baumannii. J Antimicrob Chemother (2011) 0.98
Sources of diversity in bactobolin biosynthesis by Burkholderia thailandensis E264. Org Lett (2011) 0.97
Identification, structure, and function of a novel type VI secretion peptidoglycan glycoside hydrolase effector-immunity pair. J Biol Chem (2013) 0.97
Anaerobic p-coumarate degradation by Rhodopseudomonas palustris and identification of CouR, a MarR repressor protein that binds p-coumaroyl coenzyme A. J Bacteriol (2012) 0.95
Training a sophisticated microsurgical technique: interposition of external jugular vein graft in the common carotid artery in rats. J Vis Exp (2012) 0.95
Identity gene expression in Proteus mirabilis. J Bacteriol (2011) 0.93
Dengue virus replicon expressing the nonstructural proteins suffices to enhance membrane expression of HLA class I and inhibit lysis by human NK cells. J Virol (2008) 0.93
The diversity and management of chronic hepatitis B virus infections in the United Kingdom: a wake-up call. Clin Infect Dis (2012) 0.92
Effect of nitric oxide and peroxynitrite on type I collagen synthesis in normal and scleroderma dermal fibroblasts. Free Radic Biol Med (2007) 0.91
Reversible signal binding by the Pseudomonas aeruginosa quorum-sensing signal receptor LasR. MBio (2011) 0.91
A pangenomic analysis of the Nannochloropsis organellar genomes reveals novel genetic variations in key metabolic genes. BMC Genomics (2014) 0.90
Genotype-phenotype associations in a nonmodel prokaryote. MBio (2012) 0.90
Bactobolin resistance is conferred by mutations in the L2 ribosomal protein. MBio (2012) 0.90
Cell cycle inhibition by sodium arsenite in primary embryonic rat midbrain neuroepithelial cells. Toxicol Sci (2005) 0.89
Cost-effectiveness of peginterferon alpha-2a compared with lamivudine treatment in patients with HBe-antigen-positive chronic hepatitis B in the United Kingdom. Eur J Gastroenterol Hepatol (2007) 0.89