Published in PLoS One on January 22, 2014
Degradation of Cep68 and PCNT cleavage mediate Cep215 removal from the PCM to allow centriole separation, disengagement and licensing. Nat Cell Biol (2014) 1.55
A unique set of centrosome proteins requires pericentrin for spindle-pole localization and spindle orientation. Curr Biol (2014) 1.52
The position of lysosomes within the cell determines their luminal pH. J Cell Biol (2016) 1.13
Centrosome function and assembly in animal cells. Nat Rev Mol Cell Biol (2015) 1.12
A molecular mechanism of mitotic centrosome assembly in Drosophila. Elife (2014) 1.09
Molecular and cellular basis of autosomal recessive primary microcephaly. Biomed Res Int (2014) 0.98
A CEP215-HSET complex links centrosomes with spindle poles and drives centrosome clustering in cancer. Nat Commun (2016) 0.95
Loss of CDK5RAP2 affects neural but not non-neural mESC differentiation into cardiomyocytes. Cell Cycle (2015) 0.84
A mitotic kinase scaffold depleted in testicular seminomas impacts spindle orientation in germ line stem cells. Elife (2015) 0.83
Depletion of pericentrin in mouse oocytes disrupts microtubule organizing center function and meiotic spindle organization. Mol Reprod Dev (2014) 0.81
Interphase centrosome organization by the PLP-Cnn scaffold is required for centrosome function. J Cell Biol (2015) 0.80
The Drosophila Pericentrin-like-protein (PLP) cooperates with Cnn to maintain the integrity of the outer PCM. Biol Open (2015) 0.77
Unique subcellular distribution of phosphorylated Plk1 (Ser137 and Thr210) in mouse oocytes during meiotic division and pPlk1(Ser137) involvement in spindle formation and REC8 cleavage. Cell Cycle (2015) 0.76
PLK1 regulation of PCNT cleavage ensures fidelity of centriole separation during mitotic exit. Nat Commun (2015) 0.75
Journey to the center of the centrosome. Dev Cell (2014) 0.75
The DNA replication protein Cdc6 inhibits the microtubule-organizing activity of the centrosome. J Biol Chem (2017) 0.75
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A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size. Nat Genet (2005) 5.48
Mutations in the pericentrin (PCNT) gene cause primordial dwarfism. Science (2008) 4.04
The PACT domain, a conserved centrosomal targeting motif in the coiled-coil proteins AKAP450 and pericentrin. EMBO Rep (2000) 3.31
GCP-WD is a gamma-tubulin targeting factor required for centrosomal and chromatin-mediated microtubule nucleation. Nat Cell Biol (2005) 3.12
The centrosomin protein is required for centrosome assembly and function during cleavage in Drosophila. Development (1999) 2.78
Mitosis-specific anchoring of gamma tubulin complexes by pericentrin controls spindle organization and mitotic entry. Mol Biol Cell (2004) 2.71
NEDD1-dependent recruitment of the gamma-tubulin ring complex to the centrosome is necessary for centriole duplication and spindle assembly. J Cell Biol (2006) 2.38
Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors. Development (2010) 2.31
Subdiffraction-resolution fluorescence microscopy reveals a domain of the centrosome critical for pericentriolar material organization. Nat Cell Biol (2012) 2.23
Subdiffraction imaging of centrosomes reveals higher-order organizational features of pericentriolar material. Nat Cell Biol (2012) 2.19
Microtubule nucleation at non-spindle pole body microtubule-organizing centers requires fission yeast centrosomin-related protein mod20p. Curr Biol (2004) 2.17
CDK5RAP2 is a pericentriolar protein that functions in centrosomal attachment of the gamma-tubulin ring complex. Mol Biol Cell (2007) 2.13
The homeotic target gene centrosomin encodes an essential centrosomal component. Cell (1996) 1.96
The mammalian SPD-2 ortholog Cep192 regulates centrosome biogenesis. Curr Biol (2008) 1.88
Centrioles regulate centrosome size by controlling the rate of Cnn incorporation into the PCM. Curr Biol (2010) 1.87
Human Cep192 is required for mitotic centrosome and spindle assembly. Curr Biol (2007) 1.81
CDK5RAP2 stimulates microtubule nucleation by the gamma-tubulin ring complex. J Cell Biol (2010) 1.80
Plk1-dependent recruitment of gamma-tubulin complexes to mitotic centrosomes involves multiple PCM components. PLoS One (2009) 1.79
Cep68 and Cep215 (Cdk5rap2) are required for centrosome cohesion. J Cell Sci (2007) 1.78
Identification and characterization of two novel proteins affecting fission yeast gamma-tubulin complex function. Mol Biol Cell (2004) 1.75
CDK5RAP2 regulates centriole engagement and cohesion in mice. Dev Cell (2010) 1.61
Cdk5rap2 interacts with pericentrin to maintain the neural progenitor pool in the developing neocortex. Neuron (2010) 1.60
Maintaining the proper connection between the centrioles and the pericentriolar matrix requires Drosophila centrosomin. J Cell Biol (2007) 1.58
Pericentrin in cellular function and disease. J Cell Biol (2009) 1.46
PLK1 phosphorylation of pericentrin initiates centrosome maturation at the onset of mitosis. J Cell Biol (2011) 1.43
CDK5RAP2 functions in centrosome to spindle pole attachment and DNA damage response. J Cell Biol (2010) 1.43
Inhibition of centrosome protein assembly leads to p53-dependent exit from the cell cycle. J Cell Biol (2006) 1.34
Proper recruitment of gamma-tubulin and D-TACC/Msps to embryonic Drosophila centrosomes requires Centrosomin Motif 1. Mol Biol Cell (2007) 1.33
Conserved motif of CDK5RAP2 mediates its localization to centrosomes and the Golgi complex. J Biol Chem (2010) 1.24
The pericentriolar satellite protein CEP90 is crucial for integrity of the mitotic spindle pole. J Cell Sci (2011) 1.12
Two distinct regions of Mto1 are required for normal microtubule nucleation and efficient association with the gamma-tubulin complex in vivo. J Cell Sci (2008) 1.12
A novel nonsense CDK5RAP2 mutation in a Somali child with primary microcephaly and sensorineural hearing loss. Am J Med Genet A (2012) 1.06
Previously described sequence variant in CDK5RAP2 gene in a Pakistani family with autosomal recessive primary microcephaly. BMC Med Genet (2007) 1.01
CEP215 is involved in the dynein-dependent accumulation of pericentriolar matrix proteins for spindle pole formation. Cell Cycle (2010) 0.98
Integrity of the Pericentriolar Material Is Essential for Maintaining Centriole Association during M Phase. PLoS One (2015) 0.75
BOULE, a Deleted in Azoospermia Homolog, Is Recruited to Stress Granules in the Mouse Male Germ Cells. PLoS One (2016) 0.75
Importance of eIF2α phosphorylation as a protective mechanism against heat stress in mouse male germ cells. Mol Reprod Dev (2017) 0.75