Published in Curr Biol on November 01, 2007
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Overly long centrioles and defective cell division upon excess of the SAS-4-related protein CPAP. Curr Biol (2009) 2.48
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Cep72 regulates the localization of key centrosomal proteins and proper bipolar spindle formation. EMBO J (2009) 1.13
PHD1 links cell-cycle progression to oxygen sensing through hydroxylation of the centrosomal protein Cep192. Dev Cell (2013) 1.12
Centrosome function and assembly in animal cells. Nat Rev Mol Cell Biol (2015) 1.12
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A molecular mechanism of mitotic centrosome assembly in Drosophila. Elife (2014) 1.09
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Control of mitotic and meiotic centriole duplication by the Plk4-related kinase ZYG-1. J Cell Sci (2010) 0.97
The Cep192-organized aurora A-Plk1 cascade is essential for centrosome cycle and bipolar spindle assembly. Mol Cell (2014) 0.96
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RBM14 prevents assembly of centriolar protein complexes and maintains mitotic spindle integrity. EMBO J (2014) 0.89
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Cep192 controls the balance of centrosome and non-centrosomal microtubules during interphase. PLoS One (2014) 0.82
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A potential role for NEDD1 and the centrosome in senescence of mouse embryonic fibroblasts. Cell Death Dis (2010) 0.82
Decoding ubiquitin for mitosis. Genes Cancer (2012) 0.82
PIPKIγ targets to the centrosome and restrains centriole duplication. J Cell Sci (2014) 0.81
Depletion of pericentrin in mouse oocytes disrupts microtubule organizing center function and meiotic spindle organization. Mol Reprod Dev (2014) 0.81
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Exploring the evolutionary history of centrosomes. Philos Trans R Soc Lond B Biol Sci (2014) 0.80
Interphase centrosome organization by the PLP-Cnn scaffold is required for centrosome function. J Cell Biol (2015) 0.80
Cross-Talk between AURKA and Plk1 in Mitotic Entry and Spindle Assembly. Front Oncol (2015) 0.77
Unique subcellular distribution of phosphorylated Plk1 (Ser137 and Thr210) in mouse oocytes during meiotic division and pPlk1(Ser137) involvement in spindle formation and REC8 cleavage. Cell Cycle (2015) 0.76
Targeting of Fzr/Cdh1 for timely activation of the APC/C at the centrosome during mitotic exit. Nat Commun (2016) 0.76
Bimodal Interaction of Mammalian Polo-Like Kinase 1 and a Centrosomal Scaffold, Cep192, in the Regulation of Bipolar Spindle Formation. Mol Cell Biol (2015) 0.76
Structural Basis for Mitotic Centrosome Assembly in Flies. Cell (2017) 0.75
AIBp regulates mitotic entry and mitotic spindle assembly by controlling activation of both Aurora-A and Plk1. Cell Cycle (2015) 0.75
PCM1 Depletion Inhibits Glioblastoma Cell Ciliogenesis and Increases Cell Death and Sensitivity to Temozolomide. Transl Oncol (2016) 0.75
Polo-like kinase phosphorylation determines Caenorhabditis elegans centrosome size and density by biasing SPD-5 toward an assembly-competent conformation. Biol Open (2016) 0.75
The DNA replication protein Cdc6 inhibits the microtubule-organizing activity of the centrosome. J Biol Chem (2017) 0.75
The Zebrafish curly fry Is Required for Proper Centrosome and Mitotic Spindle Assembly. Zebrafish (2017) 0.75
NEK7 is required for G1 progression and procentriole formation. Mol Biol Cell (2017) 0.75
Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication. Cell (2008) 8.41
Minimizing the risk of reporting false positives in large-scale RNAi screens. Nat Methods (2006) 5.96
Human host factors required for influenza virus replication. Nature (2010) 5.28
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen. Proc Natl Acad Sci U S A (2008) 4.80
Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase. Nature (2003) 4.63
Drosophila EB1 is important for proper assembly, dynamics, and positioning of the mitotic spindle. J Cell Biol (2002) 4.40
Host cell factors in HIV replication: meta-analysis of genome-wide studies. PLoS Pathog (2009) 4.24
Global landscape of HIV-human protein complexes. Nature (2011) 3.70
Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization. Mol Cell Biol (2004) 3.62
Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling. PLoS One (2008) 3.59
Inflammation after trauma: microglial activation and traumatic brain injury. Ann Neurol (2011) 3.42
A probability-based approach for the analysis of large-scale RNAi screens. Nat Methods (2007) 3.34
The role of the posterior cingulate cortex in cognition and disease. Brain (2013) 2.98
Endocardial cells form the coronary arteries by angiogenesis through myocardial-endocardial VEGF signaling. Cell (2012) 2.71
Fractionating the default mode network: distinct contributions of the ventral and dorsal posterior cingulate cortex to cognitive control. J Neurosci (2011) 2.65
A human MAP kinase interactome. Nat Methods (2010) 2.62
Default mode network connectivity predicts sustained attention deficits after traumatic brain injury. J Neurosci (2011) 2.57
An efficient rapid system for profiling the cellular activities of molecular libraries. Proc Natl Acad Sci U S A (2006) 2.51
Genome-scale functional profiling of the mammalian AP-1 signaling pathway. Proc Natl Acad Sci U S A (2003) 2.45
Genome-wide functional analysis of human cell-cycle regulators. Proc Natl Acad Sci U S A (2006) 2.31
Echoes of the brain within the posterior cingulate cortex. J Neurosci (2012) 2.24
Functionally distinct kinesin-13 family members cooperate to regulate microtubule dynamics during interphase. Nat Cell Biol (2005) 2.24
Three microtubule severing enzymes contribute to the "Pacman-flux" machinery that moves chromosomes. J Cell Biol (2007) 2.09
HIV integration targeting: a pathway involving Transportin-3 and the nuclear pore protein RanBP2. PLoS Pathog (2011) 2.00
Traumatic brain injury impairs small-world topology. Neurology (2013) 1.94
Lipid G protein-coupled receptor ligand identification using beta-arrestin PathHunter assay. J Biol Chem (2009) 1.91
The structure of the plk4 cryptic polo box reveals two tandem polo boxes required for centriole duplication. Structure (2012) 1.87
Salience network integrity predicts default mode network function after traumatic brain injury. Proc Natl Acad Sci U S A (2012) 1.86
Determining the distribution of probes between different subcellular locations through automated unmixing of subcellular patterns. Proc Natl Acad Sci U S A (2010) 1.82
Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients. Cancer Res (2009) 1.79
Echoes of the brain within default mode, association, and heteromodal cortices. J Neurosci (2013) 1.66
Identification of novel mammalian growth regulatory factors by genome-scale quantitative image analysis. Genome Res (2005) 1.59
Spindle microtubules in flux. J Cell Sci (2005) 1.56
KL1 is a novel microtubule severing enzyme that regulates mitotic spindle architecture. Cell Cycle (2010) 1.54
Identification of p53 regulators by genome-wide functional analysis. Proc Natl Acad Sci U S A (2004) 1.48
Telomere-independent Rap1 is an IKK adaptor and regulates NF-kappaB-dependent gene expression. Nat Cell Biol (2010) 1.47
Poleward tubulin flux in spindles: regulation and function in mitotic cells. Mol Biol Cell (2007) 1.47
Megator, an essential coiled-coil protein that localizes to the putative spindle matrix during mitosis in Drosophila. Mol Biol Cell (2004) 1.47
Whole genome functional analysis identifies novel components required for mitotic spindle integrity in human cells. Genome Biol (2008) 1.46
Drosophila katanin is a microtubule depolymerase that regulates cortical-microtubule plus-end interactions and cell migration. Nat Cell Biol (2011) 1.45
The chromokinesin, KLP3A, dives mitotic spindle pole separation during prometaphase and anaphase and facilitates chromatid motility. Mol Biol Cell (2003) 1.39
Systematic identification of cellular signals reactivating Kaposi sarcoma-associated herpesvirus. PLoS Pathog (2007) 1.32
Cerebral venous system and anatomical predisposition to high-altitude headache. Ann Neurol (2013) 1.29
Cognitive control and the salience network: an investigation of error processing and effective connectivity. J Neurosci (2013) 1.26
Kinesin-13s form rings around microtubules. J Cell Biol (2006) 1.23
A role for IkappaB kinase 2 in bipolar spindle assembly. Proc Natl Acad Sci U S A (2007) 1.21
Bmi-1 regulation of INK4A-ARF is a downstream requirement for transformation of hematopoietic progenitors by E2a-Pbx1. Mol Cell (2003) 1.20
A functional genomics approach to the mode of action of apratoxin A. Nat Chem Biol (2006) 1.20
Self-similar correlation function in brain resting-state functional magnetic resonance imaging. J R Soc Interface (2010) 1.20
The control of global brain dynamics: opposing actions of frontoparietal control and default mode networks on attention. J Neurosci (2014) 1.18
An RNAi screen identifies TRRAP as a regulator of brain tumor-initiating cell differentiation. Cell Stem Cell (2010) 1.17
The Protein Phosphatase 2A regulatory subunit Twins stabilizes Plk4 to induce centriole amplification. J Cell Biol (2011) 1.16
B cell terminal differentiation factor XBP-1 induces reactivation of Kaposi's sarcoma-associated herpesvirus. FEBS Lett (2007) 1.16
Identification of the tyrosine phosphatase PTP-MEG2 as an antagonist of hepatic insulin signaling. Cell Metab (2006) 1.15
Tumor suppressor protein (p)53, is a regulator of NF-kappaB repression by the glucocorticoid receptor. Proc Natl Acad Sci U S A (2011) 1.14
A short hairpin RNA screen of interferon-stimulated genes identifies a novel negative regulator of the cellular antiviral response. MBio (2013) 1.13
Fulfilling the promise: drug discovery in the post-genomic era. Drug Discov Today (2003) 1.12
A new Augmin subunit, Msd1, demonstrates the importance of mitotic spindle-templated microtubule nucleation in the absence of functioning centrosomes. Genes Dev (2009) 1.12
Identification of the Wnt signaling activator leucine-rich repeat in Flightless interaction protein 2 by a genome-wide functional analysis. Proc Natl Acad Sci U S A (2005) 1.11
In silico gene prioritization by integrating multiple data sources. PLoS One (2011) 1.10
Human Fidgetin is a microtubule severing the enzyme and minus-end depolymerase that regulates mitosis. Cell Cycle (2012) 1.06
The neural basis of impaired self-awareness after traumatic brain injury. Brain (2013) 1.05
Slow axonal transport and the genesis of neuronal morphology. J Neurobiol (2004) 1.05
Drosophila katanin-60 depolymerizes and severs at microtubule defects. Biophys J (2011) 1.04
Identification of novel therapeutic targets for HIV infection through functional genomic cDNA screening. Virology (2007) 1.04
EAST interacts with Megator and localizes to the putative spindle matrix during mitosis in Drosophila. J Cell Biochem (2005) 1.03
The Drosophila kinesin-13, KLP59D, impacts Pacman- and Flux-based chromosome movement. Mol Biol Cell (2009) 1.03
GPS-Prot: a web-based visualization platform for integrating host-pathogen interaction data. BMC Bioinformatics (2011) 1.03
Functional connectivity measures after psilocybin inform a novel hypothesis of early psychosis. Schizophr Bull (2012) 1.03
Identification of homeodomain proteins, PBX1 and PREP1, involved in the transcription of murine leukemia virus. Mol Cell Biol (2003) 1.02
Identifying HIV-1 host cell factors by genome-scale RNAi screening. Methods (2010) 1.00
Enhanced expression of nicotinamide N-methyltransferase in human papillary thyroid carcinoma cells. J Clin Endocrinol Metab (2003) 0.99
Chromator is required for proper microtubule spindle formation and mitosis in Drosophila. Dev Biol (2009) 0.97
Regional changes in thalamic shape and volume with increasing age. Neuroimage (2012) 0.97
Individual prediction of white matter injury following traumatic brain injury. Ann Neurol (2013) 0.96
The promise of genomics to identify novel therapeutic targets. Expert Opin Ther Targets (2004) 0.96
KLP10A and KLP59C: the dynamic duo of microtubule depolymerization. Cell Cycle (2005) 0.96
Polo-like kinase 4 autodestructs by generating its Slimb-binding phosphodegron. Curr Biol (2013) 0.95
A robust method for investigating thalamic white matter tracts after traumatic brain injury. Neuroimage (2012) 0.95
How can investigation of network function inform rehabilitation after traumatic brain injury? Curr Opin Neurol (2012) 0.94
Motor domain phosphorylation and regulation of the Drosophila kinesin 13, KLP10A. J Cell Biol (2009) 0.94
Identification and characterization of a small molecule antagonist of human VPAC(2) receptor. Mol Pharmacol (2009) 0.94