Published in PLoS One on June 19, 2009
Quantitative proteomics combined with BAC TransgeneOmics reveals in vivo protein interactions. J Cell Biol (2010) 3.61
Primary microcephaly: do all roads lead to Rome? Trends Genet (2009) 3.60
3D-structured illumination microscopy provides novel insight into architecture of human centrosomes. Biol Open (2012) 2.23
Subdiffraction imaging of centrosomes reveals higher-order organizational features of pericentriolar material. Nat Cell Biol (2012) 2.19
Structured illumination of the interface between centriole and peri-centriolar material. Open Biol (2012) 2.03
The Plk1-dependent phosphoproteome of the early mitotic spindle. Mol Cell Proteomics (2010) 1.91
Degradation of Cep68 and PCNT cleavage mediate Cep215 removal from the PCM to allow centriole separation, disengagement and licensing. Nat Cell Biol (2014) 1.55
Cdk5rap2 exposes the centrosomal root of microcephaly syndromes. Trends Cell Biol (2011) 1.53
A unique set of centrosome proteins requires pericentrin for spindle-pole localization and spindle orientation. Curr Biol (2014) 1.52
Pericentrin in cellular function and disease. J Cell Biol (2009) 1.46
PLK1 phosphorylation of pericentrin initiates centrosome maturation at the onset of mitosis. J Cell Biol (2011) 1.43
CDK5RAP2 functions in centrosome to spindle pole attachment and DNA damage response. J Cell Biol (2010) 1.43
Breaking the ties that bind: new advances in centrosome biology. J Cell Biol (2012) 1.41
The centrosome-specific phosphorylation of Cnn by Polo/Plk1 drives Cnn scaffold assembly and centrosome maturation. Dev Cell (2014) 1.40
Centrosomes. Regulated assembly of a supramolecular centrosome scaffold in vitro. Science (2015) 1.27
Conserved motif of CDK5RAP2 mediates its localization to centrosomes and the Golgi complex. J Biol Chem (2010) 1.24
The centrosome and its duplication cycle. Cold Spring Harb Perspect Biol (2015) 1.23
Let's huddle to prevent a muddle: centrosome declustering as an attractive anticancer strategy. Cell Death Differ (2012) 1.17
Pericentriolar material structure and dynamics. Philos Trans R Soc Lond B Biol Sci (2014) 1.16
The gammaTuRC revisited: a comparative analysis of interphase and mitotic human gammaTuRC redefines the set of core components and identifies the novel subunit GCP8. Mol Biol Cell (2010) 1.13
Centrosome function and assembly in animal cells. Nat Rev Mol Cell Biol (2015) 1.12
Amorphous no more: subdiffraction view of the pericentriolar material architecture. Trends Cell Biol (2013) 1.10
A molecular mechanism of mitotic centrosome assembly in Drosophila. Elife (2014) 1.09
WD40-repeat protein 62 is a JNK-phosphorylated spindle pole protein required for spindle maintenance and timely mitotic progression. J Cell Sci (2012) 1.05
Importance of the CEP215-pericentrin interaction for centrosome maturation during mitosis. PLoS One (2014) 1.03
The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolus. Nucleic Acids Res (2010) 1.02
Bod1 regulates protein phosphatase 2A at mitotic kinetochores. Nat Commun (2013) 0.97
The Cep192-organized aurora A-Plk1 cascade is essential for centrosome cycle and bipolar spindle assembly. Mol Cell (2014) 0.96
Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancer. Front Oncol (2013) 0.96
The centrosome-Golgi apparatus nexus. Philos Trans R Soc Lond B Biol Sci (2014) 0.95
A CEP215-HSET complex links centrosomes with spindle poles and drives centrosome clustering in cancer. Nat Commun (2016) 0.95
Continuous polo-like kinase 1 activity regulates diffusion to maintain centrosome self-organization during mitosis. Proc Natl Acad Sci U S A (2011) 0.92
p38α MAPK is a MTOC-associated protein regulating spindle assembly, spindle length and accurate chromosome segregation during mouse oocyte meiotic maturation. Cell Cycle (2010) 0.89
Nek2 phosphorylates and stabilizes β-catenin at mitotic centrosomes downstream of Plk1. Mol Biol Cell (2014) 0.89
Plk1 regulates both ASAP localization and its role in spindle pole integrity. J Biol Chem (2010) 0.88
CDK11(p58) is required for centriole duplication and Plk4 recruitment to mitotic centrosomes. PLoS One (2011) 0.88
Excess centrosomes disrupt endothelial cell migration via centrosome scattering. J Cell Biol (2014) 0.88
Nek9 regulates spindle organization and cell cycle progression during mouse oocyte meiosis and its location in early embryo mitosis. Cell Cycle (2012) 0.87
A direct interaction with NEDD1 regulates gamma-tubulin recruitment to the centrosome. PLoS One (2010) 0.86
Drosophila pericentrin requires interaction with calmodulin for its function at centrosomes and neuronal basal bodies but not at sperm basal bodies. Mol Biol Cell (2014) 0.85
Integrins regulate microtubule nucleating activity of centrosome through mitogen-activated protein kinase/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase (MEK/ERK) signaling. J Biol Chem (2011) 0.85
Loss of CDK5RAP2 affects neural but not non-neural mESC differentiation into cardiomyocytes. Cell Cycle (2015) 0.84
The PTEN-Akt pathway impacts the integrity and composition of mitotic centrosomes. Cell Cycle (2013) 0.83
Organelle asymmetry for proper fitness, function, and fate. Chromosome Res (2013) 0.82
Plk1 relieves centriole block to reduplication by promoting daughter centriole maturation. Nat Commun (2015) 0.81
Multiple requirements of PLK1 during mouse oocyte maturation. PLoS One (2015) 0.81
Sensors at centrosomes reveal determinants of local separase activity. PLoS Genet (2014) 0.81
Interphase centrosome organization by the PLP-Cnn scaffold is required for centrosome function. J Cell Biol (2015) 0.80
The function of mammalian Polo-like kinase 1 in microtubule nucleation. Proc Natl Acad Sci U S A (2011) 0.79
Quantitative immunofluorescence assay to measure the variation in protein levels at centrosomes. J Vis Exp (2014) 0.78
Characterization of Adenomatous Polyposis Coli Protein Dynamics and Localization at the Centrosome. Cancers (Basel) (2016) 0.77
The Drosophila Pericentrin-like-protein (PLP) cooperates with Cnn to maintain the integrity of the outer PCM. Biol Open (2015) 0.77
Cross-Talk between AURKA and Plk1 in Mitotic Entry and Spindle Assembly. Front Oncol (2015) 0.77
Interaction of CK1δ with γTuSC ensures proper microtubule assembly and spindle positioning. Mol Biol Cell (2015) 0.77
Coiled-coil domain containing protein 124 is a novel centrosome and midbody protein that interacts with the Ras-guanine nucleotide exchange factor 1B and is involved in cytokinesis. PLoS One (2013) 0.77
Bimodal Interaction of Mammalian Polo-Like Kinase 1 and a Centrosomal Scaffold, Cep192, in the Regulation of Bipolar Spindle Formation. Mol Cell Biol (2015) 0.76
Unique subcellular distribution of phosphorylated Plk1 (Ser137 and Thr210) in mouse oocytes during meiotic division and pPlk1(Ser137) involvement in spindle formation and REC8 cleavage. Cell Cycle (2015) 0.76
Structural Basis for Mitotic Centrosome Assembly in Flies. Cell (2017) 0.75
Centrosome - a promising anti-cancer target. Biologics (2016) 0.75
Plk1 inhibition leads to a failure of mitotic division during the first mitotic division in pig embryos. J Assist Reprod Genet (2017) 0.75
MLL5 maintains spindle bipolarity by preventing aberrant cytosolic aggregation of PLK1. J Cell Biol (2016) 0.75
Polo-like kinase phosphorylation determines Caenorhabditis elegans centrosome size and density by biasing SPD-5 toward an assembly-competent conformation. Biol Open (2016) 0.75
Recent advances in pericentriolar material organization: ordered layers and scaffolding gels. F1000Res (2017) 0.75
Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen. Science (1999) 12.52
Polo-like kinases and the orchestration of cell division. Nat Rev Mol Cell Biol (2004) 7.22
The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain. Cell (2003) 7.04
Proteomic screen finds pSer/pThr-binding domain localizing Plk1 to mitotic substrates. Science (2003) 6.97
The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1. Curr Biol (2007) 6.17
Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes. J Cell Biol (1996) 5.17
BI 2536, a potent and selective inhibitor of polo-like kinase 1, inhibits tumor growth in vivo. Curr Biol (2007) 5.17
Pericentrin and gamma-tubulin form a protein complex and are organized into a novel lattice at the centrosome. J Cell Biol (1998) 4.23
Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle. J Cell Biol (2008) 4.10
The sudden recruitment of gamma-tubulin to the centrosome at the onset of mitosis and its dynamic exchange throughout the cell cycle, do not require microtubules. J Cell Biol (1999) 3.42
Roles of polo-like kinase 1 in the assembly of functional mitotic spindles. Curr Biol (2004) 3.29
Microtubule-organizing centres: a re-evaluation. Nat Rev Mol Cell Biol (2007) 3.28
GCP-WD is a gamma-tubulin targeting factor required for centrosomal and chromatin-mediated microtubule nucleation. Nat Cell Biol (2005) 3.12
HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity. Curr Biol (2009) 2.98
Spatial and temporal coordination of mitosis by Ran GTPase. Nat Rev Mol Cell Biol (2008) 2.84
Mitosis-specific anchoring of gamma tubulin complexes by pericentrin controls spindle organization and mitotic entry. Mol Biol Cell (2004) 2.71
Microtubule nucleation: gamma-tubulin and beyond. J Cell Sci (2006) 2.71
A genome-wide RNAi screen to dissect centriole duplication and centrosome maturation in Drosophila. PLoS Biol (2008) 2.43
NEDD1-dependent recruitment of the gamma-tubulin ring complex to the centrosome is necessary for centriole duplication and spindle assembly. J Cell Biol (2006) 2.38
Use of the novel Plk1 inhibitor ZK-thiazolidinone to elucidate functions of Plk1 in early and late stages of mitosis. Mol Biol Cell (2007) 2.38
Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex. Mol Biol Cell (2002) 2.26
Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation. Dev Cell (2003) 2.18
Microtubule nucleation at non-spindle pole body microtubule-organizing centers requires fission yeast centrosomin-related protein mod20p. Curr Biol (2004) 2.17
CDK5RAP2 is a pericentriolar protein that functions in centrosomal attachment of the gamma-tubulin ring complex. Mol Biol Cell (2007) 2.13
The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells. Proc Natl Acad Sci U S A (2009) 1.98
Myomegalin is a novel protein of the golgi/centrosome that interacts with a cyclic nucleotide phosphodiesterase. J Biol Chem (2000) 1.97
The mammalian SPD-2 ortholog Cep192 regulates centrosome biogenesis. Curr Biol (2008) 1.88
Human Cep192 is required for mitotic centrosome and spindle assembly. Curr Biol (2007) 1.81
Cep68 and Cep215 (Cdk5rap2) are required for centrosome cohesion. J Cell Sci (2007) 1.78
Recruitment of antigenic gamma-tubulin during mitosis in animal cells: presence of gamma-tubulin in the mitotic spindle. J Cell Sci (1994) 1.69
Probing cell-division phenotype space and Polo-like kinase function using small molecules. Nat Chem Biol (2006) 1.65
Gamma-tubulin complexes and microtubule organization. Curr Opin Cell Biol (2006) 1.64
Interaction of Aurora-A and centrosomin at the microtubule-nucleating site in Drosophila and mammalian cells. J Cell Biol (2003) 1.58
FAM29A promotes microtubule amplification via recruitment of the NEDD1-gamma-tubulin complex to the mitotic spindle. J Cell Biol (2008) 1.56
Inhibitors of Polo-like kinase reveal roles in spindle-pole maintenance. Nat Chem Biol (2006) 1.47
Coordinate regulation of the mother centriole component nlp by nek2 and plk1 protein kinases. Mol Cell Biol (2005) 1.26
Phosphorylation of Nlp by Plk1 negatively regulates its dynein-dynactin-dependent targeting to the centrosome. J Cell Sci (2005) 1.25
Mechanism limiting centrosome duplication to once per cell cycle. Nature (2006) 4.69
Microtubule-organizing centres: a re-evaluation. Nat Rev Mol Cell Biol (2007) 3.28
The centrosome cycle: Centriole biogenesis, duplication and inherent asymmetries. Nat Cell Biol (2011) 3.17
GCP-WD is a gamma-tubulin targeting factor required for centrosomal and chromatin-mediated microtubule nucleation. Nat Cell Biol (2005) 3.12
Cep152 interacts with Plk4 and is required for centriole duplication. J Cell Biol (2010) 2.45
Centrosome number is controlled by a centrosome-intrinsic block to reduplication. Nat Cell Biol (2003) 2.33
Polo kinase and separase regulate the mitotic licensing of centriole duplication in human cells. Dev Cell (2009) 2.24
Molecular characterization of centriole assembly in ciliated epithelial cells. J Cell Biol (2007) 2.13
Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism. Proc Natl Acad Sci U S A (2007) 2.10
Autophagy promotes primary ciliogenesis by removing OFD1 from centriolar satellites. Nature (2013) 2.07
Controlling centrosome number: licenses and blocks. Curr Opin Cell Biol (2005) 2.00
A crucial requirement for Hedgehog signaling in small cell lung cancer. Nat Med (2011) 1.97
Adenomatous polyposis coli and EB1 localize in close proximity of the mother centriole and EB1 is a functional component of centrosomes. J Cell Sci (2004) 1.83
Mammalian cells lack checkpoints for tetraploidy, aberrant centrosome number, and cytokinesis failure. BMC Cell Biol (2005) 1.75
Centriole age underlies asynchronous primary cilium growth in mammalian cells. Curr Biol (2009) 1.70
Insights into microtubule nucleation from the crystal structure of human gamma-tubulin. Nature (2005) 1.66
The dynamics of microtubule minus ends in the human mitotic spindle. Nat Cell Biol (2014) 1.60
The centriolar satellite proteins Cep72 and Cep290 interact and are required for recruitment of BBS proteins to the cilium. Mol Biol Cell (2012) 1.44
Epsilon-tubulin is required for centriole duplication and microtubule organization. Nat Cell Biol (2003) 1.42
Transcriptional program of ciliated epithelial cells reveals new cilium and centrosome components and links to human disease. PLoS One (2012) 1.32
Supernumerary centrosomes nucleate extra cilia and compromise primary cilium signaling. Curr Biol (2012) 1.31
Cep120 is asymmetrically localized to the daughter centriole and is essential for centriole assembly. J Cell Biol (2010) 1.29
The where, when and how of microtubule nucleation - one ring to rule them all. J Cell Sci (2012) 1.24
CEP120 and SPICE1 cooperate with CPAP in centriole elongation. Curr Biol (2013) 1.22
Myb promotes centriole amplification and later steps of the multiciliogenesis program. Development (2013) 1.17
The gammaTuRC revisited: a comparative analysis of interphase and mitotic human gammaTuRC redefines the set of core components and identifies the novel subunit GCP8. Mol Biol Cell (2010) 1.13
STED microscopy with optimized labeling density reveals 9-fold arrangement of a centriole protein. Biophys J (2012) 1.06
Primary cilia: cellular sensors for the skeleton. Anat Rec (Hoboken) (2008) 1.05
Mechanosensing by the primary cilium: deletion of Kif3A reduces bone formation due to loading. PLoS One (2012) 0.99
Cep63 and cep152 cooperate to ensure centriole duplication. PLoS One (2013) 0.92
gamma-Tubulin. Curr Biol (2002) 0.90
FOP is a centriolar satellite protein involved in ciliogenesis. PLoS One (2013) 0.90
Curcumin inhibits growth of Saccharomyces cerevisiae through iron chelation. Eukaryot Cell (2011) 0.90
STED Super-resolution Microscopy in Drosophila Tissue and in Mammalian Cells. Proc SPIE Int Soc Opt Eng (2011) 0.83
Systematic structure-function analysis of the small GTPase Arf1 in yeast. Mol Biol Cell (2002) 0.81
The Rilp-like proteins Rilpl1 and Rilpl2 regulate ciliary membrane content. Mol Biol Cell (2012) 0.79
Cell architecture: putting the building blocks together. Curr Opin Cell Biol (2012) 0.79
The oncoprotein BCL11A binds to orphan nuclear receptor TLX and potentiates its transrepressive function. PLoS One (2012) 0.79
SPICE--a previously uncharacterized protein required for centriole duplication and mitotic chromosome congression. J Cell Sci (2010) 0.79
Exploring the pole: an EMBO conference on centrosomes and spindle pole bodies. Nat Cell Biol (2008) 0.78
Remembrance of cilia past. Cell (2013) 0.77
Stem cells: A fateful age gap. Nature (2009) 0.75
Dispatch. Centrosome biology: a SAS-sy centriole in the cell cycle. Curr Biol (2003) 0.75