Estradiol modulates Kiss1 neuronal response to ghrelin.

PubWeight™: 0.89‹?›

🔗 View Article (PMC 3948981)

Published in Am J Physiol Endocrinol Metab on January 28, 2014

Authors

Renata Frazao1, Heather M Dungan Lemko, Regina P da Silva, Dhirender V Ratra, Charlotte E Lee, Kevin W Williams, Jeffrey M Zigman, Carol F Elias

Author Affiliations

1: Department of Internal Medicine, Division of Hypothalamic Research, University of Texas Southwestern Medical Center, Dallas, Texas;

Articles citing this

Differential gene regulation of GHSR signaling pathway in the arcuate nucleus and NPY neurons by fasting, diet-induced obesity, and 17β-estradiol. Mol Cell Endocrinol (2015) 0.80

Minireview: Metabolic control of the reproductive physiology: insights from genetic mouse models. Horm Behav (2014) 0.79

Distribution of the neuronal inputs to the ventral premammillary nucleus of male and female rats. Brain Res (2014) 0.77

Insulin and Leptin Signaling Interact in the Mouse Kiss1 Neuron during the Peripubertal Period. PLoS One (2015) 0.76

ERα in Tac2 Neurons Regulates Puberty Onset in Female Mice. Endocrinology (2016) 0.76

Ghrelin's control of food reward and body weight in the lateral hypothalamic area is sexually dimorphic. Physiol Behav (2017) 0.75

Leptin receptor null mice with reexpression of LepR in GnRHR expressing cells display elevated FSH levels but remain in a prepubertal state. Am J Physiol Regul Integr Comp Physiol (2016) 0.75

Hypothalamic action of phoenixin to control reproductive hormone secretion in females: importance of the orphan G protein-coupled receptor Gpr173. Am J Physiol Regul Integr Comp Physiol (2016) 0.75

The interaction of fasting, caloric restriction, and diet-induced obesity with 17β-estradiol on the expression of KNDy neuropeptides and their receptors in the female mouse. Mol Cell Endocrinol (2016) 0.75

AMPKα2 in Kiss1 Neurons Is Required for Reproductive Adaptations to Acute Metabolic Challenges in Adult Female Mice. Endocrinology (2016) 0.75

Regulation of gene expression by 17β-estradiol in the arcuate nucleus of the mouse through ERE-dependent and ERE-independent mechanisms. Steroids (2016) 0.75

GLP-1R Signaling Directly Activates Arcuate Nucleus Kisspeptin Action in Brain Slices but Does not Rescue Luteinizing Hormone Inhibition in Ovariectomized Mice During Negative Energy Balance. eNeuro (2017) 0.75

Tachykinin-1 in the central nervous system regulates adiposity in rodents. Endocrinology (2015) 0.75

Articles cited by this

Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature (1999) 17.72

Ghrelin induces adiposity in rodents. Nature (2000) 10.18

Regulation of Kiss1 gene expression in the brain of the female mouse. Endocrinology (2005) 4.48

Expression of ghrelin receptor mRNA in the rat and the mouse brain. J Comp Neurol (2006) 3.61

Regulation of gonadotropin-releasing hormone secretion by kisspeptin/dynorphin/neurokinin B neurons in the arcuate nucleus of the mouse. J Neurosci (2009) 2.78

Mouse cortical inhibitory neuron type that coexpresses somatostatin and calretinin. J Comp Neurol (2006) 2.47

Segregation of acute leptin and insulin effects in distinct populations of arcuate proopiomelanocortin neurons. J Neurosci (2010) 2.42

Minireview: From anorexia to obesity--the yin and yang of body weight control. Endocrinology (2003) 2.27

Control of fertility by metabolic cues. Am J Physiol (1996) 2.06

Coexpression of dynorphin and neurokinin B immunoreactivity in the rat hypothalamus: Morphologic evidence of interrelated function within the arcuate nucleus. J Comp Neurol (2006) 1.88

Hypothalamic pathways linking energy balance and reproduction. Am J Physiol Endocrinol Metab (2008) 1.75

Mating and agonistic behavior produce different patterns of Fos immunolabeling in the male Syrian hamster brain. Neuroscience (1995) 1.74

Ghrelin in the regulation of body weight and metabolism. Front Neuroendocrinol (2009) 1.73

The role of kisspeptin-GPR54 signaling in the tonic regulation and surge release of gonadotropin-releasing hormone/luteinizing hormone. J Neurosci (2007) 1.69

Body weight and food intake as initiating factors for puberty in the rat. J Physiol (1963) 1.68

RNAi-mediated silencing of estrogen receptor {alpha} in the ventromedial nucleus of hypothalamus abolishes female sexual behaviors. Proc Natl Acad Sci U S A (2006) 1.66

KiSS-1 messenger ribonucleic acid expression in the hypothalamus of the ewe is regulated by sex steroids and season. Endocrinology (2006) 1.66

Estradiol-dependent decrease in the orexigenic potency of ghrelin in female rats. Diabetes (2007) 1.62

Timing and completion of puberty in female mice depend on estrogen receptor alpha-signaling in kisspeptin neurons. Proc Natl Acad Sci U S A (2010) 1.62

Estrogen positive feedback to gonadotropin-releasing hormone (GnRH) neurons in the rodent: the case for the rostral periventricular area of the third ventricle (RP3V). Brain Res Rev (2007) 1.60

Discrete lesions reveal functional heterogeneity of suprachiasmatic structures in regulation of gonadotropin secretion in the female rat. Neuroendocrinology (1982) 1.55

Conditional gene targeting in the mouse nervous system: Insights into brain function and diseases. Pharmacol Ther (2007) 1.54

Topography in the preoptic region: differential regulation of appetitive and consummatory male sexual behaviors. Front Neuroendocrinol (2007) 1.49

Characterization of Kiss1 neurons using transgenic mouse models. Neuroscience (2010) 1.49

Molecular properties of Kiss1 neurons in the arcuate nucleus of the mouse. Endocrinology (2011) 1.21

Endogenous gamma-aminobutyric acid can excite gonadotropin-releasing hormone neurons. Endocrinology (2005) 1.20

The inhibitory effects of neurokinin B on GnRH pulse generator frequency in the female rat. Endocrinology (2011) 1.16

Regulation of estrogen receptor messenger ribonucleic acid in rat hypothalamus by sex steroid hormones. Mol Endocrinol (1991) 1.13

Ghrelin directly stimulates glucagon secretion from pancreatic alpha-cells. Mol Endocrinol (2011) 1.13

Depolarising and hyperpolarising actions of GABA(A) receptor activation on gonadotrophin-releasing hormone neurones: towards an emerging consensus. J Neuroendocrinol (2011) 1.10

Intracerebroventricular administration of ghrelin rapidly suppresses pulsatile luteinizing hormone secretion in ovariectomized rats. Biochem Biophys Res Commun (2001) 1.10

Ovarian steroid regulation of estrogen and progesterone receptor messenger ribonucleic acid in the anteroventral periventricular nucleus of the rat. J Neuroendocrinol (1996) 1.10

Decrease in luteinizing hormone pulse frequency during a five-hour peripheral ghrelin infusion in the ovariectomized rhesus monkey. J Clin Endocrinol Metab (2004) 1.05

Maternity: neural mechanisms, motivational processes, and physiological adaptations. Behav Neurosci (2010) 1.03

Effects of ghrelin on Kisspeptin mRNA expression in the hypothalamic medial preoptic area and pulsatile luteinising hormone secretion in the female rat. Neurosci Lett (2009) 1.02

Ghrelin, the peripheral hunger hormone. Ann Med (2007) 1.02

Leptin signaling and circuits in puberty and fertility. Cell Mol Life Sci (2012) 1.01

Ghrelin effects on gonadotropin secretion in male and female rats. Neurosci Lett (2004) 1.01

Suppression of the GnRH pulse generator by neurokinin B involves a κ-opioid receptor-dependent mechanism. Endocrinology (2012) 0.99

Comparative analysis of the effects of ghrelin and unacylated ghrelin on luteinizing hormone secretion in male rats. Endocrinology (2006) 0.99

Shift in Kiss1 cell activity requires estrogen receptor α. J Neurosci (2013) 0.98

Sex differences in the neural circuit that mediates female sexual receptivity. Front Neuroendocrinol (2011) 0.96

Age-related changes in hypothalamic androgen receptor and estrogen receptor alpha in male rats. J Comp Neurol (2009) 0.95

Neurobiological mechanisms underlying oestradiol negative and positive feedback regulation of gonadotrophin-releasing hormone neurones. J Neuroendocrinol (2009) 0.95

Glucose-mediated control of ghrelin release from primary cultures of gastric mucosal cells. Am J Physiol Endocrinol Metab (2012) 0.93

Orexin-saporin lesions of the medial septum impair spatial memory. Neuroscience (2005) 0.92

Effects of ghrelin upon gonadotropin-releasing hormone and gonadotropin secretion in adult female rats: in vivo and in vitro studies. Neuroendocrinology (2006) 0.91

Glutamate regulation of GnRH neuron excitability. Brain Res (2010) 0.91

Effects of estradiol on food intake and meal patterns for diets that differ in flavor and fat content. Physiol Behav (2010) 0.88

Ghrelin and reproduction: ghrelin as novel regulator of the gonadotropic axis. Vitam Horm (2008) 0.86

Role of the medial preoptic area/anterior hypothalamus in the control of masculine sexual behavior. Annu Rev Sex Res (1997) 0.84

Sex and regional differences in decrease of estrogen receptor alpha-immunoreactive cells by estrogen in rat hypothalamus and midbrain. Neurosci Lett (2009) 0.82

Ghrelin suppresses secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in women. J Clin Endocrinol Metab (2012) 0.81

Photoperiod influences the central effects of ghrelin on food intake, GH and LH secretion in sheep. Neuroendocrinology (2007) 0.80

Beyond the metabolic role of ghrelin: a new player in the regulation of reproductive function. Peptides (2011) 0.78

Articles by these authors

Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis. Neuron (2004) 7.15

Divergence of melanocortin pathways in the control of food intake and energy expenditure. Cell (2005) 7.04

Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis. Neuron (2006) 5.27

Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity. Nature (2007) 4.20

Mice lacking ghrelin receptors resist the development of diet-induced obesity. J Clin Invest (2005) 3.92

Melanocortin-4 receptors expressed by cholinergic neurons regulate energy balance and glucose homeostasis. Cell Metab (2011) 3.68

Expression of ghrelin receptor mRNA in the rat and the mouse brain. J Comp Neurol (2006) 3.61

The hypothalamic arcuate nucleus: a key site for mediating leptin's effects on glucose homeostasis and locomotor activity. Cell Metab (2005) 3.38

Transgenic mice expressing green fluorescent protein under the control of the melanocortin-4 receptor promoter. J Neurosci (2003) 3.08

Expression of melanocortin 4 receptor mRNA in the central nervous system of the rat. J Comp Neurol (2003) 3.05

Synaptic glutamate release by ventromedial hypothalamic neurons is part of the neurocircuitry that prevents hypoglycemia. Cell Metab (2007) 3.02

Leptin targets in the mouse brain. J Comp Neurol (2009) 2.80

Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice. J Clin Invest (2008) 2.77

Activation of central melanocortin pathways by fenfluramine. Science (2002) 2.71

The orexigenic hormone ghrelin defends against depressive symptoms of chronic stress. Nat Neurosci (2008) 2.64

Distinct hypothalamic neurons mediate estrogenic effects on energy homeostasis and reproduction. Cell Metab (2011) 2.61

Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility. Cell Metab (2010) 2.58

Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons. J Clin Invest (2002) 2.54

Segregation of acute leptin and insulin effects in distinct populations of arcuate proopiomelanocortin neurons. J Neurosci (2010) 2.42

High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons. Nat Neurosci (2011) 2.36

Serotonin reciprocally regulates melanocortin neurons to modulate food intake. Neuron (2006) 2.16

Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice. J Clin Invest (2012) 2.12

5-HT2CRs expressed by pro-opiomelanocortin neurons regulate energy homeostasis. Neuron (2008) 2.04

Disruption of leptin receptor expression in the pancreas directly affects beta cell growth and function in mice. J Clin Invest (2007) 1.99

Enhanced leptin sensitivity and improved glucose homeostasis in mice lacking suppressor of cytokine signaling-3 in POMC-expressing cells. Cell Metab (2006) 1.96

Ghrelin increases the rewarding value of high-fat diet in an orexin-dependent manner. Biol Psychiatry (2009) 1.87

Palmitic acid mediates hypothalamic insulin resistance by altering PKC-theta subcellular localization in rodents. J Clin Invest (2009) 1.77

Brain SIRT1: anatomical distribution and regulation by energy availability. J Neurosci (2008) 1.75

Hypothalamic pathways linking energy balance and reproduction. Am J Physiol Endocrinol Metab (2008) 1.75

Glucagon-like peptide-1-responsive catecholamine neurons in the area postrema link peripheral glucagon-like peptide-1 with central autonomic control sites. J Neurosci (2003) 1.74

Melanocortin 4 receptors reciprocally regulate sympathetic and parasympathetic preganglionic neurons. Cell (2013) 1.71

Leptin receptor expression in hindbrain Glp-1 neurons regulates food intake and energy balance in mice. J Clin Invest (2011) 1.65

Estradiol-dependent decrease in the orexigenic potency of ghrelin in female rats. Diabetes (2007) 1.62

PI3K signaling in the ventromedial hypothalamic nucleus is required for normal energy homeostasis. Cell Metab (2010) 1.57

Ghrelin mediates stress-induced food-reward behavior in mice. J Clin Invest (2011) 1.50

Leptin's effect on puberty in mice is relayed by the ventral premammillary nucleus and does not require signaling in Kiss1 neurons. J Clin Invest (2010) 1.49

Characterization of a novel binding partner of the melanocortin-4 receptor: attractin-like protein. Biochem J (2003) 1.49

Monitoring FoxO1 localization in chemically identified neurons. J Neurosci (2008) 1.39

Effects of the ritonavir price increase on the cost of protease inhibitor regimens in United States. Manag Care Interface (2006) 1.38

SIRT1 deacetylase in SF1 neurons protects against metabolic imbalance. Cell Metab (2011) 1.37

Serotonin 2C receptor activates a distinct population of arcuate pro-opiomelanocortin neurons via TRPC channels. Neuron (2011) 1.36

Excitatory and inhibitory local circuit input to the rat dorsal motor nucleus of the vagus originating from the nucleus tractus solitarius. Brain Res (2004) 1.32

A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin. Endocrinology (2012) 1.31

Selective enhancement of synaptic inhibition by hypocretin (orexin) in rat vagal motor neurons: implications for autonomic regulation. J Neurosci (2003) 1.28

Neuronal circuits that regulate feeding behavior and metabolism. Trends Neurosci (2013) 1.26

Central serotonin and melanocortin pathways regulating energy homeostasis. Ann N Y Acad Sci (2003) 1.24

A beta3-adrenergic-leptin-melanocortin circuit regulates behavioral and metabolic changes induced by chronic stress. Biol Psychiatry (2010) 1.24

Colocalization of ghrelin O-acyltransferase and ghrelin in gastric mucosal cells. Am J Physiol Endocrinol Metab (2009) 1.21

Use of laser-capture microdissection for the identification of marker genes for the ventromedial hypothalamic nucleus. J Neurosci (2005) 1.21

Ghrelin secretion stimulated by {beta}1-adrenergic receptors in cultured ghrelinoma cells and in fasted mice. Proc Natl Acad Sci U S A (2010) 1.20

Central nervous system regulation of energy metabolism: ghrelin versus leptin. Ann N Y Acad Sci (2008) 1.20

The ventral premammillary nucleus links fasting-induced changes in leptin levels and coordinated luteinizing hormone secretion. J Neurosci (2009) 1.18

Serotonin 2C receptors in pro-opiomelanocortin neurons regulate energy and glucose homeostasis. J Clin Invest (2013) 1.17

Steroidogenic factor 1 directs programs regulating diet-induced thermogenesis and leptin action in the ventral medial hypothalamic nucleus. Proc Natl Acad Sci U S A (2011) 1.17

Genetic tracing of Nav1.8-expressing vagal afferents in the mouse. J Comp Neurol (2011) 1.16

5-HT2CRs expressed by pro-opiomelanocortin neurons regulate insulin sensitivity in liver. Nat Neurosci (2010) 1.15

Ghrelin induces abdominal obesity via GHS-R-dependent lipid retention. Mol Endocrinol (2009) 1.14

Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells. Mol Metab (2013) 1.14

FOXO1 in the ventromedial hypothalamus regulates energy balance. J Clin Invest (2012) 1.13

Ghrelin directly stimulates glucagon secretion from pancreatic alpha-cells. Mol Endocrinol (2011) 1.13

Induction of leptin resistance by activation of cAMP-Epac signaling. Cell Metab (2011) 1.08

Characterization of a novel ghrelin cell reporter mouse. Regul Pept (2009) 1.08

Ghrelin's Roles in Stress, Mood, and Anxiety Regulation. Int J Pept (2010) 1.06

Hypothalamic sites of leptin action linking metabolism and reproduction. Neuroendocrinology (2010) 1.06

Neuroanatomical characterization of a growth hormone secretagogue receptor-green fluorescent protein reporter mouse. J Comp Neurol (2014) 1.05

Neuroanatomy of melanocortin-4 receptor pathway in the lateral hypothalamic area. J Comp Neurol (2012) 1.05

Chronic social defeat stress disrupts regulation of lipid synthesis. J Lipid Res (2010) 1.04

The acute effects of leptin require PI3K signaling in the hypothalamic ventral premammillary nucleus. J Neurosci (2011) 1.03

The role of ghrelin in reward-based eating. Biol Psychiatry (2012) 1.03

Female odors stimulate CART neurons in the ventral premammillary nucleus of male rats. Physiol Behav (2006) 1.00

Shift in Kiss1 cell activity requires estrogen receptor α. J Neurosci (2013) 0.98

A solitary hyperfunctioning thyroid nodule harboring thyroid carcinoma: review of the literature. Thyroid Res (2013) 0.98

Functional implications of limited leptin receptor and ghrelin receptor coexpression in the brain. J Comp Neurol (2012) 0.97

Neuropeptide Y Y1 receptor mRNA in rodent brain: distribution and colocalization with melanocortin-4 receptor. J Comp Neurol (2005) 0.97