Published in Leukemia on January 30, 2014
Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms. Nat Commun (2015) 1.19
Telomere maintenance and the etiology of adult glioma. Neuro Oncol (2015) 0.97
Germline duplication of ATG2B and GSKIP predisposes to familial myeloid malignancies. Nat Genet (2015) 0.94
Common germline variation at the TERT locus contributes to familial clustering of myeloproliferative neoplasms. Am J Hematol (2014) 0.90
Germ line variants predispose to both JAK2 V617F clonal hematopoiesis and myeloproliferative neoplasms. Blood (2016) 0.84
Telomerase dysregulation in the hippocampus of a rat model of depression: normalization by lithium. Int J Neuropsychopharmacol (2015) 0.81
Germline RBBP6 mutations in familial myeloproliferative neoplasms. Blood (2015) 0.79
TERT rs2736100 genotypes are associated with differential risk of myeloproliferative neoplasms in Swedish and Chinese male patient populations. Ann Hematol (2016) 0.78
Survival in patients with familial and sporadic myeloproliferative neoplasms. Blood (2015) 0.76
Familial Essential Thrombocythemia Associated with MPL W515L Mutation in Father and JAK2 V617F Mutation in Daughter. Case Rep Hematol (2014) 0.75
The TERT promoter mutation incidence is modified by germline TERT rs2736098 and rs2736100 polymorphisms in hepatocellular carcinoma. Oncotarget (2017) 0.75
Molecular determinants of pathogenesis and clinical phenotype in myeloproliferative neoplasms. Haematologica (2016) 0.75
Association Between the Telomerase rs2736098_TT Genotype and a Lower Risk of Chronic Hepatitis B and Cirrhosis in Chinese Males. Clin Transl Gastroenterol (2017) 0.75
ATG2B and GSKIP: 2 new genes predisposing to myeloid malignancies. Mol Cell Oncol (2015) 0.75
Whole-exome sequencing identifies novel candidate predisposition genes for familial polycythemia vera. Hum Genomics (2017) 0.75
A TET2 rs3733609 C/T genotype is associated with predisposition to the myeloproliferative neoplasms harboring JAK2V617F and confers a proliferative potential on erythroid lineages. Oncotarget (2016) 0.75
Specific association of human telomerase activity with immortal cells and cancer. Science (1994) 28.20
Sequence variants at the TERT-CLPTM1L locus associate with many cancer types. Nat Genet (2009) 6.91
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal. Proc Natl Acad Sci U S A (2013) 6.88
Genome-wide association study of hematological and biochemical traits in a Japanese population. Nat Genet (2010) 4.36
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nat Genet (2013) 4.35
Identification of seven loci affecting mean telomere length and their association with disease. Nat Genet (2013) 3.87
JAK2 haplotype is a major risk factor for the development of myeloproliferative neoplasms. Nat Genet (2009) 3.21
A germline JAK2 SNP is associated with predisposition to the development of JAK2(V617F)-positive myeloproliferative neoplasms. Nat Genet (2009) 3.10
Host genetic variation contributes to phenotypic diversity in myeloproliferative disorders. Blood (2007) 2.25
Telomerase reverse transcriptase locus polymorphisms and cancer risk: a field synopsis and meta-analysis. J Natl Cancer Inst (2012) 1.82
Inherited predisposition to myeloproliferative neoplasms. Ther Adv Hematol (2013) 1.06
Feedback regulation of telomerase reverse transcriptase: new insight into the evolving field of telomerase in cancer. Cell Signal (2013) 0.91
Telomere shortening in Ph-negative chronic myeloproliferative neoplasms: a biological marker of polycythemia vera and myelofibrosis, regardless of hydroxycarbamide therapy. Exp Hematol (2013) 0.82
Large-scale whole-genome sequencing of the Icelandic population. Nat Genet (2015) 4.54
Loss-of-function mutations in SLC30A8 protect against type 2 diabetes. Nat Genet (2014) 4.24
Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer. Nat Genet (2014) 2.39
Identification of a large set of rare complete human knockouts. Nat Genet (2015) 2.28
Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes. Nat Genet (2014) 1.92
Variants with large effects on blood lipids and the role of cholesterol and triglycerides in coronary disease. Nat Genet (2016) 1.71
Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease. Nat Genet (2015) 1.46
Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk. Nat Genet (2017) 1.44
Whole-genome sequencing identifies rare genotypes in COMP and CHADL associated with high risk of hip osteoarthritis. Nat Genet (2017) 1.39
Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma. Nat Commun (2015) 0.92
Loss-of-function variants in ATM confer risk of gastric cancer. Nat Genet (2015) 0.91
Weighting sequence variants based on their annotation increases power of whole-genome association studies. Nat Genet (2016) 0.88
Rare coding variants and X-linked loci associated with age at menarche. Nat Commun (2015) 0.87
A Splice Region Variant in LDLR Lowers Non-high Density Lipoprotein Cholesterol and Protects against Coronary Artery Disease. PLoS Genet (2015) 0.79
Identification of a novel susceptibility locus at 13q34 and refinement of the 20p12.2 region as a multi-signal locus associated with bladder cancer risk in individuals of European ancestry. Hum Mol Genet (2016) 0.76
Diversity in non-repetitive human sequences not found in the reference genome. Nat Genet (2017) 0.75
A sequence variant associating with educational attainment also affects childhood cognition. Sci Rep (2016) 0.75
The rate of meiotic gene conversion varies by sex and age. Nat Genet (2016) 0.75
A rare splice donor mutation in the haptoglobin gene associates with blood lipid levels and coronary artery disease. Hum Mol Genet (2017) 0.75
Effect of sequence variants on variance in glucose levels predicts type 2 diabetes risk and accounts for heritability. Nat Genet (2017) 0.75
Identification of sequence variants influencing immunoglobulin levels. Nat Genet (2017) 0.75