Published in Nat Genet on February 07, 2010
Mapping and analysis of chromatin state dynamics in nine human cell types. Nature (2011) 24.37
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
New genetic loci link adipose and insulin biology to body fat distribution. Nature (2015) 3.38
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet (2011) 3.18
New gene functions in megakaryopoiesis and platelet formation. Nature (2011) 3.14
Seventy-five genetic loci influencing the human red blood cell. Nature (2012) 2.77
Transethnic meta-analysis of genomewide association studies. Genet Epidemiol (2011) 2.53
Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits. Nat Genet (2011) 2.27
Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Nat Genet (2012) 2.05
Genetic variants associated with the white blood cell count in 13,923 subjects in the eMERGE Network. Hum Genet (2011) 2.00
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet (2015) 1.87
Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT). PLoS Genet (2011) 1.75
A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium. PLoS Genet (2011) 1.68
Multiple loci are associated with white blood cell phenotypes. PLoS Genet (2011) 1.65
Imputation of exome sequence variants into population- based samples and blood-cell-trait-associated loci in African Americans: NHLBI GO Exome Sequencing Project. Am J Hum Genet (2012) 1.60
European genome-wide association study identifies SLC14A1 as a new urinary bladder cancer susceptibility gene. Hum Mol Genet (2011) 1.58
Decreased extra-renal urate excretion is a common cause of hyperuricemia. Nat Commun (2012) 1.58
Genetic association analysis highlights new loci that modulate hematological trait variation in Caucasians and African Americans. Hum Genet (2010) 1.54
A meta-analysis and genome-wide association study of platelet count and mean platelet volume in african americans. PLoS Genet (2012) 1.53
Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci. Am J Hum Genet (2014) 1.47
A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects. Hum Genet (2013) 1.47
Identification of nine novel loci associated with white blood cell subtypes in a Japanese population. PLoS Genet (2011) 1.45
Polymorphisms in GCKR, SLC17A1 and SLC22A12 were associated with phenotype gout in Han Chinese males: a case-control study. BMC Med Genet (2015) 1.39
A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population. Nat Genet (2012) 1.37
Genetic analysis of hematological parameters in incipient lines of the collaborative cross. G3 (Bethesda) (2012) 1.35
A phenomics-based strategy identifies loci on APOC1, BRAP, and PLCG1 associated with metabolic syndrome phenotype domains. PLoS Genet (2011) 1.35
A genome-wide association study of the human metabolome in a community-based cohort. Cell Metab (2013) 1.33
Discovery and fine mapping of serum protein loci through transethnic meta-analysis. Am J Hum Genet (2012) 1.29
A genome-wide association study of serum uric acid in African Americans. BMC Med Genomics (2011) 1.28
Common dysfunctional variants in ABCG2 are a major cause of early-onset gout. Sci Rep (2013) 1.28
Genome-wide association mapping with longitudinal data. Genet Epidemiol (2012) 1.27
Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number. Genes Dev (2012) 1.23
Association of the rs738409 polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease. BMC Med Genet (2010) 1.20
Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index. Hum Mol Genet (2014) 1.20
Recent advances in understanding the genetic architecture of type 2 diabetes. Hum Mol Genet (2015) 1.16
ABCG2 dysfunction causes hyperuricemia due to both renal urate underexcretion and renal urate overload. Sci Rep (2014) 1.16
GeMes, clusters of DNA methylation under genetic control, can inform genetic and epigenetic analysis of disease. Am J Hum Genet (2014) 1.15
The germline sequence variant rs2736100_C in TERT associates with myeloproliferative neoplasms. Leukemia (2014) 1.15
HBS1L-MYB intergenic variants modulate fetal hemoglobin via long-range MYB enhancers. J Clin Invest (2014) 1.14
Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele. Hum Mol Genet (2011) 1.13
Mutations in zebrafish lrp2 result in adult-onset ocular pathogenesis that models myopia and other risk factors for glaucoma. PLoS Genet (2011) 1.11
Strong protective effect of the aldehyde dehydrogenase gene (ALDH2) 504lys (*2) allele against alcoholism and alcohol-induced medical diseases in Asians. Hum Genet (2011) 1.10
GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children. Hum Mol Genet (2012) 1.09
Genetic Loci implicated in erythroid differentiation and cell cycle regulation are associated with red blood cell traits. Mayo Clin Proc (2012) 1.05
Inherited genetic susceptibility to multiple myeloma. Leukemia (2013) 1.04
Genome-wide haplotype analysis of cis expression quantitative trait loci in monocytes. PLoS Genet (2013) 1.03
Correlation of rare coding variants in the gene encoding human glucokinase regulatory protein with phenotypic, cellular, and kinetic outcomes. J Clin Invest (2011) 1.03
A genome-wide association study identifies common variants influencing serum uric acid concentrations in a Chinese population. BMC Med Genomics (2014) 1.02
Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes. Ann Rheum Dis (2015) 1.02
Confounding and heterogeneity in genetic association studies with admixed populations. Am J Epidemiol (2013) 1.00
Genetic variants that confer resistance to malaria are associated with red blood cell traits in African-Americans: an electronic medical record-based genome-wide association study. G3 (Bethesda) (2013) 1.00
Loci affecting gamma-glutamyl transferase in adults and adolescents show age × SNP interaction and cardiometabolic disease associations. Hum Mol Genet (2011) 0.98
Implications of discoveries from genome-wide association studies in current cardiovascular practice. World J Cardiol (2011) 0.97
Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network. Hum Mol Genet (2013) 0.97
A genome wide association study identifies common variants associated with lipid levels in the Chinese population. PLoS One (2013) 0.95
Genome-wide association analyses based on whole-genome sequencing in Sardinia provide insights into regulation of hemoglobin levels. Nat Genet (2015) 0.95
A tour through the transcriptional landscape of platelets. Blood (2014) 0.94
Genomic modulators of the immune response. Trends Genet (2012) 0.94
PRISM offers a comprehensive genomic approach to transcription factor function prediction. Genome Res (2013) 0.94
Genome-wide association studies of hematologic phenotypes: a window into human hematopoiesis. Curr Opin Genet Dev (2013) 0.94
Disease risk factors identified through shared genetic architecture and electronic medical records. Sci Transl Med (2014) 0.94
Trim58 degrades Dynein and regulates terminal erythropoiesis. Dev Cell (2014) 0.93
Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians. Diabetes (2014) 0.93
Sequence variation at multiple loci influences red cell hemoglobin concentration. Blood (2010) 0.92
A multi-platform draft de novo genome assembly and comparative analysis for the Scarlet Macaw (Ara macao). PLoS One (2013) 0.92
The genetic architecture of liver enzyme levels: GGT, ALT and AST. Behav Genet (2013) 0.91
An integrated approach to defining genetic and environmental determinants for major clinical outcomes involving vitamin D. Mol Diagn Ther (2014) 0.91
Association between serum uric acid and the metabolic syndrome among a middle- and old-age Chinese population. Eur J Epidemiol (2013) 0.90
Genomics and epigenomics of the human glycome. Glycoconj J (2012) 0.90
Common germline variation at the TERT locus contributes to familial clustering of myeloproliferative neoplasms. Am J Hematol (2014) 0.90
Genetic determinants of haemolysis in sickle cell anaemia. Br J Haematol (2013) 0.89
Association of the lipoprotein receptor-related protein 2 gene with gout and non-additive interaction with alcohol consumption. Arthritis Res Ther (2013) 0.89
Association analysis of the SLC22A11 (organic anion transporter 4) and SLC22A12 (urate transporter 1) urate transporter locus with gout in New Zealand case-control sample sets reveals multiple ancestral-specific effects. Arthritis Res Ther (2013) 0.89
Expression of SLC2A9 isoforms in the kidney and their localization in polarized epithelial cells. PLoS One (2014) 0.89
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A genome-wide association study of nephrolithiasis in the Japanese population identifies novel susceptible Loci at 5q35.3, 7p14.3, and 13q14.1. PLoS Genet (2012) 0.88
Interrogating causal pathways linking genetic variants, small molecule metabolites, and circulating lipids. Genome Med (2014) 0.86
A genome-wide association study of saturated, mono- and polyunsaturated red blood cell fatty acids in the Framingham Heart Offspring Study. Prostaglandins Leukot Essent Fatty Acids (2014) 0.86
Genome-wide association study reveals constant and specific loci for hematological traits at three time stages in a White Duroc × Erhualian F2 resource population. PLoS One (2013) 0.86
Uric acid transporter ABCG2 is increased in the intestine of the 5/6 nephrectomy rat model of chronic kidney disease. Clin Exp Nephrol (2013) 0.86
Japan PGx Data Science Consortium Database: SNPs and HLA genotype data from 2994 Japanese healthy individuals for pharmacogenomics studies. J Hum Genet (2015) 0.85
Genome-wide Association Study of Platelet Count Identifies Ancestry-Specific Loci in Hispanic/Latino Americans. Am J Hum Genet (2016) 0.85
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A genome-wide association study for corneal curvature identifies the platelet-derived growth factor receptor α gene as a quantitative trait locus for eye size in white Europeans. Mol Vis (2013) 0.84
Lessons and Implications from Genome-Wide Association Studies (GWAS) Findings of Blood Cell Phenotypes. Genes (Basel) (2014) 0.84
Association of common variants in TNFRSF13B, TNFSF13, and ANXA3 with serum levels of non-albumin protein and immunoglobulin isotypes in Japanese. PLoS One (2012) 0.84
SORCS1 contributes to the development of renal disease in rats and humans. Physiol Genomics (2013) 0.83
Global genetic architecture of an erythroid quantitative trait locus, HMIP-2. Ann Hum Genet (2014) 0.83
Disruption of the Hbs1l-Myb locus causes hereditary persistence of fetal hemoglobin in a mouse model. Mol Cell Biol (2013) 0.83
Genome-wide association study identified SNP on 15q24 associated with bladder cancer risk in Japanese population. Hum Mol Genet (2014) 0.83
Rare coding variants in ALPL are associated with low serum alkaline phosphatase and low bone mineral density. J Bone Miner Res (2012) 0.83
Glucokinase regulatory protein: complexity at the crossroads of triglyceride and glucose metabolism. Curr Opin Lipidol (2015) 0.82
Alanine aminotransferase and risk of the metabolic syndrome: a linear dose-response relationship. PLoS One (2014) 0.82
Interactive effects of a common γ-glutamyltransferase 1 variant and low high-density lipoprotein-cholesterol on diabetic macro- and micro-angiopathy. Cardiovasc Diabetol (2015) 0.82
The genetics of common variation affecting platelet development, function and pharmaceutical targeting. J Thromb Haemost (2011) 0.82
Absence of association of a single-nucleotide polymorphism in the TERT-CLPTM1L locus with age-related phenotypes in a large multicohort study: the HALCyon programme. Aging Cell (2011) 0.82
Genome-wide association study on serum alkaline phosphatase levels in a Chinese population. BMC Genomics (2013) 0.81
Serum uric acid levels are associated with polymorphisms in the SLC2A9, SF1, and GCKR genes in a Chinese population. Acta Pharmacol Sin (2014) 0.81
Genetic variants at PSMD3 interact with dietary fat and carbohydrate to modulate insulin resistance. J Nutr (2013) 0.81
Quantitative trait locus linkage analysis in a large Amish pedigree identifies novel candidate loci for erythrocyte traits. Mol Genet Genomic Med (2013) 0.81
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Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science (2007) 51.70
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. Nat Genet (2008) 20.73
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