Deficiency of the 15-kDa selenoprotein led to cytoskeleton remodeling and non-apoptotic membrane blebbing through a RhoA/ROCK pathway.

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Published in Biochem Biophys Res Commun on December 18, 2014

Authors

Jeyoung Bang1, Mihyun Jang2, Jang Hoe Huh2, Ji-Woon Na2, Myoungsup Shim3, Bradley A Carlson4, Ryuta Tobe4, Petra A Tsuji5, Vadim N Gladyshev6, Dolph L Hatfield4, Byeong Jae Lee7

Author Affiliations

1: School of Biological Sciences, Seoul National University, Seoul 151-742, Republic of Korea; Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul 151-742, Republic of Korea.
2: School of Biological Sciences, Seoul National University, Seoul 151-742, Republic of Korea.
3: School of Biological Sciences, Seoul National University, Seoul 151-742, Republic of Korea; Institute of Molecular Biology and Genetics, Seoul National University, Seoul 151-742, Republic of Korea.
4: Mouse Cancer Genetics Program, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
5: Department of Biological Sciences, Towson University, Towson, MD 21252, USA.
6: Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
7: School of Biological Sciences, Seoul National University, Seoul 151-742, Republic of Korea; Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul 151-742, Republic of Korea; Institute of Molecular Biology and Genetics, Seoul National University, Seoul 151-742, Republic of Korea. Electronic address: imbglmg@snu.ac.kr.

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