Published in Development on February 01, 2014
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Genetically distinct cardial cells within the Drosophila heart. Genesis (2000) 1.05
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JAK/Stat signaling regulates heart precursor diversification in Drosophila. Development (2011) 0.92
Two forkhead transcription factors regulate the division of cardiac progenitor cells by a Polo-dependent pathway. Dev Cell (2012) 0.87
Notch regulates numb: integration of conditional and autonomous cell fate specification. Development (2010) 0.86
The complex containing Drosophila Myb and RB/E2F2 regulates cytokinesis in a histone H2Av-dependent manner. Mol Cell Biol (2013) 0.81
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Scanning human gene deserts for long-range enhancers. Science (2003) 9.75
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A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms. Nature (2004) 5.24
High-resolution DNA-binding specificity analysis of yeast transcription factors. Genome Res (2009) 5.11
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Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo. EMBO J (2010) 4.78
The genome of the Western clawed frog Xenopus tropicalis. Science (2010) 4.70
Universal protein-binding microarrays for the comprehensive characterization of the DNA-binding specificities of transcription factors. Nat Protoc (2009) 3.48
Specific DNA-binding by apicomplexan AP2 transcription factors. Proc Natl Acad Sci U S A (2008) 3.10
A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell (2009) 3.02
Mutations in the RNA granule component TDRD7 cause cataract and glaucoma. Science (2011) 2.78
Computation-based discovery of related transcriptional regulatory modules and motifs using an experimentally validated combinatorial model. Genome Res (2002) 2.74
Predicting tissue-specific enhancers in the human genome. Genome Res (2007) 2.72
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Noncooperative interactions between transcription factors and clustered DNA binding sites enable graded transcriptional responses to environmental inputs. Mol Cell (2010) 2.43
CREME: a framework for identifying cis-regulatory modules in human-mouse conserved segments. Bioinformatics (2003) 2.42
A high-resolution enhancer atlas of the developing telencephalon. Cell (2013) 2.34
Evaluation of methods for modeling transcription factor sequence specificity. Nat Biotechnol (2013) 2.34
The DNA sequence and biology of human chromosome 19. Nature (2004) 2.29
Generation and annotation of the DNA sequences of human chromosomes 2 and 4. Nature (2005) 2.27
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Homotypic clusters of transcription factor binding sites are a key component of human promoters and enhancers. Genome Res (2010) 2.12
The Vibrio harveyi master quorum-sensing regulator, LuxR, a TetR-type protein is both an activator and a repressor: DNA recognition and binding specificity at target promoters. Mol Microbiol (2008) 2.11
Distinguishing direct versus indirect transcription factor-DNA interactions. Genome Res (2009) 2.05
Genomic regions flanking E-box binding sites influence DNA binding specificity of bHLH transcription factors through DNA shape. Cell Rep (2013) 2.03
Protein binding microarrays (PBMs) for rapid, high-throughput characterization of the sequence specificities of DNA binding proteins. Methods Mol Biol (2006) 2.00
Genome-wide promoter analysis of the SOX4 transcriptional network in prostate cancer cells. Cancer Res (2009) 1.97
CREME: Cis-Regulatory Module Explorer for the human genome. Nucleic Acids Res (2004) 1.96
Expression-guided in silico evaluation of candidate cis regulatory codes for Drosophila muscle founder cells. PLoS Comput Biol (2006) 1.88
Genome-wide discovery of human heart enhancers. Genome Res (2010) 1.85
New fluorescent protein reporters for use with the Drosophila Gal4 expression system and for vital detection of balancer chromosomes. Genesis (2002) 1.80
Using peripheral blood mononuclear cells to determine a gene expression profile of acute ischemic stroke: a pilot investigation. Circulation (2005) 1.79
LUX ARRHYTHMO encodes a nighttime repressor of circadian gene expression in the Arabidopsis core clock. Curr Biol (2011) 1.78
Overexpression of the small mitochondrial Hsp22 extends Drosophila life span and increases resistance to oxidative stress. FASEB J (2004) 1.77
Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae. Genome Res (2007) 1.75
Principles of dimer-specific gene regulation revealed by a comprehensive characterization of NF-κB family DNA binding. Nat Immunol (2011) 1.72
Microarray analyses of newborn mouse ovaries lacking Nobox. Biol Reprod (2007) 1.67
Toxicological effect of ZnO nanoparticles based on bacteria. Langmuir (2008) 1.65
Neurological effects of high-dose idebenone in patients with Friedreich's ataxia: a randomised, placebo-controlled trial. Lancet Neurol (2007) 1.64
ECRbase: database of evolutionary conserved regions, promoters, and transcription factor binding sites in vertebrate genomes. Bioinformatics (2006) 1.58
A statistical model for investigating binding probabilities of DNA nucleotide sequences using microarrays. Biometrics (2002) 1.54
An integrated strategy for analyzing the unique developmental programs of different myoblast subtypes. PLoS Genet (2006) 1.51
Identification of clustered YY1 binding sites in imprinting control regions. Genome Res (2006) 1.51
Variable locus length in the human genome leads to ascertainment bias in functional inference for non-coding elements. Bioinformatics (2009) 1.49
Dcode.org anthology of comparative genomic tools. Nucleic Acids Res (2005) 1.49
Design of compact, universal DNA microarrays for protein binding microarray experiments. J Comput Biol (2008) 1.45
Reciprocal regulatory interactions between the Notch and Ras signaling pathways in the Drosophila embryonic mesoderm. Dev Biol (2002) 1.45
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Evolution of T1 black holes in patients with multiple sclerosis imaged monthly for 4 years. Brain (2003) 1.43
DiRE: identifying distant regulatory elements of co-expressed genes. Nucleic Acids Res (2008) 1.42
Human-zebrafish non-coding conserved elements act in vivo to regulate transcription. Nucleic Acids Res (2005) 1.39
Precise temporal control of the eye regulatory gene Pax6 via enhancer-binding site affinity. Genes Dev (2010) 1.39
Comparative analysis of chicken chromosome 28 provides new clues to the evolutionary fragility of gene-rich vertebrate regions. Genome Res (2007) 1.36
Non-DNA-binding cofactors enhance DNA-binding specificity of a transcriptional regulatory complex. Mol Syst Biol (2011) 1.34
The effect of surface electrical stimulation on hyolaryngeal movement in normal individuals at rest and during swallowing. J Appl Physiol (1985) (2006) 1.34
Modulefinder: a tool for computational discovery of cis regulatory modules. Pac Symp Biocomput (2005) 1.33
Curated collection of yeast transcription factor DNA binding specificity data reveals novel structural and gene regulatory insights. Genome Biol (2011) 1.32
Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of disease-associated genes. Nat Struct Mol Biol (2011) 1.31
Meta-analysis discovery of tissue-specific DNA sequence motifs from mammalian gene expression data. BMC Bioinformatics (2006) 1.28
Short-term calorie restriction in male mice feminizes gene expression and alters key regulators of conserved aging regulatory pathways. PLoS One (2009) 1.28
Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning. Genes Dev (2012) 1.24
Transcriptional regulation and stabilization of left-right neuronal identity in C. elegans. Genes Dev (2009) 1.17
The CLAMP protein links the MSL complex to the X chromosome during Drosophila dosage compensation. Genes Dev (2013) 1.16
Using protein design algorithms to understand the molecular basis of disease caused by protein-DNA interactions: the Pax6 example. Nucleic Acids Res (2010) 1.16
Using a structural and logics systems approach to infer bHLH-DNA binding specificity determinants. Nucleic Acids Res (2011) 1.15
Inferring condition-specific transcription factor function from DNA binding and gene expression data. Mol Syst Biol (2007) 1.13
iSyTE: integrated Systems Tool for Eye gene discovery. Invest Ophthalmol Vis Sci (2012) 1.11
A machine learning approach for identifying novel cell type-specific transcriptional regulators of myogenesis. PLoS Genet (2012) 1.10
Elevated cerebral blood flow velocities in Fabry disease with reversal after enzyme replacement. Stroke (2002) 1.10
Dual transcriptional activator and repressor roles of TBX20 regulate adult cardiac structure and function. Hum Mol Genet (2012) 1.08
DNA-binding specificity changes in the evolution of forkhead transcription factors. Proc Natl Acad Sci U S A (2013) 1.08
Genome-wide identification of conserved regulatory function in diverged sequences. Genome Res (2011) 1.07
Epidemiological survey of Angiostrongylus cantonensis in the west-central region of Guangdong Province, China. Parasitol Res (2011) 1.07
Meta-profiles of gene expression during aging: limited similarities between mouse and human and an unexpectedly decreased inflammatory signature. PLoS One (2012) 1.06
Molecular mechanism underlying the regulatory specificity of a Drosophila homeodomain protein that specifies myoblast identity. Development (2012) 1.05
Effects of HMGN variants on the cellular transcription profile. Nucleic Acids Res (2011) 1.05
Tissue-specific and ubiquitous expression patterns from alternative promoters of human genes. PLoS One (2010) 1.04
Identifying regulatory elements in eukaryotic genomes. Brief Funct Genomic Proteomic (2009) 1.02
Conservation and regulatory associations of a wide affinity range of mouse transcription factor binding sites. Genomics (2010) 1.02
Predicting the binding preference of transcription factors to individual DNA k-mers. Bioinformatics (2008) 1.01
Global gene expression analysis of murine limb development. PLoS One (2011) 1.01
The MARVEL domain protein, Singles Bar, is required for progression past the pre-fusion complex stage of myoblast fusion. Dev Biol (2007) 1.00
Highly parallel assays of tissue-specific enhancers in whole Drosophila embryos. Nat Methods (2013) 1.00