Published in Int J Hematol Oncol Stem Cell Res on January 01, 2014
New insight into adiponectin role in obesity and obesity-related diseases. Biomed Res Int (2014) 1.24
Persistent organic pollutants and obesity: are they potential mechanisms for breast cancer promotion? Endocr Relat Cancer (2015) 0.79
Obesity and cancer: the role of adipose tissue and adipo-cytokines-induced chronic inflammation. J Cancer (2016) 0.77
Mechanisms linking obesity to altered metabolism in mice colon carcinogenesis. Oncotarget (2015) 0.77
Correlation of leptin receptor expression with BMI in differential grades of human meningiomas. Oncol Lett (2016) 0.75
Leptin promotes epithelial-mesenchymal transition of breast cancer via the upregulation of pyruvate kinase M2. J Exp Clin Cancer Res (2016) 0.75
Adipocytes secreted leptin is a pro-tumor factor for survival of multiple myeloma under chemotherapy. Oncotarget (2016) 0.75
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat Cell Biol (2002) 17.41
Leptin and the regulation of body weight in mammals. Nature (1998) 14.84
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med (2002) 14.15
AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. Cell Metab (2005) 13.91
Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway. Mol Cell (2002) 11.65
Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature (2003) 9.79
A novel serum protein similar to C1q, produced exclusively in adipocytes. J Biol Chem (1995) 9.72
Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. J Clin Invest (2006) 9.49
Developmental origin of fat: tracking obesity to its source. Cell (2007) 8.80
Abnormal splicing of the leptin receptor in diabetic mice. Nature (1996) 7.71
AdipoQ is a novel adipose-specific gene dysregulated in obesity. J Biol Chem (1996) 6.93
Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proc Natl Acad Sci U S A (2001) 6.20
Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex. Diabetologia (2003) 5.91
PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein. Diabetes (2001) 5.18
ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism. Trends Endocrinol Metab (2002) 4.64
Distributions of leptin receptor mRNA isoforms in the rat brain. J Comp Neurol (1998) 4.30
A prospective study of endogenous estrogens and breast cancer in postmenopausal women. J Natl Cancer Inst (1995) 4.29
From lesions to leptin: hypothalamic control of food intake and body weight. Neuron (1999) 4.18
T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin. Proc Natl Acad Sci U S A (2004) 3.90
The leptin receptor. J Biol Chem (1997) 3.76
Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology. Nutrition (2000) 3.58
Interaction between hamartin and tuberin, the TSC1 and TSC2 gene products. Hum Mol Genet (1998) 3.54
Activation of downstream signals by the long form of the leptin receptor. J Biol Chem (2000) 3.52
Adiponectin: more than just another fat cell hormone? Diabetes Care (2003) 3.30
Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase. Mol Cell Biol (2000) 3.27
Leptin: a review of its peripheral actions and interactions. Int J Obes Relat Metab Disord (2002) 3.09
AMPK, the metabolic syndrome and cancer. Trends Pharmacol Sci (2005) 3.04
Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis. Proc Natl Acad Sci U S A (2004) 2.85
Adiponectin: A novel adipokine linking adipocytes and vascular function. J Clin Endocrinol Metab (2004) 2.74
Adiponectin and breast cancer risk. J Clin Endocrinol Metab (2004) 2.72
Leptin receptor signaling and the regulation of mammalian physiology. Recent Prog Horm Res (2004) 2.67
Leptin in immunology. J Immunol (2005) 2.62
Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues. Proc Natl Acad Sci U S A (1997) 2.57
Association of serum adiponectin levels with breast cancer risk. Clin Cancer Res (2003) 2.35
Adiponectin and cancer: a systematic review. Br J Cancer (2006) 2.33
Adipose tissue: the new endocrine organ? A review article. Dig Dis Sci (2008) 2.26
Crystal structure of the obese protein leptin-E100. Nature (1997) 2.22
Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4. Cancer Res (2002) 2.20
Serum adiponectin and leptin levels in Taiwanese breast cancer patients. Cancer Lett (2005) 2.13
Serum adiponectin levels are inversely associated with overall and central fat distribution but are not directly regulated by acute fasting or leptin administration in humans: cross-sectional and interventional studies. J Clin Endocrinol Metab (2003) 2.09
Plasma adiponectin concentrations and risk of incident breast cancer. J Clin Endocrinol Metab (2007) 2.07
Adiponectin acts as an endogenous antithrombotic factor. Arterioscler Thromb Vasc Biol (2005) 1.88
Adipose tissue: a regulator of inflammation. Best Pract Res Clin Endocrinol Metab (2005) 1.86
Adiponectin and its receptors are expressed in bone-forming cells. Bone (2004) 1.86
Circulating levels of leptin, adiposity and breast cancer risk. Br J Cancer (2009) 1.78
Leptin expression in colorectal and breast cancer patients. Int J Mol Med (2000) 1.58
Adiponectin is synthesized and secreted by human and murine cardiomyocytes. FEBS Lett (2005) 1.58
AMPK as a mediator of hormonal signalling. J Mol Endocrinol (2009) 1.53
The association of metabolic syndrome with triple-negative breast cancer. Breast Cancer Res Treat (2009) 1.40
Characterizaton of short isoforms of the leptin receptor in rat cerebral microvessels and of brain uptake of leptin in mouse models of obesity. Endocrinology (2002) 1.36
Plasma leptin and breast cancer risk: a prospective study in northern Sweden. Breast Cancer Res Treat (2004) 1.35
Leptin and leptin receptor polymorphisms are associated with increased risk and poor prognosis of breast carcinoma. BMC Cancer (2006) 1.35
Mitogenic stimulation of human breast cancer cells in a growth factor-defined medium: synergistic action of insulin and estrogen. J Cell Physiol (1988) 1.29
Variants of the adiponectin and adiponectin receptor 1 genes and breast cancer risk. Cancer Res (2008) 1.28
Threading analysis suggests that the obese gene product may be a helical cytokine. FEBS Lett (1995) 1.26
Adipocytokines and breast cancer risk. Chin Med J (Engl) (2007) 1.23
Upper abdominal obesity, insulin resistance and breast cancer risk. Int J Obes Relat Metab Disord (2002) 1.19
Relationship of serum adiponectin and resistin levels with breast cancer risk. J Korean Med Sci (2007) 1.19
Adiponectin and leptin in maternal serum, cord blood, and breast milk. Clin Chem (2006) 1.12
Associations among lipids, leptin, and leptin receptor gene Gin223Arg polymorphisms and breast cancer in China. Biol Trace Elem Res (2008) 1.08
Adiponectin--it's all about the modifications. Int J Biochem Cell Biol (2010) 1.06
Disturbed secretion of mutant adiponectin associated with the metabolic syndrome. Biochem Biophys Res Commun (2003) 1.05
Hypothalamic fatty acid metabolism: a housekeeping pathway that regulates food intake. Bioessays (2007) 1.04
Presence of leptin in breast cell lines and breast tumors. Biochem Biophys Res Commun (1999) 1.03
Salivary gland epithelial cells: a new source of the immunoregulatory hormone adiponectin. Arthritis Rheum (2006) 1.02
Structural organization and chromosomal assignment of the human obese gene. J Biol Chem (1995) 1.00
Leptin modulates extracellular matrix molecules and metalloproteinases: possible implications for trophoblast invasion. Mol Hum Reprod (2000) 1.00
Plasma leptin levels and risk of breast cancer in premenopausal women. Cancer Prev Res (Phila) (2011) 1.00
Total body aromatization in postmenopausal breast cancer patients is strongly correlated to plasma leptin levels. J Steroid Biochem Mol Biol (2007) 0.94
Reduced response to adiponectin and lower abundance of adiponectin receptor proteins in type 2 diabetic monocytes. FEBS Lett (2008) 0.94
Leptin--from regulation of fat metabolism to stimulation of breast cancer growth. Pathol Oncol Res (2006) 0.94
Organization of the gene for gelatin-binding protein (GBP28). Gene (1999) 0.93
Acute intravenous leptin infusion increases glucose turnover but not skeletal muscle glucose uptake in ob/ob mice. Diabetes (1999) 0.92
Tissue levels of adiponectin in breast cancer patients. Med Oncol (2007) 0.92
Leptin regulation of aromatase activity in adipose stromal cells from regularly cycling women. Ginekol Pol (1999) 0.91
Endothelial cell IL-8, a new target for adiponectin: implications in vascular protection. Circ Res (2005) 0.86
Associations between adiponectin and two different cancers: breast and colon. Asian Pac J Cancer Prev (2012) 0.86
Is there any correlation among adiponectin levels in serum, tumor tissue and normal tissue of the same patients wih breast cancer? J BUON (2011) 0.84
"Obese" protein slims mice. Science (1995) 0.83
Plasma Leptin, hTERT Gene Expression, and Anthropometric Measures in Obese and Non-Obese Women with Breast Cancer. Breast Cancer (Auckl) (2011) 0.83
Tissue leptin levels in patients with breast cancer. J BUON (2010) 0.79