Ernesto Canalis

Author PubWeight™ 73.22‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Age-related changes in trabecular architecture differ in female and male C57BL/6J mice. J Bone Miner Res 2007 3.38
2 Growth hormone, insulin-like growth factors, and the skeleton. Endocr Rev 2008 2.64
3 Bone morphogenetic proteins and their antagonists. Rev Endocr Metab Disord 2006 2.03
4 Glucocorticoid-induced osteoporosis: an update. Trends Endocrinol Metab 2006 1.91
5 Notch inhibits osteoblast differentiation and causes osteopenia. Endocrinology 2008 1.78
6 Notch 1 overexpression inhibits osteoblastogenesis by suppressing Wnt/beta-catenin but not bone morphogenetic protein signaling. J Biol Chem 2006 1.61
7 Skeletal overexpression of gremlin impairs bone formation and causes osteopenia. Endocrinology 2004 1.58
8 Notch 1 impairs osteoblastic cell differentiation. Endocrinology 2003 1.57
9 PPARG by dietary fat interaction influences bone mass in mice and humans. J Bone Miner Res 2008 1.50
10 Notch and the skeleton. Mol Cell Biol 2009 1.49
11 A soluble bone morphogenetic protein type IA receptor increases bone mass and bone strength. Proc Natl Acad Sci U S A 2012 1.48
12 A soluble activin type IIA receptor induces bone formation and improves skeletal integrity. Proc Natl Acad Sci U S A 2008 1.42
13 Infrared analysis of the mineral and matrix in bones of osteonectin-null mice and their wildtype controls. J Bone Miner Res 2003 1.39
14 The ternary IGF complex influences postnatal bone acquisition and the skeletal response to intermittent parathyroid hormone. J Endocrinol 2006 1.37
15 Osteonectin-null mutation compromises osteoblast formation, maturation, and survival. Endocrinology 2003 1.37
16 The fate of circulating osteoblasts. N Engl J Med 2005 1.36
17 Expression and regulation of CCN genes in murine osteoblasts. Bone 2005 1.32
18 Serum IGF-1 determines skeletal strength by regulating subperiosteal expansion and trait interactions. J Bone Miner Res 2009 1.29
19 Nephroblastoma overexpressed (Nov) inhibits osteoblastogenesis and causes osteopenia. J Biol Chem 2007 1.28
20 Genetic dissection of mouse distal chromosome 1 reveals three linked BMD QTLs with sex-dependent regulation of bone phenotypes. J Bone Miner Res 2007 1.26
21 Effects of cortisol and bone morphogenetic protein-2 on stromal cell differentiation: correlation with CCAAT-enhancer binding protein expression. Bone 2002 1.22
22 CCAAT/enhancer binding protein homologous protein (DDIT3) induces osteoblastic cell differentiation. Endocrinology 2003 1.21
23 Drug-induced osteoporosis: mechanisms and clinical implications. Am J Med 2010 1.15
24 CCAAT/Enhancer-binding protein homologous protein (CHOP) decreases bone formation and causes osteopenia. Bone 2006 1.14
25 Misexpression of CCAAT/enhancer binding protein beta causes osteopenia. J Endocrinol 2009 1.14
26 Conditional deletion of gremlin causes a transient increase in bone formation and bone mass. J Biol Chem 2007 1.12
27 Skeletal overexpression of connective tissue growth factor impairs bone formation and causes osteopenia. Endocrinology 2008 1.08
28 Notch regulation of bone development and remodeling and related skeletal disorders. Calcif Tissue Int 2011 1.05
29 Connective tissue growth factor enhances osteoblastogenesis in vitro. J Biol Chem 2008 1.02
30 The heparin-binding domain of IGFBP-2 has insulin-like growth factor binding-independent biologic activity in the growing skeleton. J Biol Chem 2011 1.02
31 Notch signaling in skeletal health and disease. Eur J Endocrinol 2013 1.00
32 Reciprocal regulation of Notch and nuclear factor of activated T-cells (NFAT) c1 transactivation in osteoblasts. J Biol Chem 2010 0.99
33 C/EBP homologous protein is necessary for normal osteoblastic function. J Cell Biochem 2006 0.99
34 A novel spontaneous mutation of Irs1 in mice results in hyperinsulinemia, reduced growth, low bone mass and impaired adipogenesis. J Endocrinol 2009 0.97
35 Cortisol regulates the expression of Notch in osteoblasts. J Cell Biochem 2002 0.97
36 AU-rich elements in the collagenase 3 mRNA mediate stabilization of the transcript by cortisol in osteoblasts. J Biol Chem 2003 0.95
37 The mutation ROR2W749X, linked to human BDB, is a recessive mutation in the mouse, causing brachydactyly, mediating patterning of joints and modeling recessive Robinow syndrome. Development 2008 0.92
38 HES1 (hairy and enhancer of split 1) is a determinant of bone mass. J Biol Chem 2010 0.92
39 Bone loss or lost bone: rationale and recommendations for the diagnosis and treatment of early postmenopausal bone loss. Curr Osteoporos Rep 2009 0.91
40 Effects of activated T cells on osteoclastogenesis depend on how they are activated. Bone 2004 0.90
41 Twisted gastrulation, a bone morphogenetic protein agonist/antagonist, is not required for post-natal skeletal function. Bone 2006 0.90
42 Activated alveolar epithelial cells initiate fibrosis through autocrine and paracrine secretion of connective tissue growth factor. Am J Physiol Lung Cell Mol Physiol 2014 0.88
43 Glucocorticoid-induced osteoporosis in rheumatic diseases. Clinics (Sao Paulo) 2010 0.87
44 Nuclear factor of activated T-cells (NFAT)C2 inhibits Notch receptor signaling in osteoblasts. J Biol Chem 2012 0.86
45 Overexpression of twisted gastrulation inhibits bone morphogenetic protein action and prevents osteoblast cell differentiation in vitro. Endocrinology 2005 0.86
46 Notch suppresses nuclear factor of activated T cells (NFAT) transactivation and Nfatc1 expression in chondrocytes. Endocrinology 2012 0.86
47 Gene delivery by retroviruses. Methods Mol Biol 2008 0.85
48 BMD regulation on mouse distal chromosome 1, candidate genes, and response to ovariectomy or dietary fat. J Bone Miner Res 2011 0.84
49 Hairy and Enhancer of Split-related with YRPW motif (HEY)2 regulates bone remodeling in mice. J Biol Chem 2013 0.82
50 Activation of the ERK pathway in osteoblastic cells, role of gremlin and BMP-2. J Cell Biochem 2008 0.82
51 Loss of gremlin delays primordial follicle assembly but does not affect female fertility in mice. Biol Reprod 2011 0.81
52 Bone morphogenetic protein-2 suppresses collagenase-3 promoter activity in osteoblasts through a runt domain factor 2 binding site. J Cell Physiol 2005 0.81
53 Col3.6-HSD2 transgenic mice: a glucocorticoid loss-of-function model spanning early and late osteoblast differentiation. Bone 2010 0.81
54 Deficiency of Sef is associated with increased postnatal cortical bone mass by regulating Runx2 activity. J Bone Miner Res 2014 0.81
55 Role of the RAM domain and ankyrin repeats on notch signaling and activity in cells of osteoblastic lineage. J Bone Miner Res 2006 0.80
56 Activation of Nfatc2 in osteoblasts causes osteopenia. J Cell Physiol 2015 0.79
57 Nemo-like kinase inhibits osteoblastogenesis by suppressing bone morphogenetic protein and WNT canonical signaling. J Cell Biochem 2012 0.79
58 Management of glucocorticoid induced osteoporosis in premenopausal women with autoimmune disease. Autoimmun Rev 2003 0.78
59 Glucocorticoid-induced osteoporosis: clinical and therapeutic aspects. Arq Bras Endocrinol Metabol 2007 0.78
60 Transcriptional regulation of collagenase-3 by interleukin-1 alpha in osteoblasts. J Cell Biochem 2003 0.76
61 Treatment of glucocorticoid-induced osteoporsis. Ther Adv Musculoskelet Dis 2009 0.76
62 11beta-hydroxysteroid dehydrogenase, an amplifier of glucocorticoid action in osteoblasts. J Bone Miner Res 2002 0.76
63 Nephroblastoma overexpressed (Nov) induces gremlin in ST-2 stromal cell lines by post-transcriptional mechanisms. J Cell Biochem 2011 0.76
64 Transgenic overexpression of gremlin results in developmental defects in enamel and dentin in mice. Connect Tissue Res 2008 0.75
65 Connective tissue growth factor (CTGF) transactivates nuclear factor of activated T-cells (NFAT) in cells of the osteoblastic lineage. J Cell Biochem 2010 0.75
66 Cortisol Enhances the Expression of mac25/Insulin-Like Growth Factor-Binding Protein-Related Protein-1 in Cultured Osteoblasts* *This work was supported by NIDDK Grant DK-45227 and a scholarship (to R.C.P.) from Fundação Coordenação de Aperfeiçoa mento de Pessoal de Nível Superior (CAPES), Universidade de São Paulo (São Paulo, Brazil). Endocrinology 1999 0.75
67 Bone Morphogenetic Proteins Induce Gremlin, a Protein That Limits Their Activity in Osteoblasts* *This work was supported by NIAMSD Grant AR-21707. Endocrinology 2000 0.75