1
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Age-related changes in trabecular architecture differ in female and male C57BL/6J mice.
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3.38
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2
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Growth hormone, insulin-like growth factors, and the skeleton.
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2.64
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3
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Bone morphogenetic proteins and their antagonists.
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4
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Glucocorticoid-induced osteoporosis: an update.
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1.91
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5
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Notch inhibits osteoblast differentiation and causes osteopenia.
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1.78
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6
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Notch 1 overexpression inhibits osteoblastogenesis by suppressing Wnt/beta-catenin but not bone morphogenetic protein signaling.
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J Biol Chem
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2006
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1.61
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7
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Skeletal overexpression of gremlin impairs bone formation and causes osteopenia.
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1.58
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8
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Notch 1 impairs osteoblastic cell differentiation.
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2003
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1.57
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9
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PPARG by dietary fat interaction influences bone mass in mice and humans.
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1.50
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10
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Notch and the skeleton.
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Mol Cell Biol
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1.49
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11
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A soluble bone morphogenetic protein type IA receptor increases bone mass and bone strength.
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Proc Natl Acad Sci U S A
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1.48
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12
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A soluble activin type IIA receptor induces bone formation and improves skeletal integrity.
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Proc Natl Acad Sci U S A
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2008
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1.42
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13
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Infrared analysis of the mineral and matrix in bones of osteonectin-null mice and their wildtype controls.
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J Bone Miner Res
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2003
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1.39
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14
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The ternary IGF complex influences postnatal bone acquisition and the skeletal response to intermittent parathyroid hormone.
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J Endocrinol
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2006
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1.37
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15
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Osteonectin-null mutation compromises osteoblast formation, maturation, and survival.
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1.37
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16
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The fate of circulating osteoblasts.
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N Engl J Med
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2005
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1.36
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17
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Expression and regulation of CCN genes in murine osteoblasts.
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Bone
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1.32
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18
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Serum IGF-1 determines skeletal strength by regulating subperiosteal expansion and trait interactions.
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J Bone Miner Res
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2009
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1.29
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19
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Nephroblastoma overexpressed (Nov) inhibits osteoblastogenesis and causes osteopenia.
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J Biol Chem
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2007
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1.28
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20
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Genetic dissection of mouse distal chromosome 1 reveals three linked BMD QTLs with sex-dependent regulation of bone phenotypes.
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J Bone Miner Res
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2007
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1.26
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21
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Effects of cortisol and bone morphogenetic protein-2 on stromal cell differentiation: correlation with CCAAT-enhancer binding protein expression.
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1.22
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22
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CCAAT/enhancer binding protein homologous protein (DDIT3) induces osteoblastic cell differentiation.
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1.21
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23
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Drug-induced osteoporosis: mechanisms and clinical implications.
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Am J Med
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1.15
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24
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CCAAT/Enhancer-binding protein homologous protein (CHOP) decreases bone formation and causes osteopenia.
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Bone
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2006
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1.14
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25
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Misexpression of CCAAT/enhancer binding protein beta causes osteopenia.
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J Endocrinol
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2009
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1.14
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26
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Conditional deletion of gremlin causes a transient increase in bone formation and bone mass.
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J Biol Chem
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2007
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1.12
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27
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Skeletal overexpression of connective tissue growth factor impairs bone formation and causes osteopenia.
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Endocrinology
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2008
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1.08
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28
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Notch regulation of bone development and remodeling and related skeletal disorders.
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Calcif Tissue Int
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1.05
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29
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Connective tissue growth factor enhances osteoblastogenesis in vitro.
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J Biol Chem
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1.02
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30
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The heparin-binding domain of IGFBP-2 has insulin-like growth factor binding-independent biologic activity in the growing skeleton.
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J Biol Chem
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2011
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1.02
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31
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Notch signaling in skeletal health and disease.
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Eur J Endocrinol
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1.00
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32
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Reciprocal regulation of Notch and nuclear factor of activated T-cells (NFAT) c1 transactivation in osteoblasts.
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J Biol Chem
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2010
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0.99
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33
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C/EBP homologous protein is necessary for normal osteoblastic function.
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J Cell Biochem
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2006
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0.99
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34
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A novel spontaneous mutation of Irs1 in mice results in hyperinsulinemia, reduced growth, low bone mass and impaired adipogenesis.
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J Endocrinol
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2009
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0.97
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35
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Cortisol regulates the expression of Notch in osteoblasts.
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J Cell Biochem
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2002
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0.97
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36
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AU-rich elements in the collagenase 3 mRNA mediate stabilization of the transcript by cortisol in osteoblasts.
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J Biol Chem
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2003
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0.95
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37
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The mutation ROR2W749X, linked to human BDB, is a recessive mutation in the mouse, causing brachydactyly, mediating patterning of joints and modeling recessive Robinow syndrome.
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Development
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2008
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0.92
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38
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HES1 (hairy and enhancer of split 1) is a determinant of bone mass.
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J Biol Chem
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0.92
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39
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Bone loss or lost bone: rationale and recommendations for the diagnosis and treatment of early postmenopausal bone loss.
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Curr Osteoporos Rep
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2009
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0.91
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Effects of activated T cells on osteoclastogenesis depend on how they are activated.
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Bone
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0.90
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41
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Twisted gastrulation, a bone morphogenetic protein agonist/antagonist, is not required for post-natal skeletal function.
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Bone
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2006
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0.90
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42
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Activated alveolar epithelial cells initiate fibrosis through autocrine and paracrine secretion of connective tissue growth factor.
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Am J Physiol Lung Cell Mol Physiol
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Glucocorticoid-induced osteoporosis in rheumatic diseases.
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Clinics (Sao Paulo)
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Nuclear factor of activated T-cells (NFAT)C2 inhibits Notch receptor signaling in osteoblasts.
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J Biol Chem
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2012
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0.86
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45
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Overexpression of twisted gastrulation inhibits bone morphogenetic protein action and prevents osteoblast cell differentiation in vitro.
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Endocrinology
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2005
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0.86
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46
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Notch suppresses nuclear factor of activated T cells (NFAT) transactivation and Nfatc1 expression in chondrocytes.
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Endocrinology
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47
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Gene delivery by retroviruses.
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Methods Mol Biol
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2008
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48
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BMD regulation on mouse distal chromosome 1, candidate genes, and response to ovariectomy or dietary fat.
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J Bone Miner Res
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2011
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0.84
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49
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Hairy and Enhancer of Split-related with YRPW motif (HEY)2 regulates bone remodeling in mice.
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J Biol Chem
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2013
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50
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Activation of the ERK pathway in osteoblastic cells, role of gremlin and BMP-2.
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J Cell Biochem
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2008
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0.82
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51
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Loss of gremlin delays primordial follicle assembly but does not affect female fertility in mice.
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Biol Reprod
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2011
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0.81
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52
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Bone morphogenetic protein-2 suppresses collagenase-3 promoter activity in osteoblasts through a runt domain factor 2 binding site.
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J Cell Physiol
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53
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Col3.6-HSD2 transgenic mice: a glucocorticoid loss-of-function model spanning early and late osteoblast differentiation.
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Bone
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54
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Deficiency of Sef is associated with increased postnatal cortical bone mass by regulating Runx2 activity.
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J Bone Miner Res
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55
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Role of the RAM domain and ankyrin repeats on notch signaling and activity in cells of osteoblastic lineage.
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J Bone Miner Res
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2006
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0.80
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56
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Activation of Nfatc2 in osteoblasts causes osteopenia.
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Nemo-like kinase inhibits osteoblastogenesis by suppressing bone morphogenetic protein and WNT canonical signaling.
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Management of glucocorticoid induced osteoporosis in premenopausal women with autoimmune disease.
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Autoimmun Rev
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Glucocorticoid-induced osteoporosis: clinical and therapeutic aspects.
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Transcriptional regulation of collagenase-3 by interleukin-1 alpha in osteoblasts.
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61
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Nephroblastoma overexpressed (Nov) induces gremlin in ST-2 stromal cell lines by post-transcriptional mechanisms.
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Transgenic overexpression of gremlin results in developmental defects in enamel and dentin in mice.
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Connect Tissue Res
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65
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66
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Cortisol Enhances the Expression of mac25/Insulin-Like Growth Factor-Binding Protein-Related Protein-1 in Cultured Osteoblasts* *This work was supported by NIDDK Grant DK-45227 and a scholarship (to R.C.P.) from Fundação Coordenação de Aperfeiçoa mento de Pessoal de Nível Superior (CAPES), Universidade de São Paulo (São Paulo, Brazil).
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Bone Morphogenetic Proteins Induce Gremlin, a Protein That Limits Their Activity in Osteoblasts* *This work was supported by NIAMSD Grant AR-21707.
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Endocrinology
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2000
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