Published in J Biol Chem on November 19, 2012
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Connective tissue growth factor is a target of notch signaling in cells of the osteoblastic lineage. Bone (2014) 0.80
NFAT signaling in osteoblasts regulates the hematopoietic niche in the bone microenvironment. Clin Dev Immunol (2013) 0.79
Activation of Nfatc2 in osteoblasts causes osteopenia. J Cell Physiol (2015) 0.79
Hairy and Enhancer of Split-related with YRPW Motif-Like (HeyL) is Dispensable for Bone Remodeling in Mice. J Cell Biochem (2016) 0.75
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NFAT restricts osteochondroma formation from entheseal progenitors. JCI Insight (2016) 0.75
Parathyroid hormone inhibits notch signaling in osteoblasts and osteocytes. Bone (2017) 0.75
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HES and HERP families: multiple effectors of the Notch signaling pathway. J Cell Physiol (2003) 7.32
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Independent signals control expression of the calcineurin inhibitory proteins MCIP1 and MCIP2 in striated muscles. Circ Res (2000) 3.04
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Notch activation stimulates transient and selective binding of Su(H)/CSL to target enhancers. Genes Dev (2007) 2.19
Housekeeping and tissue-specific genes in mouse tissues. BMC Genomics (2007) 2.06
Comparative analysis of the human and mouse Hey1 promoter: Hey genes are new Notch target genes. Biochem Biophys Res Commun (2000) 2.06
Effect of primary and secondary structure of oligodeoxyribonucleotides on the fluorescent properties of conjugated dyes. Nucleic Acids Res (2002) 1.98
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Calcineurin/NFAT signaling in osteoblasts regulates bone mass. Dev Cell (2006) 1.95
HERP, a new primary target of Notch regulated by ligand binding. Mol Cell Biol (2001) 1.85
The role of modulatory calcineurin-interacting proteins in calcineurin signaling. Trends Cardiovasc Med (2003) 1.80
A simple and sensitive histochemical method for calcium. Proc Soc Exp Biol Med (1952) 1.78
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More complicated than it looks: assembly of Notch pathway transcription complexes. Oncogene (2008) 1.48
The vitamin D receptor, Runx2, and the Notch signaling pathway cooperate in the transcriptional regulation of osteopontin. J Biol Chem (2005) 1.38
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CCAAT/enhancer binding protein homologous protein (DDIT3) induces osteoblastic cell differentiation. Endocrinology (2003) 1.21
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Calcineurin regulates bone formation by the osteoblast. Proc Natl Acad Sci U S A (2005) 1.16
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NFATc1 mediates HDAC-dependent transcriptional repression of osteocalcin expression during osteoblast differentiation. Bone (2009) 1.11
HERP1 is a cell type-specific primary target of Notch. J Biol Chem (2001) 1.08
Transcriptional regulation of bone and joint remodeling by NFAT. Immunol Rev (2010) 1.06
Conditional disruption of calcineurin B1 in osteoblasts increases bone formation and reduces bone resorption. J Biol Chem (2007) 1.01
Reciprocal regulation of Notch and nuclear factor of activated T-cells (NFAT) c1 transactivation in osteoblasts. J Biol Chem (2010) 0.99
Cortisol regulates the expression of Notch in osteoblasts. J Cell Biochem (2002) 0.97
Signals that determine the fate of osteoblastic cells. J Endocrinol Invest (2005) 0.96
AU-rich elements in the collagenase 3 mRNA mediate stabilization of the transcript by cortisol in osteoblasts. J Biol Chem (2003) 0.95
Age-related changes in trabecular architecture differ in female and male C57BL/6J mice. J Bone Miner Res (2007) 3.38
Growth hormone, insulin-like growth factors, and the skeleton. Endocr Rev (2008) 2.64
Bone morphogenetic proteins and their antagonists. Rev Endocr Metab Disord (2006) 2.03
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Notch inhibits osteoblast differentiation and causes osteopenia. Endocrinology (2008) 1.78
Notch 1 overexpression inhibits osteoblastogenesis by suppressing Wnt/beta-catenin but not bone morphogenetic protein signaling. J Biol Chem (2006) 1.61
Skeletal overexpression of gremlin impairs bone formation and causes osteopenia. Endocrinology (2004) 1.58
Notch 1 impairs osteoblastic cell differentiation. Endocrinology (2003) 1.57
PPARG by dietary fat interaction influences bone mass in mice and humans. J Bone Miner Res (2008) 1.50
Notch and the skeleton. Mol Cell Biol (2009) 1.49
A soluble bone morphogenetic protein type IA receptor increases bone mass and bone strength. Proc Natl Acad Sci U S A (2012) 1.48
A soluble activin type IIA receptor induces bone formation and improves skeletal integrity. Proc Natl Acad Sci U S A (2008) 1.42
Infrared analysis of the mineral and matrix in bones of osteonectin-null mice and their wildtype controls. J Bone Miner Res (2003) 1.39
The ternary IGF complex influences postnatal bone acquisition and the skeletal response to intermittent parathyroid hormone. J Endocrinol (2006) 1.37
Osteonectin-null mutation compromises osteoblast formation, maturation, and survival. Endocrinology (2003) 1.37
The fate of circulating osteoblasts. N Engl J Med (2005) 1.36
Expression and regulation of CCN genes in murine osteoblasts. Bone (2005) 1.32
Serum IGF-1 determines skeletal strength by regulating subperiosteal expansion and trait interactions. J Bone Miner Res (2009) 1.29
Nephroblastoma overexpressed (Nov) inhibits osteoblastogenesis and causes osteopenia. J Biol Chem (2007) 1.28
Genetic dissection of mouse distal chromosome 1 reveals three linked BMD QTLs with sex-dependent regulation of bone phenotypes. J Bone Miner Res (2007) 1.26
Effects of cortisol and bone morphogenetic protein-2 on stromal cell differentiation: correlation with CCAAT-enhancer binding protein expression. Bone (2002) 1.22
CCAAT/enhancer binding protein homologous protein (DDIT3) induces osteoblastic cell differentiation. Endocrinology (2003) 1.21
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CCAAT/Enhancer-binding protein homologous protein (CHOP) decreases bone formation and causes osteopenia. Bone (2006) 1.14
Misexpression of CCAAT/enhancer binding protein beta causes osteopenia. J Endocrinol (2009) 1.14
Conditional deletion of gremlin causes a transient increase in bone formation and bone mass. J Biol Chem (2007) 1.12
Skeletal overexpression of connective tissue growth factor impairs bone formation and causes osteopenia. Endocrinology (2008) 1.08
Notch regulation of bone development and remodeling and related skeletal disorders. Calcif Tissue Int (2011) 1.05
The heparin-binding domain of IGFBP-2 has insulin-like growth factor binding-independent biologic activity in the growing skeleton. J Biol Chem (2011) 1.02
Connective tissue growth factor enhances osteoblastogenesis in vitro. J Biol Chem (2008) 1.02
Connective tissue growth factor is required for skeletal development and postnatal skeletal homeostasis in male mice. Endocrinology (2010) 1.02
Notch signaling in skeletal health and disease. Eur J Endocrinol (2013) 1.00
Reciprocal regulation of Notch and nuclear factor of activated T-cells (NFAT) c1 transactivation in osteoblasts. J Biol Chem (2010) 0.99
C/EBP homologous protein is necessary for normal osteoblastic function. J Cell Biochem (2006) 0.99
Cortisol regulates the expression of Notch in osteoblasts. J Cell Biochem (2002) 0.97
Nephroblastoma overexpressed (Nov) inactivation sensitizes osteoblasts to bone morphogenetic protein-2, but nov is dispensable for skeletal homeostasis. Endocrinology (2009) 0.97
A novel spontaneous mutation of Irs1 in mice results in hyperinsulinemia, reduced growth, low bone mass and impaired adipogenesis. J Endocrinol (2009) 0.97
AU-rich elements in the collagenase 3 mRNA mediate stabilization of the transcript by cortisol in osteoblasts. J Biol Chem (2003) 0.95
HES1 (hairy and enhancer of split 1) is a determinant of bone mass. J Biol Chem (2010) 0.92
The mutation ROR2W749X, linked to human BDB, is a recessive mutation in the mouse, causing brachydactyly, mediating patterning of joints and modeling recessive Robinow syndrome. Development (2008) 0.92
Bone loss or lost bone: rationale and recommendations for the diagnosis and treatment of early postmenopausal bone loss. Curr Osteoporos Rep (2009) 0.91
Effects of activated T cells on osteoclastogenesis depend on how they are activated. Bone (2004) 0.90
Twisted gastrulation, a bone morphogenetic protein agonist/antagonist, is not required for post-natal skeletal function. Bone (2006) 0.90
Radiographic and clinical outcome in early juvenile rheumatoid arthritis and juvenile spondyloarthropathy: a 3-year prospective study. J Rheumatol (2006) 0.89
Activated alveolar epithelial cells initiate fibrosis through autocrine and paracrine secretion of connective tissue growth factor. Am J Physiol Lung Cell Mol Physiol (2014) 0.88
Juvenile psoriatic arthritis: longterm outcome and differentiation from other subtypes of juvenile idiopathic arthritis. J Rheumatol (2009) 0.87
Glucocorticoid-induced osteoporosis in rheumatic diseases. Clinics (Sao Paulo) (2010) 0.87
Notch suppresses nuclear factor of activated T cells (NFAT) transactivation and Nfatc1 expression in chondrocytes. Endocrinology (2012) 0.86
Overexpression of twisted gastrulation inhibits bone morphogenetic protein action and prevents osteoblast cell differentiation in vitro. Endocrinology (2005) 0.86
Gene delivery by retroviruses. Methods Mol Biol (2008) 0.85
BMD regulation on mouse distal chromosome 1, candidate genes, and response to ovariectomy or dietary fat. J Bone Miner Res (2011) 0.84
Hairy and Enhancer of Split-related with YRPW motif (HEY)2 regulates bone remodeling in mice. J Biol Chem (2013) 0.82
Activation of the ERK pathway in osteoblastic cells, role of gremlin and BMP-2. J Cell Biochem (2008) 0.82
Col3.6-HSD2 transgenic mice: a glucocorticoid loss-of-function model spanning early and late osteoblast differentiation. Bone (2010) 0.81
Bone morphogenetic protein-2 suppresses collagenase-3 promoter activity in osteoblasts through a runt domain factor 2 binding site. J Cell Physiol (2005) 0.81
Loss of gremlin delays primordial follicle assembly but does not affect female fertility in mice. Biol Reprod (2011) 0.81
Deficiency of Sef is associated with increased postnatal cortical bone mass by regulating Runx2 activity. J Bone Miner Res (2014) 0.81
Role of the RAM domain and ankyrin repeats on notch signaling and activity in cells of osteoblastic lineage. J Bone Miner Res (2006) 0.80
Nemo-like kinase inhibits osteoblastogenesis by suppressing bone morphogenetic protein and WNT canonical signaling. J Cell Biochem (2012) 0.79
Activation of Nfatc2 in osteoblasts causes osteopenia. J Cell Physiol (2015) 0.79
Mannose-binding lectin deficiency is associated with early onset of polyarticular juvenile rheumatoid arthritis: a cohort study. Arthritis Res Ther (2008) 0.78
Management of glucocorticoid induced osteoporosis in premenopausal women with autoimmune disease. Autoimmun Rev (2003) 0.78
Glucocorticoid-induced osteoporosis: clinical and therapeutic aspects. Arq Bras Endocrinol Metabol (2007) 0.78
Transcriptional regulation of collagenase-3 by interleukin-1 alpha in osteoblasts. J Cell Biochem (2003) 0.76
11beta-hydroxysteroid dehydrogenase, an amplifier of glucocorticoid action in osteoblasts. J Bone Miner Res (2002) 0.76
Treatment of glucocorticoid-induced osteoporsis. Ther Adv Musculoskelet Dis (2009) 0.76
Nephroblastoma overexpressed (Nov) induces gremlin in ST-2 stromal cell lines by post-transcriptional mechanisms. J Cell Biochem (2011) 0.76
Connective tissue growth factor (CTGF) transactivates nuclear factor of activated T-cells (NFAT) in cells of the osteoblastic lineage. J Cell Biochem (2010) 0.75
Transgenic overexpression of gremlin results in developmental defects in enamel and dentin in mice. Connect Tissue Res (2008) 0.75
Bone Morphogenetic Proteins Induce Gremlin, a Protein That Limits Their Activity in Osteoblasts* *This work was supported by NIAMSD Grant AR-21707. Endocrinology (2000) 0.75