Published in Am J Physiol Lung Cell Mol Physiol on February 07, 2014
CTGF upregulation correlates with MMP-9 level in airway remodeling in a murine model of asthma. Arch Med Sci (2016) 0.77
Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3. Cell (1996) 6.52
The global burden of asthma. Chest (2006) 5.74
Tumor imaging by means of proteolytic activation of cell-penetrating peptides. Proc Natl Acad Sci U S A (2004) 4.95
Immunology of asthma and chronic obstructive pulmonary disease. Nat Rev Immunol (2008) 4.89
Subepithelial fibrosis in the bronchi of asthmatics. Lancet (1989) 3.70
Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival. Proc Natl Acad Sci U S A (2010) 3.41
Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases. Proc Natl Acad Sci U S A (2010) 3.03
Pathogenesis of asthma. Clin Exp Allergy (2008) 2.93
Prominent neutrophilic inflammation in sputum from subjects with asthma exacerbation. J Allergy Clin Immunol (1995) 2.88
Decreased allergic lung inflammatory cell egression and increased susceptibility to asphyxiation in MMP2-deficiency. Nat Immunol (2002) 2.83
In vivo characterization of activatable cell penetrating peptides for targeting protease activity in cancer. Integr Biol (Camb) (2009) 2.30
Increased matrix metalloproteinase-9 in the airway after allergen challenge. Am J Respir Crit Care Med (2000) 2.18
Matrix metalloproteinases in lung: multiple, multifarious, and multifaceted. Physiol Rev (2007) 2.14
Systemic in vivo distribution of activatable cell penetrating peptides is superior to that of cell penetrating peptides. Integr Biol (Camb) (2009) 1.78
Immunologic and inflammatory mechanisms that drive asthma progression to remodeling. J Allergy Clin Immunol (2008) 1.71
Extravascular fibrin, plasminogen activator, plasminogen activator inhibitors, and airway hyperresponsiveness. J Clin Invest (2004) 1.70
Overlapping and independent contributions of MMP2 and MMP9 to lung allergic inflammatory cell egression through decreased CC chemokines. FASEB J (2004) 1.64
Role of matrix metalloproteinases in delayed neuronal damage after transient global cerebral ischemia. J Neurosci (2004) 1.56
Real-time in vivo molecular detection of primary tumors and metastases with ratiometric activatable cell-penetrating peptides. Cancer Res (2012) 1.50
Matrix metalloproteinase-9 deficiency results in enhanced allergen-induced airway inflammation. J Immunol (2004) 1.49
Reduced peribronchial fibrosis in allergen-challenged MMP-9-deficient mice. Am J Physiol Lung Cell Mol Physiol (2006) 1.46
Matrix metalloproteinase-9 deficiency impairs cellular infiltration and bronchial hyperresponsiveness during allergen-induced airway inflammation. Am J Pathol (2002) 1.45
Real-time assessment of inflammation and treatment response in a mouse model of allergic airway inflammation. J Clin Invest (2008) 1.43
Tenascin is increased in airway basement membrane of asthmatics and decreased by an inhaled steroid. Am J Respir Crit Care Med (1997) 1.39
Inhibition of matrix metalloproteinases prevents allergen-induced airway inflammation in a murine model of asthma. J Immunol (1999) 1.38
MMP-2- and MMP-9-linked gelatinolytic activity in the sputum from patients with asthma and chronic obstructive pulmonary disease. Int Arch Allergy Immunol (2000) 1.33
Thrombin in the airways of asthmatic patients. Lung (1999) 1.28
Anti-inflammatory mechanism of simvastatin in mouse allergic asthma model. Eur J Pharmacol (2006) 1.28
Matrix metalloproteinases in asthma and COPD. Curr Opin Pharmacol (2005) 1.27
Proteomic identification of in vivo substrates for matrix metalloproteinases 2 and 9 reveals a mechanism for resolution of inflammation. J Immunol (2006) 1.27
The relationship of reticular basement membrane thickness to airway wall remodeling in asthma. Am J Respir Crit Care Med (2002) 1.20
Neutrophil-derived matrix metalloproteinase-9 is increased in severe asthma and poorly inhibited by glucocorticoids. J Allergy Clin Immunol (2003) 1.19
92-kd gelatinase is actively expressed by eosinophils and stored by neutrophils in squamous cell carcinoma. Am J Pathol (1993) 1.18
Assays of matrix metalloproteinases (MMPs) activities: a review. Biochimie (2005) 1.17
Thrombin activity associated with neuronal damage during acute focal ischemia. J Neurosci (2012) 1.13
In vivo fluorescence imaging of atherosclerotic plaques with activatable cell-penetrating peptides targeting thrombin activity. Integr Biol (Camb) (2012) 1.11
Pathogenesis of allergic airway inflammation. Curr Allergy Asthma Rep (2010) 1.11
αVβ3 integrin regulates macrophage inflammatory responses via PI3 kinase/Akt-dependent NF-κB activation. J Cell Physiol (2011) 1.09
CD4+ cells are required for chronic eosinophilic lung inflammation but not airway remodeling. Am J Physiol Lung Cell Mol Physiol (2008) 1.07
Parallel in vivo and in vitro selection using phage display identifies protease-dependent tumor-targeting peptides. J Biol Chem (2010) 1.03
Images in allergy and immunology: neutrophils in asthma. J Allergy Clin Immunol (2007) 1.02
Ratiometric activatable cell-penetrating peptides provide rapid in vivo readout of thrombin activation. Angew Chem Int Ed Engl (2012) 1.00
Human eosinophils release matrix metalloproteinase-9 on stimulation with TNF-alpha. J Allergy Clin Immunol (1999) 0.94
Vascular expression of the alpha(v)beta(3)-integrin in lung and other organs. Am J Physiol Lung Cell Mol Physiol (2000) 0.89
A role for decorin in a murine model of allergen-induced asthma. Am J Physiol Lung Cell Mol Physiol (2011) 0.87
Quantification of collagen and proteoglycan deposition in a murine model of airway remodelling. Respir Res (2005) 0.87
Specific allergens enhance elastase release in stimulated neutrophils from asthmatic patients. Int Arch Allergy Immunol (2003) 0.84
Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein. Nat Biotechnol (2004) 36.25
A monomeric red fluorescent protein. Proc Natl Acad Sci U S A (2002) 21.56
Partitioning of lipid-modified monomeric GFPs into membrane microdomains of live cells. Science (2002) 18.89
A guide to choosing fluorescent proteins. Nat Methods (2005) 18.55
The fluorescent toolbox for assessing protein location and function. Science (2006) 14.02
Creating new fluorescent probes for cell biology. Nat Rev Mol Cell Biol (2002) 9.25
Improving the photostability of bright monomeric orange and red fluorescent proteins. Nat Methods (2008) 8.41
New biarsenical ligands and tetracysteine motifs for protein labeling in vitro and in vivo: synthesis and biological applications. J Am Chem Soc (2002) 5.83
Multicolor and electron microscopic imaging of connexin trafficking. Science (2002) 5.60
Investigating mitochondrial redox potential with redox-sensitive green fluorescent protein indicators. J Biol Chem (2004) 5.26
Tumor imaging by means of proteolytic activation of cell-penetrating peptides. Proc Natl Acad Sci U S A (2004) 4.95
Imaging dynamic redox changes in mammalian cells with green fluorescent protein indicators. J Biol Chem (2004) 4.75
Characterization of engineered channelrhodopsin variants with improved properties and kinetics. Biophys J (2009) 4.75
Mammalian expression of infrared fluorescent proteins engineered from a bacterial phytochrome. Science (2009) 4.67
Novel chromophores and buried charges control color in mFruits. Biochemistry (2006) 4.64
Visualizing the mechanical activation of Src. Nature (2005) 4.63
Ca2+ indicators based on computationally redesigned calmodulin-peptide pairs. Chem Biol (2006) 4.52
Bcl-2-mediated alterations in endoplasmic reticulum Ca2+ analyzed with an improved genetically encoded fluorescent sensor. Proc Natl Acad Sci U S A (2004) 4.46
A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C. J Cell Biol (2003) 4.38
Evolution of new nonantibody proteins via iterative somatic hypermutation. Proc Natl Acad Sci U S A (2004) 4.37
A genetically encoded tag for correlated light and electron microscopy of intact cells, tissues, and organisms. PLoS Biol (2011) 4.07
Measuring calcium signaling using genetically targetable fluorescent indicators. Nat Protoc (2006) 3.96
Activity-dependent regulation of dendritic synthesis and trafficking of AMPA receptors. Nat Neurosci (2004) 3.64
Improving FRET dynamic range with bright green and red fluorescent proteins. Nat Methods (2012) 3.54
Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival. Proc Natl Acad Sci U S A (2010) 3.41
Mammalian cell-based optimization of the biarsenical-binding tetracysteine motif for improved fluorescence and affinity. Nat Biotechnol (2005) 3.28
Imaging tri-fusion multimodality reporter gene expression in living subjects. Cancer Res (2004) 3.16
A FlAsH-based FRET approach to determine G protein-coupled receptor activation in living cells. Nat Methods (2005) 3.11
Autofluorescent proteins with excitation in the optical window for intravital imaging in mammals. Chem Biol (2009) 3.11
Fluorescence-guided surgery with live molecular navigation--a new cutting edge. Nat Rev Cancer (2013) 3.08
Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases. Proc Natl Acad Sci U S A (2010) 3.03
ReaChR: a red-shifted variant of channelrhodopsin enables deep transcranial optogenetic excitation. Nat Neurosci (2013) 2.98
Insulin disrupts beta-adrenergic signalling to protein kinase A in adipocytes. Nature (2005) 2.54
Calcium Green FlAsH as a genetically targeted small-molecule calcium indicator. Nat Chem Biol (2007) 2.47
Single-spike detection in vitro and in vivo with a genetic Ca2+ sensor. Nat Methods (2008) 2.44
Optically monitoring voltage in neurons by photo-induced electron transfer through molecular wires. Proc Natl Acad Sci U S A (2012) 2.35
All-optical histology using ultrashort laser pulses. Neuron (2003) 2.33
BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress. Mol Cell (2004) 2.32
In vivo characterization of activatable cell penetrating peptides for targeting protease activity in cancer. Integr Biol (Camb) (2009) 2.30
Exploration of new chromophore structures leads to the identification of improved blue fluorescent proteins. Biochemistry (2007) 2.23
Functional fluorescent Ca2+ indicator proteins in transgenic mice under TET control. PLoS Biol (2004) 2.20
Optogenetic inhibition of synaptic release with chromophore-assisted light inactivation (CALI). Neuron (2013) 2.16
Overview of the Alliance for Cellular Signaling. Nature (2002) 2.15
Aptamers switch on fluorescence of triphenylmethane dyes. J Am Chem Soc (2003) 2.05
Spatio-temporal dynamics of protein kinase B/Akt signaling revealed by a genetically encoded fluorescent reporter. J Biol Chem (2004) 1.96
Genetically targeted chromophore-assisted light inactivation. Nat Biotechnol (2003) 1.90
Photoswitching mechanism of cyanine dyes. J Am Chem Soc (2009) 1.86
A new form of cerebellar long-term potentiation is postsynaptic and depends on nitric oxide but not cAMP. Proc Natl Acad Sci U S A (2002) 1.85
Optical measurement of synaptic glutamate spillover and reuptake by linker optimized glutamate-sensitive fluorescent reporters. Proc Natl Acad Sci U S A (2008) 1.80
Systemic in vivo distribution of activatable cell penetrating peptides is superior to that of cell penetrating peptides. Integr Biol (Camb) (2009) 1.78
Golgi twins in late mitosis revealed by genetically encoded tags for live cell imaging and correlated electron microscopy. Proc Natl Acad Sci U S A (2006) 1.78
Fluorescent peptides highlight peripheral nerves during surgery in mice. Nat Biotechnol (2011) 1.73
Photo-inducible cell ablation in Caenorhabditis elegans using the genetically encoded singlet oxygen generating protein miniSOG. Proc Natl Acad Sci U S A (2012) 1.72
Imaging of cAMP levels and protein kinase A activity reveals that retinal waves drive oscillations in second-messenger cascades. J Neurosci (2006) 1.67
Control of mammalian translation by mRNA structure near caps. RNA (2006) 1.66
Fluorescent and photo-oxidizing TimeSTAMP tags track protein fates in light and electron microscopy. Nat Neurosci (2012) 1.60
Systems analysis of PKA-mediated phosphorylation gradients in live cardiac myocytes. Proc Natl Acad Sci U S A (2006) 1.59
Calcium-dependent regulation of protein kinase D revealed by a genetically encoded kinase activity reporter. J Biol Chem (2006) 1.56
Diverse small-molecule modulators of SMN expression found by high-throughput compound screening: early leads towards a therapeutic for spinal muscular atrophy. Hum Mol Genet (2005) 1.52
A hexahistidine-Zn2+-dye label reveals STIM1 surface exposure. Proc Natl Acad Sci U S A (2007) 1.52
Real-time in vivo molecular detection of primary tumors and metastases with ratiometric activatable cell-penetrating peptides. Cancer Res (2012) 1.50
Simultaneous visualization of protumorigenic Src and MT1-MMP activities with fluorescence resonance energy transfer. Cancer Res (2010) 1.50
Reversing cerebellar long-term depression. Proc Natl Acad Sci U S A (2003) 1.33
Preparation of the membrane-permeant biarsenicals FlAsH-EDT2 and ReAsH-EDT2 for fluorescent labeling of tetracysteine-tagged proteins. Nat Protoc (2008) 1.31
A drug-controllable tag for visualizing newly synthesized proteins in cells and whole animals. Proc Natl Acad Sci U S A (2008) 1.29
Fluorescent labeling of tetracysteine-tagged proteins in intact cells. Nat Protoc (2010) 1.28
Isoform-specific PKA dynamics revealed by dye-triggered aggregation and DAKAP1alpha-mediated localization in living cells. Chem Biol (2007) 1.23
A structural basis for the assembly and functions of a viral polymer that inactivates multiple tumor suppressors. Cell (2012) 1.23
Temperature-sensitive dendritic micelles. J Am Chem Soc (2005) 1.18
Hairpin structure of a biarsenical-tetracysteine motif determined by NMR spectroscopy. J Am Chem Soc (2009) 1.16
Gibberellins accumulate in the elongating endodermal cells of Arabidopsis root. Proc Natl Acad Sci U S A (2013) 1.16
Fluorescence imaging in surgery. IEEE Rev Biomed Eng (2013) 1.14
Thrombin activity associated with neuronal damage during acute focal ischemia. J Neurosci (2012) 1.13
Novel fluorogenic substrates for imaging beta-lactamase gene expression. J Am Chem Soc (2003) 1.11
In vivo fluorescence imaging of atherosclerotic plaques with activatable cell-penetrating peptides targeting thrombin activity. Integr Biol (Camb) (2012) 1.11
Fast 18F labeling of a near-infrared fluorophore enables positron emission tomography and optical imaging of sentinel lymph nodes. Bioconjug Chem (2010) 1.11
In vivo quantitative proteomics of somatosensory cortical synapses shows which protein levels are modulated by sensory deprivation. Proc Natl Acad Sci U S A (2013) 1.09
Evolving proteins in mammalian cells using somatic hypermutation. Nat Protoc (2006) 1.07
Detection of calcium transients in Drosophila mushroom body neurons with camgaroo reporters. J Neurosci (2003) 1.05
Molecular biology and mutation of green fluorescent protein. Methods Biochem Anal (2006) 1.04
Parallel in vivo and in vitro selection using phage display identifies protease-dependent tumor-targeting peptides. J Biol Chem (2010) 1.03
Dynamics of the upper 50-kDa domain of myosin V examined with fluorescence resonance energy transfer. J Biol Chem (2005) 1.02
Indicators based on fluorescence resonance energy transfer (FRET). Cold Spring Harb Protoc (2009) 1.01
In vivo targeting of hydrogen peroxide by activatable cell-penetrating peptides. J Am Chem Soc (2014) 1.00
Ratiometric activatable cell-penetrating peptides provide rapid in vivo readout of thrombin activation. Angew Chem Int Ed Engl (2012) 1.00
Bhc-cNMPs as either water-soluble or membrane-permeant photoreleasable cyclic nucleotides for both one- and two-photon excitation. Chembiochem (2004) 0.96
Fluorescence patterns from supramolecular polymer assembly and disassembly for sensing metallo- and nonmetalloproteins. J Am Chem Soc (2009) 0.95
Concurrent imaging of synaptic vesicle recycling and calcium dynamics. Front Mol Neurosci (2011) 0.95
Improved facial nerve identification with novel fluorescently labeled probe. Laryngoscope (2011) 0.95
Neuroligin trafficking deficiencies arising from mutations in the alpha/beta-hydrolase fold protein family. J Biol Chem (2010) 0.95
Improved PeT molecules for optically sensing voltage in neurons. J Am Chem Soc (2015) 0.93
Dendrimeric micelles for controlled drug release and targeted delivery. Mol Pharm (2005) 0.91
Tetracysteine genetic tags complexed with biarsenical ligands as a tool for investigating gap junction structure and dynamics. Cell Commun Adhes (2003) 0.91
Selective sensing of metalloproteins from nonselective binding using a fluorogenic amphiphilic polymer. J Am Chem Soc (2006) 0.89
Dual-porosity hollow nanoparticles for the immunoprotection and delivery of nonhuman enzymes. Nano Lett (2014) 0.87
Early detection of thrombin activity in neuroinflammatory disease. Ann Neurol (2014) 0.87
Polymeric inverse micelles as selective peptide extraction agents for MALDI-MS analysis. Anal Chem (2007) 0.83
The 2009 Lindau Nobel Laureate Meeting: Roger Y. Tsien, Chemistry 2008. J Vis Exp (2010) 0.82