Published in J Immunol on February 15, 2004
Matrix metalloproteinases and the regulation of tissue remodelling. Nat Rev Mol Cell Biol (2007) 10.17
Resolution of airway inflammation and hyperreactivity after in vivo transfer of CD4+CD25+ regulatory T cells is interleukin 10 dependent. J Exp Med (2005) 3.48
Metalloproteinases and their inhibitors: regulators of wound healing. Int J Biochem Cell Biol (2007) 2.65
Matrix metalloproteinases as modulators of inflammation. Semin Cell Dev Biol (2007) 2.14
Matrix metalloproteinases in lung: multiple, multifarious, and multifaceted. Physiol Rev (2007) 2.14
Role for matrix metalloproteinase 9 in granuloma formation during pulmonary Mycobacterium tuberculosis infection. Infect Immun (2006) 1.75
Peptide immunotherapy in allergic asthma generates IL-10-dependent immunological tolerance associated with linked epitope suppression. J Exp Med (2009) 1.73
Resolution of allergic inflammation and airway hyperreactivity is dependent upon disruption of the T1/ST2-IL-33 pathway. Am J Respir Crit Care Med (2009) 1.72
Altered lymphocyte trafficking and diminished airway reactivity in transgenic mice expressing human MMP-9 in a mouse model of asthma. Am J Physiol Lung Cell Mol Physiol (2009) 1.48
IL-13Ralpha2 and IL-10 coordinately suppress airway inflammation, airway-hyperreactivity, and fibrosis in mice. J Clin Invest (2007) 1.47
Matrix metalloproteinase-9: Many shades of function in cardiovascular disease. Physiology (Bethesda) (2013) 1.41
Nitric oxide promotes airway epithelial wound repair through enhanced activation of MMP-9. Am J Respir Cell Mol Biol (2006) 1.27
Proteomic identification of in vivo substrates for matrix metalloproteinases 2 and 9 reveals a mechanism for resolution of inflammation. J Immunol (2006) 1.27
Eosinophils in the pathogenesis of allergic airways disease. Cell Mol Life Sci (2007) 1.26
Divergent functions for airway epithelial matrix metalloproteinase 7 and retinoic acid in experimental asthma. Nat Immunol (2009) 1.25
Chronic inflammation and asthma. Mutat Res (2009) 1.22
Pathogenesis of allergic airway inflammation. Curr Allergy Asthma Rep (2010) 1.11
A TLR2 agonist in German cockroach frass activates MMP-9 release and is protective against allergic inflammation in mice. J Immunol (2009) 1.04
Strain and model dependent differences in inflammatory cell recruitment in mice. Inflamm Res (2008) 1.04
Reproducibility of a novel model of murine asthma-like pulmonary inflammation. Clin Exp Immunol (2004) 1.02
FXR protects lung from lipopolysaccharide-induced acute injury. Mol Endocrinol (2011) 1.00
MMP-9 gene variants increase the risk for non-atopic asthma in children. Respir Res (2010) 0.95
Matrix metalloproteinase-9 deficiency leads to prolonged foreign body response in the brain associated with increased IL-1beta levels and leakage of the blood-brain barrier. Matrix Biol (2009) 0.91
Genetically manipulated mouse models of lung disease: potential and pitfalls. Am J Physiol Lung Cell Mol Physiol (2011) 0.90
Plasminogen is an important regulator in the pathogenesis of a murine model of asthma. Am J Respir Crit Care Med (2007) 0.89
Tissue inhibitor of metalloproteinase-1 modulates allergic lung inflammation in murine asthma. Clin Immunol (2008) 0.88
ADAM8: a new therapeutic target for asthma. Expert Opin Ther Targets (2009) 0.86
Intracellular Cleavage of the Cx43 C-Terminal Domain by Matrix-Metalloproteases: A Novel Contributor to Inflammation? Mediators Inflamm (2015) 0.85
DNA sequence variations of metalloproteinases: their role in asthma and COPD. Postgrad Med J (2007) 0.85
Adam8 limits the development of allergic airway inflammation in mice. J Immunol (2013) 0.84
MMP induced by Gr-1+ cells are crucial for recruitment of Th cells into the airways. Eur J Immunol (2009) 0.84
Deficiency of matrix metalloproteinase-13 increases inflammation after acute lung injury. Exp Lung Res (2010) 0.84
Matrix Metalloproteinases in Non-Neoplastic Disorders. Int J Mol Sci (2016) 0.81
Profile of gene expression in a murine model of allergic bronchopulmonary aspergillosis. Infect Immun (2005) 0.78
Matrix metalloproteinase 3 promotes cellular anti-dengue virus response via interaction with transcription factor NFκB in cell nucleus. PLoS One (2014) 0.78
Matrix Metalloproteinase 9 Exerts Antiviral Activity against Respiratory Syncytial Virus. PLoS One (2015) 0.77
Regulation of the IgE response. F1000 Biol Rep (2010) 0.77
Detection and monitoring of localized matrix metalloproteinase upregulation in a murine model of asthma. Am J Physiol Lung Cell Mol Physiol (2014) 0.76
Getting to the site of inflammation: the leukocyte adhesion cascade updated. Nat Rev Immunol (2007) 17.18
A critical role for eosinophils in allergic airways remodeling. Science (2004) 5.53
MMP9 induction by vascular endothelial growth factor receptor-1 is involved in lung-specific metastasis. Cancer Cell (2002) 4.93
Resolution of airway inflammation and hyperreactivity after in vivo transfer of CD4+CD25+ regulatory T cells is interleukin 10 dependent. J Exp Med (2005) 3.48
Elastin fragments drive disease progression in a murine model of emphysema. J Clin Invest (2006) 3.11
The junctional adhesion molecule JAM-C regulates polarized transendothelial migration of neutrophils in vivo. Nat Immunol (2011) 3.04
Matrix metalloproteinase-9 in lung remodeling. Am J Respir Cell Mol Biol (2003) 2.95
The Th17 pathway in cystic fibrosis lung disease. Am J Respir Crit Care Med (2011) 2.87
Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis. J Exp Med (2009) 2.61
Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13-induced inflammation and remodeling. J Clin Invest (2002) 2.52
PECAM-1: a multi-functional molecule in inflammation and vascular biology. Arterioscler Thromb Vasc Biol (2007) 2.46
Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation. Nat Med (2008) 2.44
IL-9 governs allergen-induced mast cell numbers in the lung and chronic remodeling of the airways. Am J Respir Crit Care Med (2010) 2.36
Manipulation of allergen-induced airway remodeling by treatment with anti-TGF-beta antibody: effect on the Smad signaling pathway. J Immunol (2005) 2.22
Venular basement membranes contain specific matrix protein low expression regions that act as exit points for emigrating neutrophils. J Exp Med (2006) 2.13
Endothelial cell activation leads to neutrophil transmigration as supported by the sequential roles of ICAM-2, JAM-A, and PECAM-1. Blood (2009) 2.10
Osteopontin has a crucial role in allergic airway disease through regulation of dendritic cell subsets. Nat Med (2007) 2.08
Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo. J Exp Med (2012) 2.02
Characterization of hematopoietic progenitor mobilization in protease-deficient mice. Blood (2004) 2.01
Activin A and TGF-β promote T(H)9 cell-mediated pulmonary allergic pathology. J Allergy Clin Immunol (2012) 1.98
Targeted disruption of the matrix metalloproteinase-9 gene impairs smooth muscle cell migration and geometrical arterial remodeling. Circ Res (2002) 1.98
Fragments of extracellular matrix as mediators of inflammation. Int J Biochem Cell Biol (2007) 1.89
Of flies, mice and men: a systematic approach to understanding the early life origins of chronic lung disease. Thorax (2012) 1.88
Antineutrophil cytoplasm antibodies directed against myeloperoxidase augment leukocyte-microvascular interactions in vivo. Blood (2005) 1.86
Orchestrating house dust mite-associated allergy in the lung. Trends Immunol (2011) 1.86
Matrix metalloproteinase gelatinase B (MMP-9) coordinates and effects epithelial regeneration. J Biol Chem (2001) 1.74
Maintenance of glomerular filtration barrier integrity requires laminin alpha5. J Am Soc Nephrol (2010) 1.73
Peptide immunotherapy in allergic asthma generates IL-10-dependent immunological tolerance associated with linked epitope suppression. J Exp Med (2009) 1.73
Resolution of allergic inflammation and airway hyperreactivity is dependent upon disruption of the T1/ST2-IL-33 pathway. Am J Respir Crit Care Med (2009) 1.72
The absence of interleukin 9 does not affect the development of allergen-induced pulmonary inflammation nor airway hyperreactivity. J Exp Med (2002) 1.62
Neutrophils from MMP-9- or neutrophil elastase-deficient mice show no defect in transendothelial migration under flow in vitro. J Leukoc Biol (2002) 1.62
Strain-specific requirement for eosinophils in the recruitment of T cells to the lung during the development of allergic asthma. J Exp Med (2008) 1.59
Ablation of matrix metalloproteinase-9 increases severity of viral myocarditis in mice. Circulation (2008) 1.54
CD4+CD25+ regulatory T cells reverse established allergic airway inflammation and prevent airway remodeling. J Allergy Clin Immunol (2008) 1.51
Matrix metalloproteinases 9 and 2 are necessary for the migration of Langerhans cells and dermal dendritic cells from human and murine skin. J Immunol (2002) 1.49
JAM-A mediates neutrophil transmigration in a stimulus-specific manner in vivo: evidence for sequential roles for JAM-A and PECAM-1 in neutrophil transmigration. Blood (2007) 1.47
Pediatric severe asthma is characterized by eosinophilia and remodeling without T(H)2 cytokines. J Allergy Clin Immunol (2012) 1.45
Annexin 1-deficient neutrophils exhibit enhanced transmigration in vivo and increased responsiveness in vitro. J Leukoc Biol (2005) 1.43
Murine CD93 (C1qRp) contributes to the removal of apoptotic cells in vivo but is not required for C1q-mediated enhancement of phagocytosis. J Immunol (2004) 1.42
Junctional adhesion molecule-C regulates the early influx of leukocytes into tissues during inflammation. J Immunol (2005) 1.41
Macrophage fusion, giant cell formation, and the foreign body response require matrix metalloproteinase 9. J Leukoc Biol (2009) 1.41
Mice that lack matrix metalloproteinase-9 display delayed wound healing associated with delayed reepithelization and disordered collagen fibrillogenesis. Matrix Biol (2009) 1.40
ICAM-2 mediates neutrophil transmigration in vivo: evidence for stimulus specificity and a role in PECAM-1-independent transmigration. Blood (2006) 1.39
A site on laminin alpha 5, AQARSAASKVKVSMKF, induces inflammatory cell production of matrix metalloproteinase-9 and chemotaxis. J Immunol (2003) 1.38
Microfibrillar proteins MAGP-1 and MAGP-2 induce Notch1 extracellular domain dissociation and receptor activation. J Biol Chem (2006) 1.38
JAM-C regulates unidirectional monocyte transendothelial migration in inflammation. Blood (2007) 1.38
Overexpression of Stat3C in pulmonary epithelium protects against hyperoxic lung injury. J Immunol (2005) 1.37
Laminin isoforms and lung development: all isoforms are not equal. Dev Biol (2006) 1.37
Mouse strain modulates the role of the ciliated cell in acute tracheobronchial airway injury-distal airways. Am J Pathol (2002) 1.34
Membrane-type 1 matrix metalloproteinase is required for normal alveolar development. Dev Dyn (2005) 1.32
Clinical research in chronic obstructive pulmonary disease: needs and opportunities. Am J Respir Crit Care Med (2003) 1.32
Neutrophil heterogeneity in health and disease: a revitalized avenue in inflammation and immunity. Open Biol (2012) 1.30
A transgenic FOXJ1-Cre system for gene inactivation in ciliated epithelial cells. Am J Respir Cell Mol Biol (2007) 1.28
Migration of leukocytes through the vessel wall and beyond. Thromb Haemost (2003) 1.26
The role of the lung microbiome in health and disease. A National Heart, Lung, and Blood Institute workshop report. Am J Respir Crit Care Med (2013) 1.26
IL-25 drives remodelling in allergic airways disease induced by house dust mite. Thorax (2012) 1.26
Synergy between a plasminogen cascade and MMP-9 in autoimmune disease. J Clin Invest (2005) 1.25
Distal airways in mice exposed to cigarette smoke: Nrf2-regulated genes are increased in Clara cells. Am J Respir Cell Mol Biol (2008) 1.25
JAM family and related proteins in leukocyte migration (Vestweber series). Arterioscler Thromb Vasc Biol (2007) 1.24
Chronic inflammation and asthma. Mutat Res (2009) 1.22
Experimental autoimmune vasculitis: an animal model of anti-neutrophil cytoplasmic autoantibody-associated systemic vasculitis. Am J Pathol (2009) 1.21
Characterization of mouse alveolar epithelial cell monolayers. Am J Physiol Lung Cell Mol Physiol (2009) 1.20
Y-chromosomal insights into the genetic impact of the caste system in India. Hum Genet (2006) 1.19
Phosphatidylethanolamine-esterified eicosanoids in the mouse: tissue localization and inflammation-dependent formation in Th-2 disease. J Biol Chem (2009) 1.18
Recent developments and complexities in neutrophil transmigration. Curr Opin Hematol (2010) 1.17
PECAM-1, alpha6 integrins and neutrophil elastase cooperate in mediating neutrophil transmigration. J Cell Sci (2005) 1.16
The role of matrix metalloproteinase-9 in cigarette smoke-induced emphysema. Am J Respir Crit Care Med (2010) 1.16
Resolution of allergic airway inflammation and airway hyperreactivity is mediated by IL-17-producing {gamma}{delta}T cells. Am J Respir Crit Care Med (2010) 1.15
Epithelial laminin alpha5 is necessary for distal epithelial cell maturation, VEGF production, and alveolization in the developing murine lung. Dev Biol (2005) 1.15
Monocytes and neutrophils exhibit both distinct and common mechanisms in penetrating the vascular basement membrane in vivo. Arterioscler Thromb Vasc Biol (2009) 1.14
Venular basement membranes ubiquitously express matrix protein low-expression regions: characterization in multiple tissues and remodeling during inflammation. Am J Pathol (2009) 1.14
Expression and function of junctional adhesion molecule-C in myelinated peripheral nerves. Science (2007) 1.14
Overexpression of Smad2 drives house dust mite-mediated airway remodeling and airway hyperresponsiveness via activin and IL-25. Am J Respir Crit Care Med (2010) 1.14
IL-33 promotes airway remodeling in pediatric patients with severe steroid-resistant asthma. J Allergy Clin Immunol (2013) 1.14
Early emphysema in the tight skin and pallid mice: roles of microfibril-associated glycoproteins, collagen, and mechanical forces. Am J Respir Cell Mol Biol (2006) 1.14
Clara cells impact the pulmonary innate immune response to LPS. Am J Physiol Lung Cell Mol Physiol (2007) 1.14
Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung. Dev Biol (2002) 1.12
Cognate recognition of the endothelium induces HY-specific CD8+ T-lymphocyte transendothelial migration (diapedesis) in vivo. Blood (2003) 1.12
Ig gene-like molecule CD31 plays a nonredundant role in the regulation of T-cell immunity and tolerance. Proc Natl Acad Sci U S A (2010) 1.11
In vivo detection of acinar microstructural changes in early emphysema with (3)He lung morphometry. Radiology (2011) 1.11
The extracellular matrix protein MAGP-2 interacts with Jagged1 and induces its shedding from the cell surface. J Biol Chem (2005) 1.11
Therapeutic effect of anti-TNF-alpha antibodies in an experimental model of anti-neutrophil cytoplasm antibody-associated systemic vasculitis. J Am Soc Nephrol (2005) 1.09
Neutrophil elastase cleaves laminin-332 (laminin-5) generating peptides that are chemotactic for neutrophils. J Biol Chem (2008) 1.08